Whole-Genome Sequencing Reveals Diverse Models of Structural Variations in Esophageal Squamous Cell Carcinoma

American Journal of Human Genetics

Volumn 98, Issue 2, 2016, Pages 256-274

  Cheng, Caixia ^a   Zhou, Yong ^b   Li, Hongyi ^a   Xiong, Teng ^b   Li, Shuaicheng ^c   Bi, Yanghui ^a   Kong, Pengzhou ^a   Wang, Fang ^a   Cui, Heyang ^a,b   Li, Yaoping ^a,d   Fang, Xiaodong ^b   Yan, Ting ^a   Li, Yike ^a   Wang, Juan ^a   Yang, Bin ^a,d   Zhang, Ling ^a   Jia, Zhiwu ^a   Song, Bin ^a   Hu, Xiaoling ^a   Yang, Jie ^a   Qiu, Haile ^a   Zhang, Gehong ^a   Liu, Jing ^a   Xu, Enwei ^d   Shi, Ruyi ^a   Zhang, Yanyan ^a   Liu, Haiyan ^a   He, Chanting ^a   Zhao, Zhenxiang ^a   Qian, Yu ^a   Rong, Ruizhou ^a   Han, Zhiwei ^a   Zhang, Yanlin ^c   Luo, Wen ^b   Wang, Jiaqian ^b   Peng, Shaoliang ^e   Yang, Xukui ^b   Li, Xiangchun ^b   Li, Lin ^b   Fang, Hu ^b   Liu, Xingmin ^b   Ma, Li ^d   Chen, Yunqing ^d   Guo, Shiping ^d   Chen, Xing ^f   Xi, Yanfeng ^d   Li, Guodong ^d   Liang, Jianfang ^a   Yang, Xiaofeng ^a   Guo, Jiansheng ^a   Jia, Junmei ^a   Li, Qingshan ^a   Cheng, Xiaolong ^a   Zhan, Qimin ^g   Cui, Yongping ^a   more..

^a SHANXI MEDICAL UNIVERSITY   (China)

^b BGI SHENZHEN   (China)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

^d SHANXI CANCER HOSPITAL   (China)

^e NATIONAL UNIVERSITY OF DEFENSE TECHNOLOGY   (China)

^f SHAANXI PROVINCIAL PEOPLE S HOSPITAL   (China)

^g CANCER HOSPITAL   (China)

Author keywords

breakage fusion bridge; chromothripsis; ESCC; structural variation; whole genome duplication

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR RECEPTOR 1; LETM2 PROTEIN; METALLOPROTEINASE; MYC PROTEIN; NOTCH1 RECEPTOR; ONCOPROTEIN; UNCLASSIFIED DRUG; CCND1 PROTEIN, HUMAN; CYCLIN D1; EGFR PROTEIN, HUMAN; ERBB2 PROTEIN, HUMAN; FGFR1 PROTEIN, HUMAN; NOTCH1 PROTEIN, HUMAN;

ALLELIC IMBALANCE; ARTICLE; CANCER GENETICS; CARCINOGENESIS; CHROMOSOME NUMBER; CLINICAL ARTICLE; CONTROLLED STUDY; COPY NUMBER VARIATION; DNA END JOINING REPAIR; DOUBLE MINUTE CHROMOSOME; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; GENE AMPLIFICATION; GENE DELETION; GENE DISRUPTION; GENE DUPLICATION; GENE FREQUENCY; GENE FUSION; GENE REARRANGEMENT; GENE SEQUENCE; GENE STRUCTURE; GENE TARGETING; GENE TRANSLOCATION; GENETIC VARIABILITY; HUMAN; IMMUNOHISTOCHEMISTRY; MOLECULAR PATHOLOGY; ONCOGENE; PRIORITY JOURNAL; RNA SEQUENCE; SOMATIC MUTATION; CELL LINE; ESOPHAGUS TUMOR; FLUORESCENCE IN SITU HYBRIDIZATION; GENETIC ASSOCIATION STUDY; GENETIC VARIATION; GENETICS; GENOMICS; HUMAN GENOME; PROCEDURES; REPRODUCIBILITY; SEQUENCE ANALYSIS; SQUAMOUS CELL CARCINOMA; TUMOR SUPPRESSOR GENE;

CARCINOMA, SQUAMOUS CELL; CELL LINE; CYCLIN D1; DNA COPY NUMBER VARIATIONS; ESOPHAGEAL NEOPLASMS; GENE DELETION; GENE REARRANGEMENT; GENES, P16; GENETIC ASSOCIATION STUDIES; GENETIC VARIATION; GENOME, HUMAN; GENOMICS; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; RECEPTOR, NOTCH1; REPRODUCIBILITY OF RESULTS; SEQUENCE ANALYSIS, RNA; TRANSLOCATION, GENETIC;

EID: 84957799431     PISSN: 00029297     EISSN: 15376605     Source Type: Journal    
DOI: 10.1016/j.ajhg.2015.12.013     Document Type: Article

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