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Volumn 160, Issue 2, 2009, Pages 442-445

Activation of the mammalian target of rapamycin signalling pathway in epidermal tumours and its correlation with cyclin-dependent kinase 2

Author keywords

AKT; Cyclin dependent kinase 2; Epidermal tumour; Mammalian target of rapamycin

Indexed keywords

CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 2 INHIBITOR; INITIATION FACTOR 4E BINDING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; PROTEIN S6;

EID: 58349122896     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2008.08903.x     Document Type: Article
Times cited : (43)

References (15)
  • 1
    • 2342559981 scopus 로고    scopus 로고
    • The TOR pathway: A target for cancer therapy
    • Bjornsti M, Houghton PJ. The TOR pathway: a target for cancer therapy. Nat Rev Cancer 2004 4 : 335 8.
    • (2004) Nat Rev Cancer , vol.4 , pp. 335-8
    • Bjornsti, M.1    Houghton, P.J.2
  • 2
    • 8344281974 scopus 로고    scopus 로고
    • Targeting the molecular target of rapamycin (mTOR)
    • Rowinsky EK. Targeting the molecular target of rapamycin (mTOR). Curr Opin Oncol 2004 16 : 564 75.
    • (2004) Curr Opin Oncol , vol.16 , pp. 564-75
    • Rowinsky, E.K.1
  • 3
    • 0034947869 scopus 로고    scopus 로고
    • Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin
    • Takano A, Usui I, Haruta T et al. Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin. Mol Cell Biol 2001 21 : 5050 62.
    • (2001) Mol Cell Biol , vol.21 , pp. 5050-62
    • Takano, A.1    Usui, I.2    Haruta, T.3
  • 4
    • 4544223402 scopus 로고    scopus 로고
    • The role of PTEN and its signalling pathways, including AKT, in breast cancer; An assessment of relationships with other prognostic factors and with outcome
    • Panigrahi AR, Pinder SE, Chan SY et al. The role of PTEN and its signalling pathways, including AKT, in breast cancer; an assessment of relationships with other prognostic factors and with outcome. J Pathol 2004 204 : 93 100.
    • (2004) J Pathol , vol.204 , pp. 93-100
    • Panigrahi, A.R.1    Pinder, S.E.2    Chan, S.Y.3
  • 5
    • 0033604521 scopus 로고    scopus 로고
    • Ribosomal S6 kinase signaling and the control of translation
    • Dufner A, Thomas J. Ribosomal S6 kinase signaling and the control of translation. Exp Cell Res 1999 253 : 100 9.
    • (1999) Exp Cell Res , vol.253 , pp. 100-9
    • Dufner, A.1    Thomas, J.2
  • 6
    • 28244469041 scopus 로고    scopus 로고
    • Redox regulation of the nutrient-sensitive raptor-mTOR pathway and complex
    • Sarbassov DD, Sabatini DM. Redox regulation of the nutrient-sensitive raptor-mTOR pathway and complex. J Biol Chem 2005 280 : 39505 9.
    • (2005) J Biol Chem , vol.280 , pp. 39505-9
    • Sarbassov, D.D.1    Sabatini, D.M.2
  • 7
    • 31444434449 scopus 로고    scopus 로고
    • MTOR: Implications for cancer and anticancer therapy
    • Petroulakis E, Mamane Y, Bacquer OL et al. mTOR: implications for cancer and anticancer therapy. Br J Cancer 2006 94 : 195 9.
    • (2006) Br J Cancer , vol.94 , pp. 195-9
    • Petroulakis, E.1    Mamane, Y.2    Bacquer, O.L.3
  • 8
    • 27744576150 scopus 로고    scopus 로고
    • Proliferative markers as prognostic and predictive tools in early breast cancer: Where are we now?
    • Colozza M, Azambuja E, Cardoso F et al. Proliferative markers as prognostic and predictive tools in early breast cancer: where are we now? Ann Oncol 2005 16 : 1723 39.
    • (2005) Ann Oncol , vol.16 , pp. 1723-39
    • Colozza, M.1    Azambuja, E.2    Cardoso, F.3
  • 9
    • 0041379477 scopus 로고    scopus 로고
    • Expression of cyclins E, A, and B, and prognosis in lymph node-negative breast cancer
    • Kuhling H, Alm P, Olsson H et al. Expression of cyclins E, A, and B, and prognosis in lymph node-negative breast cancer. J Pathol 2003 199 : 424 31.
    • (2003) J Pathol , vol.199 , pp. 424-31
    • Kuhling, H.1    Alm, P.2    Olsson, H.3
  • 11
    • 0038724743 scopus 로고    scopus 로고
    • Regulators of G1 cyclin-dependent kinases and cancers
    • Lee M-H, Yang H-Y. Regulators of G1 cyclin-dependent kinases and cancers. Cancer Metast Rev 2003 22 : 435 49.
    • (2003) Cancer Metast Rev , vol.22 , pp. 435-49
    • Lee, M.-H.1    Yang, H.-Y.2
  • 12
    • 33747043505 scopus 로고    scopus 로고
    • Expression of insulin-like growth factor-1 receptor, p-AKT and p-ERK1/2 protein in extramammary Paget's disease
    • Liu H, Moroi Y, Yasumoto S et al. Expression of insulin-like growth factor-1 receptor, p-AKT and p-ERK1/2 protein in extramammary Paget's disease. Br J Dermatol 2006 155 : 586 91.
    • (2006) Br J Dermatol , vol.155 , pp. 586-91
    • Liu, H.1    Moroi, Y.2    Yasumoto, S.3
  • 13
    • 12344262762 scopus 로고    scopus 로고
    • MTOR, translational control and human disease
    • Tee AR, Blenis J. mTOR, translational control and human disease. Semin Cell Dev Biol 2005 16 : 29 37.
    • (2005) Semin Cell Dev Biol , vol.16 , pp. 29-37
    • Tee, A.R.1    Blenis, J.2
  • 14
    • 43149102480 scopus 로고    scopus 로고
    • Akt-mediated phosphorylation of CDK2 regulates its dual role in cell cycle progression and apoptosis
    • Maddika S, Ande SR, Wiechec E et al. Akt-mediated phosphorylation of CDK2 regulates its dual role in cell cycle progression and apoptosis. J Cell Sci 2008 121 : 979 88.
    • (2008) J Cell Sci , vol.121 , pp. 979-88
    • Maddika, S.1    Ande, S.R.2    Wiechec, E.3
  • 15
    • 39049086308 scopus 로고    scopus 로고
    • Determination of the specific activity of CDK1 and CDK2 as a novel prognostic indicator for early breast cancer
    • Kim SJ, Nakayama S, Miyoshi Y et al. Determination of the specific activity of CDK1 and CDK2 as a novel prognostic indicator for early breast cancer. Ann Oncol 2008 19 : 68 72.
    • (2008) Ann Oncol , vol.19 , pp. 68-72
    • Kim, S.J.1    Nakayama, S.2    Miyoshi, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.