Melanoma-initiating cells exploit M2 macrophage TGFβ and arginase pathway for survival and proliferation

Oncotarget

Volumn 5, Issue 23, 2014, Pages 12027-12042

  Tham, Muly ^a   Tan, Kar Wai ^a,g   Keeble, Jo ^a   Wang, Xiaojie ^a   Hubert, Sandra ^a   Barron, Luke ^b   Tan, Nguan Soon ^c   Kato, Masashi ^d   Prevost Blondel, Armelle ^e   Angeli, Veronique ^f   Abastado, Jean Pierre ^a,h  

^a AGENCY FOR SCIENCE   (Singapore)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^d NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e INSTITUT COCHIN   (France)

^f NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^g SINGAPORE GENERAL HOSPITAL   (Singapore)

^h INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

Author keywords

Arginase; Macrophages; TGF ; Tumor initiating cell

Indexed keywords

ARGINASE; CD34 ANTIGEN; POLYAMINE; TEMOZOLOMIDE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CANCER CHEMOTHERAPY; CANCER GROWTH; CELL PROLIFERATION; CELL STIMULATION; CELL SURVIVAL; CONTROLLED STUDY; FEMALE; IMMUNOCOMPETENT CELL; IN VITRO STUDY; IN VIVO STUDY; M2 MACROPHAGE; MACROPHAGE; MALE; MELANOMA; METASTASIS; MOUSE; NONHUMAN; TUMOR ASSOCIATED LEUKOCYTE; TUMOR INITIATING CELL; ANIMAL; CANCER STEM CELL; DISEASE MODEL; IMMUNOLOGY; METABOLISM; MUTANT MOUSE STRAIN; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; ARGINASE; CELL PROLIFERATION; CELL SURVIVAL; DISEASE MODELS, ANIMAL; FEMALE; MACROPHAGES; MALE; MELANOMA; MICE; MICE, MUTANT STRAINS; NEOPLASTIC STEM CELLS; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 84920023709     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.2482     Document Type: Article

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