Impaired neurogenesis in adult type-2 diabetic rats

Brain Research

Volumn 1258, Issue , 2009, Pages 25-33

  Lang, Bradley T ^a   Yan, Yiping ^a   Dempsey, Robert J ^a   Vemuganti, Raghu ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Animal model; Growth factor; Hyperglycemia; Neural progenitor; Neurospheres; Proliferation; Survival

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; SOMATOMEDIN C; BROXURIDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN FUNCTION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DENTATE GYRUS; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; INSULIN RESISTANCE; LEARNING DISORDER; MEMORY DISORDER; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NEUROLOGIC DISEASE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; RAT; SUBVENTRICULAR ZONE; SURVIVAL; ANALYSIS OF VARIANCE; ANIMAL; CELL CULTURE; DISEASE MODEL; IMMUNOHISTOCHEMISTRY; LATERAL BRAIN VENTRICLE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; STEM CELL; WISTAR KYOTO RAT;

ANIMALIA; RATTUS;

ANALYSIS OF VARIANCE; ANIMALS; BLOOD GLUCOSE; BROMODEOXYURIDINE; CELL SURVIVAL; CELLS, CULTURED; DENTATE GYRUS; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; FIBROBLAST GROWTH FACTOR 2; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; INSULIN-LIKE GROWTH FACTOR I; LATERAL VENTRICLES; NEUROGENESIS; RATS; RATS, INBRED WKY; STEM CELLS;

EID: 64849111978     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.12.026     Document Type: Article

References (42)

