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Volumn 48, Issue 6, 2010, Pages 1439-1447

Interpretation of studies on the developmental reproductive toxicology of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male offspring

Author keywords

Developmental; Dioxin; Reproductive; Spermatogenesis; TCDD; Toxicity

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; PHTHALIC ACID DERIVATIVE;

EID: 77952882102     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2010.04.005     Document Type: Review
Times cited : (27)

References (49)
  • 1
    • 0038493955 scopus 로고    scopus 로고
    • The effect on sperm production in adult Sprague-Dawley rats exposed by gavage to bisphenol a between postnatal days 91-97
    • Ashby J., Tinwell H., Lefevre P.A., Joiner R., Haseman J. The effect on sperm production in adult Sprague-Dawley rats exposed by gavage to bisphenol a between postnatal days 91-97. Toxicol. Sci. 2003, 74:129-138.
    • (2003) Toxicol. Sci. , vol.74 , pp. 129-138
    • Ashby, J.1    Tinwell, H.2    Lefevre, P.A.3    Joiner, R.4    Haseman, J.5
  • 2
    • 27644571239 scopus 로고    scopus 로고
    • Exposure reconstruction for the TCDD-exposed NIOSH cohort using a concentration- and age-dependent model of elimination
    • Aylward L.L., Brunet R.C., Starr T.B., Carrier G., Delzell E., Cheng H., Beall C. Exposure reconstruction for the TCDD-exposed NIOSH cohort using a concentration- and age-dependent model of elimination. Risk Anal. 2005, 25:945-956.
    • (2005) Risk Anal. , vol.25 , pp. 945-956
    • Aylward, L.L.1    Brunet, R.C.2    Starr, T.B.3    Carrier, G.4    Delzell, E.5    Cheng, H.6    Beall, C.7
  • 6
    • 0027956142 scopus 로고
    • Reproductive toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male-rats - different effects of in-utero versus lactational exposure
    • Bjerke D.L., Peterson R.E. Reproductive toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male-rats - different effects of in-utero versus lactational exposure. Toxicol. Appl. Pharmacol. 1994, 127:241-249.
    • (1994) Toxicol. Appl. Pharmacol. , vol.127 , pp. 241-249
    • Bjerke, D.L.1    Peterson, R.E.2
  • 7
    • 0028122411 scopus 로고
    • Effects of in-utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on responsiveness of the male-rat reproductive-system to testosterone stimulation in adulthood
    • Bjerke D.L., Sommer R.J., Moore R.W., Peterson R.E. Effects of in-utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on responsiveness of the male-rat reproductive-system to testosterone stimulation in adulthood. Toxicol. Appl. Pharmacol. 1994, 127:250-257.
    • (1994) Toxicol. Appl. Pharmacol. , vol.127 , pp. 250-257
    • Bjerke, D.L.1    Sommer, R.J.2    Moore, R.W.3    Peterson, R.E.4
  • 8
    • 21744437115 scopus 로고    scopus 로고
    • Critical window of male reproductive tract development in rats following gestational exposure to di-n-butyl phthalate
    • Carruthers C.M., Foster P.M.D. Critical window of male reproductive tract development in rats following gestational exposure to di-n-butyl phthalate. Birth Defects Res. B - Dev. Reprod. Toxicol. 2005, 74:277-285.
    • (2005) Birth Defects Res. B - Dev. Reprod. Toxicol. , vol.74 , pp. 277-285
    • Carruthers, C.M.1    Foster, P.M.D.2
  • 9
    • 68149124914 scopus 로고    scopus 로고
    • Mortality rates among trichlorophenol workers with exposure to 2,3,7, 8-tetrachlorodibenzo-p-dioxin
    • Collins J.J., Bodner K., Aylward L.L., Wilken M., Bodnar C.M. Mortality rates among trichlorophenol workers with exposure to 2,3,7, 8-tetrachlorodibenzo-p-dioxin. Am. J. Epidemiol. 2009, 170:501-506.
