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Volumn 18, Issue 3, 2016, Pages 251-258

Tumor-associated macrophages in cancers

Author keywords

Cancer; Tumor associated macrophages

Indexed keywords

CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CX3CR1; COLONY STIMULATING FACTOR 1; CXCL16 CHEMOKINE; GELATINASE B; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; INTERLEUKIN 6; MACROPHAGE DERIVED CHEMOKINE; MACROPHAGE MIGRATION INHIBITION FACTOR; MATRIX METALLOPROTEINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; STAT3 PROTEIN; TRANSFORMING GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN;

EID: 84958160903     PISSN: 1699048X     EISSN: 16993055     Source Type: Journal    
DOI: 10.1007/s12094-015-1373-0     Document Type: Review
Times cited : (107)

References (78)
  • 1
    • 80355131976 scopus 로고    scopus 로고
    • Protective and pathogenic functions of macrophage subsets
    • COI: 1:CAS:528:DC%2BC3MXhtlWltb%2FE, PID: 21997792
    • Murray PJ, Wynn TA. Protective and pathogenic functions of macrophage subsets. Nat Rev Immunol. 2011;11(11):723–37. doi:10.1038/nri3073.
    • (2011) Nat Rev Immunol , vol.11 , Issue.11 , pp. 723-737
    • Murray, P.J.1    Wynn, T.A.2
  • 2
    • 77950944395 scopus 로고    scopus 로고
    • Macrophages, innate immunity and cancer: balance, tolerance, and diversity
    • COI: 1:CAS:528:DC%2BC3cXks1Srtr8%3D, PID: 20144856
    • Mantovani A, Sica A. Macrophages, innate immunity and cancer: balance, tolerance, and diversity. Curr Opin Immunol. 2010;22(2):231–7. doi:10.1016/j.coi.2010.01.009.
    • (2010) Curr Opin Immunol , vol.22 , Issue.2 , pp. 231-237
    • Mantovani, A.1    Sica, A.2
  • 3
    • 67650151005 scopus 로고    scopus 로고
    • Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability
    • COI: 1:CAS:528:DC%2BD1MXot1CisL8%3D, PID: 19468060
    • Colotta F, Allavena P, Sica A, Garlanda C, Mantovani A. Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis. 2009;30(7):1073–81. doi:10.1093/carcin/bgp127.
    • (2009) Carcinogenesis , vol.30 , Issue.7 , pp. 1073-1081
    • Colotta, F.1    Allavena, P.2    Sica, A.3    Garlanda, C.4    Mantovani, A.5
  • 4
    • 77956976681 scopus 로고    scopus 로고
    • Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
    • COI: 1:CAS:528:DC%2BC3cXhtFyhtrrL, PID: 20856220
    • Biswas SK, Mantovani A. Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat Immunol. 2010;11(10):889–96. doi:10.1038/ni.1937.
    • (2010) Nat Immunol , vol.11 , Issue.10 , pp. 889-896
    • Biswas, S.K.1    Mantovani, A.2
  • 5
    • 84859508307 scopus 로고    scopus 로고
    • A lineage of myeloid cells independent of Myb and hematopoietic stem cells
    • COI: 1:CAS:528:DC%2BC38XkvV2rsrc%3D, PID: 22442384
    • Schulz C, Gomez Perdiguero E, Chorro L, Szabo-Rogers H, Cagnard N, Kierdorf K, et al. A lineage of myeloid cells independent of Myb and hematopoietic stem cells. Science. 2012;336(6077):86–90. doi:10.1126/science.1219179.
    • (2012) Science , vol.336 , Issue.6077 , pp. 86-90
    • Schulz, C.1    Gomez Perdiguero, E.2    Chorro, L.3    Szabo-Rogers, H.4    Cagnard, N.5    Kierdorf, K.6
  • 6
    • 84904875085 scopus 로고    scopus 로고
    • Myb-independent macrophages: a family of cells that develops with their tissue of residence and is involved in its homeostasis
    • Gomez Perdiguero E, Geissmann F. Myb-independent macrophages: a family of cells that develops with their tissue of residence and is involved in its homeostasis. Cold Spring Harb Symp Quant Biol. 2013;78:91–100. doi:10.1101/sqb.2013.78.020032.
    • (2013) Cold Spring Harb Symp Quant Biol , vol.78 , pp. 91-100
    • Gomez Perdiguero, E.1    Geissmann, F.2
  • 7
    • 84857883847 scopus 로고    scopus 로고
    • Macrophage plasticity and polarization: in vivo veritas
    • COI: 1:CAS:528:DC%2BC38XjsV2ms7g%3D, PID: 22378047
    • Sica A, Mantovani A. Macrophage plasticity and polarization: in vivo veritas. J Clin Invest. 2012;122(3):787–95. doi:10.1172/JCI59643.
    • (2012) J Clin Invest. , vol.122 , Issue.3 , pp. 787-795
    • Sica, A.1    Mantovani, A.2
  • 8
    • 84907176451 scopus 로고    scopus 로고
    • Isoliquiritigenin, a flavonoid from licorice, blocks M2 macrophage polarization in colitis-associated tumorigenesis through downregulating PGE2 and IL-6
    • COI: 1:CAS:528:DC%2BC2cXhsVGgtLjN, PID: 25026504
    • Zhao H, Zhang X, Chen X, Li Y, Ke Z, Tang T, et al. Isoliquiritigenin, a flavonoid from licorice, blocks M2 macrophage polarization in colitis-associated tumorigenesis through downregulating PGE2 and IL-6. Toxicol Appl Pharmacol. 2014;279(3):311–21. doi:10.1016/j.taap.2014.07.001.
    • (2014) Toxicol Appl Pharmacol , vol.279 , Issue.3 , pp. 311-321
    • Zhao, H.1    Zhang, X.2    Chen, X.3    Li, Y.4    Ke, Z.5    Tang, T.6
  • 9
    • 84925799247 scopus 로고    scopus 로고
    • Transcriptomic analysis of human polarized macrophages: more than one role of alternative activation?
    • PID: 25799240
    • Derlindati E, Dei Cas A, Montanini B, Spigoni V, Curella V, Aldigeri R, et al. Transcriptomic analysis of human polarized macrophages: more than one role of alternative activation? PLoS One. 2015;10(3):e0119751. doi:10.1371/journal.pone.0119751.
    • (2015) PLoS One , vol.10 , Issue.3 , pp. e0119751
    • Derlindati, E.1    Dei Cas, A.2    Montanini, B.3    Spigoni, V.4    Curella, V.5    Aldigeri, R.6
  • 10
    • 84867402916 scopus 로고    scopus 로고
    • Modulation of heat shock proteins during macrophage differentiation
    • COI: 1:CAS:528:DC%2BC38Xhtleiu7nO, PID: 22706319
    • Fagone P, Di Rosa M, Palumbo M, De Gregorio C, Nicoletti F, Malaguarnera L. Modulation of heat shock proteins during macrophage differentiation. Inflamm Res. 2012;61(10):1131–9. doi:10.1007/s00011-012-0506-y.
