Review of endocrine disorders associated with environmental toxicants and possible involved mechanisms

Life Sciences

Volumn 145, Issue , 2016, Pages 265-273

  Maqbool, Faheem ^a,b   Mostafalou, Sara ^c   Bahadar, Haji ^a   Abdollahi, Mohammad ^a,d  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b GOVERNMENT COLLEGE UNIVERSITY   (Pakistan)

^c ARDABIL UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Aneuploidy; Bisphenol A; Endocrine disruptors; Environment; Estrogens; Neoplasm; Steroids; Systematic review

Indexed keywords

CELL NUCLEUS RECEPTOR; ENDOCRINE DISRUPTOR; FUEL; PESTICIDE; PLASTIC; PLASTICIZER; STEROID HORMONE; XENOBIOTIC AGENT; CARCINOGEN; HORMONE; POLLUTANT;

ALZHEIMER DISEASE; ARTICLE; BREAST CANCER; CARCINOGENICITY; DIABETES MELLITUS; DNA METHYLATION; ENDOCRINE DISEASE; GENE MUTATION; HORMONE METABOLISM; HUMAN; INDUSTRIAL WASTE; NERVE INJURY; OBESITY; OVARY CANCER; OVARY DISEASE; OXIDATIVE STRESS; SCHIZOPHRENIA; TESTIS CARCINOMA; THYROID DISEASE; ADVERSE EFFECTS; ANIMAL; CARDIOVASCULAR SYSTEM; DRUG EFFECTS; ENVIRONMENTAL EXPOSURE; METABOLISM; NERVOUS SYSTEM; POLLUTANT; REPRODUCTION; TOXICITY;

ANIMALS; CARCINOGENS, ENVIRONMENTAL; CARDIOVASCULAR SYSTEM; ENDOCRINE DISRUPTORS; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; HORMONES; HUMANS; NERVOUS SYSTEM; OBESITY; REPRODUCTION;

EID: 84957562232     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2015.10.022     Document Type: Article

References (127)

1. D.V. Henley, and K.S. Korach Endocrine-disrupting chemicals use distinct mechanisms of action to modulate endocrine system function Endocrinology 147 2006 25 32
2. World Health Organization State of the Science of Endocrine Disrupting Chemicals: An Assessment of the State of the Science of Endocrine Disputors Prepared by a Group of Experts for the United Nations Environment Programme (UNEP) and WHO 2013 296 (http://www.who.int/ceh/publications/endocrine/en/ accessed 18 September, 2015)
3. E. Diamanti-Kandarakis, J.P. Bourguignon, L.C. Giudice, R. Hauser, and et al. Endocrine-disrupting chemicals: an endocrine society scientific statement Endocr. Rev. 30 2009 293 342
4. A.C. Johnson, and J.P. Sumpter Removal of endocrine-disrupting chemicals in activated sludge treatment works Environ. Sci. Technol. 35 2001 4697 4703
5. F. Maqbool, H. Bahadar, and M. Abdollahi Exposure to mercury from dental amalgams: a threat to society Arh. Hig. Rada. Toksikol. 65 2014 339 340
6. R.A. Rudel, D.E. Camann, J.D. Spengler, L.R. Korn, and et al. Phthalates, alkylphenols, pesticides, polybrominated diphenyl ethers, and other endocrine-disrupting compounds in indoor air and dust Environ. Sci. Technol. 37 2003 4543 4553
7. B. Aurela, H. Kulmala, and L. Soderhjelm Phthalates in paper and board packaging and their migration into Tenax and sugar Food Addit. Contam. 16 1999 571 577
8. S. Saeidnia, and M. Abdollahi Are medicinal plants polluted with phthalates? Daru 21 2013 21:43
9. S. Mostafalou, and M. Abdollahi Pesticides and human chronic diseases: evidence, mechanisms, and perspectives Toxicol. Appl. Pharmacol. 268 2013 157 177
10. S. Mostafalou, and M. Abdollahi Concerns of environmental persistence of pesticides and human chronic diseases Clin. Exp. Pharmacol. 2 2012 3
11. G.G. Kuiper, J.G. Lemmen, B. Carlsson, J.C. Corton, and et al. Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor β Endocrinology 139 1998 4252 4263
