The cationic peptide LL-37 binds Mac-1 (CD11b/CD18) with a low dissociation rate and promotes phagocytosis

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1864, Issue 5, 2016, Pages 471-478

  Zhang, Xianwei ^a   Bajic, Goran ^a   Andersen, Gregers R ^a   Christiansen, Stig Hill ^a   Vorup Jensen, Thomas ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

Cell adhesion, anti microbial peptides; Ligand binding kinetics; Phagocytosis; von Willebrand Factor (vWF) Type A domain; 2 (CD18) integrins

Indexed keywords

CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; CD11B ANTIGEN; COMPLEMENT COMPONENT C3D; CORE PEPTIDE FK 13; PEPTIDE FRAGMENT; UNCLASSIFIED DRUG; ANTIMICROBIAL CATIONIC PEPTIDE; CAP18 LIPOPOLYSACCHARIDE-BINDING PROTEIN; CD18 ANTIGEN; PROTEIN BINDING;

ARTICLE; BINDING KINETICS; CELL ADHESION; CELL VIABILITY; COMPARATIVE STUDY; CONTROLLED STUDY; DISSOCIATION CONSTANT; HUMAN; HUMAN CELL; LIGAND BINDING; PERIPHERAL BLOOD MONONUCLEAR CELL; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; QUANTITATIVE ASSAY; AMINO ACID SEQUENCE; CHEMISTRY; GENETICS; INNATE IMMUNITY; KINETICS; LEUKOCYTE; METABOLISM; NEUTROPHIL;

AMINO ACID SEQUENCE; ANTIGENS, CD18; ANTIMICROBIAL CATIONIC PEPTIDES; CELL ADHESION; HUMANS; IMMUNITY, INNATE; KINETICS; LEUKOCYTES; MACROPHAGE-1 ANTIGEN; NEUTROPHILS; PHAGOCYTOSIS; PROTEIN BINDING;

EID: 84958240889     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2016.02.013     Document Type: Article

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