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Volumn 21, Issue 10, 2014, Pages 767-776

STATs profiling reveals predominantly-activated STAT3 in cholangiocarcinoma genesis and progression

Author keywords

Cholangiocarcinoma; Inflammation; Signal transducer and activator of transcription 3

Indexed keywords

LIPOPOLYSACCHARIDE; STAT1 PROTEIN; STAT2 PROTEIN; STAT3 PROTEIN; STAT4 PROTEIN; STAT5A PROTEIN; STAT5B PROTEIN; STAT6 PROTEIN; STAT PROTEIN; TUMOR MARKER;

EID: 84921755552     PISSN: 18686974     EISSN: 18686982     Source Type: Journal    
DOI: 10.1002/jhbp.131     Document Type: Conference Paper
Times cited : (49)

References (48)
  • 1
    • 0025165365 scopus 로고
    • A high frequency of hepatobiliary disease and suspected cholangiocarcinoma associated with heavy Opisthorchis viverrini infection in a small community in north-east Thailand
    • Elkins DB, Haswell-Elkins MR, Mairiang E, Mairiang P, Sithithaworn P, Kaewkes S, et al. A high frequency of hepatobiliary disease and suspected cholangiocarcinoma associated with heavy Opisthorchis viverrini infection in a small community in north-east Thailand. Trans R Soc Trop Med Hyg. 1990; 84: 715-719.
    • (1990) Trans R Soc Trop Med Hyg , vol.84 , pp. 715-719
    • Elkins, D.B.1    Haswell-Elkins, M.R.2    Mairiang, E.3    Mairiang, P.4    Sithithaworn, P.5    Kaewkes, S.6
  • 2
    • 0029783816 scopus 로고    scopus 로고
    • Cross-sectional patterns of hepatobiliary abnormalities and possible precursor conditions of cholangiocarcinoma associated with Opisthorchis viverrini infection in humans
    • Elkins DB, Mairiang E, Sithithaworn P, Mairiang P, Chaiyakum J, Chamadol N, et al. Cross-sectional patterns of hepatobiliary abnormalities and possible precursor conditions of cholangiocarcinoma associated with Opisthorchis viverrini infection in humans. Am J Trop Med Hyg. 1996; 55: 295-301.
    • (1996) Am J Trop Med Hyg , vol.55 , pp. 295-301
    • Elkins, D.B.1    Mairiang, E.2    Sithithaworn, P.3    Mairiang, P.4    Chaiyakum, J.5    Chamadol, N.6
  • 3
    • 0027986844 scopus 로고
    • Cross-sectional study of Opisthorchis viverrini infection and cholangiocarcinoma in communities within a high-risk area in northeast Thailand
    • Haswell-Elkins MR, Mairiang E, Mairiang P, Chaiyakum J, Chamadol N, Loapaiboon V, et al. Cross-sectional study of Opisthorchis viverrini infection and cholangiocarcinoma in communities within a high-risk area in northeast Thailand. Int J Cancer. 1994; 59: 505-509.
    • (1994) Int J Cancer , vol.59 , pp. 505-509
    • Haswell-Elkins, M.R.1    Mairiang, E.2    Mairiang, P.3    Chaiyakum, J.4    Chamadol, N.5    Loapaiboon, V.6
  • 4
    • 0032777036 scopus 로고    scopus 로고
    • Mechanisms of biliary carcinogenesis: A pathogenetic multi-stage cascade towards cholangiocarcinoma
    • Holzinger F, Z'Graggen K, Buchler MW,. Mechanisms of biliary carcinogenesis: a pathogenetic multi-stage cascade towards cholangiocarcinoma. Ann Oncol. 1999; 10 (Suppl 4): 122-126.
    • (1999) Ann Oncol , vol.10 , pp. 122-126
    • Holzinger, F.1    Z'Graggen, K.2    Buchler, M.W.3
  • 7
    • 2942615272 scopus 로고    scopus 로고
    • The epidemiology of cholangiocarcinoma
    • Shaib Y, El-Serag HB,. The epidemiology of cholangiocarcinoma. Semin Liver Dis. 2004; 24: 115-125.
