Exploiting functional domains of GRK2/3 to alter the competitive balance of pro- and anticontractile signaling in airway smooth muscle

FASEB Journal

Volumn 28, Issue 2, 2014, Pages 956-965

  Deshpande, Deepak A ^a   Yan, Huandong ^a   Kong, Kok Choi ^b   Tiegs, Brian C ^c   Morgan, Sarah J ^a   Pera, Tonio ^c   Panettieri, Reynold A ^d   Eckhart, Andrea D ^d   Penn, Raymond B ^a,b,c  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b WAKE FOREST UNIVERSITY HEALTH SCIENCES   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Asthma; Bronchodilation; Desensitization; G protein coupled receptor; agonist

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; G PROTEIN COUPLED RECEPTOR KINASE 2; G PROTEIN COUPLED RECEPTOR KINASE 3; HISTAMINE; METHACHOLINE; PHOSPHATIDYLINOSITIDE; THROMBIN; ADRBK1 PROTEIN, HUMAN; ADRBK2 PROTEIN, HUMAN; CALCIUM; CYCLIC AMP; G PROTEIN COUPLED RECEPTOR; SMALL INTERFERING RNA;

AIRWAY SMOOTH MUSCLE; ANIMAL EXPERIMENT; ARTICLE; CALCIUM MOBILIZATION; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROLYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE RELAXATION; ASTHMA; BRONCHODILATATION; CHEMISTRY; CYTOLOGY; DESENSITIZATION; G-PROTEIN-COUPLED RECEPTOR; METABOLISM; PHYSIOLOGY; RESPIRATORY SYSTEM; Β-AGONIST;

ASTHMA; BRONCHODILATION; DESENSITIZATION; G-PROTEIN-COUPLED RECEPTOR; Β-AGONIST;

CALCIUM; CYCLIC AMP; G-PROTEIN-COUPLED RECEPTOR KINASE 2; G-PROTEIN-COUPLED RECEPTOR KINASE 3; HUMANS; MUSCLE, SMOOTH; RECEPTORS, G-PROTEIN-COUPLED; RESPIRATORY SYSTEM; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84897077903     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.13-240226     Document Type: Article

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