12. S.M. Dickerson, and A.C. Gore Estrogenic environmental endocrine-disrupting chemical effects on reproductive neuroendocrine function and dysfunction across the life cycle Rev. Endocr. Metab. Disord. 8 2007 143 159
13. W. Miller, and R. Sharpe Environmental oestrogens and human reproductive cancers Endocr. Relat. Cancer. 5 1998 69 96
14. J. Toppari, J.C. Larsen, P. Christiansen, A. Giwercman, and et al. Male reproductive health and environmental xenoestrogens Environ. Health Perspect. 104 1996 741
15. M.V. Maffin, B.S. Rubin, C. Sonnenschein, and A.M. Soto Endocrine disruptors and reproductive health: the case of bisphenol-A Mol. Cell. Endocrinol. 254 2006 179 186
16. N. Skakkebaek, E. Rajpert-De Meyts, and K. Main Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects: opinion Hum. Reprod. 16 2001 972 978
17. E. Carlsen, A. Giwercman, N. Keiding, and N.E. Skakkebaek Evidence for decreasing quality of semen during past 50 years BMJ 305 1992 609 613
18. R.M. Sharpe, and N.E. Skakkebaek Are oestrogens involved in falling sperm counts and disorders of the male reproductive tract? Lancet 342 1993 1392 1395
19. A.C. Gore Organochlorine pesticides directly regulate gonadotropin-releasing hormone gene expression and biosynthesis in the GT1-7 hypothalamic cell line Mol. Cell. Endocrinol. 192 2002 157 170
20. J.A. Staessen, T. Nawrot, E.D. Hond, L. Thijs, and et al. Renal function, cytogenetic measurements, and sexual development in adolescents in relation to environmental pollutants: a feasibility study of biomarkers Lancet 357 2001 1660 1669
21. I.S. Weidner, H. Møller, T.K. Jensen, and N.E. Skakkebaek Cryptorchidism and hypospadias in sons of gardeners and farmers Environ. Health Perspect. 106 1998 793
22. J. Biles, T. McNeal, T. Begley, and H. Hollifiel Determination of bisphenol-A in reusable polycarbonate food-contact plastics and migration to food-simulating liquids J. Agric. Food Chem. 45 1997 3541 3544
23. P.A. Hunt, K.E. Koehler, M. Susiarjo, C.A. Hodges, and et al. Bisphenol a exposure causes meiotic aneuploidy in the female mouse Curr. Biol. 13 2003 546 553
24. Y. Ikezuki, O. Tsutsumi, Y. Takai, Y. Kamei, and et al. Determination of bisphenol A concentrations in human biological fluids reveals significant early prenatal exposure Hum. Reprod. 17 2002 2839 2841
25. T. Hassold, and P. Hunt To err (meiotically) is human: the genesis of human aneuploidy Nat. Rev. Genet. 2 2001 280 291
26. M. Sugiura-Ogasawara, Y. Ozaki, S. Sonta, T. Makino, and et al. Exposure to bisphenol A is associated with recurrent miscarriage Hum. Reprod. 20 2005 2325 2329
27. T. Colborn, F.S. vom Saal, and A.M. Soto Developmental effects of endocrine-disrupting chemicals in wildlife and humans Environ. Health Perspect. 101 1993 101:378
28. S.M. Choi, S.D. Yoo, and B.M. Lee Toxicological characteristics of endocrine-disrupting chemicals: developmental toxicity carcinogenicity and mutagenicity J. Toxicol. Environ. Health B 7 2004 1 23
29. A.M. Sot, and C. Sonnenschein Environmental causes of cancer: endocrine disruptors as carcinogens Nat. Rev. Endocrinol. 6 2010 363 370
30. L.S. Birnbaum, and S.E. Fenton Cancer and developmental exposure to endocrine disruptors Environ. Health Perspect. 111 2003 389
31. F.E. Alexander, S.L. Patheal, A. Biondi, S. Brandalise, and et al. Transplacental chemical exposure and risk of infant leukemia with MLL gene fusion Cancer Res. 61 2001 2542 2546
