Bitter tasting compounds dilate airways by inhibiting airway smooth muscle calcium oscillations and calcium sensitivity

British Journal of Pharmacology

Volumn 171, Issue 3, 2014, Pages 646-662

  Tan, Xiahui ^a   Sanderson, Michael J ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

2 adrenergic receptor agonists; 2 photon microscopy; asthma; mouse lung slice; TAS2R

Indexed keywords

ARISTOLOCHIC ACID; CAFFEINE; CALCIUM; CHLOROQUINE; INOSITOL 1,4,5 TRISPHOSPHATE; METHACHOLINE; PROTEIN; PROTEIN INHIBITOR; QUININE; RYANODINE; SACCHARIN; TAS2R PROTEIN; TAS2R10 AGONIST; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREATHING MUSCLE; BRONCHOCONSTRICTION; BRONCHODILATATION; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; FLUORESCENCE MICROSCOPY; IMMUNOCYTOCHEMISTRY; MOUSE; NONHUMAN; PHASE CONTRAST MICROSCOPY; PHOTOLYSIS; PRIORITY JOURNAL; SMOOTH MUSCLE; TASTE BUD;

2-PHOTON MICROSCOPY; ASTHMA; MOUSE LUNG SLICE; TAS2R; Β2-ADRENERGIC RECEPTOR AGONISTS;

AIRWAY RESISTANCE; ANIMALS; BRONCHODILATOR AGENTS; CAFFEINE; CALCIUM CHANNEL BLOCKERS; CALCIUM SIGNALING; CHLOROQUINE; DRUG RESISTANCE; FEMALE; INOSITOL 1,4,5-TRISPHOSPHATE; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; LUNG; MICE; MICE, INBRED BALB C; MUSCLE RELAXATION; MUSCLE, SMOOTH; PHOSPHODIESTERASE INHIBITORS; QUATERNARY AMMONIUM COMPOUNDS; QUININE; RECEPTORS, G-PROTEIN-COUPLED; RYANODINE; TASTE;

EID: 84892430130     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12460     Document Type: Article

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