-
1
-
-
0032925361
-
Specific inhibitors of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways block inducible nitric oxide synthase and tumor necrosis factor accumulation in murine macrophages stimulated with lipopolysaccharide and interferon-gamma
-
Ajizan SJ, English BK, Meals EA (1999) Specific inhibitors of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways block inducible nitric oxide synthase and tumor necrosis factor accumulation in murine macrophages stimulated with lipopolysaccharide and interferon-gamma. J Infect Dis 179:939–944
-
(1999)
J Infect Dis
, vol.179
, pp. 939-944
-
-
Ajizan, S.J.1
English, B.K.2
Meals, E.A.3
-
2
-
-
0030481770
-
Triterpene alcohols from the flowers of compositae and anti-inflammatory effects
-
COI: 1:CAS:528:DyaK28XnsF2rt7Y%3D, PID: 8987908
-
Akihisa T, Yasukawa K, Oinuma H, Kasahara Y, Yamanouchi S, Takido M, Kumaki K, Tamura T (1996) Triterpene alcohols from the flowers of compositae and anti-inflammatory effects. Phytochemistry 43:1255–1260
-
(1996)
Phytochemistry
, vol.43
, pp. 1255-1260
-
-
Akihisa, T.1
Yasukawa, K.2
Oinuma, H.3
Kasahara, Y.4
Yamanouchi, S.5
Takido, M.6
Kumaki, K.7
Tamura, T.8
-
3
-
-
33846957719
-
Neuronal damage in brain inflammation
-
PID: 17296833
-
Aktas O, Ullrich O, Infante-Duarte C, Nitsch R, Zipp F (2007) Neuronal damage in brain inflammation. Arch Neurol 64:185–189
-
(2007)
Arch Neurol
, vol.64
, pp. 185-189
-
-
Aktas, O.1
Ullrich, O.2
Infante-Duarte, C.3
Nitsch, R.4
Zipp, F.5
-
4
-
-
84919644246
-
Melatonin attenuates D-galactose-induced memory impairment, neuroinflammation and neurodegeneration via RAGE/NF-K B/JNK signaling pathway in aging mouse model
-
COI: 1:CAS:528:DC%2BC2cXitFSitL7E, PID: 25401971
-
Ali T, Badshah H, Kim TH, Kim MO (2015) Melatonin attenuates D-galactose-induced memory impairment, neuroinflammation and neurodegeneration via RAGE/NF-K B/JNK signaling pathway in aging mouse model. J Pineal Res 58:71–85
-
(2015)
J Pineal Res
, vol.58
, pp. 71-85
-
-
Ali, T.1
Badshah, H.2
Kim, T.H.3
Kim, M.O.4
-
5
-
-
84886951607
-
Anthocyanins attenuate body weight gain via modulating neuropeptide Y and GABAB1 receptor in rats’ hypothalamus
-
COI: 1:CAS:528:DC%2BC3sXhtVGktbzN, PID: 23830691
-
Badshah H, Ullah I, Kim SE, Kim TH, Lee HY, Kim MO (2013) Anthocyanins attenuate body weight gain via modulating neuropeptide Y and GABAB1 receptor in rats’ hypothalamus. Neuropeptides 47:347–353
-
(2013)
Neuropeptides
, vol.47
, pp. 347-353
-
-
Badshah, H.1
Ullah, I.2
Kim, S.E.3
Kim, T.H.4
Lee, H.Y.5
Kim, M.O.6
-
6
-
-
84901068755
-
Apomorphine attenuates ethanol-induced neurodegeneration in the adult rat cortex
-
COI: 1:CAS:528:DC%2BC2cXhtF2kt7%2FJ, PID: 24795108
-
Badshah H, Kim TH, Kim MJ, Ahmad A, Ali T, Yoon GH, Naseer MI, Kim MO (2014) Apomorphine attenuates ethanol-induced neurodegeneration in the adult rat cortex. Neurochem Int 74:8–15
-
(2014)
Neurochem Int
, vol.74
, pp. 8-15
-
-
Badshah, H.1
Kim, T.H.2
Kim, M.J.3
Ahmad, A.4
Ali, T.5
Yoon, G.H.6
Naseer, M.I.7