32. G. Löfroth Environmental tobacco smoke: overview of chemical composition and genotoxic components Mutat. Res. Genet. Toxicol. 222 1989 73 80
33. P.C. Das, W.K. McElroy, and R.L. Cooper Alteration of catecholamines in pheochromocytoma (PC12) cells in vitro by the metabolites of chlorotriazine herbicide Toxicol. Sci. 59 2001 127 137
34. R.L. Cooper, T.E. Stoker, L. Tyrey, J.M. Goldman, and et al. Atrazine disrupts the hypothalamic control of pituitary-ovarian function Toxicol. Sci. 53 2000 297 307
35. A. Jemal, R. Siegel, E. Ward, T. Murray, J. Xu, and et al. Cancer statistics CA Cancer J. Clin. 56 2006 106 130
36. G.S. Prins, and K.S. Korach The role of estrogens and estrogen receptors in normal prostate growth and disease Steroids 73 2008 233 244
37. D.L. Davis, H.L. Bradlow, M. Wolff, T. Woodruff, and et al. Medical hypothesis: xenoestrogens as preventable causes of breast cancer Environ. Health Perspect. 102 1993 372 377
38. E. Williams, L. Jones, M. Vessey, and K. McPherson Short term increase in risk of breast cancer associated with full term pregnancy BMJ 1990 300 578
39. M.L. Jugan, Y. Levi, and J.P. Blondeau Endocrine disruptors and thyroid hormone physiology Biochem. Pharmacol. 79 2010 939 947
40. K. Moriyama, T. Tagami, T. Akamizu, U.T. Sui, and et al. Thyroid hormone action is disrupted by bisphenol A as an antagonist J. Clin. Endocrinol. Metab. 87 2002 5185 5190
41. M. Boas, U. Feldt-Rasmussen, N.E. Skakkebæk, and K.M. Main Environmental chemicals and thyroid function Eur. J. Endocrinol. 154 2006 599 611
42. A.O. Cheek, K. Kow, J. Chen, and J.A. McLachlan Potential mechanisms of thyroid disruption in humans: interaction of organochlorine compounds with thyroid receptor, transthyretin, and thyroid-binding globulin Environ. Health Perspect. 107 1999 273
43. S.L. Schantz, B.W. Seo, J. Moshtaghian, and S. Amin Developmental exposure to polychlorinated biphenyls or dioxin: do changes in thyroid function mediate effects on spatial learning? Am. Zool. 37 1997 399 408
44. E.S. Goldey, L.S. Kehn, C. Lau, G.L. Rehnberg, and K.M. Crofton Developmental exposure to polychlorinated biphenyls (Aroclor 1254) reduces circulating thyroid hormone concentrations and causes hearing deficits in rats Toxicol. Appl. Pharmacol. 135 1995 77 88
45. J.J. Byrne, J.P. Carbone, and E.A. Hanson Hypothyroidism and abnormalities in the kinetics of thyroid hormone metabolism in rats treated chronically with polychlorinated biphenyl and polybrominated biphenyl Endocrinology 121 1987 520 527
46. C. Koopman-Esseboom, M. Huisman, B.C. Touwen, E.R. Boersma, and et al. Newborn infants diagnosed as neurologically abnormal with relation to PCB and dioxin exposure and their thyroid-hormone status Dev. Med. Child Neurol. 39 1997 785
47. P.M. Hurley Mode of carcinogenic action of pesticides inducing thyroid follicular cell tumors in rodents Environ. Health Perspect. 106 1998 437
48. J. Ashby, L. Kier, A.G. Wilson, T. Green, and et al. Evaluation of the potential carcinogenicity and genetic toxicity to humans of the herbicide acetochlor Hum. Exp. Toxicol. 15 1996 702 735
49. J. McKinney, R. Fannin, S. Jordan, K. Chae, U. Rickenbacher, and et al. Polychlorinated biphenyls and related compound interactions with specific binding sites for thyroxine in rat liver nuclear extracts J. Med. Chem. 30 1987 79 86
50. P.O. Darnerud, D. Morse, E. Klasson-Wehler, and A. Brouwer Binding of a 3,3′, 4,4′-tetrachlorobiphenyl (CB-77) metabolite to fetal transthyretin and effects on fetal thyroid hormone levels in mice Toxicology 106 1996 105 114