    • (2009) Am. J. Epidemiol. , vol.170 , pp. 501-506
    • Collins, J.J.1    Bodner, K.2    Aylward, L.L.3    Wilken, M.4    Bodnar, C.M.5
  • 10
    • 77952881655 scopus 로고    scopus 로고
    • COT, Statement on the tolerable daily intake for dioxins and dioxin-like polychlorinated biphenyls. Comittee on Toxicity of Chemicals in Food, Consumer Products and the Environment. COT/2001/07 ed., COT/2001/07.
    • COT, 2001. Statement on the tolerable daily intake for dioxins and dioxin-like polychlorinated biphenyls. Comittee on Toxicity of Chemicals in Food, Consumer Products and the Environment. COT/2001/07 ed., COT/2001/07.
    • (2001)
  • 11
    • 1242337270 scopus 로고    scopus 로고
    • Evaluation of testicular toxicology: a synopsis and discussion of the recommendations proposed by the society of toxicologic pathology
    • Creasy D.M. Evaluation of testicular toxicology: a synopsis and discussion of the recommendations proposed by the society of toxicologic pathology. Birth Defects Res. B - Dev. Reprod. Toxicol. 2003, 68:408-415.
    • (2003) Birth Defects Res. B - Dev. Reprod. Toxicol. , vol.68 , pp. 408-415
    • Creasy, D.M.1
  • 12
    • 0034743702 scopus 로고    scopus 로고
    • Subchronic exposure of [H-3]-2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in female B6C3F1 mice: relationship of steady-state levels to disposition and metabolism
    • Diliberto J.J., Devito M.J., Ross G.D., Birnbaum L.S. Subchronic exposure of [H-3]-2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in female B6C3F1 mice: relationship of steady-state levels to disposition and metabolism. Toxicol. Sci. 2001, 61:241-255.
    • (2001) Toxicol. Sci. , vol.61 , pp. 241-255
    • Diliberto, J.J.1    Devito, M.J.2    Ross, G.D.3    Birnbaum, L.S.4
  • 13
    • 3242800512 scopus 로고    scopus 로고
    • Physiologically based pharmacokinetic model for developmental exposures to TCDD in the rat
    • Emond C., Birnbaum L.S., Devito M.J. Physiologically based pharmacokinetic model for developmental exposures to TCDD in the rat. Toxicol. Sci. 2004, 80:115-133.
    • (2004) Toxicol. Sci. , vol.80 , pp. 115-133
    • Emond, C.1    Birnbaum, L.S.2    Devito, M.J.3
  • 14
    • 0034103008 scopus 로고    scopus 로고
    • Sensitivity analysis of a physiological model for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): assessing the impact of specific model parameters on sequestration in liver and fat in the rat
    • Evans M.V., Andersen M.E. Sensitivity analysis of a physiological model for 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): assessing the impact of specific model parameters on sequestration in liver and fat in the rat. Toxicol. Sci. 2000, 54:71-80.
    • (2000) Toxicol. Sci. , vol.54 , pp. 71-80
    • Evans, M.V.1    Andersen, M.E.2
  • 15
    • 0032103386 scopus 로고    scopus 로고
    • Reproductive toxicity and tissue concentrations of low doses of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male offspring rats exposed throughout pregnancy and lactation
    • Faqi A.S., Dalsenter P.R., Merker H.J., Chahoud I. Reproductive toxicity and tissue concentrations of low doses of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male offspring rats exposed throughout pregnancy and lactation. Toxicol. Appl. Pharmacol. 1998, 150:383-392.
    • (1998) Toxicol. Appl. Pharmacol. , vol.150 , pp. 383-392
    • Faqi, A.S.1    Dalsenter, P.R.2    Merker, H.J.3    Chahoud, I.4
  • 16
    • 0028916903 scopus 로고
    • Exposure to TCDD during development permanently alters reproductive function in male long-evans rats and hamsters - reduced ejaculated and epididymal sperm numbers and sex accessory-gland weights in offspring with normal androgenic status
    • Gray L.E., Kelce W.R., Monosson E., Ostby J.S., Birnbaum L.S. Exposure to TCDD during development permanently alters reproductive function in male long-evans rats and hamsters - reduced ejaculated and epididymal sperm numbers and sex accessory-gland weights in offspring with normal androgenic status. Toxicol. Appl. Pharmacol. 1995, 131:108-118.