Kim, M.O.8
-
7
-
-
33645953625
-
Suppression of T lymphocyte activity by lupeol isolated from Crataeva religiosa
-
COI: 1:CAS:528:DC%2BD28XkslamsL4%3D, PID: 16557610
-
Bani S, Kaul A, Khan B, Ahmad SF, Suri KA, Gupta BD, Satti NK, Qazi GN (2006) Suppression of T lymphocyte activity by lupeol isolated from Crataeva religiosa. Phytother Res 20:279–287
-
(2006)
Phytother Res
, vol.20
, pp. 279-287
-
-
Bani, S.1
Kaul, A.2
Khan, B.3
Ahmad, S.F.4
Suri, K.A.5
Gupta, B.D.6
Satti, N.K.7
Qazi, G.N.8
-
8
-
-
33749238345
-
Stress activated protein kinases, JNK and p38, as new therapeutic approach for neurodegenerative diseases
-
Bendottil C, Tortarolol M, Borsellol T (2006) Stress activated protein kinases, JNK and p38, as new therapeutic approach for neurodegenerative diseases. Cent Nerv Syst Agents Med Chem 6:109
-
(2006)
Cent Nerv Syst Agents Med Chem
, vol.6
, pp. 109
-
-
Bendottil, C.1
Tortarolol, M.2
Borsellol, T.3
-
9
-
-
70349795301
-
Harnessing immune alterations in neurodegenerative diseases
-
PID: 19840543
-
Bjorkqvist M, Wild EJ, Tabrizi SJ (2009) Harnessing immune alterations in neurodegenerative diseases. Neuron 64:21–24
-
(2009)
Neuron
, vol.64
, pp. 21-24
-
-
Bjorkqvist, M.1
Wild, E.J.2
Tabrizi, S.J.3
-
10
-
-
33845768784
-
Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
-
COI: 1:CAS:528:DC%2BD28XhtlemtL7M, PID: 17180163
-
Block ML, Zecca L, Hong JS (2007) Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat Rev Neurosci 8:57–69
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 57-69
-
-
Block, M.L.1
Zecca, L.2
Hong, J.S.3
-
11
-
-
84860208454
-
Rhinacanthus nasutus extracts prevent glutamate and amyloid-β neurotoxicity in HT-22 mouse hippocampal cells: Possible active compounds include lupeol, stigmasterol, and β-sitosterol
-
COI: 1:CAS:528:DC%2BC38Xmslagu7s%3D, PID: 22606031
-
Brimson JM, Brimson SJ, Brimson CA, Rakkhitawatthana V, Tencomnao T (2012) Rhinacanthus nasutus extracts prevent glutamate and amyloid-β neurotoxicity in HT-22 mouse hippocampal cells: Possible active compounds include lupeol, stigmasterol, and β-sitosterol. Int J Mol Sci 13:5074–5097
-
(2012)
Int J Mol Sci
, vol.13
, pp. 5074-5097
-
-
Brimson, J.M.1
Brimson, S.J.2
Brimson, C.A.3
Rakkhitawatthana, V.4
Tencomnao, T.5
-
12
-
-
77955085839
-
Inflammatory neurodegeneration and mechanisms of microglial killing of neurons
-
COI: 1:CAS:528:DC%2BC3cXmsFSqs7o%3D, PID: 20195798
-
Brown GC, Neher JJ (2010) Inflammatory neurodegeneration and mechanisms of microglial killing of neurons. Mol Neurobiol 41:242–247
-
(2010)
Mol Neurobiol
, vol.41
, pp. 242-247
-
-
Brown, G.C.1
Neher, J.J.2
-
13
-
-
84866440805
-
CYP2E1 sensitizes the liver to LPS- and Tnf α-induced toxicity via elevated oxidative and nitrosative stress and activation of ASK-1 and JNK mitogen-activated kinases
-
Cederbaum AI, Yang L, Wang X, Wu D (2012) CYP2E1 sensitizes the liver to LPS- and Tnf α-induced toxicity via elevated oxidative and nitrosative stress and activation of ASK-1 and JNK mitogen-activated kinases. Int J Hepatol 582790