51. U. Rickenbacher, J.D. McKinney, S.J. Oatley, and C.C. Blake Structurally specific binding of halogenated biphenyls to thyroxine transport protein J. Med. Chem. 29 1986 641 648
52. R. Green, R. Hauser, A.M. Calafat, J. Weuve, T., and et al. Use of di(2-ethylhexyl) phthalate-containing medical products and urinary levels of mono(2-ethylhexyl) phthalate in neonatal intensive care unit infants Environ. Health Perspect. 113 2005 1222 1225
53. F.E. Mitchell, S.C. Price, R.H. Hinton, P. Grasso, and et al. Time and dose-response study of the effects on rats of the plasticizer di (2-ethylhexyl) phthalate Toxicol. Appl. Pharmacol. 81 1985 371 392
54. R.H. Hinton, F.E. Mitchell, A. Mann, D. Chescoe, and et al. Effects of phthalic acid esters on the liver and thyroid Environ. Health Perspect. 70 1986 195 210
55. S.C. Price, D. Chescoe, P. Grasso, M. Wright, and R.H. Hinton Alterations in the thyroids of rats treated for long periods with di-(2-ethylhexyl) phthalate or with hypolipidaemic agents Toxicol. Lett. 40 1988 37 46
56. M. Soni, I. Carabin, and G. Burdock Safety assessment of esters of p-hydroxybenzoic acid (parabens) Food Cosmet. Toxicol. 43 2005 985 1015
57. B. Rousset Antithyroid effect of a food or drug preservative: 4-hydroxybenzoic acid methyl ester Experientia 37 1981 177 178
58. E.J. Scollon, J.A. Carr, and G.P. Cobb The effect of flight, fasting and p,p′-DDT on thyroid hormones and corticosterone in Gambel's white-crowned sparrow, Zonotrichia leucophrys gambelli Comp. Biochem. Physiol. C Toxicol. Pharmacol. 137 2004 179 189
59. K. Rozman, J.R. Gorski, P. Rozman, and A. Parkinson Reduced serum thyroid hormone levels in hexachlorobenzene-induced porphyria Toxicol. Lett. 30 1986 71 78
60. R.R. Newbold, E. Padilla-Banks, W.N. Jefferson, and J.J. Heindel Effects of endocrine disruptors on obesity Int. J. Androl. 31 2008 201 208
61. P.F. Baillie-Hamilton Chemical toxins: a hypothesis to explain the global obesity epidemic J. Altern. Complement. Med. 8 2002 185 192
62. F. Maqbool, M. Safavi, H. Bahadar, M. Rahimifard, K. Niaz, and M. Abdollahi Discovery approaches for novel dyslipidemia drugs Curr. Drug. Discov. Technol. 12 2015 90 116
63. R.R. Newbold, E. Padilla-Banks, R.J. Snyder, and W.N. Jefferson Perinatal exposure to environmental estrogens and the development of obesity Mol. Nutr. Food Res. 51 2007 912 917
64. C. Le May, K. Chu, M. Hu, C.S. Ortega, and et al. Estrogens protect pancreatic beta-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice Proc. Natl. Acad. Sci. 103 2006 9232 9237
65. A. Nadal, P. Alonso-Magdalena, S. Soriano, and I. Quesada The pancreatic β-cell as a target of estrogens and xenoestrogens: implications for blood glucose homeostasis and diabetes Mol. Cell. Endocrinol. 304 2009 63 68
66. A.B. Ropero, P. Alonso-Magdalena, I. Quesada, and A. Nadal The role of estrogen receptors in the control of energy and glucose homeostasis Steroids 73 2008 874 879
67. D.H. Lee, I.K. Lee, K. Song, M. Steffes, and et al. A strong dose-response relation between serum concentrations of persistent organic pollutants and diabetes results from the national health and examination survey 1999-2002 Diabetes Care 29 2006 1638 1644
68. R.B. Remillard, and N.J. Bunce Linking dioxins to diabetes: epidemiology and biologic plausibility Environ. Health Perspect. 110 2002 853 858
