Endocrine disruptors and reproductive health: The case of bisphenol-A

Molecular and Cellular Endocrinology

Volumn 254-255, Issue , 2006, Pages 179-186

  Maffini, Maricel V ^a   Rubin, Beverly S ^a   Sonnenschein, Carlos ^a   Soto, Ana M ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bisphenol A; Breast cancer; Estrous cycles; Genital tract; Mammary gland development; Xenoestrogens

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; BIOMEDICAL AND DENTAL MATERIALS; ENDOCRINE DISRUPTOR; EPOXY RESIN; ESTROGEN; HORMONE; PLASTIC; POLYCARBONATE; XENOBIOTIC AGENT;

ARTICLE; BEVERAGE; BODY WEIGHT; BREAST CANCER; BREAST DISEASE; CHEMICAL MODEL; CONGENITAL MALFORMATION; CONTAINER; DEVELOPMENT; DISEASE PREDISPOSITION; DOSIMETRY; ENDOCRINE SYSTEM; ENVIRONMENTAL EXPOSURE; EPIDEMIOLOGICAL DATA; ESTROGEN ACTIVITY; FEMALE GENITAL SYSTEM; FEMALE GENITAL TRACT MALFORMATION; FOOD; FUNCTIONAL DISEASE; HUMAN; INCIDENCE; INFERTILITY; MALE GENITAL SYSTEM; MALE GENITAL TRACT MALFORMATION; MAMMARY GLAND; MORPHOLOGY; NONHUMAN; ONSET AGE; OOCYTE; OVARY; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROSTATE CANCER; PUBERTY; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; REPRODUCTION; REPRODUCTIVE HEALTH; REPRODUCTIVE TOXICITY; SPERM; TERATOGENICITY; TESTIS CANCER; TIME; WILDLIFE;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCRINE DISRUPTORS; ENVIRONMENTAL EXPOSURE; FETAL DEVELOPMENT; HUMANS; PHENOLS; REPRODUCTION;

EID: 33745899960     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2006.04.033     Document Type: Article

References (65)