-
(2012)
Int J Hepatol
-
-
Cederbaum, A.I.1
Yang, L.2
Wang, X.3
Wu, D.4
-
14
-
-
20344397715
-
Endotoxin-induced myocardial dysfunction
-
COI: 1:CAS:528:DC%2BD2MXktlKku7g%3D, PID: 15879312
-
Chagnon F, Metz CN, Bucala R, Lesur O (2005) Endotoxin-induced myocardial dysfunction. Circ Res 96:1095–1102
-
(2005)
Circ Res
, vol.96
, pp. 1095-1102
-
-
Chagnon, F.1
Metz, C.N.2
Bucala, R.3
Lesur, O.4
-
15
-
-
0028717745
-
Aloe vera, hydrocortisone, and sterol influence on wound tensile strength and anti-inflammation
-
COI: 1:STN:280:DyaK2M7ls1ahuw%3D%3D, PID: 7853156
-
Davis RH, DiDonato JJ, Johnson RW, Stewart CB (1994) Aloe vera, hydrocortisone, and sterol influence on wound tensile strength and anti-inflammation. J Am Podiatr Med Assoc 84:614–621
-
(1994)
J Am Podiatr Med Assoc
, vol.84
, pp. 614-621
-
-
Davis, R.H.1
DiDonato, J.J.2
Johnson, R.W.3
Stewart, C.B.4
-
16
-
-
0037069929
-
Chemotherapy: targeting the mitochondrial cell death pathway
-
COI: 1:CAS:528:DC%2BD38XpsFShurc%3D, PID: 12483532
-
Debatin KM, Poncet D, Kroemer G (2002) Chemotherapy: targeting the mitochondrial cell death pathway. Oncogene 21:8786–8803
-
(2002)
Oncogene
, vol.21
, pp. 8786-8803
-
-
Debatin, K.M.1
Poncet, D.2
Kroemer, G.3
-
17
-
-
77956198871
-
Mitochondria and the link between neuroinflammation and neurodegenertion
-
Di Filippo M, Chiasserini D, Tozzi A, Picconi B, Calabresi P (2010) Mitochondria and the link between neuroinflammation and neurodegenertion. J Alzheimers Dis 20:369–379
-
(2010)
J Alzheimers Dis
, vol.20
, pp. 369-379
-
-
Di Filippo, M.1
Chiasserini, D.2
Tozzi, A.3
Picconi, B.4
Calabresi, P.5
-
18
-
-
66349095098
-
The regulation of inflammatory cytokine secretion in macrophage cell line by the chemical constituents of Rhus sylvestris
-
COI: 1:CAS:528:DC%2BD1MXmvFGisb8%3D
-
Ding Y, Nguyen HT, Kim SI, Kim HW, Kim YH (2009) The regulation of inflammatory cytokine secretion in macrophage cell line by the chemical constituents of Rhus sylvestris. Chem Lett 19:3607–3610
-
(2009)
Chem Lett
, vol.19
, pp. 3607-3610
-
-
Ding, Y.1
Nguyen, H.T.2
Kim, S.I.3
Kim, H.W.4
Kim, Y.H.5
-
19
-
-
57349100410
-
Neuroprotective effects of cannabidiol in endotoxin-induced uveitis: critical role of p38 MAPK activation
-
COI: 1:CAS:528:DC%2BD1MXnslKjtw%3D%3D, PID: 19052649
-
El-Remessy AB, Tang Y, Zhy G, Matragoon S, Khalifa Y, Liu EK, Liu JY, Hanson E, Mian S, Fatteh N, Liou GI (2008) Neuroprotective effects of cannabidiol in endotoxin-induced uveitis: critical role of p38 MAPK activation. Mol Vis 14:2190–2203
-
(2008)
Mol Vis
, vol.14
, pp. 2190-2203
-
-
El-Remessy, A.B.1
Tang, Y.2
Zhy, G.3
Matragoon, S.4
Khalifa, Y.5
Liu, E.K.6
Liu, J.Y.7
Hanson, E.8
Mian, S.9
Fatteh, N.10
Liou, G.I.11
-
20
-
-
47749126515
-
Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression
-
COI: 1:CAS:528:DC%2BD1cXptVCit7w%3D, PID: 18599350
-
Gao HM, Hong JS (2008) Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression. Trends Immunol 29:357–365
-
(2008)
Trends Immunol
