Effects of protein binding on the biodistribution of PEGylated PLGA nanoparticles post oral administration

International Journal of Pharmaceutics

Volumn 424, Issue 1-2, 2012, Pages 115-120

  Semete, Boitumelo ^a   Booysen, Laetitia ^a,b   Kalombo, Lonji ^a   Ramalapa, Bathabile ^a   Hayeshi, Rose ^a   Swai, Hulda S ^a  

^a DSI CSIR Nanotechnology Innovation Centre   (South Africa)

^b NORTH WEST UNIVERSITY   (South Africa)

Author keywords

Biodistribution; Nanoparticles; PEGylation; Protein binding

Indexed keywords

MACROGOL; NANOPARTICLE; POLOXAMER;

ANIMAL EXPERIMENT; ARTICLE; COATED PARTICLE; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG PROTEIN BINDING; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ADMINISTRATION, ORAL; ANIMALS; BLOOD PROTEINS; DRUG CARRIERS; FEMALE; HUMANS; LACTIC ACID; MICE; MICE, INBRED BALB C; NANOPARTICLES; POLOXAMER; POLYETHYLENE GLYCOLS; POLYGLYCOLIC ACID; PROTEIN BINDING; TISSUE DISTRIBUTION;

EID: 84856956871     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.12.043     Document Type: Article

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