Aberrant TGFβ signaling contributes to altered trophoblast differentiation in preeclampsia

Endocrinology

Volumn 157, Issue 2, 2016, Pages 883-899

  Xu, Jing ^a   Sivasubramaniyam, Tharini ^a   Yinon, Yoav ^b   Tagliaferro, Andrea ^a   Ray, Jocelyn ^a   Nevo, Ori ^b   Post, Martin ^b,c,d   Caniggia, Isabella ^a,b  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 4; SMAD2 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; CCNE1 PROTEIN, HUMAN; CDK4 PROTEIN, HUMAN; CYCLIN E; GCM1 PROTEIN, HUMAN; MESSENGER RNA; NUCLEAR PROTEIN; ONCOPROTEIN; PARD6A PROTEIN, HUMAN; PLACENTA PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SMAD2 PROTEIN, HUMAN; SMAD7 PROTEIN, HUMAN; SMURF1 PROTEIN, HUMAN; SYNCYTIN; TRANSCRIPTION FACTOR; UBIQUITIN PROTEIN LIGASE; VIRUS ENVELOPE PROTEIN;

ARTICLE; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTROPHOBLAST; DOWN REGULATION; FEMALE; FIRST TRIMESTER PREGNANCY; GESTATIONAL AGE; HUMAN; MULTIGENE FAMILY; PATHOGENESIS; PREECLAMPSIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SYNCYTIOTROPHOBLAST; TRANSIENT TRANSFECTION; TROPHOBLAST; UBIQUITINATION; WESTERN BLOTTING; ADOLESCENT; ADULT; CASE CONTROL STUDY; GENETICS; MALE; METABOLISM; NEWBORN; PHOSPHORYLATION; PLACENTA; PREGNANCY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; YOUNG ADULT;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADOLESCENT; ADULT; CASE-CONTROL STUDIES; CELL DIFFERENTIATION; CELL PROLIFERATION; CYCLIN E; CYCLIN-DEPENDENT KINASE 4; FEMALE; GENE PRODUCTS, ENV; GESTATIONAL AGE; HUMANS; INFANT, NEWBORN; MALE; NUCLEAR PROTEINS; ONCOGENE PROTEINS; PHOSPHORYLATION; PLACENTA; PRE-ECLAMPSIA; PREGNANCY; PREGNANCY PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHOA GTP-BINDING PROTEIN; RNA, MESSENGER; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD7 PROTEIN; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA; TROPHOBLASTS; UBIQUITIN-PROTEIN LIGASES; YOUNG ADULT;

EID: 84956889990     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2015-1696     Document Type: Article

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