, vol.29
, pp. 357-365
-
-
Gao, H.M.1
Hong, J.S.2
-
21
-
-
0035399785
-
Microglia in neurodegeneration: molecular aspects
-
COI: 1:CAS:528:DC%2BD3MXltVagsro%3D, PID: 11526957
-
Gebicke-Haerter PJ (2001) Microglia in neurodegeneration: molecular aspects. Microsc Res Tech 54:47–58
-
(2001)
Microsc Res Tech
, vol.54
, pp. 47-58
-
-
Gebicke-Haerter, P.J.1
-
22
-
-
84862158991
-
Evaluation of antidiabetic and antioxidant potential of lupeol in experimental hyperglycemia
-
COI: 1:CAS:528:DC%2BC38XnslejsLY%3D, PID: 22043924
-
Gupta R, Sharma AK, Sharma MC, Dobhal MP, Gupta RS (2012) Evaluation of antidiabetic and antioxidant potential of lupeol in experimental hyperglycemia. Nat Prod Res 26:1125–1129
-
(2012)
Nat Prod Res
, vol.26
, pp. 1125-1129
-
-
Gupta, R.1
Sharma, A.K.2
Sharma, M.C.3
Dobhal, M.P.4
Gupta, R.S.5
-
23
-
-
0034931503
-
C-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis
-
COI: 1:CAS:528:DC%2BD3MXkvVars7s%3D
-
Han Z, Boyle DL, Chang L, Bennett B, Karin M, Yang L, Manning AM, Firestein GS (2001) C-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis. Clin Investig 108:73–81
-
(2001)
Clin Investig
, vol.108
, pp. 73-81
-
-
Han, Z.1
Boyle, D.L.2
Chang, L.3
Bennett, B.4
Karin, M.5
Yang, L.6
Manning, A.M.7
Firestein, G.S.8
-
24
-
-
79951607525
-
Inights into sepsis therapeutic design based on the apoptotic death pathway
-
COI: 1:CAS:528:DC%2BC3MXisFOmsg%3D%3D, PID: 21081836
-
Hattori Y, Takano K, Teramae H, Yamamoto S, Yokoo H, Matsuda N (2010) Inights into sepsis therapeutic design based on the apoptotic death pathway. J Pharmacol Sci 114:354–365
-
(2010)
J Pharmacol Sci
, vol.114
, pp. 354-365
-
-
Hattori, Y.1
Takano, K.2
Teramae, H.3
Yamamoto, S.4
Yokoo, H.5
Matsuda, N.6
-
25
-
-
33745873475
-
Astrocyte control of synaptic transmission and neurovascular coupling
-
COI: 1:CAS:528:DC%2BD28XnsFGgtbY%3D, PID: 16816144
-
Haydon PG, Carmignoto G (2006) Astrocyte control of synaptic transmission and neurovascular coupling. Physiol Rev 86:1009–1031
-
(2006)
Physiol Rev
, vol.86
, pp. 1009-1031
-
-
Haydon, P.G.1
Carmignoto, G.2
-
26
-
-
79953768579
-
Growth inhibition and apoptosis induced by lupeol, a dietary triterpene, in human hepatocellular carcinoma cells
-
COI: 1:CAS:528:DC%2BC38XpslarsA%3D%3D, PID: 21467639
-
He Y, Liu F, Zhang L, Wu Y, Hu B, Zhang Y, Li Y, Liu H (2011) Growth inhibition and apoptosis induced by lupeol, a dietary triterpene, in human hepatocellular carcinoma cells. Biol Pharm Bull 34:517–522
-
(2011)
Biol Pharm Bull
, vol.34
, pp. 517-522
-
-
He, Y.1
Liu, F.2
Zhang, L.3
Wu, Y.4
Hu, B.5
Zhang, Y.6
Li, Y.7
Liu, H.8
-
27
-
-
33847613885
-
Inflammatory processes in Alzheimer’s disease
-
COI: 1:CAS:528:DC%2BD2sXislejtLo%3D, PID: 17222916
-
Heneka MT, O’Banion MK (2007) Inflammatory processes in Alzheimer’s disease. J Neuroimmunol 184:69–91
-
(2007)
J Neuroimmunol
, vol.184
, pp. 69-91
-
-
Heneka, M.T.1
O’Banion, M.K.2
-
28
-
-
62549133546
-
Neuroinflammation in Parkinson, s disease: a target for neuroprotection?