1. Arakawa C., Fujimaki K., Yoshinaga J., Imai H., Serizawa S., and Shiraishi H. Daily urinary excretion of bisphenol A. Environ. Health Prev. Med. 9 (2004) 22-26
2. Berkner S., Streck G., and Herrmann R. Development and validation of a method for determination of trace levels of alkylphenols and bisphenol A in atmospheric samples. Chemosphere 54 4 (2004) 575-584
3. Biles J.E., McNeal T.P., Begley T.H., and Hollifield H.C. Determination of bisphenol-A in reusable polycarbonate food-contact plastics and migration to food simulating liquids. J. Agric. Food Chem. 45 (1997) 3541-3544
4. Blank H.M., Marcus M., Tolbert P.E., Rubin C., Henderson A.K., Hertzberg V.S., Zhang R.H., and Cameron L. Age at menarche and tanner stage in girls exposed in utero and postnatally to polybrominated biphenyl. Epidemiology 11 (2000) 641-647
5. Bourguignon J.-P., et al. Presented at the Sixth Puberty Conference. Evian, France, October 2005 (2005)
6. Brotons J.A., Olea-Serrano M.F., Villalobos M., and Olea N. Xenoestrogens released from lacquer coating in food cans. Environ. Health Perspect. 103 (1994) 608-612
7. Calafat A.M., Kuklenyik Z., Reidy J.A., Caudill S.P., Ekong J., and Needham J.L. Urinary concentrations of bisphenol A and 4-nonylphenol in a human reference population. Environ. Health Perspect. 113 (2005) 391-395
8. Carlsen E., Giwercman A., Keinding N., and Skakkebaek N.E. Evidence for the decreasing quality of semen during the past 50 years. Br. Med. J. 305 (1992) 609-612
9. Cohn B., Wolff M., Cirillo P., Sholtz R., Christianson R., van den Berg B., and Siiteri K. Timing of DDT exposure and breast cancer before age 50. Proceedings of the International Society for Environmental Epidemiology. Epidemiology 13 (2002) S197
10. Couse J.F., Davis V.L., Hanson R.B., Jefferson W.N., McLachlan J.A., Bullock B.C., Newbold R.R., and Korach K.S. Accelerated onset of uterine tumors in transgenic mice with aberrant expression of the estrogen receptor after neonatal exposure to diethylstilbestrol. Mol. Carcinog. 19 (1997) 236-242
11. De Vries G.J., and Simerly R.B. Sexually dimorphic neural circuits in the mammalian brain. In: Pfaff D.W., Arnold A.P., Etgen A.M., Fahrbach S.E., and Rubin R.T. (Eds). Hormones, Brain and Behavior (2002), Elsevier, New York 137
12. del Rio Gomez I., Marshall T., Tsai P., Shao Y.-S., and Guo Y.L. Number of boys born to men exposed to polychlorinated byphenyls. Lancet 360 (2002) 143-144
13. Doerge D.R., and Sheehan D.M. Goitrogenic and estrogenic activity of soy isoflavones. Environ. Health Perspect. 110 Suppl. (2002) 349-353
14. Funabashi T., Kawaguchi M., Furuta M., Fukushima A., and Kimura F. Exposure to bisphenol A during gestation and lactation causes loss of sex difference in corticotropin-releasing hormone-immunoreactive neurons in the bed nucleus of the stria terminalis of rats. Psychoneuroendocrinology 29 (2004) 475-485
15. Gilbert S.F., and Sarkar S. Embracing complexity: Organicism for the 21st century. Dev. Dyn. 219 (2000) 1-9
16. Giwercman A., Carlsen E., Keiding N., and Skakkebaek N.E. Evidence for increasing incidence of abnormalities of the human testis: a review. Environ. Health Perspect. 101 (1993) 65-71
17. Gray G.M., Cohen J.T., Cunha G., Hughes C., McConnell E.E., Rhomberg L., et al. Weight of the evidence: evaluation of low-dose reproductive and developmental effects of bisphenol A. Hum. Ecol. Risk Assess. 10 (2004) 875-921
18. Gray Jr. L.E., and Foster P.M.D. Significance of experimental studies for assessing adverse effects of endocrine-disrupting chemicals. Pure Appl. Chem. 75 (2003) 2125-2141
19. Gupta M.S. Reproductive malformation of the male offspring following maternal exposure to estrogenic chemicals. Proc. Soc. Exp. Biol. Med. 224 (2000) 61-68
20. Hassold T., and Hunt P. To err (meiotically) is human: the genesis of human aneuploidy. Nat. Rev. Genet. 2 (2001) 280-291
21. Howdeshell K.L., Hotchkiss A.K., Thayer K.A., Vandenbergh J.G., and vom Saal F.S. Exposure to bisphenol A advances puberty. Nature 401 (1999) 763-764
22. Hunt P.A., Koehler K.E., Susiarjo M., Hodges C.A., Ilagan A., Voigt R.C., Thomas S., Thomas B.F., and Hassold T.J. Bisphenol A exposure causes meiotic aneuploidy in the female mouse. Curr. Biol. 13 (2003) 546-553
23. Ibarluzea J.M., Fernández M.F., Santa-Marina L., Olea-Serrano M.F., Rivas A.M., Aurrekoetxea J.J., Expósito J., Lorenzo M., Torné P., Villalobos M., Pedraza V., Sasco A.J., and Olea N. Breast cancer risk in the combined effect of environmental estrogens. CCC 15 (2004) 591-600
