메뉴 건너뛰기




Volumn 28, Issue 6, 2015, Pages 743-757

A MYC-Driven Change in Mitochondrial Dynamics Limits YAP/TAZ Function in Mammary Epithelial Cells and Breast Cancer

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MYC PROTEIN; PHOSPHOLIPASE; PLD6 ENZYME; PROTEIN TAZ; PROTEIN YAZ; UNCLASSIFIED DRUG; MYC PROTEIN, HUMAN; PHOSPHOLIPASE D; PHOSPHOPROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TAZ PROTEIN, HUMAN; TRANSCRIPTION FACTOR; YAP1 (YES-ASSOCIATED) PROTEIN, HUMAN;

EID: 84957108114     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccell.2015.10.013     Document Type: Article
Times cited : (118)

References (49)
  • 1
    • 84857570226 scopus 로고    scopus 로고
    • Epithelial stem cells, wound healing and cancer
    • Arwert E.N., Hoste E., Watt F.M. Epithelial stem cells, wound healing and cancer. Nat. Rev. Cancer 2012, 12:170-180.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 170-180
    • Arwert, E.N.1    Hoste, E.2    Watt, F.M.3
  • 2
    • 42649112047 scopus 로고    scopus 로고
    • An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
    • Ben-Porath I., Thomson M.W., Carey V.J., Ge R., Bell G.W., Regev A., Weinberg R.A. An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat. Genet. 2008, 40:499-507.
    • (2008) Nat. Genet. , vol.40 , pp. 499-507
    • Ben-Porath, I.1    Thomson, M.W.2    Carey, V.J.3    Ge, R.4    Bell, G.W.5    Regev, A.6    Weinberg, R.A.7
  • 3
    • 77953658618 scopus 로고    scopus 로고
    • Dose and context dependent effects of Myc on epidermal stem cell proliferation and differentiation
    • Berta M.A., Baker C.M., Cottle D.L., Watt F.M. Dose and context dependent effects of Myc on epidermal stem cell proliferation and differentiation. EMBO Mol. Med. 2010, 2:16-25.
    • (2010) EMBO Mol. Med. , vol.2 , pp. 16-25
    • Berta, M.A.1    Baker, C.M.2    Cottle, D.L.3    Watt, F.M.4
  • 5
    • 16844364151 scopus 로고    scopus 로고
    • LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism
    • Cartwright P., McLean C., Sheppard A., Rivett D., Jones K., Dalton S. LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism. Development 2005, 132:885-896.
    • (2005) Development , vol.132 , pp. 885-896
    • Cartwright, P.1    McLean, C.2    Sheppard, A.3    Rivett, D.4    Jones, K.5    Dalton, S.6
  • 7
    • 84896824055 scopus 로고    scopus 로고
    • A temporal requirement for Hippo signaling in mammary gland differentiation, growth, and tumorigenesis
    • Chen Q., Zhang N., Gray R.S., Li H., Ewald A.J., Zahnow C.A., Pan D. A temporal requirement for Hippo signaling in mammary gland differentiation, growth, and tumorigenesis. Genes Dev. 2014, 28:432-437.
    • (2014) Genes Dev. , vol.28 , pp. 432-437
    • Chen, Q.1    Zhang, N.2    Gray, R.S.3    Li, H.4    Ewald, A.J.5    Zahnow, C.A.6    Pan, D.7
  • 10
    • 84881056831 scopus 로고    scopus 로고
    • MYC, metabolism, cell growth, and tumorigenesis
    • Dang C.V. MYC, metabolism, cell growth, and tumorigenesis. Cold Spring Harb. Perspect. Med. 2013, 3:3.
    • (2013) Cold Spring Harb. Perspect. Med. , vol.3 , pp. 3
    • Dang, C.V.1
  • 12
    • 84902682890 scopus 로고    scopus 로고
    • Posttranscriptional regulation of c-Myc expression in adult murine HSCs during homeostasis and interferon-α-induced stress response
    • Ehninger A., Boch T., Uckelmann H., Essers M.A., Müdder K., Sleckman B.P., Trumpp A. Posttranscriptional regulation of c-Myc expression in adult murine HSCs during homeostasis and interferon-α-induced stress response. Blood 2014, 123:3909-3913.
    • (2014) Blood , vol.123 , pp. 3909-3913
    • Ehninger, A.1    Boch, T.2    Uckelmann, H.3    Essers, M.A.4    Müdder, K.5    Sleckman, B.P.6    Trumpp, A.7
  • 14
    • 65849401051 scopus 로고    scopus 로고
    • The tortoise and the hair: slow-cycling cells in the stem cell race