    • (2004) Semin Liver Dis , vol.24 , pp. 115-125
    • Shaib, Y.1    El-Serag, H.B.2
  • 8
    • 84856218714 scopus 로고    scopus 로고
    • Liver fluke-induced hepatic oxysterols stimulate DNA damage and apoptosis in cultured human cholangiocytes
    • Jusakul A, Loilome W, Namwat N, Haigh WG, Kuver R, Dechakhamphu S, et al. Liver fluke-induced hepatic oxysterols stimulate DNA damage and apoptosis in cultured human cholangiocytes. Mutat Res. 2012; 731: 48-57.
    • (2012) Mutat Res , vol.731 , pp. 48-57
    • Jusakul, A.1    Loilome, W.2    Namwat, N.3    Haigh, W.G.4    Kuver, R.5    Dechakhamphu, S.6
  • 9
    • 5644274281 scopus 로고    scopus 로고
    • Mechanism of NO-mediated oxidative and nitrative DNA damage in hamsters infected with Opisthorchis viverrini: A model of inflammation-mediated carcinogenesis
    • Pinlaor S, Hiraku Y, Ma N, Yongvanit P, Semba R, Oikawa S, et al. Mechanism of NO-mediated oxidative and nitrative DNA damage in hamsters infected with Opisthorchis viverrini: a model of inflammation-mediated carcinogenesis. Nitric Oxide. 2004; 11: 175-183.
    • (2004) Nitric Oxide , vol.11 , pp. 175-183
    • Pinlaor, S.1    Hiraku, Y.2    Ma, N.3    Yongvanit, P.4    Semba, R.5    Oikawa, S.6
  • 11
    • 41549096267 scopus 로고    scopus 로고
    • Urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine in patients with parasite infection and effect of antiparasitic drug in relation to cholangiocarcinogenesis
    • Thanan R, Murata M, Pinlaor S, Sithithaworn P, Khuntikeo N, Tangkanakul W, et al. Urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine in patients with parasite infection and effect of antiparasitic drug in relation to cholangiocarcinogenesis. Cancer Epidemiol Biomarkers Prev. 2008; 17: 518-524.
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , pp. 518-524
    • Thanan, R.1    Murata, M.2    Pinlaor, S.3    Sithithaworn, P.4    Khuntikeo, N.5    Tangkanakul, W.6
  • 12
    • 82655162242 scopus 로고    scopus 로고
    • Oxidative and nitrative DNA damage: Key events in opisthorchiasis-induced carcinogenesis
    • Yongvanit P, Pinlaor S, Bartsch H,. Oxidative and nitrative DNA damage: key events in opisthorchiasis-induced carcinogenesis. Parasitol Int. 2012; 61: 130-135.
    • (2012) Parasitol Int , vol.61 , pp. 130-135
    • Yongvanit, P.1    Pinlaor, S.2    Bartsch, H.3
  • 13
    • 79955377885 scopus 로고    scopus 로고
    • PRKAR1A is overexpressed and represents a possible therapeutic target in human cholangiocarcinoma
    • Loilome W, Juntana S, Namwat N, Bhudhisawasdi V, Puapairoj A, Sripa B, et al. PRKAR1A is overexpressed and represents a possible therapeutic target in human cholangiocarcinoma. Int J Cancer. 2011; 129: 34-44.
    • (2011) Int J Cancer , vol.129 , pp. 34-44
    • Loilome, W.1    Juntana, S.2    Namwat, N.3    Bhudhisawasdi, V.4    Puapairoj, A.5    Sripa, B.6
  • 14
    • 33646743628 scopus 로고    scopus 로고
    • Altered gene expression in Opisthorchis viverrini-associated cholangiocarcinoma in hamster model
    • Loilome W, Yongvanit P, Wongkham C, Tepsiri N, Sripa B, Sithithaworn P, et al. Altered gene expression in Opisthorchis viverrini-associated cholangiocarcinoma in hamster model. Mol Carcinog. 2006; 45: 279-287.
    • (2006) Mol Carcinog , vol.45 , pp. 279-287
    • Loilome, W.1    Yongvanit, P.2    Wongkham, C.3    Tepsiri, N.4    Sripa, B.5    Sithithaworn, P.6
  • 15
    • 77949609590 scopus 로고    scopus 로고
    • Myristoylated alanine-rich C kinase substrate phosphorylation promotes cholangiocarcinoma cell migration and metastasis via the protein kinase C-dependent pathway
    • Techasen A, Loilome W, Namwat N, Takahashi E, Sugihara E, Puapairoj A, et al. Myristoylated alanine-rich C kinase substrate phosphorylation promotes cholangiocarcinoma cell migration and metastasis via the protein kinase C-dependent pathway. Cancer Sci. 2010; 101: 658-665.