    • (2012) Inflamm Res , vol.61 , Issue.10 , pp. 1131-1139
    • Fagone, P.1    Di Rosa, M.2    Palumbo, M.3    De Gregorio, C.4    Nicoletti, F.5    Malaguarnera, L.6
  • 11
    • 84919346877 scopus 로고    scopus 로고
    • Tumour-associated macrophage polarisation and re-education with immunotherapy
    • PID: 25553381
    • Josephs DH, Bax HJ, Karagiannis SN. Tumour-associated macrophage polarisation and re-education with immunotherapy. Front Biosci (Elite Ed). 2015;7:293–308.
    • (2015) Front Biosci (Elite Ed). , vol.7 , pp. 293-308
    • Josephs, D.H.1    Bax, H.J.2    Karagiannis, S.N.3
  • 12
    • 84891906271 scopus 로고    scopus 로고
    • A lovastatin-elicited genetic program inhibits M2 macrophage polarization and enhances T cell infiltration into spontaneous mouse mammary tumors
    • PID: 24317954
    • Mira E, Carmona-Rodriguez L, Tardaguila M, Azcoitia I, Gonzalez-Martin A, Almonacid L, et al. A lovastatin-elicited genetic program inhibits M2 macrophage polarization and enhances T cell infiltration into spontaneous mouse mammary tumors. Oncotarget. 2013;4(12):2288–301.
    • (2013) Oncotarget. , vol.4 , Issue.12 , pp. 2288-2301
    • Mira, E.1    Carmona-Rodriguez, L.2    Tardaguila, M.3    Azcoitia, I.4    Gonzalez-Martin, A.5    Almonacid, L.6
  • 13
    • 76249095169 scopus 로고    scopus 로고
    • Development of monocytes, macrophages, and dendritic cells
    • COI: 1:CAS:528:DC%2BC3cXhtlyhsrw%3D, PID: 20133564
    • Geissmann F, Manz MG, Jung S, Sieweke MH, Merad M, Ley K. Development of monocytes, macrophages, and dendritic cells. Science. 2010;327(5966):656–61. doi:10.1126/science.1178331.
    • (2010) Science , vol.327 , Issue.5966 , pp. 656-661
    • Geissmann, F.1    Manz, M.G.2    Jung, S.3    Sieweke, M.H.4    Merad, M.5    Ley, K.6
  • 14
    • 84924618022 scopus 로고    scopus 로고
    • PTEN inhibits macrophage polarization from M1 to M2 through CCL2 and VEGF-A reduction and NHERF-1 synergism
    • COI: 1:CAS:528:DC%2BC2MXhvFWls7nM, PID: 25756512
    • Li N, Qin J, Lan L, Zhang H, Liu F, Wu Z, et al. PTEN inhibits macrophage polarization from M1 to M2 through CCL2 and VEGF-A reduction and NHERF-1 synergism. Cancer Biol Ther. 2015;16(2):297–306. doi:10.1080/15384047.2014.1002353.
    • (2015) Cancer Biol Ther , vol.16 , Issue.2 , pp. 297-306
    • Li, N.1    Qin, J.2    Lan, L.3    Zhang, H.4    Liu, F.5    Wu, Z.6
  • 15
    • 84855817522 scopus 로고    scopus 로고
    • Immunology in the clinic review series; focus on cancer: tumour-associated macrophages: undisputed stars of the inflammatory tumour microenvironment
    • COI: 1:CAS:528:DC%2BC38XitlWit7c%3D, PID: 22235995
    • Allavena P, Mantovani A. Immunology in the clinic review series; focus on cancer: tumour-associated macrophages: undisputed stars of the inflammatory tumour microenvironment. Clin Exp Immunol. 2012;167(2):195–205. doi:10.1111/j.1365-2249.2011.04515.x.
    • (2012) Clin Exp Immunol , vol.167 , Issue.2 , pp. 195-205
    • Allavena, P.1    Mantovani, A.2
  • 16
    • 77958187950 scopus 로고    scopus 로고
    • Stromal macrophage expressing CD204 is associated with tumor aggressiveness in lung adenocarcinoma
    • PID: 20802348
    • Ohtaki Y, Ishii G, Nagai K, Ashimine S, Kuwata T, Hishida T, et al. Stromal macrophage expressing CD204 is associated with tumor aggressiveness in lung adenocarcinoma. J Thorac Oncol. 2010;5(10):1507–15. doi:10.1097/JTO.0b013e3181eba692.
    • (2010) J Thorac Oncol. , vol.5 , Issue.10 , pp. 1507-1515
    • Ohtaki, Y.1    Ishii, G.2    Nagai, K.3    Ashimine, S.4    Kuwata, T.5    Hishida, T.6
  • 18
    • 84922051656 scopus 로고    scopus 로고
    • Macrophage activation and its role in repair and pathology after spinal cord injury
    • PID: 25578260
    • Gensel JC, Zhang B. Macrophage activation and its role in repair and pathology after spinal cord injury. Brain Res. 2015;. doi:10.1016/j.brainres.2014.12.045.
    • (2015) Brain Res
    • Gensel, J.C.1    Zhang, B.2
  • 19
    • 70350728931 scopus 로고    scopus 로고
    • Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation
    • COI: 1:CAS:528:DC%2BD1MXhtlyjs7vL, PID: 19741157
    • Solinas G, Germano G, Mantovani A, Allavena P. Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation. J Leukoc Biol. 2009;86(5):1065–73. doi:10.1189/jlb.0609385.
    • (2009) J Leukoc Biol , vol.86 , Issue.5 , pp. 1065-1073
    • Solinas, G.1    Germano, G.2    Mantovani, A.3    Allavena, P.4
  • 20
    • 33645760428 scopus 로고    scopus 로고
    • Ovarian cancer cells polarize macrophages toward a tumor-associated phenotype
    • COI: 1:CAS:528:DC%2BD28XjtV2gt7k%3D, PID: 16585599
    • Hagemann T, Wilson J, Burke F, Kulbe H, Li NF, Pluddemann A, et al. Ovarian cancer cells polarize macrophages toward a tumor-associated phenotype. J immunol. 2006;176(8):5023–32.
    • (2006) J immunol , vol.176 , Issue.8 , pp. 5023-5032
    • Hagemann, T.1    Wilson, J.2    Burke, F.3    Kulbe, H.4    Li, N.F.5    Pluddemann, A.6
  • 21
    • 79953281969 scopus 로고    scopus 로고
    • Engagement of the mannose receptor by tumoral mucins activates an immune suppressive phenotype in human tumor-associated macrophages
    • COI: 1:STN:280:DC%2BC3M3gsVKnsg%3D%3D, PID: 21331365
    • Allavena P, Chieppa M, Bianchi G, Solinas G, Fabbri M, Laskarin G, et al. Engagement of the mannose receptor by tumoral mucins activates an immune suppressive phenotype in human tumor-associated macrophages. Clin Dev Immunol. 2010;2010:547179. doi:10.1155/2010/547179.