    • Fuchs E. The tortoise and the hair: slow-cycling cells in the stem cell race. Cell 2009, 137:811-819.
    • (2009) Cell , vol.137 , pp. 811-819
    • Fuchs, E.1
  • 16
    • 79952509006 scopus 로고    scopus 로고
    • PiRNA-associated germline nuage formation and spermatogenesis require MitoPLD profusogenic mitochondrial-surface lipid signaling
    • Huang H., Gao Q., Peng X., Choi S.Y., Sarma K., Ren H., Morris A.J., Frohman M.A. piRNA-associated germline nuage formation and spermatogenesis require MitoPLD profusogenic mitochondrial-surface lipid signaling. Dev. Cell 2011, 20:376-387.
    • (2011) Dev. Cell , vol.20 , pp. 376-387
    • Huang, H.1    Gao, Q.2    Peng, X.3    Choi, S.Y.4    Sarma, K.5    Ren, H.6    Morris, A.J.7    Frohman, M.A.8
  • 18
    • 84875906572 scopus 로고    scopus 로고
    • Mitochondrial dynamics in the regulation of nutrient utilization and energy expenditure
    • Liesa M., Shirihai O.S. Mitochondrial dynamics in the regulation of nutrient utilization and energy expenditure. Cell Metab. 2013, 17:491-506.
    • (2013) Cell Metab. , vol.17 , pp. 491-506
    • Liesa, M.1    Shirihai, O.S.2
  • 19
    • 73149086829 scopus 로고    scopus 로고
    • P21CIP1 attenuates Ras- and c-Myc-dependent breast tumor epithelial mesenchymal transition and cancer stem cell-like gene expression in vivo
    • Liu M., Casimiro M.C., Wang C., Shirley L.A., Jiao X., Katiyar S., Ju X., Li Z., Yu Z., Zhou J., et al. p21CIP1 attenuates Ras- and c-Myc-dependent breast tumor epithelial mesenchymal transition and cancer stem cell-like gene expression in vivo. Proc. Natl. Acad. Sci. U S A 2009, 106:19035-19039.
    • (2009) Proc. Natl. Acad. Sci. U S A , vol.106 , pp. 19035-19039
    • Liu, M.1    Casimiro, M.C.2    Wang, C.3    Shirley, L.A.4    Jiao, X.5    Katiyar, S.6    Ju, X.7    Li, Z.8    Yu, Z.9    Zhou, J.10
  • 20
    • 84861592850 scopus 로고    scopus 로고
    • MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrin subunits
    • Liu H., Radisky D.C., Yang D., Xu R., Radisky E.S., Bissell M.J., Bishop J.M. MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrin subunits. Nat. Cell Biol. 2012, 14:567-574.
    • (2012) Nat. Cell Biol. , vol.14 , pp. 567-574
    • Liu, H.1    Radisky, D.C.2    Yang, D.3    Xu, R.4    Radisky, E.S.5    Bissell, M.J.6    Bishop, J.M.7
  • 22
    • 84879753699 scopus 로고    scopus 로고
    • Temporal reduction of LATS kinases in the early preimplantation embryo prevents ICM lineage differentiation
    • Lorthongpanich C., Messerschmidt D.M., Chan S.W., Hong W., Knowles B.B., Solter D. Temporal reduction of LATS kinases in the early preimplantation embryo prevents ICM lineage differentiation. Genes Dev. 2013, 27:1441-1446.
    • (2013) Genes Dev. , vol.27 , pp. 1441-1446
    • Lorthongpanich, C.1    Messerschmidt, D.M.2    Chan, S.W.3    Hong, W.4    Knowles, B.B.5    Solter, D.6
  • 25
    • 67749089562 scopus 로고    scopus 로고
    • A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase
    • Mitra K., Wunder C., Roysam B., Lin G., Lippincott-Schwartz J. A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase. Proc. Natl. Acad. Sci. U S A 2009, 106:11960-11965.
    • (2009) Proc. Natl. Acad. Sci. U S A , vol.106 , pp. 11960-11965
    • Mitra, K.1    Wunder, C.2    Roysam, B.3    Lin, G.4    Lippincott-Schwartz, J.5
  • 28
    • 77957881882 scopus 로고    scopus 로고
    • Evidence for a growth-stabilizing regulatory feedback mechanism between Myc and Yorkie, the Drosophila homolog of Yap
    • Neto-Silva R.M., de Beco S., Johnston L.A. Evidence for a growth-stabilizing regulatory feedback mechanism between Myc and Yorkie, the Drosophila homolog of Yap. Dev. Cell 2010, 19:507-520.
    • (2010) Dev. Cell , vol.19 , pp. 507-520
    • Neto-Silva, R.M.1    de Beco, S.2    Johnston, L.A.3
  • 29
    • 84883488932 scopus 로고    scopus 로고
    • LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap
