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Volumn 17, Issue 4, 2015, Pages 490-499

AMPK modulates Hippo pathway activity to regulate energy homeostasis

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUCOSE; GLUCOSE TRANSPORTER 3; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LATS KINASE; MST KINASE; ONCOPROTEIN; PROTEIN KINASE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TEAD; UNCLASSIFIED DRUG; YES ASSOCIATION PROTEIN; HIPPO PROTEIN, MOUSE; LATS1 PROTEIN, MOUSE; PHOSPHOPROTEIN; PROTEIN SERINE THREONINE KINASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SLC2A3 PROTEIN, MOUSE; YAP PROTEIN, MOUSE;

EID: 84925941268     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb3113     Document Type: Article
Times cited : (428)

References (40)
  • 1
    • 77957883342 scopus 로고    scopus 로고
    • The hippo signaling pathway in development and cancer
    • Pan, D. The hippo signaling pathway in development and cancer. Dev. Cell 19, 491-505 (2010).
    • (2010) Dev. Cell , vol.19 , pp. 491-505
    • Pan, D.1
  • 2
    • 77951837150 scopus 로고    scopus 로고
    • The Hippo-YAP pathway in organ size control and tumorigenesis: An updated version
    • Zhao, B., Li, L., Lei, Q. & Guan, K. L. The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version. Genes Dev. 24, 862-874 (2010).
    • (2010) Genes Dev. , vol.24 , pp. 862-874
    • Zhao, B.1    Li, L.2    Lei, Q.3    Guan, K.L.4
  • 3
    • 78650724753 scopus 로고    scopus 로고
    • Hippo signaling: Growth control and beyond
    • Halder, G. & Johnson, R. L. Hippo signaling: growth control and beyond. Development 138, 9-22 (2011).
    • (2011) Development , vol.138 , pp. 9-22
    • Halder, G.1    Johnson, R.L.2
  • 4
    • 73549095761 scopus 로고    scopus 로고
    • A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF-TRCP
    • Zhao, B., Li, L., Tumaneng, K., Wang, C. Y. & Guan, K. L. A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF-TRCP . Genes Dev. 24, 72-85 (2010).
    • (2010) Genes Dev. , vol.24 , pp. 72-85
    • Zhao, B.1    Li, L.2    Tumaneng, K.3    Wang, C.Y.4    Guan, K.L.5
  • 5
    • 84896092147 scopus 로고    scopus 로고
    • A peptide mimicking VGLL4 function acts as a YAP antagonist therapy against gastric cancer
    • Jiao, S. et al. A peptide mimicking VGLL4 function acts as a YAP antagonist therapy against gastric cancer. Cancer Cell 25, 166-180 (2014).
    • (2014) Cancer Cell , vol.25 , pp. 166-180
    • Jiao, S.1
  • 6
    • 84897584171 scopus 로고    scopus 로고
    • VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex
    • Zhang, W. et al. VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex. Cell Res. 24, 331-343 (2014).
    • (2014) Cell Res. , vol.24 , pp. 331-343
    • Zhang, W.1
  • 7
    • 76549124517 scopus 로고    scopus 로고
    • Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver
    • Lu, L. et al. Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver. Proc. Natl Acad. Sci. USA 107, 1437-1442 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 1437-1442
    • Lu, L.1
  • 8
    • 78049451932 scopus 로고    scopus 로고
    • The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program
    • Cai, J. et al. The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program. Genes Dev. 24, 2383-2388 (2010).
    • (2010) Genes Dev. , vol.24 , pp. 2383-2388
    • Cai, J.1
  • 9
    • 77952336576 scopus 로고    scopus 로고
    • The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis
    • Lee, K. P. et al. The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis. Proc. Natl Acad. Sci. USA 107, 8248-8253 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 8248-8253
    • Lee, K.P.1
  • 10
    • 36549074631 scopus 로고    scopus 로고
    • YAP1 increases organ size and expands undifferentiated progenitor cells
    • Camargo, F. D. et al. YAP1 increases organ size and expands undifferentiated progenitor cells. Curr. Biol. 17, 2054-2060 (2007).
    • (2007) Curr. Biol. , vol.17 , pp. 2054-2060
    • Camargo, F.D.1
  • 11
    • 34548636132 scopus 로고    scopus 로고
    • Elucidation of a universal size-control mechanism in Drosophila and mammals
    • Dong, J. et al. Elucidation of a universal size-control mechanism in Drosophila and mammals. Cell 130, 1120-1133 (2007).
