Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth

Nature Cell Biology

Volumn 17, Issue 9, 2015, Pages 1218-1227

  Zanconato, Francesca ^a   Forcato, Mattia ^b   Battilana, Giusy ^a   Azzolin, Luca ^a   Quaranta, Erika ^a   Bodega, Beatrice ^c   Rosato, Antonio ^a,d   Bicciato, Silvio ^b   Cordenonsi, Michelangelo ^a   Piccolo, Stefano ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^c Istituto Nazionale di Genetica Molecolare   (Italy)

^d VENETO INSTITUTE OF ONCOLOGY IOV IRCCS   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DIMER; TRANSCRIPTION FACTOR AP 1; DNA BINDING PROTEIN; NUCLEAR PROTEIN; PHOSPHOPROTEIN; PROTEIN BINDING; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TAZ PROTEIN, HUMAN; TEAD1 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; YAP1 (YES-ASSOCIATED) PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AP 1 GENE; ARTICLE; CANCER GROWTH; CELL CYCLE S PHASE; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; FEMALE; GAIN OF FUNCTION MUTATION; GENE; GENE ACTIVATION; GENE FUNCTION; GENE TARGETING; GENETIC ASSOCIATION; LOSS OF FUNCTION MUTATION; MITOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN FUNCTION; PROTEIN MOTIF; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; SKIN CANCER; SKIN CARCINOGENESIS; TAZ GENE; TEAD GENE; YAP GENE; ANIMAL; CARCINOGENESIS; ENHANCER REGION; GENE EXPRESSION REGULATION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; HEK293 CELL LINE; HUMAN; KNOCKOUT MOUSE; MALE; METABOLISM; PATHOLOGY; PHYSIOLOGY; SKIN TUMOR; TRANSCRIPTION INITIATION; TUMOR CELL LINE; TUMOR VOLUME;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CARCINOGENESIS; CELL LINE, TUMOR; DNA-BINDING PROTEINS; ENHANCER ELEMENTS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOME-WIDE ASSOCIATION STUDY; HEK293 CELLS; HUMANS; MALE; MICE, KNOCKOUT; NUCLEAR PROTEINS; PHOSPHOPROTEINS; PROTEIN BINDING; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION; TUMOR BURDEN;

EID: 84940587069     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb3216     Document Type: Article

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