Anti-mitogenic effects of β-agonists and PGE2on airway smooth muscle are PKA dependent

FASEB Journal

Volumn 25, Issue 1, 2011, Pages 389-397

  Yan, Huandong ^a   Deshpande, Deepak A ^a   Misior, Anna M ^b   Miles, Matthew C ^b   Saxena, Himansh ^a   Riemer, Ellen C ^c   Pascual, Rodolfo M ^b   Panettieri, Reynold A ^d   Penn, Raymond B ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b WAKE FOREST UNIVERSITY HEALTH SCIENCES   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Airway remodeling; Asthma; Cell proliferation; Cyclic AMP; G protein coupled receptor

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CYCLIC AMP DEPENDENT PROTEIN KINASE; DNA; EPIDERMAL GROWTH FACTOR; G PROTEIN COUPLED RECEPTOR; ISOPRENALINE; PHOSPHATIDYLINOSITOL 3 KINASE; PROSTAGLANDIN E2; PROTEIN P42; PROTEIN P44; SALBUTAMOL; SALMETEROL;

AIRWAY SMOOTH MUSCLE; ANTIMITOGENIC ACTIVITY; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; DRUG ACTIVITY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN TISSUE; MUSCLE GROWTH; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SMOOTH MUSCLE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADRENERGIC BETA-2 RECEPTOR AGONISTS; ALBUTEROL; BRONCHODILATOR AGENTS; CELL PROLIFERATION; CELLS, CULTURED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DINOPROSTONE; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; GREEN FLUORESCENT PROTEINS; HUMANS; IMMUNOBLOTTING; ISOPROTERENOL; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MUSCLE, SMOOTH; MYOCYTES, SMOOTH MUSCLE; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; TIME FACTORS; TRACHEA; TRANSFECTION;

EID: 79251586229     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.10-164798     Document Type: Article

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