69. P. Alonso-Magdalena, E. Vieira, S. Soriano, L. Menes, and et al. Bisphenol A exposure during pregnancy disrupts glucose homeostasis in mothers and adult male offspring Environ. Health Perspect. 118 2010 1243
70. 2 + signals in pancreatic alpha-cells through a nonclassical membrane estrogen receptor within intact islets of Langerhans Environ. Health Perspect. 113 2005 969 977
71. P. Alonso-Magdalena, I. Quesada, and A. Nadal Endocrine disruptors in the etiology of type 2 diabetes mellitus Nat. Rev. Endocrinol. 7 2011 346 353
72. P. Poirier, and J.P. Despres Waist circumference, visceral obesity, and cardiovascular risk J. Cardpulm. Rehabil. 23 2003 161 169
73. S. Collins Overview of clinical perspectives and mechanisms of obesity Birth. Defects Res. A. Clin. Mol. Teratol. 73 2005 470 471
74. A.H. Mokdad, E.S. Ford, B.A. Bowman, W.H. Dietz, F., and et al. Prevalence of obesity, diabetes, and obesity-related health risk factors JAMA 289 2003 76 79
75. P.M. Lind, and L. Lind Circulating levels of bisphenol A and phthalates are related to carotid atherosclerosis in the elderly Atherosclerosis 218 2011 207 213
76. A. Sergeev, and D. Carpenter Residential proximity to environmental sources of persistent organic pollutants and first-time hospitalizations for myocardial infarction with comorbid diabetes mellitus: a 12-year population-based study Int. J. Occup. Environ. Health 23 2010 5 13
77. H. Uemura, K. Arisawa, M. Hiyoshi, A. Kitayama, and et al. Prevalence of metabolic syndrome associated with body burden levels of dioxin and related compounds among Japan's general population Environ. Health Perspect. 117 2009 568 573
78. P.A. Bertazzi, I. Bernucci, G. Brambilla, D. Consonni, and A.C. Pesatori The Seveso studies on early and long-term effects of dioxin exposure: a review Environ. Health Perspect. 2 1998 625 633
79. J. Flesch-Janys, P. Berger, A. Gum, S. Manz, H. Nagel, H. Waltsgott, and et al. Exposure to polychlorinated dioxins and furans (PCDD/F) and mortality in a cohort of workers from a herbicide-producing plant in Hamburg, Federal Republic of Germany Am. J. Epidemiol. 142 1995 1165 1175
80. J. Vena, P. Boffetta, H. Becher, T. Benn, and et al. Exposure to dioxin and nonneoplastic mortality in the expanded IARC international cohort study of phenoxy herbicide and chlorophenol production workers and sprayers Environ. Health Perspect. 106 1998 645
81. T.T. Schug, A. Janesick, B. Blumberg, and J.J. Heindel Endocrine disrupting chemicals and disease susceptibility J. Steroid Biochem. Mol. Biol. 127 2011 204 215
82. C. Frye, E. Bo, G. Calamandrei, L. Calzà, F. Dessì-Fulgheri, and et al. Endocrine disrupters: a review of some sources effects and mechanisms of actions on behaviour and neuroendocrine systems J. Neuroendocrinol. 24 2012 144 159
83. J.S. Brown Effects of bisphenol-A and other endocrine disruptors compared with abnormalities of schizophrenia: an endocrine-disruption theory of schizophrenia Schizophr. Bull. 35 2009 256 278
84. Y. Kaneda, and T. Ohmori Relation between estradiol and negative symptoms in men with schizophrenia J. Neuropsychiatr. Clin. Neurosci. 17 2005 239 242
85. M. Segal, A. Avital, S. Berstein, A. Derevenski, and et al. Prolactin and estradiol serum levels in unmedicated male paranoid schizophrenia patients Prog. Neuro-Psychopharmacol. Biol. Psychiatry 31 2007 378 382
86. T.J. Huber, J. Rollnik, J. Wilhelms, A. von zur Muhlen, et al., Estradiol levels in psychotic disorders, Psychoneuroendocrinology 26 (2001) 27-35.
