Surface decorated nanoparticles as surrogate carriers for improved transport and absorption of epirubicin across the gastrointestinal tract: Pharmacokinetic and pharmacodynamic investigations

International Journal of Pharmaceutics

Volumn 501, Issue 1-2, 2016, Pages 18-31

  Tariq, Mohammad ^a   Alam, Md Aftab ^b   Singh, Anu T ^c   Panda, Amulya K ^d   Talegaonkar, Sushama ^a  

^a HAMDARD UNIVERSITY   (India)

^b GALGOTIAS UNIVERSITY   (India)

^c DABUR RESEARCH FOUNDATION   (India)

^d NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

Author keywords

Anti tumor activity; EAT induced tumor; Mannosylated NPs; Oral bioavailability; Oral delivery; Pegylated NPs

Indexed keywords

EPIRUBICIN; MACROGOL; NANOPARTICLE; POLY LACTIDE CO GLYCOLIC ACID NANOPARTICLE; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIBIOTIC; DRUG CARRIER; HEXOSAMINE; LACTIC ACID; MACROGOL DERIVATIVE; MANNOSAMINE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CACO 2 CELL LINE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG EFFECT; DRUG SYNTHESIS; DRUG TRANSPORT; DRUG UPTAKE; ENDOCYTOSIS; FLOW CYTOMETRY; GASTROINTESTINAL TRACT; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MCF 7 CELL LINE; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; CACO-2 CELL LINE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; DRUG RELEASE; ILEUM; INTESTINE ABSORPTION; MCF-7 CELL LINE; METABOLISM; SURFACE PROPERTY; TRANSPORT AT THE CELLULAR LEVEL; WISTAR RAT;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CELL SURVIVAL; DRUG CARRIERS; DRUG LIBERATION; EPIRUBICIN; GASTROINTESTINAL TRACT; HEXOSAMINES; HUMANS; ILEUM; INTESTINAL ABSORPTION; LACTIC ACID; MCF-7 CELLS; NANOPARTICLES; POLYETHYLENE GLYCOLS; POLYGLYCOLIC ACID; RATS, WISTAR; SURFACE PROPERTIES;

EID: 84957825062     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2016.01.054     Document Type: Article

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