-
COI: 1:CAS:528:DC%2BD1MXks1Sis70%3D, PID: 19296921
-
Hirsch EC, Hunot S (2009) Neuroinflammation in Parkinson, s disease: a target for neuroprotection? Lancet Neurol 8:382–397
-
(2009)
Lancet Neurol
, vol.8
, pp. 382-397
-
-
Hirsch, E.C.1
Hunot, S.2
-
29
-
-
0032770246
-
Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction
-
COI: 1:STN:280:DyaK1MznsVCrsg%3D%3D, PID: 10446814
-
Hotchkiss RS, Swanson PE, Freeman BD, Tinsley KW, Cobb JP, Matuschak GM, Buchman TG, Karl IE (1999) Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction. Crit Care Med 27:1230–1251
-
(1999)
Crit Care Med
, vol.27
, pp. 1230-1251
-
-
Hotchkiss, R.S.1
Swanson, P.E.2
Freeman, B.D.3
Tinsley, K.W.4
Cobb, J.P.5
Matuschak, G.M.6
Buchman, T.G.7
Karl, I.E.8
-
30
-
-
84903624841
-
L-ascorbate attenuates the endotoxin-induced production of inflammatory mediators by inhibiting MAPK activation and NFκB translocation in cortical neurons/glia cocultures
-
PID: 24983461
-
Huang YN, Lai CC, Lin JJ, Wang JY (2014) L-ascorbate attenuates the endotoxin-induced production of inflammatory mediators by inhibiting MAPK activation and NFκB translocation in cortical neurons/glia cocultures. PLoS ONE 9, e97276
-
(2014)
PLoS ONE
, vol.9
-
-
Huang, Y.N.1
Lai, C.C.2
Lin, J.J.3
Wang, J.Y.4
-
31
-
-
79952318766
-
Endotoxin-activated microglia injure brain derived endothelial cells via NF-κB. JAK-STAT and JNK stress kinase pathways
-
COI: 1:CAS:528:DC%2BC3MXjvVClurY%3D
-
Kacimi R, Giffard RG, Yenari MA (2011) Endotoxin-activated microglia injure brain derived endothelial cells via NF-κB. JAK-STAT and JNK stress kinase pathways. J Inflamm (Lond) 8:7
-
(2011)
J Inflamm (Lond)
, vol.8
, pp. 7
-
-
Kacimi, R.1
Giffard, R.G.2
Yenari, M.A.3
-
32
-
-
77951260924
-
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
-
COI: 1:CAS:528:DC%2BC3cXkvFSjsrc%3D, PID: 20404851
-
Kawai T, Akira S (2010) The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat Immunol 11:373–384
-
(2010)
Nat Immunol
, vol.11
, pp. 373-384
-
-
Kawai, T.1
Akira, S.2
-
33
-
-
84859704746
-
Lupeol prevents acetaminophen-induced in vivo hepatotoxicity by altering the Bax/Bcl-2 and oxidative stress-mediated mitochondrial signaling cascade
-
COI: 1:CAS:528:DC%2BC38XksleitL4%3D, PID: 22326499
-
Kumari A, Kakkar P (2012a) Lupeol prevents acetaminophen-induced in vivo hepatotoxicity by altering the Bax/Bcl-2 and oxidative stress-mediated mitochondrial signaling cascade. Life Sci 90:561–570
-
(2012)
Life Sci
, vol.90
, pp. 561-570
-
-
Kumari, A.1
Kakkar, P.2
-
34
-
-
84859874739
-
Lupeol protects against acetaminophen-induced oxidative stress and cell death in rat primary hepatocytes
-
COI: 1:CAS:528:DC%2BC38XmtVCjtrk%3D, PID: 22406326
-
Kumari A, Kakkar P (2012b) Lupeol protects against acetaminophen-induced oxidative stress and cell death in rat primary hepatocytes. Food Chem Toxicol 50:1781–1789
-
(2012)
Food Chem Toxicol
, vol.50
, pp. 1781-1789
-
-
Kumari, A.1
Kakkar, P.2
-
35
-
-
84860165740
-
Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update
-
COI: 1:CAS:528:DC%2BC38XptF2kur8%3D, PID: 22535895
-
Kyriakis JM, Ayruch J (2012) Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update. Physiol Rev 92:689–737
-
(2012)
Physiol Rev
, vol.92
, pp. 689-737
-
-
Kyriakis, J.M.1
Ayruch, J.2
-
36
-
-
0035066383
-
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