    • (2010) Clin Dev Immunol. , vol.2010 , pp. 547179
    • Allavena, P.1    Chieppa, M.2    Bianchi, G.3    Solinas, G.4    Fabbri, M.5    Laskarin, G.6
  • 22
    • 84928226005 scopus 로고    scopus 로고
    • The interaction of anticancer therapies with tumor-associated macrophages
    • Mantovani A, Allavena P. The interaction of anticancer therapies with tumor-associated macrophages. J Exp Med. 2015;. doi:10.1084/jem.20150295.
    • (2015) J Exp Med
    • Mantovani, A.1    Allavena, P.2
  • 23
    • 77950950894 scopus 로고    scopus 로고
    • Macrophage diversity enhances tumor progression and metastasis
    • COI: 1:CAS:528:DC%2BC3cXlsVSgtLc%3D, PID: 20371344
    • Qian BZ, Pollard JW. Macrophage diversity enhances tumor progression and metastasis. Cell. 2010;141(1):39–51. doi:10.1016/j.cell.2010.03.014.
    • (2010) Cell , vol.141 , Issue.1 , pp. 39-51
    • Qian, B.Z.1    Pollard, J.W.2
  • 24
    • 84942911921 scopus 로고    scopus 로고
    • Cancers with higher density of tumor-associated macrophages were associated with poor survival rates
    • Jung KY, Cho SW, Kim YA, Kim D, Oh BC, Park DJ, et al. Cancers with higher density of tumor-associated macrophages were associated with poor survival rates. J Pathol Transl Med. 2015;. doi:10.4132/jptm.2015.06.01.
    • (2015) J Pathol Transl Med
    • Jung, K.Y.1    Cho, S.W.2    Kim, Y.A.3    Kim, D.4    Oh, B.C.5    Park, D.J.6
  • 25
    • 84916196163 scopus 로고    scopus 로고
    • Hepatocellular carcinomas promote tumor-associated macrophage M2-polarization via increased B7-H3 expression
    • COI: 1:CAS:528:DC%2BC2MXksVyisro%3D, PID: 25370943
    • Kang FB, Wang L, Li D, Zhang YG, Sun DX. Hepatocellular carcinomas promote tumor-associated macrophage M2-polarization via increased B7-H3 expression. Oncol Rep. 2015;33(1):274–82. doi:10.3892/or.2014.3587.
    • (2015) Oncol Rep , vol.33 , Issue.1 , pp. 274-282
    • Kang, F.B.1    Wang, L.2    Li, D.3    Zhang, Y.G.4    Sun, D.X.5
  • 26
    • 84913580379 scopus 로고    scopus 로고
    • Tumor-associated macrophages produce interleukin 6 and signal via STAT3 to promote expansion of human hepatocellular carcinoma stem cells
    • COI: 1:CAS:528:DC%2BC2cXhvFOgsr%2FL, PID: 25181692
    • Wan S, Zhao E, Kryczek I, Vatan L, Sadovskaya A, Ludema G, et al. Tumor-associated macrophages produce interleukin 6 and signal via STAT3 to promote expansion of human hepatocellular carcinoma stem cells. Gastroenterology. 2014;147(6):1393–404. doi:10.1053/j.gastro.2014.08.039.
    • (2014) Gastroenterology , vol.147 , Issue.6 , pp. 1393-1404
    • Wan, S.1    Zhao, E.2    Kryczek, I.3    Vatan, L.4    Sadovskaya, A.5    Ludema, G.6
  • 27
    • 84928238081 scopus 로고    scopus 로고
    • B7-H3 promotes aggression and invasion of hepatocellular carcinoma by targeting epithelial-to-mesenchymal transition via JAK2/STAT3/Slug signaling pathway
    • PID: 25908926
    • Kang FB, Wang L, Jia HC, Li D, Li HJ, Zhang YG, et al. B7-H3 promotes aggression and invasion of hepatocellular carcinoma by targeting epithelial-to-mesenchymal transition via JAK2/STAT3/Slug signaling pathway. Cancer Cell Int. 2015;15:45. doi:10.1186/s12935-015-0195-z.
    • (2015) Cancer Cell Int , vol.15 , pp. 45
    • Kang, F.B.1    Wang, L.2    Jia, H.C.3    Li, D.4    Li, H.J.5    Zhang, Y.G.6
  • 28
    • 33947528384 scopus 로고    scopus 로고
    • Snail silencing effectively suppresses tumour growth and invasiveness
    • COI: 1:CAS:528:DC%2BD2sXjtlWgtbY%3D, PID: 17043660
    • Olmeda D, Jorda M, Peinado H, Fabra A, Cano A. Snail silencing effectively suppresses tumour growth and invasiveness. Oncogene. 2007;26(13):1862–74. doi:10.1038/sj.onc.1209997.
    • (2007) Oncogene , vol.26 , Issue.13 , pp. 1862-1874
    • Olmeda, D.1    Jorda, M.2    Peinado, H.3    Fabra, A.4    Cano, A.5
  • 29
    • 84939887236 scopus 로고    scopus 로고
    • Association of cagA positive Helicobacter pylori infection and laryngeal squamous cell carcinoma: a pcr approach
    • PID: 25621254
    • Amizadeh M, Shamsadini A, Arabzadeh A, Jazayeri S. Association of cagA positive Helicobacter pylori infection and laryngeal squamous cell carcinoma: a pcr approach. Indian J Otolaryngol Head Neck Surg. 2015;67(Suppl 1):51–5. doi:10.1007/s12070-014-0750-2.
    • (2015) Indian J Otolaryngol Head Neck Surg. , vol.67 , pp. 51-55
    • Amizadeh, M.1    Shamsadini, A.2    Arabzadeh, A.3    Jazayeri, S.4
  • 30
    • 84930379684 scopus 로고    scopus 로고
    • Gastrin may mediate the carcinogenic effect of Helicobacter pylori infection of the stomach
    • PID: 25480404
    • Waldum HL, Hauso O, Sordal OF, Fossmark R. Gastrin may mediate the carcinogenic effect of Helicobacter pylori infection of the stomach. Dig Dis Sci. 2014;. doi:10.1007/s10620-014-3468-9.
    • (2014) Dig Dis Sci
    • Waldum, H.L.1    Hauso, O.2    Sordal, O.F.3    Fossmark, R.4
  • 31
    • 0035856021 scopus 로고    scopus 로고
    • Helicobacter pylori infection and the development of gastric cancer
    • COI: 1:STN:280:DC%2BD3MrgslCqtA%3D%3D, PID: 11556297
    • Uemura N, Okamoto S, Yamamoto S, Matsumura N, Yamaguchi S, Yamakido M, et al. Helicobacter pylori infection and the development of gastric cancer. N Engl J Med. 2001;345(11):784–9. doi:10.1056/NEJMoa001999.