    • (1995) Toxicol. Appl. Pharmacol. , vol.131 , pp. 108-118
    • Gray, L.E.1    Kelce, W.R.2    Monosson, E.3    Ostby, J.S.4    Birnbaum, L.S.5
  • 17
    • 0029117772 scopus 로고
    • In-utero 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) alters reproductive morphology and function in female rat offspring
    • Gray L.E., Ostby J.S. In-utero 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) alters reproductive morphology and function in female rat offspring. Toxicol. Appl. Pharmacol. 1995, 133:285-294.
    • (1995) Toxicol. Appl. Pharmacol. , vol.133 , pp. 285-294
    • Gray, L.E.1    Ostby, J.S.2
  • 18
    • 0342601484 scopus 로고    scopus 로고
    • A dose-response analysis of the reproductive effects of a single gestational dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male Long Evans Hooded rat offspring
    • Gray L.E., Ostby J.S., Kelce W.R. A dose-response analysis of the reproductive effects of a single gestational dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male Long Evans Hooded rat offspring. Toxicol. Appl. Pharmacol. 1997, 146:11-20.
    • (1997) Toxicol. Appl. Pharmacol. , vol.146 , pp. 11-20
    • Gray, L.E.1    Ostby, J.S.2    Kelce, W.R.3
  • 19
    • 52949122185 scopus 로고    scopus 로고
    • Mechanisms of action of phthalate esters, individually and in combination, to induce abnormal reproductive development in male laboratory rats
    • Howdeshell K.L., Rider C.V., Wilson V.S., Gray L.E. Mechanisms of action of phthalate esters, individually and in combination, to induce abnormal reproductive development in male laboratory rats. Environ. Res. 2008, 108:168-176.
    • (2008) Environ. Res. , vol.108 , pp. 168-176
    • Howdeshell, K.L.1    Rider, C.V.2    Wilson, V.S.3    Gray, L.E.4
  • 20
    • 0033794989 scopus 로고    scopus 로고
    • Tissue disposition of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in maternal and developing Long-Evans rats following subchronic exposure
    • Hurst C.H., Devito M.J., Birnbaum L.S. Tissue disposition of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in maternal and developing Long-Evans rats following subchronic exposure. Toxicol. Sci. 2000, 57:275-283.
    • (2000) Toxicol. Sci. , vol.57 , pp. 275-283
    • Hurst, C.H.1    Devito, M.J.2    Birnbaum, L.S.3
  • 21
    • 0033952518 scopus 로고    scopus 로고
    • Acute administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in pregnant Long Evans rats: association of measured tissue concentrations with developmental effects
    • Hurst C.H., Devito M.J., Setzer R.W., Birnbaum L.S. Acute administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in pregnant Long Evans rats: association of measured tissue concentrations with developmental effects. Toxicol. Sci. 2000, 53:411-420.
    • (2000) Toxicol. Sci. , vol.53 , pp. 411-420
    • Hurst, C.H.1    Devito, M.J.2    Setzer, R.W.3    Birnbaum, L.S.4
  • 22
    • 22544445566 scopus 로고    scopus 로고
    • Repeated in utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure affects male gonads in offspring, leading to sex ratio changes in F-2 progeny
    • Ikeda M., Tamura M., Yamashita J., Suzuki C., Tomita T. Repeated in utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure affects male gonads in offspring, leading to sex ratio changes in F-2 progeny. Toxicol. Appl. Pharmacol. 2005, 206:351-355.
    • (2005) Toxicol. Appl. Pharmacol. , vol.206 , pp. 351-355
    • Ikeda, M.1    Tamura, M.2    Yamashita, J.3    Suzuki, C.4    Tomita, T.5
  • 23
    • 77952875376 scopus 로고    scopus 로고
    • JECFA, Evaluation of certain food additives and contaminants (57th report of the Joint FAO/WHO Expert Committee on Food Additives). WHO Tech. Rep. Ser. 909, 121-149.