    • Nguyen H.B., Babcock J.T., Wells C.D., Quilliam L.A. LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap. Oncogene 2013, 32:4100-4109.
    • (2013) Oncogene , vol.32 , pp. 4100-4109
    • Nguyen, H.B.1    Babcock, J.T.2    Wells, C.D.3    Quilliam, L.A.4
  • 32
    • 84908112023 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in some triple-negative breast cancer cell lines: role of mTOR pathway and therapeutic potential
    • Pelicano H., Zhang W., Liu J., Hammoudi N., Dai J., Xu R.H., Pusztai L., Huang P. Mitochondrial dysfunction in some triple-negative breast cancer cell lines: role of mTOR pathway and therapeutic potential. Breast Cancer Res. 2014, 16:434.
    • (2014) Breast Cancer Res. , vol.16 , pp. 434
    • Pelicano, H.1    Zhang, W.2    Liu, J.3    Hammoudi, N.4    Dai, J.5    Xu, R.H.6    Pusztai, L.7    Huang, P.8
  • 36
    • 0034880458 scopus 로고    scopus 로고
    • Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue
    • Stingl J., Eaves C.J., Zandieh I., Emerman J.T. Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue. Breast Cancer Res. Treat. 2001, 67:93-109.
    • (2001) Breast Cancer Res. Treat. , vol.67 , pp. 93-109
    • Stingl, J.1    Eaves, C.J.2    Zandieh, I.3    Emerman, J.T.4
  • 37
    • 70349836305 scopus 로고    scopus 로고
    • C-Myc affects mRNA translation, cell proliferation and progenitor cell function in the mammary gland
    • Stoelzle T., Schwarb P., Trumpp A., Hynes N.E. c-Myc affects mRNA translation, cell proliferation and progenitor cell function in the mammary gland. BMC Biol. 2009, 7:63.
    • (2009) BMC Biol. , vol.7 , pp. 63
    • Stoelzle, T.1    Schwarb, P.2    Trumpp, A.3    Hynes, N.E.4
  • 38
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126:663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 39
    • 0024162530 scopus 로고
    • Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice
    • Tsukamoto A.S., Grosschedl R., Guzman R.C., Parslow T., Varmus H.E. Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice. Cell 1988, 55:619-625.
    • (1988) Cell , vol.55 , pp. 619-625
    • Tsukamoto, A.S.1    Grosschedl, R.2    Guzman, R.C.3    Parslow, T.4    Varmus, H.E.5
  • 44
    • 84925400202 scopus 로고    scopus 로고
    • Taming of the beast: shaping Myc-dependent amplification
    • Wolf E., Lin C.Y., Eilers M., Levens D.L. Taming of the beast: shaping Myc-dependent amplification. Trends Cell Biol. 2015, 25:241-248.
    • (2015) Trends Cell Biol. , vol.25 , pp. 241-248
    • Wolf, E.1    Lin, C.Y.2    Eilers, M.3    Levens, D.L.4
  • 45
    • 41449118521 scopus 로고    scopus 로고
    • Module map of stem cell genes guides creation of epithelial cancer stem cells
    • Wong D.J., Liu H., Ridky T.W., Cassarino D., Segal E., Chang H.Y. Module map of stem cell genes guides creation of epithelial cancer stem cells. Cell Stem Cell 2008, 2:333-344.
    • (2008) Cell Stem Cell , vol.2 , pp. 333-344
    • Wong, D.J.1    Liu, H.2    Ridky, T.W.3    Cassarino, D.4    Segal, E.5    Chang, H.Y.6
  • 47
    • 35948961118 scopus 로고    scopus 로고
    • Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
    • Zhao B., Wei X., Li W., Udan R.S., Yang Q., Kim J., Xie J., Ikenoue T., Yu J., Li L., et al. Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. Genes Dev. 2007, 21:2747-2761.
    • (2007) Genes Dev. , vol.21 , pp. 2747-2761
    • Zhao, B.1    Wei, X.2    Li, W.3    Udan, R.S.4    Yang, Q.5    Kim, J.6    Xie, J.7    Ikenoue, T.8    Yu, J.9    Li, L.10
  • 49
    • 73549095761 scopus 로고    scopus 로고
    • A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)
    • Zhao B., Li L., Tumaneng K., Wang C.Y., Guan K.L. A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP). Genes Dev. 2010, 24:72-85.
    • (2010) Genes Dev. , vol.24 , pp. 72-85
    • Zhao, B.1    Li, L.2    Tumaneng, K.3    Wang, C.Y.4    Guan, K.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.