1. Aberg,M.A.,Aberg,N.D., Palmer, T.D.,Alborn,A.M.,Carlsson-Skwirut, C., Bang, P., Rosengren, L.E., Olsson, T., Gage, F.H., Eriksson, P.S., 2003. IGF-1 has a direct proliferative effect in adult hippocampal progenitor cells. Mol. Cell. Neurosci. 24, 23-40.
2. Ahmad, T., Ugarph-Morawski, A., Lewitt, M.S., Li, J., Sääf, M., Brismar, K., 2008. Diabetic osteopathy and the IGF system in the Goto-Kakizaki rat. Growth Horm. IGF Res. 18, 404-411.
3. Alvarez-Buylla, A., Seri, B., Doetsch, F., 2002. Identification of neural stem cells in the adult vertebrate brain. Brain Res. Bull. 57, 751-758.
4. Arvidsson, A., Collin, T., Kirik, D., Kokaia, Z., Lindvall, O., 2002. Neuronal replacement from endogenous precursors in the adult brain after stroke. Nat. Med. 8, 963-970.
5. Beauquis, J., Saravia, F., Coulaud, J., Roig, P., Dardenne, M., Homo-Delarche, F., De Nicola, A., 2008. Prominently decreased hippocampal neurogenesis in a spontaneous model of type 1 diabetes, the nonobese diabetic mouse. Exp. Neurol. 210, 359-367.
6. Biessels, G.J., Deary, I.J., Ryan, C.M., 2008. Cognightion and diabetes: a lifespan perspective. Lancet Neurol. 7, 184-190.
7. Cameron, H.A., McKay, R.D., 2001. Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus. J. Comp. Neurol. 435, 406-417.
8. Cimini, A., Cerù, M.P., 2008. Emerging roles of peroxisome proliferator-activated receptors (PPARs) in the regulation of neural stem cells proliferation and differentiation. Stem Cell Rev. 4, 293-303.
9. Das, S., Basu, A., 2008. Inflammation: a new candidate in modulating adult neurogenesis. J. Neurosci. Res. 86, 1199-1208.
10. Dempsey, R.J., Sailor, K.A., Bowen, K.K., Türeyen, K., Vemuganti, R., 2003. Stroke-induced progenitor cell proliferation in adult spontaneously hypertensive rat brain: effect of exogenous IGF-1 and GDNF. J. Neurochem. 87, 586-597.
11. Ekdahl, C.T., Kokaia, Z., Lindvall, O., 2008. Brain inflammation and adult neurogenesis: the dual role of microglia. Neuroscience. doi:10.1016/j.neuroscience.2008.06.052.
12. Gage, F.H., 2000. Mammalian neural stem cells. Science 287, 1433-1438.
13. Goto, Y., Kakisaki, M., Masaki, N., 1975. Spontaneous diabetes produced by repeated selective breeding of normal Wistar rats. Proc. Jpn. Acad. 51, 80-85.
14. Kalluri, H.S., Vemuganti, R., Dempsey, R.J., 2005. Lack of response to epidermal growth factor in adult neural progenitor cells. Neuroreport 16, 835-838.
15. Kalluri, H.S., Vemuganti, R., Dempsey, R.J., 2007. Mechanism of insulin-like growth factor I-mediated proliferation of adult neural progenitor cells: role of Akt. Eur. J. Neurosci. 25, 1041-1048.
16. Kim, S.J., Son, T.G., Park, H.R., Park, M., Kim, M.S., Kim, H.S., Chung, H.Y., Mattson, M.P., Lee, J., 2008. Curcumin stimulates proliferation of embryonic neural progenitor cells and neurogenesis in the adult hippocampus. J. Biol. Chem. 283, 14497-14505.
17. Kodl, C.T., Seaquist, E.R., 2008. Cognitive dysfunction and diabetes mellitus. Endocr. Rev. 29, 494-511.
18. Lindqvist, A., Mohapel, P., Bouter, B., Frielingsdorf, H., Pizzo, D., Brundin, P., Erlanson-Albertsson, C., 2006. High-fat diet impairs hippocampal neurogenesis in male rats. Eur. J. Neurol. 13, 1385-1388.
19. MacLullich, A.M.J., Seckl, J.R., 2008. Diabetes and cognitive decline: are steroids the missing link? Cell Metabolism 7, 286-287.
20. MacLullich, A.M.J., Deary, I.J., Starr, J.M., Walker, B.R., Seckl, J.R., 2004. Glycosylated hemoglobin levels in healthy elderly nondiabetic men and negatively associated with verbal memory. J. Am. Geriatr. Soc. 52, 848-849.
21. Martens, D.J., Seaberg, R.M., van der Kooy, D., 2002. In vivo infusions of exogenous growth factors into the fourth ventricle of the adult mouse brain increase the proliferation of neural progenitors around the fourth ventricle and the central canal of the spinal cord. Eur. J. Neurosci. 16, 1045-1057.
22. Messier, C., 2005. Impact of impaired glucose tolerance and type 2 diabetes on cognitive aging. Neurobiol. Aging 26, S26-S30.