    • JECFA, 2002. Evaluation of certain food additives and contaminants (57th report of the Joint FAO/WHO Expert Committee on Food Additives). WHO Tech. Rep. Ser. 909, 121-149.
    • (2002)
  • 25
    • 0030977083 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and congeners in infants. A toxicokinetic model of human lifetime body burden by TCDD with special emphasis on its uptake by nutrition
    • Kreuzer P.E., Csanady G.A., Baur C., Kessler W., Papke O., Greim H., Filser J.G. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and congeners in infants. A toxicokinetic model of human lifetime body burden by TCDD with special emphasis on its uptake by nutrition. Arch. Toxicol. 1997, 71:383-400.
    • (1997) Arch. Toxicol. , vol.71 , pp. 383-400
    • Kreuzer, P.E.1    Csanady, G.A.2    Baur, C.3    Kessler, W.4    Papke, O.5    Greim, H.6    Filser, J.G.7
  • 27
    • 33645646302 scopus 로고    scopus 로고
    • Elimination half-lives of selected polychlorinated dibenzodioxins and dibenzofurans in breast-fed human infants
    • Leung H.W., Kerger B.D., Paustenbach D.J. Elimination half-lives of selected polychlorinated dibenzodioxins and dibenzofurans in breast-fed human infants. J. Toxicol. Environ. Health A 2006, 69:437-443.
    • (2006) J. Toxicol. Environ. Health A , vol.69 , pp. 437-443
    • Leung, H.W.1    Kerger, B.D.2    Paustenbach, D.J.3
  • 28
    • 0026755842 scopus 로고
    • In utero and lactational exposure of male-rats to 2,3,7,8-tetrachlorodibenzo-para-dioxin. 3. Effects on spermatogenesis and reproductive capability
    • Mably T.A., Bjerke D.L., Moore R.W., GendronFitzpatrick A., Peterson R.E. In utero and lactational exposure of male-rats to 2,3,7,8-tetrachlorodibenzo-para-dioxin. 3. Effects on spermatogenesis and reproductive capability. Toxicol. Appl. Pharmacol. 1992, 114:118-126.
    • (1992) Toxicol. Appl. Pharmacol. , vol.114 , pp. 118-126
    • Mably, T.A.1    Bjerke, D.L.2    Moore, R.W.3    GendronFitzpatrick, A.4    Peterson, R.E.5
  • 29
    • 0026755841 scopus 로고
    • In utero and lactational exposure of male-rats to 2,3,7,8-tetrachlorodibenzo-para-dioxin. 2. Effects on sexual-behavior and the regulation of luteinizing-hormone secretion in adulthood
    • Mably T.A., Moore R.W., Goy R.W., Peterson R.E. In utero and lactational exposure of male-rats to 2,3,7,8-tetrachlorodibenzo-para-dioxin. 2. Effects on sexual-behavior and the regulation of luteinizing-hormone secretion in adulthood. Toxicol. Appl. Pharmacol. 1992, 114:108-117.
    • (1992) Toxicol. Appl. Pharmacol. , vol.114 , pp. 108-117
    • Mably, T.A.1    Moore, R.W.2    Goy, R.W.3    Peterson, R.E.4
  • 30
    • 0026736617 scopus 로고
    • In utero and lactational exposure of male-rats to 2,3,7,8-tetrachlorodibenzo-para-dioxin. 1. Effects on androgenic status
    • Mably T.A., Moore R.W., Peterson R.E. In utero and lactational exposure of male-rats to 2,3,7,8-tetrachlorodibenzo-para-dioxin. 1. Effects on androgenic status. Toxicol. Appl. Pharmacol. 1992, 114:97-107.
    • (1992) Toxicol. Appl. Pharmacol. , vol.114 , pp. 97-107
    • Mably, T.A.1    Moore, R.W.2    Peterson, R.E.3
  • 31
    • 0031860360 scopus 로고    scopus 로고
    • Male reproductive tract malformations in rats following gestational and lactational exposure to di(n-butyl) phthalate: an antiandrogenic mechanism?