    • (2001) N Engl J Med , vol.345 , Issue.11 , pp. 784-789
    • Uemura, N.1    Okamoto, S.2    Yamamoto, S.3    Matsumura, N.4    Yamaguchi, S.5    Yamakido, M.6
  • 32
    • 78649504564 scopus 로고    scopus 로고
    • Enhanced M1 macrophage polarization in human helicobacter pylori-associated atrophic gastritis and in vaccinated mice
    • PID: 21124899
    • Quiding-Jarbrink M, Raghavan S, Sundquist M. Enhanced M1 macrophage polarization in human helicobacter pylori-associated atrophic gastritis and in vaccinated mice. PLoS One. 2010;5(11):e15018. doi:10.1371/journal.pone.0015018.
    • (2010) PLoS One , vol.5 , Issue.11 , pp. e15018
    • Quiding-Jarbrink, M.1    Raghavan, S.2    Sundquist, M.3
  • 33
    • 84941236558 scopus 로고    scopus 로고
    • Hu CT, Guo LL, Feng N, Zhang L, Zhou N, Ma LL, et al. MIF, secreted by human hepatic sinusoidal endothelial cells, promotes chemotaxis and outgrowth of colorectal cancer in liver prometastasis. Oncotarget. 2015 [Epub ahead of print]
    • Hu CT, Guo LL, Feng N, Zhang L, Zhou N, Ma LL, et al. MIF, secreted by human hepatic sinusoidal endothelial cells, promotes chemotaxis and outgrowth of colorectal cancer in liver prometastasis. Oncotarget. 2015 [Epub ahead of print].
  • 34
    • 84925287252 scopus 로고    scopus 로고
    • Infection with L-form of Helicobacter pylori and expressions of MIF, MMP9 and VEGF in gastric carcinoma
    • COI: 1:CAS:528:DC%2BC2MXntVaktbc%3D, PID: 24589592
    • Ou Y, Kang M, Zhou L, Cheng Z, Tang S, Yu D. Infection with L-form of Helicobacterpylori and expressions of MIF, MMP9 and VEGF in gastric carcinoma. Nan Fang Yi Ke Da Xue Xue Bao. 2014;34(2):180–7.
    • (2014) Nan Fang Yi Ke Da Xue Xue Bao. , vol.34 , Issue.2 , pp. 180-187
    • Ou, Y.1    Kang, M.2    Zhou, L.3    Cheng, Z.4    Tang, S.5    Yu, D.6
  • 35
    • 84915793974 scopus 로고    scopus 로고
    • Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis
    • COI: 1:CAS:528:DC%2BC2cXhvVemtr3E, PID: 25337873
    • Bonapace L, Coissieux MM, Wyckoff J, Mertz KD, Varga Z, Junt T, et al. Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis. Nature. 2014;515(7525):130–3. doi:10.1038/nature13862.
    • (2014) Nature , vol.515 , Issue.7525 , pp. 130-133
    • Bonapace, L.1    Coissieux, M.M.2    Wyckoff, J.3    Mertz, K.D.4    Varga, Z.5    Junt, T.6
  • 36
    • 84921755552 scopus 로고    scopus 로고
    • STATs profiling reveals predominantly-activated STAT3 in cholangiocarcinoma genesis and progression
    • Dokduang H, Techasen A, Namwat N, Khuntikeo N, Pairojkul C, Murakami Y, et al. STATs profiling reveals predominantly-activated STAT3 in cholangiocarcinoma genesis and progression. J Hepato-Biliary-Pancreat Sci. 2014;21(10):767–76. doi:10.1002/jhbp.131.
    • (2014) J Hepato-Biliary-Pancreat Sci , vol.21 , Issue.10 , pp. 767-776
    • Dokduang, H.1    Techasen, A.2    Namwat, N.3    Khuntikeo, N.4    Pairojkul, C.5    Murakami, Y.6
  • 37
    • 79751527661 scopus 로고    scopus 로고
    • Transfused macrophages ameliorate pancreatic and renal injury in murine diabetes mellitus
    • PID: 21311199
    • Zheng D, Wang Y, Cao Q, Lee VW, Zheng G, Sun Y, et al. Transfused macrophages ameliorate pancreatic and renal injury in murine diabetes mellitus. Nephron Exp Nephrol. 2011;118(4):e87–99. doi:10.1159/000321034.
    • (2011) Nephron Exp Nephrol. , vol.118 , Issue.4 , pp. e87-e99
    • Zheng, D.1    Wang, Y.2    Cao, Q.3    Lee, V.W.4    Zheng, G.5    Sun, Y.6
  • 38
    • 84888781899 scopus 로고    scopus 로고
    • Adenosine augments IL-10-induced STAT3 signaling in M2c macrophages
    • PID: 23922379
    • Koscso B, Csoka B, Kokai E, Nemeth ZH, Pacher P, Virag L, et al. Adenosine augments IL-10-induced STAT3 signaling in M2c macrophages. J Leukoc Biol. 2013;94(6):1309–15. doi:10.1189/jlb.0113043.
    • (2013) J Leukoc Biol , vol.94 , Issue.6 , pp. 1309-1315
    • Koscso, B.1    Csoka, B.2    Kokai, E.3    Nemeth, Z.H.4    Pacher, P.5    Virag, L.6
  • 39
    • 84876198050 scopus 로고    scopus 로고
    • Monocytes/macrophages support mammary tumor invasivity by co-secreting lineage-specific EGFR ligands and a STAT3 activator
    • COI: 1:CAS:528:DC%2BC3sXnvFWqtbs%3D, PID: 23597096
    • Vlaicu P, Mertins P, Mayr T, Widschwendter P, Ataseven B, Hogel B, et al. Monocytes/macrophages support mammary tumor invasivity by co-secreting lineage-specific EGFR ligands and a STAT3 activator. BMC Cancer. 2013;13:197. doi:10.1186/1471-2407-13-197.
    • (2013) BMC Cancer , vol.13 , pp. 197
    • Vlaicu, P.1    Mertins, P.2    Mayr, T.3    Widschwendter, P.4    Ataseven, B.5    Hogel, B.6
  • 40
    • 84920854543 scopus 로고    scopus 로고
    • Increased drug resistance in breast cancer by tumor-associated macrophages through IL-10/STAT3/bcl-2 signaling pathway
    • PID: 25572805
    • Yang C, He L, He P, Liu Y, Wang W, He Y, et al. Increased drug resistance in breast cancer by tumor-associated macrophages through IL-10/STAT3/bcl-2 signaling pathway. Med Oncol. 2015;32(2):352. doi:10.1007/s12032-014-0352-6.
    • (2015) Med Oncol , vol.32 , Issue.2 , pp. 352
    • Yang, C.1    He, L.2    He, P.3    Liu, Y.4    Wang, W.5    He, Y.6
  • 41
    • 79960411324 scopus 로고    scopus 로고
    • CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
    • COI: 1:CAS:528:DC%2BC3MXntFKrsb0%3D, PID: 21654748
    • Qian BZ, Li J, Zhang H, Kitamura T, Zhang J, Campion LR, et al. CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis. Nature. 2011;475(7355):222–5. doi:10.1038/nature10138.
