Growth inhibition and apoptosis induced by Lupeol, a dietary triterpene, in human hepatocellular carcinoma cells

Biological and Pharmaceutical Bulletin

Volumn 34, Issue 4, 2011, Pages 517-522

  He, Yan ^a   Liu, Fen ^a   Zhang, Lurong ^a,b   Wu, Yan ^a   Hu, Bo ^a   Zhang, Yinsheng ^a   Li, Yunsen ^a   Liu, Haiyan ^a  

^a SOOCHOW UNIVERSITY   (China)

^b Suzhou Hospital of Traditional Chinese Medicine   (China)

Author keywords

Apoptosis; Hepatocellular carcinoma; Lupeol; Tumor necrosis factor related apoptosis inducing ligand

Indexed keywords

CASPASE 3; LUPEOL; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; RECOMBINANT TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CELL CYCLE S PHASE; CELL STRAIN HEPG2; CELL STRAIN SMMC7721; CELL VIABILITY; CELLULAR DISTRIBUTION; CHEMOSENSITIZATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG SENSITIVITY; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; NUDE MOUSE; PROTEIN CLEAVAGE; PROTEIN EXPRESSION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CASPASE 3; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CHEMOTHERAPY, ADJUVANT; DOSE-RESPONSE RELATIONSHIP, DRUG; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MICE; MICE, NUDE; PENTACYCLIC TRITERPENES; PHYTOTHERAPY; PLANT EXTRACTS; POLY(ADP-RIBOSE) POLYMERASES; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 79953768579     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.34.517     Document Type: Article

References (35)

1. El-Serag H. B., Rudolph K. L., Gastroenterology, 132, 2557-2576 (2007).
2. Parkin D. M., Bray F., Ferlay J., Pisani P., CA Cancer J. Clin., 55, 74-108 (2005).
3. Padma S., Martinie J. B., Iannitti D. A., J. Surg. Oncol., 100, 619-634 (2009).
4. Poon D., Anderson B. O., Chen L. T., Tanaka K., Lau W. Y., Van Cutsem E., Singh H., Chow W. C., Ooi L. L., Chow P., Khin M. W., Koo W. H., Lancet Oncol., 10, 1111-1118 (2009).
5. Rampone B., Schiavone B., Confuorto G., Curr. Oncol. Rep., 12, 186-192 (2010).
6. Bruix J., Sherman M., Hepatology, 42, 1208-1236 (2005).
7. Llovet J. M., Bruix J., Hepatology, 37, 429-442 (2003).
8. Lachenmayer A., Alsinet C., Chang C. Y., Dig. Liver Dis., 42 (Suppl. 3), S264-S272 (2010).
9. Lima L. M., Perazzo F. F., Tavares Carvalho J. C., Bastos J. K., J. Pharm. Pharmacol., 59, 1151-1158 (2007).
10. Prasad S., Kalra N., Singh M., Shukla Y., Asian J. Androl., 10, 313-318 (2008).
11. Geetha T., Varalakshmi P., J. Ethnopharmacol., 76, 77-80 (2001).
12. Chaturvedi P. K., Bhui K., Shukla Y., Cancer Lett., 263, 1-13 (2008).
13. Lee T. K., Poon R. T., Wo J. Y., Ma S., Guan X. Y., Myers J. N., Altevogt P., Yuen A. P., Cancer Res., 67, 8800-8809 (2007).
14. Saleem M., Kweon M. H., Yun J. M., Adhami V. M., Khan N., Syed D. N., Mukhtar H., Cancer Res., 65, 11203-11213 (2005).
15. Saleem M., Kaur S., Kweon M. H., Adhami V. M., Afaq F., Mukhtar H., Carcinogenesis, 26, 1956-1964 (2005).
16. Hata K., Ishikawa K., Hori K., Konishi T., Biol. Pharm. Bull., 23, 962-967 (2000).
17. Saleem M., Maddodi N., Abu Zaid M., Khan N., bin Hafeez B., Asim M., Suh Y., Yun J. M., Setaluri V., Mukhtar H., Clin. Cancer Res., 14, 2119-2127 (2008).
18. Aratanechemuge Y., Hibasami H., Sanpin K., Katsuzaki H., Imai K., Komiya T., Oncol. Rep., 11, 289-292 (2004).
19. Zhang L., Zhang Y., Zhang L., Yang X., Lv Z., Cancer Investigation, 27, 163-170 (2009).
20. Geetha T., Varalakshmi P., Fitoterapia, 69, 13-19 (1998).
21. Kruyt F. A., Cancer Lett., 263, 14-25 (2008).
22. Ashkenazi A., Pai R. C., Fong S., Leung S., Lawrence D. A., Marsters S. A., Blackie C., Chang L., McMurtrey A. E., Hebert A., DeForge L., Koumenis I. L., Lewis D., Harris L., Bussiere J., Koeppen H., Shahrokh Z., Schwall R. H., J. Clin. Invest., 104, 155-162 (1999).
23. Walczak H., Miller R. E., Ariail K., Gliniak B., Griffith T. S., Kubin M., Chin W., Jones J., Woodward A., Le T., Smith C., Smolak P., Goodwin R. G., Rauch C. T., Schuh J. C., Lynch D. H., Nat. Med., 5, 157-163 (1999).
24. Murtaza I., Saleem M., Adhami V. M., Hafeez B. B., Mukhtar H., Cancer Res., 69, 1156-1165 (2009).
25. Bodmer J. L., Holler N., Reynard S., Vinciguerra P., Schneider P., Juo P., Blenis J., Tschopp J., Nat. Cell Biol., 2, 241-243 (2000).
26. Guicciardi M. E., Bronk S. F., Werneburg N. W., Gores G. J., Am. J. Physiol. Gastrointest. Liver Physiol., 292, G1337-G1346 (2007).
27. Ganten T. M., Koschny R., Haas T. L., Sykora J., Li-Weber M., Herzer K., Walczak H., Hepatology, 42, 588-597 (2005).
28. Guo B. C., Xu Y. H., Acta Pharmacol. Sin., 22, 831-836 (2001).
29. Armeanu S., Lauer U. M., Smirnow I., Schenk M., Weiss T. S., Gregor M., Bitzer M., Cancer Res., 63, 2369-2372 (2003).
30. Nigam N., Prasad S., George J., Shukla Y., Biochem. Biophys. Res. Commun., 381, 253-258 (2009).
31. Ganten T. M., Haas T. L., Sykora J., Stahl H., Sprick M. R., Fas S. C., Krueger A., Weigand M. A., Grosse-Wilde A., Stremmel W., Krammer P. H., Walczak H., Cell Death Differ., 11 (Suppl. 1), S86-S96 (2004).
32. Okano H., Shiraki K., Inoue H., Kawakita T., Yamanaka T., Deguchi M., Sugimoto K., Sakai T., Ohmori S., Fujikawa K., Murata K., Nakano T., Lab. Invest., 83, 1033-1043 (2003).
33. Fabregat I., World J. Gastroenterol., 15, 513-520 (2009).
34. Chen K. F., Yeh P. Y., Hsu C., Hsu C. H., Lu Y. S., Hsieh H. P., Chen P. J., Cheng A. L., J. Biol. Chem., 284, 11121-11133 (2009).
35. Moon D. O., Kim M. O., Choi Y. H., Kim G. Y., Mol. Cancer Ther., 9, 1583-1595 (2010).