    • Mylchreest E., Cattley R.C., Foster P.M.D. Male reproductive tract malformations in rats following gestational and lactational exposure to di(n-butyl) phthalate: an antiandrogenic mechanism?. Toxicol. Sci. 1998, 43:47-60.
    • (1998) Toxicol. Sci. , vol.43 , pp. 47-60
    • Mylchreest, E.1    Cattley, R.C.2    Foster, P.M.D.3
  • 32
    • 0038408989 scopus 로고    scopus 로고
    • Rat thyroid hyperplasia induced by gestational and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Nishimura N., Yonemoto J., Miyabara Y., Sato M., Tohyama C. Rat thyroid hyperplasia induced by gestational and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Endocrinology 2003, 144:2075-2083.
    • (2003) Endocrinology , vol.144 , pp. 2075-2083
    • Nishimura, N.1    Yonemoto, J.2    Miyabara, Y.3    Sato, M.4    Tohyama, C.5
  • 33
    • 18144370812 scopus 로고    scopus 로고
    • Disruption of thyroid hormone homeostasis at weaning of Holtzman rats by lactational but not in utero exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Nishimura N., Yonemoto J., Nishimura H., Ikushiro S., Tohyama C. Disruption of thyroid hormone homeostasis at weaning of Holtzman rats by lactational but not in utero exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol. Sci. 2005, 85:607-614.
    • (2005) Toxicol. Sci. , vol.85 , pp. 607-614
    • Nishimura, N.1    Yonemoto, J.2    Nishimura, H.3    Ikushiro, S.4    Tohyama, C.5
  • 34
    • 33748742261 scopus 로고    scopus 로고
    • Localization of cytochrome P450 1A1 in a specific region of hydronephrotic kidney of rat neonates lactationally exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Nishimura N., Yonemoto J., Nishimura H., Tohyama C. Localization of cytochrome P450 1A1 in a specific region of hydronephrotic kidney of rat neonates lactationally exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicology 2006, 227:117-126.
    • (2006) Toxicology , vol.227 , pp. 117-126
    • Nishimura, N.1    Yonemoto, J.2    Nishimura, H.3    Tohyama, C.4
  • 35
    • 17744400089 scopus 로고    scopus 로고
    • Maternal exposure to a low dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) suppressed the development of reproductive organs of male rats: dose-dependent increase of mRNA levels of 5 alpha-reductase type 2 in contrast to decrease of androgen receptor in the pubertal ventral prostate
    • Ohsako S., Miyabara Y., Nishimura N., Kurosawa S., Sakaue M., Ishimura R., Sato M., Takeda K., Aoki Y., Sone H., Tohyama C., Yonemoto J. Maternal exposure to a low dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) suppressed the development of reproductive organs of male rats: dose-dependent increase of mRNA levels of 5 alpha-reductase type 2 in contrast to decrease of androgen receptor in the pubertal ventral prostate. Toxicol. Sci. 2001, 60:132-143.
    • (2001) Toxicol. Sci. , vol.60 , pp. 132-143
    • Ohsako, S.1    Miyabara, Y.2    Nishimura, N.3    Kurosawa, S.4    Sakaue, M.5    Ishimura, R.6    Sato, M.7    Takeda, K.8    Aoki, Y.9    Sone, H.10    Tohyama, C.11    Yonemoto, J.12
  • 36
    • 0036208501 scopus 로고    scopus 로고
    • Developmental stage-specific effects of perinatal 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on reproductive organs of male rat offspring
    • Ohsako S., Miyabara Y., Sakaue M., Ishimura R., Kakeyama M., Izumi H., Yonemoto J., Tohyama C. Developmental stage-specific effects of perinatal 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on reproductive organs of male rat offspring. Toxicol. Sci. 2002, 66:283-292.