23. Monje, M.L., Toda, H., Palmer, T.D., 2003. Inflammatory blockade restores adult hippocampal neurogenesis. Science 302, 1760-1765.
24. Nakatomi, H., Kuriu, T., Okabe, S., Yamamoto, S., Hatano, O., Kawahara, N., Tamura, A., Kirino, T., Nakafuku, M., 2002. Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors. Cell 110, 429-441.
25. Naylor, M., Bowen, K.K., Sailor, K.A., Dempsey, R.J., Vemuganti, R., 2005. Preconditioning-induced ischemic tolerance stimulates growth factor expression and neurogenesis in adult rat hippocampus. Neurochem. Int. 47, 565-572.
26. Oitzl, M.S., Fluttert, M., Sutanto, W., de Kloet, E.R., 1998. Continuous blockade of brain glucocorticoid receptors facilitates spatial learning and memory in rats. Eur. J. Neurosci. 10, 3759-3766.
27. Palmer, T.D., Ray, J., Gage, F.H., 1995. FGF-2-responsive neuronal progenitors reside in proliferative and quiescent regions of the adult rodent brain. Mol. Cell. Neurosci. 6, 474-486.
28. Palmer, T.D., Markakis, E.A., Willhoite, A.R., Safar, F., Gage, F.H., 1999. Fibroblast growth factor-2 activates a latent neurogenic program in neural stem cells from diverse regions of the adult CNS. J. Neurosci. 19, 8487-8497.
29. Park, S.W., Yan, Y.P., Satriotomo, I., Vemuganti, R., Dempsey, R.J., 2007. Substance P is a promoter of adult neural progenitor cell proliferation under normal and ischemic conditions. J. Neurosurg. 107, 593-599.
30. Paxinos, G., Watson, C., 1998. The Rat Brain in Stereotaxic Coordinates 4th edn. Academic Press, New York.
31. Pluchino, S., Muzio, L., Imitola, J., Deleidi, M., Alfaro-Cervello, C., Salani, G., Porcheri, C., Brambilla, E., Cavasinni, F., Bergamaschi, A., Garcia-Verdugo, J.M., Comi, G., Khoury, S.J., Martino, G., 2008. Persistent inflammation alters the function of the endogenous brain stem cell compartment. Brain 131, 2564-2578.
32. Richards, L.J., Kilpatrick, T.J., Bartlett, P.F., 1992. De novo generation of neuronal cells from the adult mouse brain. Proc. Natl. Acad. Sci. U. S. A. 89, 8591-8595.
33. Stranahan, A.M., Arumugam, T.V., Cutler, R.G., Lee, K., Egan, J.M., Mattson, M.P., 2008. Diabetes impairs hippocampal function through glucocorticoid-mediated effects on new and mature neurons. Nat. Neurosci. 11, 309-317.
34. Taupin, P., 2008. Adult neurogenesis, neuroinflammation and therapeutic potential of adult neural stem cells. Int. J. Med. Sci. 5, 127-132.
35. Toth, C., Martinez, J., Zochodne, D.W., 2007. RAGE, diabetes, and the nervous system. Curr. Mol. Med. 7, 766-776.
36. Türeyen, K., Vemuganti, R., Sailor, K.A., Bowen, K.K., Dempsey, R.J., 2004. Transient focal cerebral ischemia-induced neurogenesis in the dentate gyrus of the adult mouse. J. Neurosurg. 101, 799-805.
37. Tureyen, K., Vemuganti, R., Bowen, K.K., Sailor, K.A., Dempsey, R.J., 2005. EGF and FGF-2 infusion increases post-ischemic neural progenitor cell proliferation in the adult rat brain. Neurosurgery 57, 1254-1263.
38. Tureyen, K., Kapadia, R., Bowen, K.K., Satriotomo, I., Liang, J., Feinstein, D.L., Vemuganti, R., 2007. Peroxisome proliferator-activated receptor-gamma agonists induce neuroprotection following transient focal ischemia in normotensive, normoglycemic as well as hypertensive and type-2 diabetic rodents. J. Neurochem. 101, 41-56.
39. Wiltrout, C., Lang, B., Yan, Y., Dempsey, R.J., Vemuganti, R., 2007. Repairing brain after stroke: a review on post-ischemic neurogenesis. Neurochem. Int. 50, 1028-1041.
40. Yan, Y.P., Sailor, K.A., Vemuganti, R., Dempsey, R.J., 2006. Insulin-like growth factor-1 is an endogenous mediator of focal ischemia-induced neural progenitor proliferation. Eur. J. Neurosci. 24, 45-54.
41. Yan, Y.P., Sailor, K.A., Lang, B.T., Park, S.W., Vemuganti, R., Dempsey, R.J., 2007. Monocyte chemoattractant protein-1 plays a critical role in neuroblast migration after focal cerebral ischemia. J. Cereb. Blood Flow Metab. 27, 1213-1224.
42. Zhang, W.J., Tan, Y.F., Yue, J.T., Vranic, M., Wojtowicz, J.M., 2008. Impairment of hippocampal neurogenesis in streptozotocintreated diabetic rats. Acta Neurol. Scand. 117, 205-210.