-
Kyriasis JM, Avruch J (2001) Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 81:807–869
-
(2001)
Physiol Rev
, vol.81
, pp. 807-869
-
-
Kyriasis, J.M.1
Avruch, J.2
-
37
-
-
77957028140
-
Microglial activation and chronic neurodegeneration
-
COI: 1:CAS:528:DC%2BC3cXht1SqsLnO, PID: 20880500
-
Lull ME, Block ML (2010) Microglial activation and chronic neurodegeneration. Neurotherapeutics 7:354–365
-
(2010)
Neurotherapeutics
, vol.7
, pp. 354-365
-
-
Lull, M.E.1
Block, M.L.2
-
38
-
-
33751237994
-
Mechanism of disease: astrocytes in neurodegenerative disease
-
COI: 1:CAS:528:DC%2BD28XhtlajurzP, PID: 17117171
-
Maragakis NJ, Rothstein JD (2006) Mechanism of disease: astrocytes in neurodegenerative disease. Nat Clin Pract Neurol 2:679–689
-
(2006)
Nat Clin Pract Neurol
, vol.2
, pp. 679-689
-
-
Maragakis, N.J.1
Rothstein, J.D.2
-
40
-
-
35348886061
-
A novel P38MAPK inhibitor suppresses brain proinflammatory cytokine
-
PID: 17784957
-
Munoz L, Ranaivo HR, Rov SR, Hu W, Craft JM, McNamara LK, Chico LW, Van Eldik LJ, Watterso DM (2007) A novel P38MAPK inhibitor suppresses brain proinflammatory cytokine. J Neuroinflammation 4:21
-
(2007)
J Neuroinflammation
, vol.4
, pp. 21
-
-
Munoz, L.1
Ranaivo, H.R.2
Rov, S.R.3
Hu, W.4
Craft, J.M.5
McNamara, L.K.6
Chico, L.W.7
Van Eldik, L.J.8
Watterso, D.M.9
-
41
-
-
0036604133
-
Lipopolysaccharide-induced apoptosis of endothelial cells and its inhibition by vascular endothelial growth factor
-
COI: 1:CAS:528:DC%2BD38XktFCrtL0%3D, PID: 12023390
-
Munshi N, Fernandis AZ, Cherla RP, Park IW, Ganju RK (2002) Lipopolysaccharide-induced apoptosis of endothelial cells and its inhibition by vascular endothelial growth factor. J Immunol 168:5860–5866
-
(2002)
J Immunol
, vol.168
, pp. 5860-5866
-
-
Munshi, N.1
Fernandis, A.Z.2
Cherla, R.P.3
Park, I.W.4
Ganju, R.K.5
-
42
-
-
0242299717
-
Protien kinase C alpha requirement in the activation of p38 mitogen-activated protein kinase, which is linked to the induction of tumor necrosis factor alpha in lipopolysaccharide-stimulated microglia
-
COI: 1:CAS:528:DC%2BD3sXos1Onsb4%3D, PID: 14602083
-
Nakajima K, Tohyama Y, Kohsaka S, Kurihara T (2004) Protien kinase C alpha requirement in the activation of p38 mitogen-activated protein kinase, which is linked to the induction of tumor necrosis factor alpha in lipopolysaccharide-stimulated microglia. Neurochem Int 44:205–214
-
(2004)
Neurochem Int
, vol.44
, pp. 205-214
-
-
Nakajima, K.1
Tohyama, Y.2
Kohsaka, S.3
Kurihara, T.4
-
43
-
-
19744380563
-
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
-
COI: 1:CAS:528:DC%2BD2MXks1Ciuro%3D, PID: 15831717
-
Nimmerjahn A, Kirchhoff F, Helmchen F (2005) Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 308:1314–1318
-
(2005)
Science
, vol.308
, pp. 1314-1318
-
-
Nimmerjahn, A.1
Kirchhoff, F.2
Helmchen, F.3
-
44
-
-
4744370253
-
Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4
-
COI: 1:CAS:528:DC%2BD2cXot1Kiu7c%3D, PID: 15379975
-
Palsson-McDermott EM, O’Neill LA (2004) Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4. Immunology 113:153–162
-
(2004)
Immunology
, vol.113
, pp. 153-162
-
-
Palsson-McDermott, E.M.1
O’Neill, L.A.2
-
45
-
-
67649934729
-
Synthesis of novel triterpenoid (lupeol) derivatives and their in vivo antihyperglycemic and antidyslipidemic activity