    • (2010) Cancer Sci , vol.101 , pp. 658-665
    • Techasen, A.1    Loilome, W.2    Namwat, N.3    Takahashi, E.4    Sugihara, E.5    Puapairoj, A.6
  • 16
    • 84891494820 scopus 로고    scopus 로고
    • Survey of activated kinase proteins reveals potential targets for cholangiocarcinoma treatment
    • Dokduang H, Juntana S, Techasen A, Namwat N, Yongvanit P, Khuntikeo N, et al. Survey of activated kinase proteins reveals potential targets for cholangiocarcinoma treatment. Tumour Biol. 2013; 34: 3519-3528.
    • (2013) Tumour Biol , vol.34 , pp. 3519-3528
    • Dokduang, H.1    Juntana, S.2    Techasen, A.3    Namwat, N.4    Yongvanit, P.5    Khuntikeo, N.6
  • 17
    • 0034657336 scopus 로고    scopus 로고
    • The role of STATs in transcriptional control and their impact on cellular function
    • Bromberg J, Darnell JE, Jr,. The role of STATs in transcriptional control and their impact on cellular function. Oncogene. 2000; 19: 2468-2473.
    • (2000) Oncogene , vol.19 , pp. 2468-2473
    • Bromberg, J.1    Darnell, Jr.J.E.2
  • 18
    • 0032191341 scopus 로고    scopus 로고
    • STAT structure and function in signaling
    • Hoey T, Schindler U,. STAT structure and function in signaling. Curr Opin Genet Dev. 1998; 8: 582-587.
    • (1998) Curr Opin Genet Dev , vol.8 , pp. 582-587
    • Hoey, T.1    Schindler, U.2
  • 19
    • 0034306290 scopus 로고    scopus 로고
    • STAT proteins and transcriptional responses to extracellular signals
    • Horvath CM,. STAT proteins and transcriptional responses to extracellular signals. Trends Biochem Sci. 2000; 25: 496-502.
    • (2000) Trends Biochem Sci , vol.25 , pp. 496-502
    • Horvath, C.M.1
  • 20
    • 0036251154 scopus 로고    scopus 로고
    • Stat proteins and oncogenesis
    • Bromberg J,. Stat proteins and oncogenesis. J Clin Invest. 2002; 109: 1139-1142.
    • (2002) J Clin Invest , vol.109 , pp. 1139-1142
    • Bromberg, J.1
  • 21
    • 38349063045 scopus 로고    scopus 로고
    • JAK-STAT pathway in carcinogenesis: Is it relevant to cholangiocarcinoma progression?
    • Smirnova OV, Ostroukhova TY, Bogorad RL,. JAK-STAT pathway in carcinogenesis: is it relevant to cholangiocarcinoma progression? World J Gastroenterol. 2007; 13: 6478-6491.
    • (2007) World J Gastroenterol , vol.13 , pp. 6478-6491
    • Smirnova, O.V.1    Ostroukhova, T.Y.2    Bogorad, R.L.3
  • 22
    • 0034722896 scopus 로고    scopus 로고
    • STAT proteins: Novel molecular targets for cancer drug discovery
    • Turkson J, Jove R,. STAT proteins: novel molecular targets for cancer drug discovery. Oncogene. 2000; 19: 6613-6626.
    • (2000) Oncogene , vol.19 , pp. 6613-6626
    • Turkson, J.1    Jove, R.2
  • 23
    • 84874100938 scopus 로고    scopus 로고
    • Cytokines released from activated human macrophages induce epithelial mesenchymal transition markers of cholangiocarcinoma cells
    • Techasen A, Loilome W, Namwat N, Dokduang H, Jongthawin J, Yongvanit P,. Cytokines released from activated human macrophages induce epithelial mesenchymal transition markers of cholangiocarcinoma cells. Asian Pac J Cancer Prev. 2012; 13 (Suppl): 115-118.
    • (2012) Asian Pac J Cancer Prev , vol.13 , pp. 115-118
    • Techasen, A.1    Loilome, W.2    Namwat, N.3    Dokduang, H.4    Jongthawin, J.5    Yongvanit, P.6
  • 24
    • 84888385562 scopus 로고    scopus 로고
    • Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers
    • Chan-On W, Nairismagi ML, Ong CK, Lim WK, Dima S, Pairojkul C, et al. Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers. Nat Genet. 2013; 45: 1474-1478.