24. Ikezuki Y., Tsutsumi O., Takai Y., Kamei Y., and Taketani Y. Determination of bisphenol A concentrations in human biological fluids reveals significant early prenatal exposure. Hum. Reprod. 17 (2002) 2839-2841
25. Kato H., Furuhashi T., Tanaka M., Katsu Y., Watanabe H., Ohta Y., and Iguchi T. Effects of bisphenol A given neonatally on reproductive functions of male rats. Reprod. Toxicol. November 32 (2005) (ONLINE. PMID: 16311018)
26. Krishnan A.V., Starhis P., Permuth S.F., Tokes L., and Feldman D. Bisphenol-A: an estrogenic substance is released from polycarbonate flasks during autoclaving. Endocrinology 132 (1993) 2279-2286
27. Kubo K., Arai O., Omura M., Watanabe R., Ogata R., and Aou S. Low dose effects of bisphenol A on sexual differentiation of the brain and behavior in rats. Neurosci. Res. 45 (2003) 345-356
28. Kuiper G.G.J.M., Lemmen J.G., Carlsson B., Corton J.C., Safe S.H., Van Der Saag P.T., van der Burg B., and Gustafsson J. Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta. Endocrinology 139 (1998) 4252-4263
29. Land C.E., Tokunaga M., Koyama K., Soda M., Preston D.L., Nishimori I., and Tokuoka S. Incidence of female breast cancer among atomic bomb survivors, Hiroshima and Nagasaki, 1950-1990. Radiat. Res. 160 (2003) 707-717
30. Lemos-Marini S.H., et al. Presented at the Sixth Puberty Conference. Evian, France, October 2005 (2005)
31. Markey C.M., Coombs M.A., Sonnenschein C., and Soto A.M. Mammalian development in a changing environment: exposure to endocrine disruptors reveals the developmental plasticity of steroid-hormone target organs. Evol. Dev. 5 (2003) 1-9
32. Markey C.M., Luque E.H., Munoz de Toro M.M., Sonnenschein C., and Soto A.M. In utero exposure to bisphenol A alters the development and tissue organization of the mouse mammary gland. Biol. Reprod. 65 (2001) 1215-1223
33. Markey C.M., Michaelson C.L., Sonnenschein C., and Soto A.M. Alkylphenols and bisphenol A as environmental estrogens. In: Metzler M. (Ed). The Handbook of Environmental Chemistry. Part L, Endocrine Disruptors-Part I vol. 3 (2001), Springer-Verlag, Berlin Heidelberg 129-153
34. Markey C.M., Wadia P.R., Rubin B.S., Sonnenschein C., and Soto A.M. Long-term effects of fetal exposure to low doses of the xenoestrogen bisphenol-A in the female mouse genital tract. Biol. Reprod. 72 (2005) 1344-1351
35. Masutomi N., Shibutani M., Takagi H., Uneyama C., Lee K.Y., and Hirose M. Alteration of pituitary hormone-immunoreactive cell populations in rat offspring after maternal dietary exposure to endocrine-active chemicals. Arch. Toxicol. 78 (2004) 232-240
36. Matsumoto H., Adachi S., and Suzuki Y. Bisphenol A in ambient air particulates responsible for the proliferation of MCF-7 human breast caner cells and its concentration changes over 6 months. Arch. Environ. Contam. Toxicol. 48 4 (2005) 459-466
37. McEwen B.S., and Alves S.E. Estrogen actions in the central nervous system. Endocr. Rev. 20 (1999) 279-307
38. Munoz de Toro M.M., Markey C.M., Wadia P.R., Luque E.H., Rubin B.S., Sonnenschein C., and Soto A.M. Perinatal exposure to Bisphenol A alters peripubertal mammary gland development in mice. Endocrinology 146 (2005) 4138-4147
39. NTP, 2001. National Toxicology Program's Report of the Endocrine Disruptors Low Dose Peer Review. National Toxicology Program, Research Triangle Park, NC. Available: http://ntp.niehs.nih.gov/ntp/htdocs/liason/LowDosePeerFinalRpt.pdf, accessed March 5, 2006.
40. Olea N., Pulgar R., Perez P., Olea-Serrano F., Rivas A., Novillo-Fertrell A., Pedraza V., Soto A.M., and Sonnenschein C. Estrogenicity of resin-based composites and sealants used in dentistry. Environ. Health Perspect. 104 3 (1996) 298-305
41. Ong K., et al. Presented at the Sixth Puberty Conference. Evian, France, October 2005 (2005)
42. Petersen S.L., and Barraclough C.A. Suppression of spontaneous LH surges in estrogen-treated ovariectomized rats by microimplants of antiestrogens into the preoptic brain. Brain Res. 484 (1989) 279-289
43. Petersen S.L., Ottem E.N., and Carpenter C.D. Direct and indirect regulation of gonadotropin-releasing hormone neurons by estradiol. Biol. Reprod. 69 (2003) 1771-1778
44. Ramos J.G., Varayoud J., Sonnenschein C., Soto A.M., Munoz de Toro M.M., and Luque E.H. Prenatal exposure to low doses of bisphenol A alters the periductal stroma and glandular cell function in the rat ventral prostate. Biol. Reprod. 65 (2001) 1271-1277
45. In: Ries L.A.G., Eisner M.P., Kosary C.L., Hankey B.F., Miller B.A., Clegg L., and Edwards B.K. (Eds). SEER Cancer Statistics Review (1973-1999 (2002)), National Cancer Institute, Bethesda, MD