-
Papi Reddy K, Singh AB, Puri A, Srivastava AK, Narender T (2009) Synthesis of novel triterpenoid (lupeol) derivatives and their in vivo antihyperglycemic and antidyslipidemic activity. Bioorg Med Chem Lett 4463–6
-
(2009)
Bioorg Med Chem Lett
, pp. 4463-4466
-
-
Papi Reddy, K.1
Singh, A.B.2
Puri, A.3
Srivastava, A.K.4
Narender, T.5
-
46
-
-
84870899355
-
GM-CSF increase LPS-induced production of proinflammatory mediators via upregulation of TLR4 and CD14 in murine microglia
-
COI: 1:CAS:528:DC%2BC3sXjtVKhtbs%3D, PID: 23234315
-
Parajuli B, Sonobe Y, Kawanokuchi J, Doi Y, Noda M, Takeuchi H, Mizuno T, Suzumura A (2012) GM-CSF increase LPS-induced production of proinflammatory mediators via upregulation of TLR4 and CD14 in murine microglia. J Neuroinflammation 9:268
-
(2012)
J Neuroinflammation
, vol.9
, pp. 268
-
-
Parajuli, B.1
Sonobe, Y.2
Kawanokuchi, J.3
Doi, Y.4
Noda, M.5
Takeuchi, H.6
Mizuno, T.7
Suzumura, A.8
-
47
-
-
0037860975
-
JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis
-
Putcha GV, Le S, Frank S, Besirli CG, Clark K, Chu B, Alix S, Youle RJ, LaMarche A, Maroney AC, Johnson EM Jr (2003) JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis. Neuron 19:899–914
-
(2003)
Neuron
, vol.19
, pp. 899-914
-
-
Putcha, G.V.1
Le, S.2
Frank, S.3
Besirli, C.G.4
Clark, K.5
Chu, B.6
Alix, S.7
Youle, R.J.8
LaMarche, A.9
Maroney, A.C.10
Johnson, E.M.11
-
48
-
-
0036345942
-
Irritant potential of triterpenoids from Ficus carica leaves
-
COI: 1:CAS:528:DC%2BD38XlvF2qsr8%3D, PID: 12165340
-
Saeed MA, Sabir AW (2002) Irritant potential of triterpenoids from Ficus carica leaves. Fitoterapia 73:417–420
-
(2002)
Fitoterapia
, vol.73
, pp. 417-420
-
-
Saeed, M.A.1
Sabir, A.W.2
-
49
-
-
0034714392
-
Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration
-
COI: 1:CAS:528:DC%2BD3cXlvV2mtb4%3D, PID: 10960596
-
Schmued LC, Hopkins KJ (2000) Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration. Brain Res 874:123–130
-
(2000)
Brain Res
, vol.874
, pp. 123-130
-
-
Schmued, L.C.1
Hopkins, K.J.2
-
50
-
-
84934271980
-
Novel osmotin attenuates glutamate-induced synaptic dysfunction and neurodegeneration via the JNK/PI3K/Akt pathway in postnatal rat brain
-
Shah SA, Lee HY, Bressan RA, Yun DJ, Kim MO (2014) Novel osmotin attenuates glutamate-induced synaptic dysfunction and neurodegeneration via the JNK/PI3K/Akt pathway in postnatal rat brain. Cell Death Dis 5:1026
-
(2014)
Cell Death Dis
, vol.5
, pp. 1026
-
-
Shah, S.A.1
Lee, H.Y.2
Bressan, R.A.3
Yun, D.J.4
Kim, M.O.5
-
51
-
-
0036098552
-
AP-1 as a regulator of cell life and death
-
Shaulian E, Karin M (2002) AP-1 as a regulator of cell life and death. Nat Cell Biol 4:131–136
-
(2002)
Nat Cell Biol
, vol.4
, pp. 131-136
-
-
Shaulian, E.1
Karin, M.2
-
52
-
-
79952685411
-
Beneficial health effects of lupeol triterpene: a review of preclinical studies
-
COI: 1:CAS:528:DC%2BC3MXhsFyktro%3D, PID: 21118697
-
Siddique HR, Saleem M (2011) Beneficial health effects of lupeol triterpene: a review of preclinical studies. Life Sci 88:285–293
-
(2011)
Life Sci
, vol.88
, pp. 285-293
-
-
Siddique, H.R.1
Saleem, M.2
-
53
-
-
80051691651
-
Lupeol, a novel androgen receptor inhibitor: implications in prostate cancer therapy
-
COI: 1:CAS:528:DC%2BC3MXhtVajs7nE
-