    • (2007) Cell , vol.130 , pp. 1120-1133
    • Dong, J.1
  • 12
    • 84901774050 scopus 로고    scopus 로고
    • The Hippo signaling pathway in stem cell biology and cancer
    • Mo, J. S., Park, H. W. & Guan, K. L. The Hippo signaling pathway in stem cell biology and cancer. EMBO Rep. 15, 642-656 (2014).
    • (2014) EMBO Rep. , vol.15 , pp. 642-656
    • Mo, J.S.1    Park, H.W.2    Guan, K.L.3
  • 13
    • 35948961118 scopus 로고    scopus 로고
    • Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
    • Zhao, B. et al. Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. Genes Dev. 21, 2747-2761 (2007).
    • (2007) Genes Dev. , vol.21 , pp. 2747-2761
    • Zhao, B.1
  • 14
    • 84855326431 scopus 로고    scopus 로고
    • Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis
    • Zhao, B. et al. Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis. Genes Dev. 26, 54-68 (2012).
    • (2012) Genes Dev. , vol.26 , pp. 54-68
    • Zhao, B.1
  • 15
    • 84865411430 scopus 로고    scopus 로고
    • Transduction of mechanical and cytoskeletal cues by YAP and TAZ
    • Halder, G., Dupont, S. & Piccolo, S. Transduction of mechanical and cytoskeletal cues by YAP and TAZ. Nat. Rev. Mol. Cell Biol. 13, 591-600 (2012).
    • (2012) Nat. Rev. Mol. Cell Biol. , vol.13 , pp. 591-600
    • Halder, G.1    Dupont, S.2    Piccolo, S.3
  • 16
    • 79958284636 scopus 로고    scopus 로고
    • Role of YAP/TAZ in mechanotransduction
    • Dupont, S. et al. Role of YAP/TAZ in mechanotransduction. Nature 474, 179-183 (2011).
    • (2011) Nature , vol.474 , pp. 179-183
    • Dupont, S.1
  • 17
    • 84865260845 scopus 로고    scopus 로고
    • Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling
    • Yu, F. X. et al. Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling. Cell 150, 780-791 (2012).
    • (2012) Cell , vol.150 , pp. 780-791
    • Yu, F.X.1
  • 18
    • 61849135453 scopus 로고    scopus 로고
    • Tumor suppressors and cell metabolism: A recipe for cancer growth
    • Jones, R. G. & Thompson, C. B. Tumor suppressors and cell metabolism: a recipe for cancer growth. Genes Dev. 23, 537-548 (2009).
    • (2009) Genes Dev. , vol.23 , pp. 537-548
    • Jones, R.G.1    Thompson, C.B.2
  • 20
    • 79251587803 scopus 로고    scopus 로고
    • Phosphorylation of ULK1 (hATG1) by AMP-Activated protein kinase connects energy sensing to mitophagy
    • Egan, D. F. et al. Phosphorylation of ULK1 (hATG1) by AMP-Activated protein kinase connects energy sensing to mitophagy. Science 331, 456-461 (2011).
    • (2011) Science , vol.331 , pp. 456-461
    • Egan, D.F.1
  • 21
    • 0032567252 scopus 로고    scopus 로고
    • Functional domains of the alpha1 catalytic subunit of the AMP-Activated protein kinase
    • Crute, B. E., Seefeld, K., Gamble, J., Kemp, B. E. & Witters, L. A. Functional domains of the alpha1 catalytic subunit of the AMP-Activated protein kinase. J. Biol. Chem. 273, 35347-35354 (1998).
    • (1998) J. Biol. Chem. , vol.273 , pp. 35347-35354
    • Crute, B.E.1    Seefeld, K.2    Gamble, J.3    Kemp, B.E.4    Witters, L.A.5
  • 22
    • 41949138130 scopus 로고    scopus 로고
    • Tumor suppressor LATS1 is a negative regulator of oncogene YAP
    • Hao, Y., Chun, A., Cheung, K., Rashidi, B. & Yang, X. Tumor suppressor LATS1 is a negative regulator of oncogene YAP. J. Biol. Chem. 283, 5496-5509 (2008).