    • (2011) Nature , vol.475 , Issue.7355 , pp. 222-225
    • Qian, B.Z.1    Li, J.2    Zhang, H.3    Kitamura, T.4    Zhang, J.5    Campion, L.R.6
  • 42
    • 70350381008 scopus 로고    scopus 로고
    • + stromal cells of monocytic origin to promote breast cancer metastasis to lung and bone
    • COI: 1:CAS:528:DC%2BD1MXht1Cmt7vJ, PID: 19720836
    • + stromal cells of monocytic origin to promote breast cancer metastasis to lung and bone. J Biol Chem. 2009;284(42):29087–96. doi:10.1074/jbc.M109.035899.
    • (2009) J Biol Chem , vol.284 , Issue.42 , pp. 29087-29096
    • Lu, X.1    Kang, Y.2
  • 43
    • 84863756518 scopus 로고    scopus 로고
    • Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway
    • COI: 1:CAS:528:DC%2BC38XhtVSltLjN, PID: 22789541
    • Wolf MJ, Hoos A, Bauer J, Boettcher S, Knust M, Weber A, et al. Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway. Cancer Cell. 2012;22(1):91–105. doi:10.1016/j.ccr.2012.05.023.
    • (2012) Cancer Cell , vol.22 , Issue.1 , pp. 91-105
    • Wolf, M.J.1    Hoos, A.2    Bauer, J.3    Boettcher, S.4    Knust, M.5    Weber, A.6
  • 44
    • 84923052582 scopus 로고    scopus 로고
    • Legumain protein as a potential predictive biomarker for asian patients with breast carcinoma
    • PID: 25605174
    • Wu M, Shao GR, Zhang FX, Wu WX, Xu P, Ruan ZM. Legumain protein as a potential predictive biomarker for asian patients with breast carcinoma. Asian Pac J Cancer Prev. 2014;15(24):10773–7.
    • (2014) Asian Pac J Cancer Prev , vol.15 , Issue.24 , pp. 10773-10777
    • Wu, M.1    Shao, G.R.2    Zhang, F.X.3    Wu, W.X.4    Xu, P.5    Ruan, Z.M.6
  • 45
    • 84904261428 scopus 로고    scopus 로고
    • TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities
    • PID: 24742492
    • D’Costa ZC, Higgins C, Ong CW, Irwin GW, Boyle D, McArt DG, et al. TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities. Oncotarget. 2014;5(6):1609–20.
    • (2014) Oncotarget. , vol.5 , Issue.6 , pp. 1609-1620
    • D’Costa, Z.C.1    Higgins, C.2    Ong, C.W.3    Irwin, G.W.4    Boyle, D.5    McArt, D.G.6
  • 46
    • 33746718151 scopus 로고    scopus 로고
    • Targeting tumor-associated macrophages as a novel strategy against breast cancer
    • COI: 1:CAS:528:DC%2BD28XnvF2mtrk%3D, PID: 16862213
    • Luo Y, Zhou H, Krueger J, Kaplan C, Lee SH, Dolman C, et al. Targeting tumor-associated macrophages as a novel strategy against breast cancer. J Clin Invest. 2006;116(8):2132–41. doi:10.1172/JCI27648.
    • (2006) J Clin Invest. , vol.116 , Issue.8 , pp. 2132-2141
    • Luo, Y.1    Zhou, H.2    Krueger, J.3    Kaplan, C.4    Lee, S.H.5    Dolman, C.6
  • 47
    • 35148874235 scopus 로고    scopus 로고
    • Inflammation and cancer: a double-edged sword
    • COI: 1:CAS:528:DC%2BD2sXht1ais7zM, PID: 17936555
    • Hagemann T, Balkwill F, Lawrence T. Inflammation and cancer: a double-edged sword. Cancer Cell. 2007;12(4):300–1. doi:10.1016/j.ccr.2007.10.005.
    • (2007) Cancer Cell , vol.12 , Issue.4 , pp. 300-301
    • Hagemann, T.1    Balkwill, F.2    Lawrence, T.3
  • 48
    • 84872825787 scopus 로고    scopus 로고
    • Chemokine CXCL16 suppresses liver metastasis of colorectal cancer via augmentation of tumor-infiltrating natural killer T cells in a murine model
    • COI: 1:CAS:528:DC%2BC3sXktFSlt7g%3D, PID: 23242131
    • Kee JY, Ito A, Hojo S, Hashimoto I, Igarashi Y, Tsukada K, et al. Chemokine CXCL16 suppresses liver metastasis of colorectal cancer via augmentation of tumor-infiltrating natural killer T cells in a murine model. Oncol Rep. 2013;29(3):975–82. doi:10.3892/or.2012.2185.
    • (2013) Oncol Rep , vol.29 , Issue.3 , pp. 975-982
    • Kee, J.Y.1    Ito, A.2    Hojo, S.3    Hashimoto, I.4    Igarashi, Y.5    Tsukada, K.6
  • 49
    • 84924671028 scopus 로고    scopus 로고
    • CXCL16 suppresses liver metastasis of colorectal cancer by promoting TNF-alpha-induced apoptosis by tumor-associated macrophages
    • PID: 25495942
    • Kee JY, Ito A, Hojo S, Hashimoto I, Igarashi Y, Tsuneyama K, et al. CXCL16 suppresses liver metastasis of colorectal cancer by promoting TNF-alpha-induced apoptosis by tumor-associated macrophages. BMC Cancer. 2014;14:949. doi:10.1186/1471-2407-14-949.
    • (2014) BMC Cancer , vol.14 , pp. 949
    • Kee, J.Y.1    Ito, A.2    Hojo, S.3    Hashimoto, I.4    Igarashi, Y.5    Tsuneyama, K.6
  • 50
    • 77955410185 scopus 로고    scopus 로고
    • Tumor associated macrophages protect colon cancer cells from TRAIL-induced apoptosis through IL-1beta-dependent stabilization of Snail in tumor cells
    • PID: 20661477
    • Kaler P, Galea V, Augenlicht L, Klampfer L. Tumor associated macrophages protect colon cancer cells from TRAIL-induced apoptosis through IL-1beta-dependent stabilization of Snail in tumor cells. PLoS One. 2010;5(7):e11700. doi:10.1371/journal.pone.0011700.
    • (2010) PLoS One , vol.5 , Issue.7 , pp. e11700
    • Kaler, P.1    Galea, V.2    Augenlicht, L.3    Klampfer, L.4
  • 51
    • 84929142910 scopus 로고    scopus 로고
    • Urokinase-type plasminogen activator receptor (uPAR) on tumor-associated macrophages is a marker of poor prognosis in colorectal cancer
    • COI: 1:CAS:528:DC%2BC2cXht12gur3K, PID: 24889870
    • Illemann M, Laerum OD, Hasselby JP, Thurison T, Hoyer-Hansen G, Nielsen HJ, et al. Urokinase-type plasminogen activator receptor (uPAR) on tumor-associated macrophages is a marker of poor prognosis in colorectal cancer. Cancer Med. 2014;3(4):855–64. doi:10.1002/cam4.242.