    • (2002) Toxicol. Sci. , vol.66 , pp. 283-292
    • Ohsako, S.1    Miyabara, Y.2    Sakaue, M.3    Ishimura, R.4    Kakeyama, M.5    Izumi, H.6    Yonemoto, J.7    Tohyama, C.8
  • 37
    • 0020010617 scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-para-dioxin and related halogenated aromatic-hydrocarbons - examination of the mechanism of toxicity
    • Poland A., Knutson J.C. 2,3,7,8-Tetrachlorodibenzo-para-dioxin and related halogenated aromatic-hydrocarbons - examination of the mechanism of toxicity. Annu. Rev. Pharmacol. Toxicol. 1982, 22:517-554.
    • (1982) Annu. Rev. Pharmacol. Toxicol. , vol.22 , pp. 517-554
    • Poland, A.1    Knutson, J.C.2
  • 38
    • 0024475204 scopus 로고
    • [I-125]2-Iodo-3,7,8-Trichlorodibenzo-p-dioxin-binding species in mouse-liver induced by agonists for the ah receptor - characterization and identification
    • Poland A., Teitelbaum P., Glover E. [I-125]2-Iodo-3,7,8-Trichlorodibenzo-p-dioxin-binding species in mouse-liver induced by agonists for the ah receptor - characterization and identification. Mol. Pharmacol. 1989, 36:113-120.
    • (1989) Mol. Pharmacol. , vol.36 , pp. 113-120
    • Poland, A.1    Teitelbaum, P.2    Glover, E.3
  • 39
    • 0024328776 scopus 로고
    • Stimulation of in vivo hepatic uptake and invitro hepatic binding of [i-125]2-iodo-3,7,8-trichlorodibenzo-p-dioxin by the administration of agonists for the Ah receptor
    • Poland A., Teitelbaum P., Glover E., Kende A. Stimulation of in vivo hepatic uptake and invitro hepatic binding of [i-125]2-iodo-3,7,8-trichlorodibenzo-p-dioxin by the administration of agonists for the Ah receptor. Mol. Pharmacol. 1989, 36:121-127.
    • (1989) Mol. Pharmacol. , vol.36 , pp. 121-127
    • Poland, A.1    Teitelbaum, P.2    Glover, E.3    Kende, A.4
  • 40
    • 0028849927 scopus 로고
    • In-utero and lactational exposure of the male-rat to 2,3,7,8-tetrachlorodibenzo-p-dioxin - impaired prostate growth and development without inhibited androgen production
    • Roman B.L., Sommer R.J., Shinomiya K., Peterson R.E. In-utero and lactational exposure of the male-rat to 2,3,7,8-tetrachlorodibenzo-p-dioxin - impaired prostate growth and development without inhibited androgen production. Toxicol. Appl. Pharmacol. 1995, 134:241-250.
    • (1995) Toxicol. Appl. Pharmacol. , vol.134 , pp. 241-250
    • Roman, B.L.1    Sommer, R.J.2    Shinomiya, K.3    Peterson, R.E.4
  • 41
  • 42
    • 77952878366 scopus 로고    scopus 로고
    • SCF, Opinion of the Scientific Committee On Food on the risk assessment of dioxins and dioxin-like pcbs in food. Update based on new scientific information available since the adoption of the SCF opinion of 22nd November 2000. Adopted on 30 May 2001.
    • SCF, 2001. Opinion of the Scientific Committee On Food on the risk assessment of dioxins and dioxin-like pcbs in food. Update based on new scientific information available since the adoption of the SCF opinion of 22nd November 2000. Adopted on 30 May 2001.
    • (2001)
  • 43
    • 3242789451 scopus 로고    scopus 로고
    • Pattern of male reproductive system effects after in utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure in three differentially TCDD-sensitive rat lines
    • Simanainen U., Haavisto T., Tuomisto J.T., Paranko J., Toppari J., Tuomisto J., Peterson R.E., Viluksela M. Pattern of male reproductive system effects after in utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure in three differentially TCDD-sensitive rat lines. Toxicol. Sci. 2004, 80:101-108.