    • (2008) J. Biol. Chem. , vol.283 , pp. 5496-5509
    • Hao, Y.1    Chun, A.2    Cheung, K.3    Rashidi, B.4    Yang, X.5
  • 23
    • 39149140364 scopus 로고    scopus 로고
    • ERK1/2 phosphorylate GEF-H1 to enhance its guanine nucleotide exchange activity toward RhoA
    • Fujishiro, S. H. et al. ERK1/2 phosphorylate GEF-H1 to enhance its guanine nucleotide exchange activity toward RhoA. Biochem. Biophys. Res. Commun. 368, 162-167 (2008).
    • (2008) Biochem. Biophys. Res. Commun. , vol.368 , pp. 162-167
    • Fujishiro, S.H.1
  • 24
    • 84901714326 scopus 로고    scopus 로고
    • Akt and RhoA activation in response to high glucose require caveolin-1 phosphorylation in mesangial cells
    • Wu, S. Z. et al. Akt and RhoA activation in response to high glucose require caveolin-1 phosphorylation in mesangial cells. Am. J. Physiol. Renal Physiol. 306, F1308-F1317 (2014).
    • (2014) Am. J. Physiol. Renal Physiol. , vol.306 , pp. F1308-F1317
    • Wu, S.Z.1
  • 25
    • 83455208473 scopus 로고    scopus 로고
    • High glucose-induced RhoA activation requires caveolae and PKCbeta1-mediated ROS generation
    • Zhang, Y., Peng, F., Gao, B., Ingram, A. J. & Krepinsky, J. C. High glucose-induced RhoA activation requires caveolae and PKCbeta1-mediated ROS generation. Am. J. Physiol. Renal Physiol. 302, F159-F172 (2012).
    • (2012) Am. J. Physiol. Renal Physiol. , vol.302 , pp. F159-F172
    • Zhang, Y.1    Peng, F.2    Gao, B.3    Ingram, A.J.4    Krepinsky, J.C.5
  • 26
    • 47549095853 scopus 로고    scopus 로고
    • TEAD mediates YAP-dependent gene induction and growth control
    • Zhao, B. et al. TEAD mediates YAP-dependent gene induction and growth control. Genes Dev. 22, 1962-1971 (2008).
    • (2008) Genes Dev. , vol.22 , pp. 1962-1971
    • Zhao, B.1
  • 27
    • 0033986761 scopus 로고    scopus 로고
    • Causes and consequences of tumour acidity and implications for treatment
    • Stubbs, M., McSheehy, P. M., Griffiths, J. R. & Bashford, C. L. Causes and consequences of tumour acidity and implications for treatment. Mol. Med. Today 6, 15-19 (2000).
    • (2000) Mol. Med. Today , vol.6 , pp. 15-19
    • Stubbs, M.1    McSheehy, P.M.2    Griffiths, J.R.3    Bashford, C.L.4
  • 28
    • 79952297528 scopus 로고    scopus 로고
    • Yes-Associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin
    • Zhang, H., Pasolli, H. A. & Fuchs, E. Yes-Associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin. Proc. Natl Acad. Sci. USA 108, 2270-2275 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 2270-2275
    • Zhang, H.1    Pasolli, H.A.2    Fuchs, E.3
  • 29
    • 0025075721 scopus 로고
    • Over-expression of facilitative glucose transporter genes in human cancer
    • Yamamoto, T. et al. Over-expression of facilitative glucose transporter genes in human cancer. Biochem. Biophys. Res. Commun. 170, 223-230 (1990).
    • (1990) Biochem. Biophys. Res. Commun. , vol.170 , pp. 223-230
    • Yamamoto, T.1
  • 30
    • 0028280535 scopus 로고
    • Expression of glucose transporters in head-And-neck tumors
    • Mellanen, P., Minn, H., Grenman, R. & Harkonen, P. Expression of glucose transporters in head-And-neck tumors. Int. J. Cancer 56, 622-629 (1994).
    • (1994) Int. J. Cancer , vol.56 , pp. 622-629
    • Mellanen, P.1    Minn, H.2    Grenman, R.3    Harkonen, P.4
  • 31
    • 0027985721 scopus 로고
    • Gene expression of GLUT3 and GLUT1 glucose transporters in human brain tumors
    • Boado, R. J., Black, K. L. & Pardridge, W. M. Gene expression of GLUT3 and GLUT1 glucose transporters in human brain tumors. Brain Res. Mol. Brain Res. 27, 51-57 (1994).