Siddique HR, Mishra SK, Karnes RJ, Saleem M (2011) Lupeol, a novel androgen receptor inhibitor: implications in prostate cancer therapy. Cancer Res 17:5379–5391
-
(2011)
Cancer Res
, vol.17
, pp. 5379-5391
-
-
Siddique, H.R.1
Mishra, S.K.2
Karnes, R.J.3
Saleem, M.4
-
54
-
-
37049020205
-
The brain as a target for inflammatory processes and neuroprotective strategies
-
COI: 1:CAS:528:DC%2BD1cXhtVOks7Y%3D, PID: 18077562
-
Skaper SD (2007) The brain as a target for inflammatory processes and neuroprotective strategies. Ann N Y Acad Sci 1122:23–34
-
(2007)
Ann N Y Acad Sci
, vol.1122
, pp. 23-34
-
-
Skaper, S.D.1
-
55
-
-
0344945470
-
Activation and cellular localization of the p38 and JNK MAPK pathways in rat crescentic glomerulonephritis
-
COI: 1:CAS:528:DC%2BD3sXpvFOqsLc%3D, PID: 14633134
-
Stambe C, Atkins RC, Hill PA, Nikolic-Paterson DJ (2003) Activation and cellular localization of the p38 and JNK MAPK pathways in rat crescentic glomerulonephritis. Kidney Int 64:2121–2132
-
(2003)
Kidney Int
, vol.64
, pp. 2121-2132
-
-
Stambe, C.1
Atkins, R.C.2
Hill, P.A.3
Nikolic-Paterson, D.J.4
-
57
-
-
0034607702
-
Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway
-
COI: 1:CAS:528:DC%2BD3cXjtFGisLg%3D, PID: 10797012
-
Tournier C, Hess P, Yang DD, Xu J, Turner TK, Nimnual A, Bar-Sagi D, Jones SN, Flavell RA, Davis RJ (2000) Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Science 288:870–874
-
(2000)
Science
, vol.288
, pp. 870-874
-
-
Tournier, C.1
Hess, P.2
Yang, D.D.3
Xu, J.4
Turner, T.K.5
Nimnual, A.6
Bar-Sagi, D.7
Jones, S.N.8
Flavell, R.A.9
Davis, R.J.10
-
58
-
-
84864809901
-
JNK signaling is the shared pathway linking neuroinflammation, blood–brain barrier disruption, and oligodendroglial apoptosis in the white matter injury of the immature brain
-
COI: 1:CAS:528:DC%2BC38Xhsl2jt77L, PID: 22805152
-
Wang LW, Tu YF, Huang CC, Ho CJ (2012) JNK signaling is the shared pathway linking neuroinflammation, blood–brain barrier disruption, and oligodendroglial apoptosis in the white matter injury of the immature brain. J Neuroinflammation 9:175
-
(2012)
J Neuroinflammation
, vol.9
, pp. 175
-
-
Wang, L.W.1
Tu, Y.F.2
Huang, C.C.3
Ho, C.J.4
-
59
-
-
83655211771
-
Microglial p38α MAPK is critical for LPS-induced neuron degeneration, through a mechanism involving TNFα
-
COI: 1:CAS:528:DC%2BC38XkvVOqurY%3D, PID: 22185458
-
Xing B, Bachstetter AD, Van Eldik LJ (2011) Microglial p38α MAPK is critical for LPS-induced neuron degeneration, through a mechanism involving TNFα. Mol Neurodegener 6:84
-
(2011)
Mol Neurodegener
, vol.6
, pp. 84
-
-
Xing, B.1
Bachstetter, A.D.2
Van Eldik, L.J.3
-
60
-
-
79953008825
-
p38 MAP kinase inhibitors as potential therapeutic drugs for neural diseases
-
COI: 1:CAS:528:DC%2BC3MXktVOrs74%3D, PID: 20812905
-
Yasuda S, Sugiura H, Tanaka H, Takigami S, Yamagata K (2011) p38 MAP kinase inhibitors as potential therapeutic drugs for neural diseases. Cent Nerv Syst Agents Med Chem 11:45–59
-
(2011)
Cent Nerv Syst Agents Med Chem
, vol.11
, pp. 45-59
-
-
Yasuda, S.1
Sugiura, H.2
Tanaka, H.3
Takigami, S.4
Yamagata, K.5
-
61
-
-
19644367000
-
Activation and signaling of p38 MAP kinase pathway
-
COI: 1:CAS:528:DC%2BD2MXkslGisb4%3D, PID: 15686620
-
Zarubin T, Han J (2005) Activation and signaling of p38 MAP kinase pathway. Cell Res 15:11–18
-
(2005)
Cell Res
, vol.15
, pp. 11-18
-
-
Zarubin, T.1
Han, J.2
|