    • (2013) Nat Genet , vol.45 , pp. 1474-1478
    • Chan-On, W.1    Nairismagi, M.L.2    Ong, C.K.3    Lim, W.K.4    Dima, S.5    Pairojkul, C.6
  • 25
    • 0034835564 scopus 로고    scopus 로고
    • Altered expression of beta-catenin without genetic mutation in intrahepatic cholangiocarcinoma
    • Sugimachi K, Taguchi K, Aishima S, Tanaka S, Shimada M, Kajiyama K, et al. Altered expression of beta-catenin without genetic mutation in intrahepatic cholangiocarcinoma. Mod Pathol. 2001; 14: 900-905.
    • (2001) Mod Pathol , vol.14 , pp. 900-905
    • Sugimachi, K.1    Taguchi, K.2    Aishima, S.3    Tanaka, S.4    Shimada, M.5    Kajiyama, K.6
  • 26
    • 70349563344 scopus 로고    scopus 로고
    • Advances in diagnosis, treatment and palliation of cholangiocarcinoma: 1990-2009
    • Aljiffry M, Walsh MJ, Molinari M,. Advances in diagnosis, treatment and palliation of cholangiocarcinoma: 1990-2009. World J Gastroenterol. 2009; 15: 4240-4262.
    • (2009) World J Gastroenterol , vol.15 , pp. 4240-4262
    • Aljiffry, M.1    Walsh, M.J.2    Molinari, M.3
  • 27
    • 84876081954 scopus 로고    scopus 로고
    • STAT3 expression correlates with prognosis of thymic epithelial tumors
    • Li C, Wang Z, Liu Y, Wang P, Zhang R,. STAT3 expression correlates with prognosis of thymic epithelial tumors. J Cardiothorac Surg. 2013; 8: 92-98.
    • (2013) J Cardiothorac Surg , vol.8 , pp. 92-98
    • Li, C.1    Wang, Z.2    Liu, Y.3    Wang, P.4    Zhang, R.5
  • 28
    • 84858793335 scopus 로고    scopus 로고
    • Risk factors for cholangiocarcinoma in high-risk area of Thailand: Role of lifestyle, diet and methylenetetrahydrofolate reductase polymorphisms
    • Songserm N, Promthet S, Sithithaworn P, Pientong C, Ekalaksananan T, Chopjitt P, et al. Risk factors for cholangiocarcinoma in high-risk area of Thailand: role of lifestyle, diet and methylenetetrahydrofolate reductase polymorphisms. Cancer Epidemiol. 2012; 36: e89-94.
    • (2012) Cancer Epidemiol , vol.36 , pp. e89-e94
    • Songserm, N.1    Promthet, S.2    Sithithaworn, P.3    Pientong, C.4    Ekalaksananan, T.5    Chopjitt, P.6
  • 29
    • 50249090400 scopus 로고    scopus 로고
    • Immunohistochemical assessment of protein phosphorylation state: The dream and the reality
    • Mandell JW,. Immunohistochemical assessment of protein phosphorylation state: the dream and the reality. Histochem Cell Biol. 2008; 130: 465-471.
    • (2008) Histochem Cell Biol , vol.130 , pp. 465-471
    • Mandell, J.W.1
  • 30
    • 0036187615 scopus 로고    scopus 로고
    • The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies
    • Bingle L, Brown NJ, Lewis CE,. The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies. J Pathol. 2002; 196: 254-265.
    • (2002) J Pathol , vol.196 , pp. 254-265
    • Bingle, L.1    Brown, N.J.2    Lewis, C.E.3
  • 32
    • 0033106168 scopus 로고    scopus 로고
    • Transcriptional regulation of the cyclin D1 promoter by STAT5: Its involvement in cytokine-dependent growth of hematopoietic cells
    • Matsumura I, Kitamura T, Wakao H, Tanaka H, Hashimoto K, Albanese C, et al. Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells. EMBO J. 1999; 18: 1367-1377.
    • (1999) EMBO J , vol.18 , pp. 1367-1377
    • Matsumura, I.1    Kitamura, T.2    Wakao, H.3    Tanaka, H.4    Hashimoto, K.5    Albanese, C.6
  • 33
    • 70350500225 scopus 로고    scopus 로고
    • STATs in cancer inflammation and immunity: A leading role for STAT3
    • Yu H, Pardoll D, Jove R,. STATs in cancer inflammation and immunity: a leading role for STAT3. Nat Rev Cancer. 2009; 9: 798-809.
