A CREB-Sirt1-Hes1 Circuitry Mediates Neural Stem Cell Response to Glucose Availability

Cell Reports

Volumn 14, Issue 5, 2016, Pages 1195-1205

  Fusco, Salvatore ^a,d   Leone, Lucia ^a   Barbati, Saviana Antonella ^a   Samengo, Daniela ^a   Piacentini, Roberto ^a   Maulucci, Giuseppe ^a   Toietta, Gabriele ^b   Spinelli, Matteo ^a   McBurney, Michael ^c   Pani, Giovambattista ^a   Grassi, Claudio ^a,d  

^a CATHOLIC UNIVERSITY   (Italy)

^b REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^c OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^d IRCCS SAN RAFFAELE PISANA   (Italy)

Author keywords

Adult neurogenesis; CREB; Diabetes; Metabolism; Neural stem cells; Nutrients; Sirt 1

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLUCOSE; SIRTUIN 1; TRANSCRIPTION FACTOR HES 1; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; CYCLIC AMP; HES1 PROTEIN, MOUSE; HOMEODOMAIN PROTEIN; LYSINE; PROTEIN BINDING; PROTEIN KINASE;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CREB GENE; GENE; GENE FUNCTION; GENE INTERACTION; GENE REPRESSION; GENETIC TRANSCRIPTION; GLUCOSE BLOOD LEVEL; HES1 GENE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; ANIMAL; CALORIC RESTRICTION; CELL SELF-RENEWAL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HIPPOCAMPUS; METABOLISM;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CALORIC RESTRICTION; CELL SELF RENEWAL; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; GENE EXPRESSION REGULATION; GLUCOSE; HIPPOCAMPUS; HOMEODOMAIN PROTEINS; LYSINE; MICE; NEURAL STEM CELLS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN KINASES; SIRTUIN 1; TRANSCRIPTION FACTOR HES-1;

EID: 84957940019     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.12.092     Document Type: Article

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