    • (2004) Toxicol. Sci. , vol.80 , pp. 101-108
    • Simanainen, U.1    Haavisto, T.2    Tuomisto, J.T.3    Paranko, J.4    Toppari, J.5    Tuomisto, J.6    Peterson, R.E.7    Viluksela, M.8
  • 44
    • 0030248054 scopus 로고    scopus 로고
    • In utero and lactational exposure of the male Holtzman rat to 2, 3,7,8-tetrachlorodibenzo-p-dioxin: decreased epididymal and ejaculated sperm numbers without alterations in sperm transit rate
    • Sommer R.J., Ippolito D.L., Peterson R.E. In utero and lactational exposure of the male Holtzman rat to 2, 3,7,8-tetrachlorodibenzo-p-dioxin: decreased epididymal and ejaculated sperm numbers without alterations in sperm transit rate. Toxicol. Appl. Pharmacol. 1996, 140:146-153.
    • (1996) Toxicol. Appl. Pharmacol. , vol.140 , pp. 146-153
    • Sommer, R.J.1    Ippolito, D.L.2    Peterson, R.E.3
  • 45
    • 77957175125 scopus 로고
    • Tissue distribution and toxicokinetics of 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats after intravenous-injection
    • Weber L.W.D., Ernst S.W., Stahl B.U., Rozman K. Tissue distribution and toxicokinetics of 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats after intravenous-injection. Fund. Appl. Toxicol. 1993, 21:523-534.
    • (1993) Fund. Appl. Toxicol. , vol.21 , pp. 523-534
    • Weber, L.W.D.1    Ernst, S.W.2    Stahl, B.U.3    Rozman, K.4
  • 46
    • 0014772440 scopus 로고
    • Selection of valid number of sampling units and a consideration of their combination in toxicological studies involving reproduction, teratogenesis or carcinogenesis
    • Weil C.S. Selection of valid number of sampling units and a consideration of their combination in toxicological studies involving reproduction, teratogenesis or carcinogenesis. Food Cosmet. Toxicol. 1970, 8:177-182.
    • (1970) Food Cosmet. Toxicol. , vol.8 , pp. 177-182
    • Weil, C.S.1
  • 47
    • 41849107583 scopus 로고    scopus 로고
    • Identification in rats of a programming window for reproductive tract masculinization, disruption of which leads to hypospadias and cryptorchidism
    • Welsh M., Saunders P.T.K., Fisken M., Scott H.M., Hutchison G.R., Smith L.B., Sharpe R.M. Identification in rats of a programming window for reproductive tract masculinization, disruption of which leads to hypospadias and cryptorchidism. J. Clin. Invest. 2008, 118:1479-1490.
    • (2008) J. Clin. Invest. , vol.118 , pp. 1479-1490
    • Welsh, M.1    Saunders, P.T.K.2    Fisken, M.3    Scott, H.M.4    Hutchison, G.R.5    Smith, L.B.6    Sharpe, R.M.7
  • 48
    • 0030296968 scopus 로고    scopus 로고
    • Effects of developmental exposure to indole-3-carbinol or 2,3,7,8-tetrachlorodibenzo-p-dioxin on reproductive potential of male rat offspring
    • Wilker C., Johnson L., Safe S. Effects of developmental exposure to indole-3-carbinol or 2,3,7,8-tetrachlorodibenzo-p-dioxin on reproductive potential of male rat offspring. Toxicol. Appl. Pharmacol. 1996, 141:68-75.
    • (1996) Toxicol. Appl. Pharmacol. , vol.141 , pp. 68-75
    • Wilker, C.1    Johnson, L.2    Safe, S.3
  • 49
    • 14544267745 scopus 로고    scopus 로고
    • Maternal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin and the body burden in offspring of Long-Evans rats
    • Yonemoto J., Ichiki T., Takei T., Tohyama C. Maternal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin and the body burden in offspring of Long-Evans rats. Environ. Health Prev. Med. 2005, 10:21-32.
    • (2005) Environ. Health Prev. Med. , vol.10 , pp. 21-32
    • Yonemoto, J.1    Ichiki, T.2    Takei, T.3    Tohyama, C.4


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