    • (2014) Cancer Med. , vol.3 , Issue.4 , pp. 855-864
    • Illemann, M.1    Laerum, O.D.2    Hasselby, J.P.3    Thurison, T.4    Hoyer-Hansen, G.5    Nielsen, H.J.6
  • 52
    • 84928231190 scopus 로고    scopus 로고
    • Expression of inhibitory regulators of innate immunity in patients with active tuberculosis
    • PID: 25887604
    • Blok DC, Kager LM, Hoogendijk AJ, Lede IO, Rahman W, Afroz R, et al. Expression of inhibitory regulators of innate immunity in patients with active tuberculosis. BMC Infect Dis. 2015;15(1):98. doi:10.1186/s12879-015-0833-z.
    • (2015) BMC Infect Dis , vol.15 , Issue.1 , pp. 98
    • Blok, D.C.1    Kager, L.M.2    Hoogendijk, A.J.3    Lede, I.O.4    Rahman, W.5    Afroz, R.6
  • 53
    • 40849118333 scopus 로고    scopus 로고
    • High tumour islet macrophage infiltration correlates with improved patient survival but not with EGFR mutations, gene copy number or protein expression in resected non-small cell lung cancer
    • COI: 1:CAS:528:DC%2BD1cXjtlGktLk%3D, PID: 18283317
    • Kim DW, Min HS, Lee KH, Kim YJ, Oh DY, Jeon YK, et al. High tumour islet macrophage infiltration correlates with improved patient survival but not with EGFR mutations, gene copy number or protein expression in resected non-small cell lung cancer. Br J Cancer. 2008;98(6):1118–24. doi:10.1038/sj.bjc.6604256.
    • (2008) Br J Cancer , vol.98 , Issue.6 , pp. 1118-1124
    • Kim, D.W.1    Min, H.S.2    Lee, K.H.3    Kim, Y.J.4    Oh, D.Y.5    Jeon, Y.K.6
  • 54
    • 32644466544 scopus 로고    scopus 로고
    • Macrophage and mast-cell invasion of tumor cell islets confers a marked survival advantage in non-small-cell lung cancer
    • Welsh TJ, Green RH, Richardson D, Waller DA, O’Byrne KJ, Bradding P. Macrophage and mast-cell invasion of tumor cell islets confers a marked survival advantage in non-small-cell lung cancer. J Clin Oncol Off J Am Soc Clin Oncol. 2005;23(35):8959–67. doi:10.1200/JCO.2005.01.4910.
    • (2005) J Clin Oncol Off J Am Soc Clin Oncol , vol.23 , Issue.35 , pp. 8959-8967
    • Welsh, T.J.1    Green, R.H.2    Richardson, D.3    Waller, D.A.4    O’Byrne, K.J.5    Bradding, P.6
  • 55
    • 84883712769 scopus 로고    scopus 로고
    • Lung tumor microenvironment induces specific gene expression signature in intratumoral NK cells
    • PID: 23382731
    • Gillard-Bocquet M, Caer C, Cagnard N, Crozet L, Perez M, Fridman WH, et al. Lung tumor microenvironment induces specific gene expression signature in intratumoral NK cells. Front Immunol. 2013;4:19. doi:10.3389/fimmu.2013.00019.
    • (2013) Front Immunol , vol.4 , pp. 19
    • Gillard-Bocquet, M.1    Caer, C.2    Cagnard, N.3    Crozet, L.4    Perez, M.5    Fridman, W.H.6
  • 56
    • 84922900718 scopus 로고    scopus 로고
    • Macrophage and cancer cell cross-talk via CCR2 and CX3CR1 is a fundamental mechanism driving lung cancer
    • COI: 1:CAS:528:DC%2BC2MXjvFGisLs%3D, PID: 25536148
    • Schmall A, Al-Tamari HM, Herold S, Kampschulte M, Weigert A, Wietelmann A, et al. Macrophage and cancer cell cross-talk via CCR2 and CX3CR1 is a fundamental mechanism driving lung cancer. Am J Respir Crit Care Med. 2015;191(4):437–47. doi:10.1164/rccm.201406-1137OC.
    • (2015) Am J Respir Crit Care Med , vol.191 , Issue.4 , pp. 437-447
    • Schmall, A.1    Al-Tamari, H.M.2    Herold, S.3    Kampschulte, M.4    Weigert, A.5    Wietelmann, A.6
  • 57
    • 84919329262 scopus 로고    scopus 로고
    • Depletion of tumor-associated macrophages slows the growth of chemically induced mouse lung adenocarcinomas
    • PID: 25505466
    • Fritz JM, Tennis MA, Orlicky DJ, Lin H, Ju C, Redente EF, et al. Depletion of tumor-associated macrophages slows the growth of chemically induced mouse lung adenocarcinomas. Front Immunol. 2014;5:587. doi:10.3389/fimmu.2014.00587.
    • (2014) Front Immunol , vol.5 , pp. 587
    • Fritz, J.M.1    Tennis, M.A.2    Orlicky, D.J.3    Lin, H.4    Ju, C.5    Redente, E.F.6
  • 58
    • 84881099843 scopus 로고    scopus 로고
    • Tumor associated macrophage expressing CD204 is associated with tumor aggressiveness of esophageal squamous cell carcinoma
    • COI: 1:CAS:528:DC%2BC3sXhtF2qsb%2FL, PID: 23648122
    • Shigeoka M, Urakawa N, Nakamura T, Nishio M, Watajima T, Kuroda D, et al. Tumor associated macrophage expressing CD204 is associated with tumor aggressiveness of esophageal squamous cell carcinoma. Cancer Sci. 2013;104(8):1112–9. doi:10.1111/cas.12188.
    • (2013) Cancer Sci , vol.104 , Issue.8 , pp. 1112-1119
    • Shigeoka, M.1    Urakawa, N.2    Nakamura, T.3    Nishio, M.4    Watajima, T.5    Kuroda, D.6
  • 59
    • 84979853631 scopus 로고    scopus 로고
    • Cyr61 promotes CD204 expression and the migration of macrophages via MEK/ERK pathway in esophageal squamous cell carcinoma
    • PID: 25620088
    • Shigeoka M, Urakawa N, Nishio M, Takase N, Utsunomiya S, Akiyama H, et al. Cyr61 promotes CD204 expression and the migration of macrophages via MEK/ERK pathway in esophageal squamous cell carcinoma. Cancer Med. 2015;. doi:10.1002/cam4.401.
    • (2015) Cancer Med
    • Shigeoka, M.1    Urakawa, N.2    Nishio, M.3    Takase, N.4    Utsunomiya, S.5    Akiyama, H.6
  • 60
    • 84922843084 scopus 로고    scopus 로고
    • Distribution and clinical significance of tumour-associated macrophages in pancreatic ductal adenocarcinoma: a retrospective analysis in China
    • COI: 1:STN:280:DC%2BC2MrlvVyitA%3D%3D, PID: 25684992
    • Chen SJ, Zhang QB, Zeng LJ, Lian GD, Li JJ, Qian CC, et al. Distribution and clinical significance of tumour-associated macrophages in pancreatic ductal adenocarcinoma: a retrospective analysis in China. Curr Oncol. 2015;22(1):e11–9. doi:10.3747/co.22.2150.