    • (2009) Nat Rev Cancer , vol.9 , pp. 798-809
    • Yu, H.1    Pardoll, D.2    Jove, R.3
  • 35
    • 1042301419 scopus 로고    scopus 로고
    • STAT1-induced apoptosis is mediated by caspases 2, 3, and 7
    • Sironi JJ, Ouchi T,. STAT1-induced apoptosis is mediated by caspases 2, 3, and 7. J Biol Chem. 2004; 279: 4066-4074.
    • (2004) J Biol Chem , vol.279 , pp. 4066-4074
    • Sironi, J.J.1    Ouchi, T.2
  • 36
    • 32644434424 scopus 로고    scopus 로고
    • The role of constitutively active Stat6 in leukemia and lymphoma
    • Bruns HA, Kaplan MH,. The role of constitutively active Stat6 in leukemia and lymphoma. Crit Rev Oncol Hematol. 2006; 57: 245-253.
    • (2006) Crit Rev Oncol Hematol , vol.57 , pp. 245-253
    • Bruns, H.A.1    Kaplan, M.H.2
  • 37
    • 0034658153 scopus 로고    scopus 로고
    • STAT signaling in the pathogenesis and treatment of leukemias
    • Lin TS, Mahajan S, Frank DA,. STAT signaling in the pathogenesis and treatment of leukemias. Oncogene. 2000; 19: 2496-2504.
    • (2000) Oncogene , vol.19 , pp. 2496-2504
    • Lin, T.S.1    Mahajan, S.2    Frank, D.A.3
  • 38
    • 11144357779 scopus 로고    scopus 로고
    • Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells
    • Wang T, Niu G, Kortylewski M, Burdelya L, Shain K, Zhang S, et al. Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells. Nat Med. 2004; 10: 48-54.
    • (2004) Nat Med , vol.10 , pp. 48-54
    • Wang, T.1    Niu, G.2    Kortylewski, M.3    Burdelya, L.4    Shain, K.5    Zhang, S.6
  • 39
    • 0034046605 scopus 로고    scopus 로고
    • STAT family of transcription factors in cytokine-mediated biological responses
    • Takeda K, Akira S,. STAT family of transcription factors in cytokine-mediated biological responses. Cytokine Growth Factor Rev. 2000; 11: 199-207.
    • (2000) Cytokine Growth Factor Rev , vol.11 , pp. 199-207
    • Takeda, K.1    Akira, S.2
  • 40
    • 0029916933 scopus 로고    scopus 로고
    • Activation and association of Stat3 with Src in v-Src-transformed cell lines
    • Cao X, Tay A, Guy GR, Tan YH,. Activation and association of Stat3 with Src in v-Src-transformed cell lines. Mol Cell Biol. 1996; 16: 1595-1603.
    • (1996) Mol Cell Biol , vol.16 , pp. 1595-1603
    • Cao, X.1    Tay, A.2    Guy, G.R.3    Tan, Y.H.4
  • 41
    • 0031953831 scopus 로고    scopus 로고
    • Stat3 activation by Src induces specific gene regulation and is required for cell transformation
    • Turkson J, Bowman T, Garcia R, Caldenhoven E, De Groot RP, Jove R,. Stat3 activation by Src induces specific gene regulation and is required for cell transformation. Mol Cell Biol. 1998; 18: 2545-2552.
    • (1998) Mol Cell Biol , vol.18 , pp. 2545-2552
    • Turkson, J.1    Bowman, T.2    Garcia, R.3    Caldenhoven, E.4    De Groot, R.P.5    Jove, R.6
  • 42
    • 32944479992 scopus 로고    scopus 로고
    • Interleukin 6 upregulates myeloid cell leukemia-1 expression through a STAT3 pathway in cholangiocarcinoma cells
    • Isomoto H, Kobayashi S, Werneburg NW, Bronk SF, Guicciardi ME, Frank DA, et al. Interleukin 6 upregulates myeloid cell leukemia-1 expression through a STAT3 pathway in cholangiocarcinoma cells. Hepatology. 2005; 42: 1329-1338.