    • (1994) Brain Res. Mol. Brain Res. , vol.27 , pp. 51-57
    • Boado, R.J.1    Black, K.L.2    Pardridge, W.M.3
  • 32
    • 0030772117 scopus 로고    scopus 로고
    • Overexpression of Glut1 and Glut3 in stage i nonsmall cell lung carcinoma is associated with poor survival
    • Younes, M., Brown, R. W., Stephenson, M., Gondo, M. & Cagle, P. T. Overexpression of Glut1 and Glut3 in stage I nonsmall cell lung carcinoma is associated with poor survival. Cancer 80, 1046-1051 (1997).
    • (1997) Cancer , vol.80 , pp. 1046-1051
    • Younes, M.1    Brown, R.W.2    Stephenson, M.3    Gondo, M.4    Cagle, P.T.5
  • 33
    • 77951800160 scopus 로고    scopus 로고
    • GLUT1 and GLUT3 as potential prognostic markers for oral squamous cell carcinoma
    • Ayala, F. R. et al. GLUT1 and GLUT3 as potential prognostic markers for oral squamous cell carcinoma. Molecules 15, 2374-2387 (2010).
    • (2010) Molecules , vol.15 , pp. 2374-2387
    • Ayala, F.R.1
  • 34
    • 84869482546 scopus 로고    scopus 로고
    • CAV1/caveolin 1 enhances aerobic glycolysis in colon cancer cells via activation of SLC2A3/GLUT3 transcription
    • Ha, T. K. & Chi, S. G. CAV1/caveolin 1 enhances aerobic glycolysis in colon cancer cells via activation of SLC2A3/GLUT3 transcription. Autophagy 8, 1684-1685 (2012).
    • (2012) Autophagy , vol.8 , pp. 1684-1685
    • Ha, T.K.1    Chi, S.G.2
  • 35
    • 84925970129 scopus 로고    scopus 로고
    • Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway
    • Mo, J-S. et al. Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway. Nat. Cell Biol. 17, http://dx.doi.org/10.1038/ncb3111 (2015).
    • (2015) Nat. Cell Biol. , vol.17
    • Mo, J.-S.1
  • 36
    • 84919595168 scopus 로고    scopus 로고
    • Energy stress regulates Hippo-YAP signaling involving AMPK-mediated regulation of angiomotin-like 1 protein
    • DeRan, M. et al. Energy stress regulates Hippo-YAP signaling involving AMPK-mediated regulation of angiomotin-like 1 protein. Cell Rep. 9, 495-503 (2014).
    • (2014) Cell Rep. , vol.9 , pp. 495-503
    • Deran, M.1
  • 37
    • 0029927505 scopus 로고    scopus 로고
    • Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels
    • Shevchenko, A., Wilm, M., Vorm, O. & Mann, M. Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal. Chem. 68, 850-858 (1996).
    • (1996) Anal. Chem. , vol.68 , pp. 850-858
    • Shevchenko, A.1    Wilm, M.2    Vorm, O.3    Mann, M.4
  • 38
    • 0034757770 scopus 로고    scopus 로고
    • Proteomics: The move to mixtures
    • Peng, J. & Gygi, S. P. Proteomics: the move to mixtures. J. Mass Spectrom. 36, 1083-1091 (2001).
    • (2001) J. Mass Spectrom. , vol.36 , pp. 1083-1091
    • Peng, J.1    Gygi, S.P.2
  • 39
    • 0000857494 scopus 로고
    • An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database
    • Eng, J. K., McCormack, A. L. & Yates, J. R. An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database. J. Am. Soc. Mass Spectrom. 5, 976-989 (1994).
    • (1994) J. Am. Soc. Mass Spectrom. , vol.5 , pp. 976-989
    • Eng, J.K.1    McCormack, A.L.2    Yates, J.R.3
  • 40
    • 33749853607 scopus 로고    scopus 로고
    • A probability-based approach for high-Throughput protein phosphorylation analysis and site localization
    • Beausoleil, S. A., Villen, J., Gerber, S. A., Rush, J. & Gygi, S. P. A probability-based approach for high-Throughput protein phosphorylation analysis and site localization. Nat. Biotechnol. 24, 1285-1292 (2006).
    • (2006) Nat. Biotechnol. , vol.24 , pp. 1285-1292
    • Beausoleil, S.A.1    Villen, J.2    Gerber, S.A.3    Rush, J.4    Gygi, S.P.5


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