EGFR inhibitors prevent induction of cancer stem-like cells in esophageal squamous cell carcinoma by suppressing epithelial-mesenchymal transition

Cancer Biology and Therapy

Volumn 16, Issue 6, 2015, Pages 933-940

  Sato, Fumiyuki ^a   Kubota, Yoshimasa ^a   Natsuizaka, Mitsuteru ^a   Maehara, Osamu ^b   Hatanaka, Yutaka ^c   Marukawa, Katsuji ^c   Terashita, Katsumi ^c   Suda, Goki ^a   Ohnishi, Shunsuke ^a   Shimizu, Yuichi ^a   Komatsu, Yoshito ^a   Ohashi, Shinya ^d   Kagawa, Shingo ^e   Kinugasa, Hideaki ^f   Whelan, Kelly A ^g,h   Nakagawa, Hiroshi ^g,h   Sakamoto, Naoya ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c HOKKAIDO UNIVERSITY HOSPITAL   (Japan)

^d KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^e CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^f OKAYAMA UNIVERSITY   (Japan)

^g UNIVERSITY OF PENNSYLVANIA   (United States)

^h UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Cancer stem cell; EGFR inhibitor; Epithelial mesenchymal transition; Esophageal squamous cell carcinoma; Organotypic

Indexed keywords

CETUXIMAB; ERLOTINIB; HERMES ANTIGEN; NOTCH1 RECEPTOR; NOTCH3 RECEPTOR; TRANSCRIPTION FACTOR ZEB1; TRANSFORMING GROWTH FACTOR BETA1; EPIDERMAL GROWTH FACTOR RECEPTOR; HOMEODOMAIN PROTEIN; TRANSCRIPTION FACTOR; ZEB1 PROTEIN, HUMAN;

ARTICLE; CANCER CELL CULTURE; CANCER STEM CELL; CARCINOGENESIS; CELL DIFFERENTIATION; CELL INVASION; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; PROTEIN EXPRESSION; TISSUE ENGINEERING; TUMOR INVASION; ANTAGONISTS AND INHIBITORS; CELL PROLIFERATION; DRUG EFFECTS; DRUG RESISTANCE; ESOPHAGUS TUMOR; METABOLISM; MULTICELLULAR SPHEROID; PATHOLOGY; SQUAMOUS CELL CARCINOMA; TUMOR CELL CULTURE; TUMOR CELL LINE; TUMOR VOLUME;

CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG RESISTANCE, NEOPLASM; EPITHELIAL-MESENCHYMAL TRANSITION; ERLOTINIB HYDROCHLORIDE; ESOPHAGEAL NEOPLASMS; HOMEODOMAIN PROTEINS; HUMANS; NEOPLASTIC STEM CELLS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SPHEROIDS, CELLULAR; TRANSCRIPTION FACTORS; TUMOR BURDEN; TUMOR CELLS, CULTURED; ZINC FINGER E-BOX-BINDING HOMEOBOX 1;

EID: 84943758352     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.1080/15384047.2015.1040959     Document Type: Article

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