Mas-related gene X2 (MrgX2) is a novel G protein-coupled receptor for the antimicrobial peptide LL-37 in human mast cells: Resistance to receptor phosphorylation, desensitization, and internalization

Journal of Biological Chemistry

Volumn 286, Issue 52, 2011, Pages 44739-44749

  Subramanian, Hariharan ^a   Gupta, Kshitij ^a   Guo, Qiang ^a   Price, Ryan ^a   Ali, Hydar ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS; ANTIBACTERIAL PEPTIDES; ANTIMICROBIAL PEPTIDE; CELL SURFACES; CHEMOKINES; DEGRANULATION; DORSAL ROOT GANGLIA; G PROTEIN COUPLED RECEPTORS; G PROTEIN-COUPLED RECEPTOR KINASE; HUMAN MAST CELLS; MAST CELLS; SUBSTANTIAL REDUCTION; TUMOR METASTASIS; WOUND HEALING;

BIOCHEMISTRY; CELL CULTURE; CELL MEMBRANES; GENES; MICROORGANISMS; PATHOLOGY; PEPTIDES; PHOSPHORYLATION;

ENDOTHELIAL CELLS;

CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR KINASE 2; G PROTEIN COUPLED RECEPTOR KINASE 3; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MAS RELATED GENE X2 PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM MOBILIZATION; CD34 SELECTION; CELL LINE; CHEMOTAXIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DESENSITIZATION; HUMAN; HUMAN CELL; INTERNALIZATION; MAST CELL; MAST CELL DEGRANULATION; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION;

ANTIMICROBIAL CATIONIC PEPTIDES; CALCIUM; CALCIUM SIGNALING; CELL DEGRANULATION; CELL LINE; GENE KNOCKDOWN TECHNIQUES; HUMANS; MAST CELLS; NERVE TISSUE PROTEINS; PHOSPHORYLATION; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROPEPTIDE;

EID: 84455172954     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.277152     Document Type: Article

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