    • (2005) Hepatology , vol.42 , pp. 1329-1338
    • Isomoto, H.1    Kobayashi, S.2    Werneburg, N.W.3    Bronk, S.F.4    Guicciardi, M.E.5    Frank, D.A.6
  • 43
    • 33846200831 scopus 로고    scopus 로고
    • Sustained IL-6/STAT-3 signaling in cholangiocarcinoma cells due to SOCS-3 epigenetic silencing
    • Isomoto H, Mott JL, Kobayashi S, Werneburg NW, Bronk SF, Haan S, et al. Sustained IL-6/STAT-3 signaling in cholangiocarcinoma cells due to SOCS-3 epigenetic silencing. Gastroenterology. 2007; 132: 384-396.
    • (2007) Gastroenterology , vol.132 , pp. 384-396
    • Isomoto, H.1    Mott, J.L.2    Kobayashi, S.3    Werneburg, N.W.4    Bronk, S.F.5    Haan, S.6
  • 44
    • 84875244110 scopus 로고    scopus 로고
    • Integrative molecular analysis of intrahepatic cholangiocarcinoma reveals 2 classes that have different outcomes
    • Sia D, Hoshida Y, Villanueva A, Roayaie S, Ferrer J, Tabak B, et al. Integrative molecular analysis of intrahepatic cholangiocarcinoma reveals 2 classes that have different outcomes. Gastroenterology. 2013; 144: 829-840.
    • (2013) Gastroenterology , vol.144 , pp. 829-840
    • Sia, D.1    Hoshida, Y.2    Villanueva, A.3    Roayaie, S.4    Ferrer, J.5    Tabak, B.6
  • 45
    • 84875237481 scopus 로고    scopus 로고
    • Intrahepatic cholangiocarcinoma: Pathogenesis and rationale for molecular therapies
    • Sia D, Tovar V, Moeini A, Llovet JM,. Intrahepatic cholangiocarcinoma: pathogenesis and rationale for molecular therapies. Oncogene. 2013; 32: 4861-4870.
    • (2013) Oncogene , vol.32 , pp. 4861-4870
    • Sia, D.1    Tovar, V.2    Moeini, A.3    Llovet, J.M.4
  • 46
    • 84902299676 scopus 로고    scopus 로고
    • Quercetin and EGCG exhibit chemopreventive effects in cholangiocarcinoma cells via suppression of JAK/STAT signaling pathway
    • Senggunprai L, Kukongviriyapan V, Prawan A, Kukongviriyapan U,. Quercetin and EGCG exhibit chemopreventive effects in cholangiocarcinoma cells via suppression of JAK/STAT signaling pathway. Phytother Res. 2014; 28: 841-848.
    • (2014) Phytother Res , vol.28 , pp. 841-848
    • Senggunprai, L.1    Kukongviriyapan, V.2    Prawan, A.3    Kukongviriyapan, U.4
  • 47
    • 70350041520 scopus 로고    scopus 로고
    • Advanced periductal fibrosis from infection with the carcinogenic human liver fluke Opisthorchis viverrini correlates with elevated levels of interleukin-6
    • Sripa B, Mairiang E, Thinkhamrop B, Laha T, Kaewkes S, Sithithaworn P, et al. Advanced periductal fibrosis from infection with the carcinogenic human liver fluke Opisthorchis viverrini correlates with elevated levels of interleukin-6. Hepatology. 2009; 50: 1273-1281.
    • (2009) Hepatology , vol.50 , pp. 1273-1281
    • Sripa, B.1    Mairiang, E.2    Thinkhamrop, B.3    Laha, T.4    Kaewkes, S.5    Sithithaworn, P.6
  • 48
    • 84863674423 scopus 로고    scopus 로고
    • Elevated plasma IL-6 associates with increased risk of advanced fibrosis and cholangiocarcinoma in individuals infected by Opisthorchis viverrini
    • Sripa B, Thinkhamrop B, Mairiang E, Laha T, Kaewkes S, Sithithaworn P, et al. Elevated plasma IL-6 associates with increased risk of advanced fibrosis and cholangiocarcinoma in individuals infected by Opisthorchis viverrini. PLoS Negl Trop Dis. 2012; 6: e1654.
    • (2012) PLoS Negl Trop Dis , vol.6 , pp. e1654
    • Sripa, B.1    Thinkhamrop, B.2    Mairiang, E.3    Laha, T.4    Kaewkes, S.5    Sithithaworn, P.6


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