    • (2015) Curr Oncol. , vol.22 , Issue.1 , pp. e11-e19
    • Chen, S.J.1    Zhang, Q.B.2    Zeng, L.J.3    Lian, G.D.4    Li, J.J.5    Qian, C.C.6
  • 61
    • 84922799330 scopus 로고    scopus 로고
    • Interaction between pancreatic cancer cells and tumor-associated macrophages promotes the invasion of pancreatic cancer cells and the differentiation and migration of macrophages
    • COI: 1:CAS:528:DC%2BC2cXitFynsrnJ, PID: 25557640
    • Meng F, Li C, Li W, Gao Z, Guo K, Song S. Interaction between pancreatic cancer cells and tumor-associated macrophages promotes the invasion of pancreatic cancer cells and the differentiation and migration of macrophages. IUBMB Life. 2014;66(12):835–46. doi:10.1002/iub.1336.
    • (2014) IUBMB Life , vol.66 , Issue.12 , pp. 835-846
    • Meng, F.1    Li, C.2    Li, W.3    Gao, Z.4    Guo, K.5    Song, S.6
  • 62
    • 84904054241 scopus 로고    scopus 로고
    • Tumour-educated macrophages display a mixed polarisation and enhance pancreatic cancer cell invasion
    • COI: 1:CAS:528:DC%2BC2cXkvF2nsLk%3D, PID: 24662521
    • Karnevi E, Andersson R, Rosendahl AH. Tumour-educated macrophages display a mixed polarisation and enhance pancreatic cancer cell invasion. Immunol Cell Biol. 2014;92(6):543–52. doi:10.1038/icb.2014.22.
    • (2014) Immunol Cell Biol , vol.92 , Issue.6 , pp. 543-552
    • Karnevi, E.1    Andersson, R.2    Rosendahl, A.H.3
  • 63
    • 84902269793 scopus 로고    scopus 로고
    • Prognostic impact of M2 macrophages at neural invasion in patients with invasive ductal carcinoma of the pancreas
    • COI: 1:CAS:528:DC%2BC2cXotFyhs7Y%3D, PID: 24835032
    • Sugimoto M, Mitsunaga S, Yoshikawa K, Kato Y, Gotohda N, Takahashi S, et al. Prognostic impact of M2 macrophages at neural invasion in patients with invasive ductal carcinoma of the pancreas. Eur J Cancer. 2014;50(11):1900–8. doi:10.1016/j.ejca.2014.04.010.
    • (2014) Eur J Cancer , vol.50 , Issue.11 , pp. 1900-1908
    • Sugimoto, M.1    Mitsunaga, S.2    Yoshikawa, K.3    Kato, Y.4    Gotohda, N.5    Takahashi, S.6
  • 64
    • 84922395352 scopus 로고    scopus 로고
    • Hermano E, Meirovitz A, Meir K, Nussbaum G, Appelbaum L, Peretz T, et al. Macrophage polarization in pancreatic carcinoma: role of heparanase enzyme. J Natl Cancer Inst. 2014;106(12)
    • Hermano E, Meirovitz A, Meir K, Nussbaum G, Appelbaum L, Peretz T, et al. Macrophage polarization in pancreatic carcinoma: role of heparanase enzyme. J Natl Cancer Inst. 2014;106(12). doi:10.1093/jnci/dju332.
  • 65
    • 84906791750 scopus 로고    scopus 로고
    • Coexpression of CD44-positive/CD133-positive cancer stem cells and CD204-positive tumor-associated macrophages is a predictor of survival in pancreatic ductal adenocarcinoma
    • COI: 1:CAS:528:DC%2BC2cXhsVWlurrP, PID: 24839953
    • Hou YC, Chao YJ, Tung HL, Wang HC, Shan YS. Coexpression of CD44-positive/CD133-positive cancer stem cells and CD204-positive tumor-associated macrophages is a predictor of survival in pancreatic ductal adenocarcinoma. Cancer. 2014;120(17):2766–77. doi:10.1002/cncr.28774.
    • (2014) Cancer , vol.120 , Issue.17 , pp. 2766-2777
    • Hou, Y.C.1    Chao, Y.J.2    Tung, H.L.3    Wang, H.C.4    Shan, Y.S.5
  • 66
    • 84891946295 scopus 로고    scopus 로고
    • High MUC2 expression in ovarian cancer is inversely associated with the M1/M2 ratio of tumor-associated macrophages and patient survival time
    • PID: 24324582
    • He YF, Zhang MY, Wu X, Sun XJ, Xu T, He QZ, et al. High MUC2 expression in ovarian cancer is inversely associated with the M1/M2 ratio of tumor-associated macrophages and patient survival time. PLoS One. 2013;8(12):e79769. doi:10.1371/journal.pone.0079769.
    • (2013) PLoS One , vol.8 , Issue.12 , pp. e79769
    • He, Y.F.1    Zhang, M.Y.2    Wu, X.3    Sun, X.J.4    Xu, T.5    He, Q.Z.6
  • 67
    • 84958226119 scopus 로고    scopus 로고
    • Armaiz-Pena GN, Gonzalez-Villasana V, Nagaraja AS, Rodriguez-Aguayo C, Sadaoui NC, Stone RL, et al. Adrenergic regulation of monocyte chemotactic protein 1 leads to enhanced macrophage recruitment and ovarian carcinoma growth. Oncotarget. 2014 [Epub ahead of print]
    • Armaiz-Pena GN, Gonzalez-Villasana V, Nagaraja AS, Rodriguez-Aguayo C, Sadaoui NC, Stone RL, et al. Adrenergic regulation of monocyte chemotactic protein 1 leads to enhanced macrophage recruitment and ovarian carcinoma growth. Oncotarget. 2014 [Epub ahead of print].
  • 68
    • 84890357888 scopus 로고    scopus 로고
    • Expression of the homeobox gene HOXA9 in ovarian cancer induces peritoneal macrophages to acquire an M2 tumor-promoting phenotype
    • COI: 1:CAS:528:DC%2BC3sXitVSgsL%2FO, PID: 24332016
    • Ko SY, Ladanyi A, Lengyel E, Naora H. Expression of the homeobox gene HOXA9 in ovarian cancer induces peritoneal macrophages to acquire an M2 tumor-promoting phenotype. Am J Pathol. 2014;184(1):271–81. doi:10.1016/j.ajpath.2013.09.017.