87. T.J. Huber, M. Borsutzky, U. Schneider, and H.M. Emrich Psychotic disorders and gonadal function: evidence supporting the oestrogen hypothesis Acta Psychiatr. Scand. 109 2004 269 274
88. T.I. Prior, P.S. Chue, and P. Tibbo Investigation of Turner syndrome in schizophrenia Am. J. Med. Genet. 96 2000 373 378
89. L.E. DeLisi, A.M. Maurizio, C. Svetina, B. Ardekani, and et al. Klinefelter's syndrome (XXY) as a genetic model for psychotic disorders Am. J. Med. Genet. B Neuropsychiatr. Genet. 5 2005 15 23
90. D. Cotter, and C.M. Pariante Stress and the progression of the developmental hypothesis of schizophrenia Br. J. Psychiatry 181 2002 363 365
91. N. Ingram, S. Marti, J.h. Wang, S. van der Laan, R. Loiacono, and M. van den Buuse Interaction of corticosterone and nicotine in regulation of prepulse inhibition in mice Neuropharmacology 48 2005 80 92
92. M. van den Buuse, M. Morris, C. Chavez, S. Martin, and et al. Effect of adrenalectomy and corticosterone replacement on prepulse inhibition and locomotor activity in mice Br. J. Pharmacol. 142 2004 543 550
93. J. Kimura-Kuroda, I. Nagata, and Y. Kuroda Disrupting effects of hydroxy-polychlorinated biphenyl (PCB) congeners on neuronal development of cerebellar Purkinje cells: a possible causal factor for developmental brain disorders? Chemosphere 67 2007 16
94. Y. Masuo, M. Morita, S. Oka, and M. Ishido Motor hyperactivity caused by a deficit in dopaminergic neurons and the effects of endocrine disruptors: a study inspired by the physiological roles of PACAP in the brain Regul. Pept. 123 2004 225 234
95. Y. Watanabe, S. Hashimoto, A. Kakita, H. Takahashi, and et al. Neonatal impact of leukemia inhibitory factor on neurobehavioral development in rats Neurosci. Res. 48 2004 345 353
96. E.D. Cadman, D.G. Witte, and C.M. Lee Regulation of the release of interleukin-6 from human astrocytoma cells J. Neurochem. 63 1994 980 987
97. X.Y. Zhang, D.F. Zhou, P.Y. Zhang, G.Y. Wu, and et al. Elevated interleukin-2, interleukin-6 and interleukin-8 serum levels in neuroleptic-free schizophrenia: association with psychopathology Schizophr. Res. 57 2002 247 258
98. S.F. Ali, C.P. LeBel, and S.C. Bondy Reactive oxygen species formation as a biomarker of methylmercury and trimethyltin neurotoxicity Neurotoxicology 13 1991 637 648
99. J. Salama, T.R. Chakraborty, L. Ng, and A.C. Gore Effects of polychlorinated biphenyls on estrogen receptor-beta expression in the anteroventral periventricular nucleus Environ. Health Perspect. 111 2003 1278
100. M. Fernandez, M. Paradisi, G. D'Intino, G. Del Vecchio, and et al. A single prenatal exposure to the endocrine disruptor 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin alters developmental myelination and remyelination potential in the rat brain J. Neurochem. 115 2010 897 909
101. J.A. Head, M.E. Hahn, and S.W. Kennedy Key amino acids in the aryl hydrocarbon receptor predict dioxin sensitivity in avian species Environ. Sci. Technol. 42 2008 7535 7541
102. D.R. Bell, S. Clode, M.Q. Fan, A. Fernandes, and et al. Interpretation of studies on the developmental reproductive toxicology of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in male offspring Food Chem. Toxicol. 48 2010 1439 1447
103. A. Nadal, M. Díaz, and M.A. Valverde The estrogen trinity: membrane, cytosolic, and nuclear effects Physiology 16 2001 251 255
104. S. Saeidnia, and M. Abdollahi Toxicological and pharmacological concerns on oxidative stress and related diseases Toxicol. Appl. Pharmacol. 15 2013 442 455
105. E. Swedenborg, J. Rüegg, S. Mäkelä, and I. Pongratz Endocrine disruptive chemicals: mechanisms of action and involvement in metabolic disorders J. Mol. Endocrinol. 43 2009 1 10
106. J.T. Sanderson The steroid hormone biosynthesis pathway as a target for endocrine-disrupting chemicals Toxicol. Sci. 94 2006 3 21
