Inhibition of glycolytic enzyme hexokinase II (HK2) suppresses lung tumor growth

Cancer Cell International

Volumn 16, Issue 1, 2016, Pages

  Wang, Huanan ^a,b   Wang, Lei ^b   Zhang, Yingjie ^b   Wang, Ji ^b   Deng, Yibin ^b   Lin, Degui ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b University of Minnesota Hormel Institute   (United States)

Author keywords

2 DG; Apoptosis; HK2; Kras; NSCLC

Indexed keywords

CRYSTAL VIOLET; DEOXYGLUCOSE; HEXOKINASE; HEXOKINASE 2; K RAS PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE ACTIVITY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; DRUG RESPONSE; ENZYME ASSAY; ENZYME INHIBITION; FLOW CYTOMETRY; GENE MUTATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LUNG CARCINOGENESIS; LUNG TUMOR; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; ONCOGENE K RAS; PROTEIN TARGETING; TUMOR SUPPRESSOR GENE; TUMOR XENOGRAFT; WESTERN BLOTTING;

EID: 84957942935     PISSN: None     EISSN: 14752867     Source Type: Journal    
DOI: 10.1186/s12935-016-0280-y     Document Type: Article

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