Inhibition of mTOR by apigenin in UVB-irradiated keratinocytes: A new implication of skin cancer prevention

Cellular Signalling

Volumn 28, Issue 5, 2016, Pages 460-468

  Bridgeman, Bryan B ^a   Wang, Pu ^b   Ye, Boping ^b   Pelling, Jill C ^a   Volpert, Olga V ^a   Tong, Xin ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Akt; AMPK; Apigenin; Autophagy; MTOR; UVB

Indexed keywords

APIGENIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; ANTINEOPLASTIC AGENT; TARGET OF RAPAMYCIN KINASE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER PREVENTION; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; KERATINOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION PROTECTION; SIGNAL TRANSDUCTION; SKIN CANCER; ULTRAVIOLET B RADIATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; CELL CYCLE; CELL LINE; CYTOLOGY; DRUG EFFECTS; ENZYMOLOGY; METABOLISM; RADIATION RESPONSE; SKIN NEOPLASMS; ULTRAVIOLET RADIATION;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTICARCINOGENIC AGENTS; APIGENIN; APOPTOSIS; AUTOPHAGY; CELL CYCLE; CELL LINE; CELL PROLIFERATION; KERATINOCYTES; MICE, INBRED BALB C; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; TOR SERINE-THREONINE KINASES; ULTRAVIOLET RAYS;

EID: 84958522787     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2016.02.008     Document Type: Article

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