Structural insight on the recognition of surface-bound opsonins by the integrin i domain of complement receptor 3

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 41, 2013, Pages 16426-16431

  Bajic, Goran ^a   Yatime, Laure ^a   Sim, Robert B ^b   Vorup Jensen, Thomas ^c   Andersen, Gregers R ^a  

^a Department of Molecular Biology and Genetics ^*  (United States)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c AARHUS UNIVERSITY   (Denmark)

Author keywords

Innate immunity; Integrin receptor; Phagocytosis; Structural biology

Indexed keywords

ASPARTIC ACID; CD11B ANTIGEN; COMPLEMENT; COMPLEMENT COMPONENT C3B; COMPLEMENT COMPONENT C3D; COMPLEMENT RECEPTOR; COMPLEMENT RECEPTOR 2; GLUTAMIC ACID; INTEGRIN 1 DOMAIN OF COMPLEMENT RECEPTOR 3; METAL ION; OPSONIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN ANTIBODY COMPLEX; ANTIGEN PRESENTING CELL; ARTICLE; B LYMPHOCYTE; BINDING AFFINITY; BINDING SITE; COMPLEMENT SYSTEM; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; FOLLICULAR DENDRITIC CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MACROPHAGE; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; NONHUMAN; OPSONIZATION; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECONDARY STRUCTURE; RECEPTOR BINDING; STRUCTURE ANALYSIS;

INNATE IMMUNITY; INTEGRIN RECEPTOR; PHAGOCYTOSIS; STRUCTURAL BIOLOGY;

COMPLEMENT C3B; COMPUTATIONAL BIOLOGY; ESCHERICHIA COLI; HUMANS; IMMUNITY, INNATE; MACROPHAGE-1 ANTIGEN; MACROPHAGES; MODELS, MOLECULAR; OPSONIN PROTEINS; PHAGOCYTOSIS; PROTEIN CONFORMATION;

EID: 84885333791     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1311261110     Document Type: Article

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