46. Rodrigues-Mozaz S., Lopez de Alda M., and Barcelo D. Analysis of bisphenol A in natural waters by means of an optical immunosensor. Water Res. 39 (2005) 5071-5079
47. Rubin B.S., Murray M.K., Damassa D.A., King J.C., and Soto A.M. Perinatal exposure to low doses of bisphenol-A affects body weight, patterns of estrous cyclicity and plasma LH levels. Environ. Health Perspect. 109 (2001) 675-680
48. Russo J., and Russo I.H. DNA labeling index and structure of the rat mammary gland as determinants of its susceptibility to carcinogenesis. J. Nat. Cancer Inst. 61 (1978) 1451-1459
49. Schonfelder G., Flick B., Mayr E., Talsness C., Paul M., and Chahoud I. In utero exposure to low doses of bisphenol A lead to long-term deleterious effects in the vagina. Neoplasia 4 (2002) 98-102
50. Simonian S.X., Spratt D.P., and Herbison A.E. Identification and characterization of estrogen receptor a-containing neurons projecting to the vicinity of the gonadotropin-releasing hormone perikarya in the rostral preoptic area of the rat. J. Comp. Neurol. 411 (1999) 346-358
51. Skynner M.J., Sim J.A., and Herbison A.E. Detection of estrogen receptor alpha and beta messenger ribonucleic acids in adult gonadotropin-releasing hormone neurons. Endocrinology 140 (2000) 5195-5201
52. Sonnenschein C., Soto A.M., Fernandez M.F., Olea N., Olea-Serrano M.F., and Ruiz-Lopez M.D. Development of a marker of estrogenic exposure in human serum. Clin. Chem. 41 (1995) 1888-1895
53. Soto A.M., Fernandez M.F., Luizzi M.F., Oles Karasko A.S., and Sonnenschein C. Developing a marker of exposure to xenoestrogen mixtures in human serum. Environ. Health Perspect. 105 (1997) 647-654
54. Soto A.M., and Sonnenschein C. Emergentism as a default: cancer as a problem of tissue organization. J. Biosci. 30 (2005) 103-118
55. Sugiura-Ogasawara M., Ozaki Y., Sonta S.-I., Makino T., and Suzumori K. Exposure to bisphenol A is associated with recurrent miscarriage. Hum. Reprod. 20 (2005) 2325-2329
56. Sun Y., Irie M., Kishikawa N., Wada M., Kuroda N., and Nakashima K. Determination of bisphenol A in human breast milk by HPLC with column-switching and fluorescence detection. Biomed. Chromatogr. 18 (2004) 501-507
57. Swan S.H., Main K.M., Liu F., Stewart S.L., Kruse R.L., Calafat A.M., Mao C.S., Redmon J.B., Ternand C.L., Sullivan S., Teague J.L., and the Study for Future Families Research Team. Decrease in anogenital distance among male infants with prenatal phthalate exposure. Environ. Health Perspect. 113 (2005) 1056-1061
58. Takeuchi T., and Tsutsumi O. Serum bisphenol A concentrations showed gender differences, possibly linked to androgen levels. Biochem. Biophys. Res. Commun. 291 (2002) 76-78
59. Teilmann G., et al. Presented at the Sixth Puberty Conference. Evian, France, October 2005 (2005)
60. Timms B.G., Howdeshell K.L., Barton L., Bradley S., Richter C.A., and vom Saal F.S. Estrogenic chemicals in plastic and oral contraceptives disrupt development of the fetal mouse prostate and urethra. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 7014-7019
61. Tyl R.W., Myers C.B., Marr M.C., Thomas B.F., Keimowitz A.R., Brine D.R., Veselica M.M., Fail P.A., Chang T.Y., Seely J.C., Joiner R.L., Butala J.H., Dimond S.S., Cagen S.Z., Shiotsuka R.N., Stropp G.D., and Waechter J.M. Three-generation reproductive toxicity study of dietary bisphenol A in CD Sprague-Dawley rats. Toxicol. Sci. 68 (2002) 121-146
62. vom Saal F.S., Cooke P.S., Buchanan D.L., Palanza P., Thayer K.A., Nagel S.C., Parmigiani S., and Welshons W.V. A physiologically based approach to the study of bisphenol A and other estrogenic chemicals on the size of reproductive organs, daily sperm production, and behavior. Toxicol. Ind. Health 14 (1998) 239-260
63. vom Saal F.S., and Hughes C. An extensive new literature concerning low-dose effects of bisphenol A shows the need for a new risk assessment. Environ. Health Perspect. 113 (2005) 926-933
64. Wozniak A.L., Bulayeva N.N., and Watson C.S. Xenoestrogens at picomolar to nanomolar concentrations trigger membrane estrogen receptor-α-mediated Ca++ fluxes and prolactin release in GH3/B6 pituitary tumor cells. Environ. Health Perspect. 113 (2005) 431-439
65. Zoeller R.T., Bansal R., and Parris C. Bisphenol-A, an environmental contaminant that acts as a thyroid hormone receptor antagonist in vitro, increases serum thyroxine, and alters RC3/neurogranin expression in the developing rat brain. Endocrinology 146 (2005) 607-612