107. K. Fent, and J.J. Stegeman Effects of tributyltin chloride in vitro on the hepatic microsomal monooxygenase system in the fish Stenotomus chrysops Aquat. Toxicol. 20 1991 159 168
108. K. Fent Ecotoxicological problems associated with contaminated sites Toxicol. Lett. 140 2003 353 365
109. M.M. Hart, R.L. Reagan, and R.H. Adamson The effect of isomers of DDD on the ACTH-induced steroid output, histology and ultrastructure of the dog adrenal cortex Toxicol. Appl. Pharmacol. 24 1973 101 113
110. H. Bahadar, S. Mostafalou, and M. Abdollahi Current understandings and perspectives on non-cancer health effects of benzene: a global concern Toxicol. Appl. Pharmacol. 15 2014 83 94
111. B.O. Lund, and J. Lund Novel involvement of a mitochondrial steroid hydroxylase (P450c11) in xenobiotic metabolism J. Biol. Chem. 270 1995 20895 20897
112. M. Johansson, C. Larsson, A. Bergman, and B.O. Lund Structure-activity relationship for inhibition of CYP11B1-dependent glucocorticoid synthesis in Y1 cells by aryl methyl sulfones Pharmacol. Toxicol. 83 1998 225 230
113. N. McKenna, and B.W. O'Malley Nuclear receptors, coregulators, ligands, and selective receptor modulators Ann. N. Y. Acad. Sci. 949 2001 3 5
114. L.P. Freedman Increasing the complexity of coactivation in nuclear receptor signaling Cell 97 1999 5 8
115. C. Rachez, M. Gamble, C.P.B. Chang, G.B. Atkins, M.A. Lazar, and L.P. Freedman The DRIP complex and SRC-1/p160 coactivators share similar nuclear receptor binding determinants but constitute functionally distinct complexes Mol. Cell. Biol. 20 2000 2718 2726
116. D.M. Lonard, S.Y. Tsai, and B.W. O'Malley Selective estrogen receptor modulators 4-hydroxytamoxifen and raloxifene impact the stability and function of SRC-1 and SRC-3 coactivator proteins Mol. Cell. Biol. 24 2004 14 24
117. F. Grun, and B. Blumberg Environmental obesogens: organotins and endocrine disruption via nuclear receptor signaling Endocrinology 147 2006 50 55
118. M. Golub, and J. Doherty Triphenyltin as a potential human endocrine disruptor J. Toxicol. Environ. Health B Crit. Rev. 7 2004 281 295
119. F. Grün, and B. Blumberg Perturbed nuclear receptor signaling by environmental obesogens as emerging factors in the obesity crisis Rev. Endocr. Metab. Disord. 161 2007 161 171
120. L. You, M. Sar, E. Bartolucci, S. Ploch, and et al. Induction of hepatic aromatase by p,p′-DDE in adult male rats Mol. Cell. Endocrinol. 178 2001 207 214
121. M.S. Jansen, S.C. Nagel, P.J. Miranda, E.K. Lobenhofer, and et al. Short-chain fatty acids enhance nuclear receptor activity through mitogen-activated protein kinase activation and histone deacetylase inhibition Proc. Natl. Acad. Sci. 101 2004 7199 7204
122. M.M. Tabb, and B. Blumberg New modes of action for endocrine-disrupting chemicals Mol. Endocrinol. 20 2006 475 482
123. O.M. Tirado, D.M. Selva, N. Toràn, C.A. Suárez-Quian, and et al. Increased expression of estrogen receptor β in pachytene spermatocytes after short-term methoxyacetic acid administration J. Androl. 25 2004 84 94
124. W.R. Kelce, C.R. Lambright, L.E. Gray, and K.O. Roberts Vinclozolin and p, p′-DDE alter androgen-dependent gene expression: in vivo confirmation of an androgen receptor-mediated mechanism Toxicol. Appl. Pharmacol. 142 1997 192 200
125. M.S. Wolff, A. Zeleniuch-Jacquotte, N. Dubin, and P. Toniolo Risk of breast cancer and organochlorine exposure Cancer Epidemiol. Biomarkers Prev. 9 2000 271 277
126. L.E. Braverman, X. He, S. Pino, M. Cross, B. Magnani, S.H. Lamm, and J.P. Gibbs The effect of perchlorate, thiocyanate, and nitrate on thyroid function in workers exposed to perchlorate long-term J. Clin. Endocrinol. Metab. 90 2005 700 706
127. P. Alonso-Magdalena, S. Morimoto, C. Ripoll, E. Fuentes, and A. Nadal The estrogenic effect of bisphenol A disrupts pancreatic β-cell function in vivo and induces insulin resistance Environ. Health Perspect. 2006 106 112