    • (2014) Am J Pathol , vol.184 , Issue.1 , pp. 271-281
    • Ko, S.Y.1    Ladanyi, A.2    Lengyel, E.3    Naora, H.4
  • 69
    • 84893655060 scopus 로고    scopus 로고
    • A high M1/M2 ratio of tumor-associated macrophages is associated with extended survival in ovarian cancer patients
    • PID: 24507759
    • Zhang M, He Y, Sun X, Li Q, Wang W, Zhao A, et al. A high M1/M2 ratio of tumor-associated macrophages is associated with extended survival in ovarian cancer patients. J Ovarian Res. 2014;7:19. doi:10.1186/1757-2215-7-19.
    • (2014) J Ovarian Res. , vol.7 , pp. 19
    • Zhang, M.1    He, Y.2    Sun, X.3    Li, Q.4    Wang, W.5    Zhao, A.6
  • 70
    • 84925018155 scopus 로고    scopus 로고
    • BRAF and MEK inhibition in melanoma
    • COI: 1:CAS:528:DC%2BC2MXkvVOrt70%3D, PID: 25648338
    • Dossett LA, Kudchadkar RR, Zager JS. BRAF and MEK inhibition in melanoma. Expert Opin Drug Saf. 2015;14(4):559–70.
    • (2015) Expert Opin Drug Saf. , vol.14 , Issue.4 , pp. 559-570
    • Dossett, L.A.1    Kudchadkar, R.R.2    Zager, J.S.3
  • 71
    • 84927594692 scopus 로고    scopus 로고
    • BRAF inhibition stimulates melanoma-associated macrophages to drive tumor growth
    • Wang T, Xiao M, Ge Y, Krepler C, Belser E, Lopez-Coral A, et al. BRAF inhibition stimulates melanoma-associated macrophages to drive tumor growth. Clin Cancer Res. 2015;. doi:10.1158/1078-0432.CCR-14-1554.
    • (2015) Clin Cancer Res
    • Wang, T.1    Xiao, M.2    Ge, Y.3    Krepler, C.4    Belser, E.5    Lopez-Coral, A.6
  • 72
    • 84920023709 scopus 로고    scopus 로고
    • Melanoma-initiating cells exploit M2 macrophage TGFbeta and arginase pathway for survival and proliferation
    • PID: 25294815
    • Tham M, Tan KW, Keeble J, Wang X, Hubert S, Barron L, et al. Melanoma-initiating cells exploit M2 macrophage TGFbeta and arginase pathway for survival and proliferation. Oncotarget. 2014;5(23):12027–42.
    • (2014) Oncotarget. , vol.5 , Issue.23 , pp. 12027-12042
    • Tham, M.1    Tan, K.W.2    Keeble, J.3    Wang, X.4    Hubert, S.5    Barron, L.6
  • 73
    • 84922061259 scopus 로고    scopus 로고
    • Tumor-associated macrophages induce lymphangiogenesis in cervical cancer via interaction with tumor cells
    • COI: 1:CAS:528:DC%2BC2cXhvVSjs7%2FN, PID: 24698523
    • Ding H, Cai J, Mao M, Fang Y, Huang Z, Jia J, et al. Tumor-associated macrophages induce lymphangiogenesis in cervical cancer via interaction with tumor cells. APMIS. 2014;122(11):1059–69. doi:10.1111/apm.12257.
    • (2014) APMIS , vol.122 , Issue.11 , pp. 1059-1069
    • Ding, H.1    Cai, J.2    Mao, M.3    Fang, Y.4    Huang, Z.5    Jia, J.6
  • 74
    • 84894520967 scopus 로고    scopus 로고
    • CSF1R inhibition delays cervical and mammary tumor growth in murine models by attenuating the turnover of tumor-associated macrophages and enhancing infiltration by CD8 T cells
    • PID: 24498562
    • Strachan DC, Ruffell B, Oei Y, Bissell MJ, Coussens LM, Pryer N, et al. CSF1R inhibition delays cervical and mammary tumor growth in murine models by attenuating the turnover of tumor-associated macrophages and enhancing infiltration by CD8 T cells. Oncoimmunology. 2013;2(12):e26968. doi:10.4161/onci.26968.
    • (2013) Oncoimmunology. , vol.2 , Issue.12 , pp. e26968
    • Strachan, D.C.1    Ruffell, B.2    Oei, Y.3    Bissell, M.J.4    Coussens, L.M.5    Pryer, N.6
  • 75
    • 84876998346 scopus 로고    scopus 로고
    • Chemotherapy alters monocyte differentiation to favor generation of cancer-supporting M2 macrophages in the tumor microenvironment
    • COI: 1:CAS:528:DC%2BC3sXlvFOrtbw%3D, PID: 23436796
    • Dijkgraaf EM, Heusinkveld M, Tummers B, Vogelpoel LT, Goedemans R, Jha V, et al. Chemotherapy alters monocyte differentiation to favor generation of cancer-supporting M2 macrophages in the tumor microenvironment. Cancer Res. 2013;73(8):2480–92. doi:10.1158/0008-5472.CAN-12-3542.
    • (2013) Cancer Res , vol.73 , Issue.8 , pp. 2480-2492
    • Dijkgraaf, E.M.1    Heusinkveld, M.2    Tummers, B.3    Vogelpoel, L.T.4    Goedemans, R.5    Jha, V.6
  • 76
    • 48349102876 scopus 로고    scopus 로고
    • Macrophage polarization in tumour progression
    • COI: 1:CAS:528:DC%2BD1cXpsVGmsLo%3D, PID: 18467122
    • Sica A, Larghi P, Mancino A, Rubino L, Porta C, Totaro MG, et al. Macrophage polarization in tumour progression. Semin Cancer Biol. 2008;18(5):349–55. doi:10.1016/j.semcancer.2008.03.004.
    • (2008) Semin Cancer Biol , vol.18 , Issue.5 , pp. 349-355
    • Sica, A.1    Larghi, P.2    Mancino, A.3    Rubino, L.4    Porta, C.5    Totaro, M.G.6
  • 77
    • 33645991795 scopus 로고    scopus 로고
    • Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy
    • COI: 1:CAS:528:DC%2BD28Xjs1Grt78%3D, PID: 16520032
    • Sica A, Schioppa T, Mantovani A, Allavena P. Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy. Eur J Cancer. 2006;42(6):717–27. doi:10.1016/j.ejca.2006.01.003.
    • (2006) Eur J Cancer , vol.42 , Issue.6 , pp. 717-727
    • Sica, A.1    Schioppa, T.2    Mantovani, A.3    Allavena, P.4
  • 78
    • 65349092794 scopus 로고    scopus 로고
    • Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion
    • COI: 1:CAS:528:DC%2BD1MXmvVGitrs%3D, PID: 19411070
    • Wu Y, Deng J, Rychahou PG, Qiu S, Evers BM, Zhou BP. Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion. Cancer Cell. 2009;15(5):416–28. doi:10.1016/j.ccr.2009.03.016.
    • (2009) Cancer Cell , vol.15 , Issue.5 , pp. 416-428
    • Wu, Y.1    Deng, J.2    Rychahou, P.G.3    Qiu, S.4    Evers, B.M.5    Zhou, B.P.6


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