메뉴 건너뛰기




Volumn 12, Issue 5, 2005, Pages 441-452

A novel Mtd splice isoform is responsible for trophoblast cell death in pre-eclampsia

Author keywords

Apoptosis; Matador (Mtd); Oxidative stress; Placenta; Pre eclampsia; Trophoblast

Indexed keywords

CASPASE 3; MATADOR P PROTEIN; MATADOR PROTEIN; PROTEIN BCL 2; UNCLASSIFIED DRUG;

EID: 18644363025     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401593     Document Type: Article
Times cited : (59)

References (47)
  • 2
    • 0027964281 scopus 로고
    • A study of placental bed spiral arteries and trophoblast invasion in normal ace severe pre-eclamptic pregnancies
    • Meekins JW, Pijnenborg R, Hanssens M, McFadyen IR and van Asshe A (1994) A study of placental bed spiral arteries and trophoblast invasion in normal ace severe pre-eclamptic pregnancies. Br. J. Obstet. Gynaecol. 101: 669-674
    • (1994) Br. J. Obstet. Gynaecol. , vol.101 , pp. 669-674
    • Meekins, J.W.1    Pijnenborg, R.2    Hanssens, M.3    McFadyen, I.R.4    van Asshe, A.5
  • 3
    • 0030450419 scopus 로고    scopus 로고
    • Pregnancy hypertension and uterine artery Doppler ultrasound
    • Aquilina J and Harrington K (1996) Pregnancy hypertension and uterine artery Doppler ultrasound. Curr. Opin. Obstet. Gynecol. 8: 435-440
    • (1996) Curr. Opin. Obstet. Gynecol. , vol.8 , pp. 435-440
    • Aquilina, J.1    Harrington, K.2
  • 4
    • 0033832416 scopus 로고    scopus 로고
    • Placental debris, oxidative stress and preeclampsia
    • Redman CW and Sargent IL (2000) Placental debris, oxidative stress and preeclampsia. Placenta 21: 597-602
    • (2000) Placenta , vol.21 , pp. 597-602
    • Redman, C.W.1    Sargent, I.L.2
  • 5
    • 0033523435 scopus 로고    scopus 로고
    • Is oxidative stress the link in the two-stage model of pre-eclampsia?
    • Roberts JM and Hubel CA (1999) Is oxidative stress the link in the two-stage model of pre-eclampsia? Lancet 354: 788-789
    • (1999) Lancet , vol.354 , pp. 788-789
    • Roberts, J.M.1    Hubel, C.A.2
  • 6
    • 0015393205 scopus 로고
    • On the pathogenesis of placental infarcts in pre-eclampsia
    • Brosens I and Renaer M (1972) On the pathogenesis of placental infarcts in pre-eclampsia. J. Obstet. Gynaecol. Br. Commonw. 79: 794-799
    • (1972) J. Obstet. Gynaecol. Br. Commonw. , vol.79 , pp. 794-799
    • Brosens, I.1    Renaer, M.2
  • 8
    • 0031754353 scopus 로고    scopus 로고
    • Villous cytotrophoblast regulation of the syncytial apoptotic cascade in the human placenta
    • Huppertz B, Frank HG, Kingdom JC, Reister F and Kaufmann P (1998) Villous cytotrophoblast regulation of the syncytial apoptotic cascade in the human placenta. Histochem. Cell Biol. 110: 495-508
    • (1998) Histochem. Cell Biol. , vol.110 , pp. 495-508
    • Huppertz, B.1    Frank, H.G.2    Kingdom, J.C.3    Reister, F.4    Kaufmann, P.5
  • 9
    • 0032983892 scopus 로고    scopus 로고
    • Preeclampsia is associated with widespread apoptosis of placental cytotrophoblasts within the uterine wall
    • DiFederico E, Genbacev O and Fisher SJ (1999) Preeclampsia is associated with widespread apoptosis of placental cytotrophoblasts within the uterine wall. Am. J. Pathol. 155: 293-301
    • (1999) Am. J. Pathol. , vol.155 , pp. 293-301
    • DiFederico, E.1    Genbacev, O.2    Fisher, S.J.3
  • 10
    • 0033397918 scopus 로고    scopus 로고
    • Apoptosis cascade progresses during turnover of human trophoblast: Analysis of villous cytotrophoblast and syncytial fragments in vitro
    • Huppertz B, Frank HG, Reister F, Kingdom J, Korr H and Kaufmann P (1999) Apoptosis cascade progresses during turnover of human trophoblast: analysis of villous cytotrophoblast and syncytial fragments in vitro. Lab. Invest. 79: 1687-1702
    • (1999) Lab. Invest. , vol.79 , pp. 1687-1702
    • Huppertz, B.1    Frank, H.G.2    Reister, F.3    Kingdom, J.4    Korr, H.5    Kaufmann, P.6
  • 11
    • 0033179760 scopus 로고    scopus 로고
    • BCL-2 family members and the mitochondria in apoptosis
    • Gross A, McDonnell JM and Korsmeyer SJ (1999) BCL-2 family members and the mitochondria in apoptosis. Genes Dev. 13: 1899-1911
    • (1999) Genes Dev. , vol.13 , pp. 1899-1911
    • Gross, A.1    McDonnell, J.M.2    Korsmeyer, S.J.3
  • 12
    • 0000907666 scopus 로고    scopus 로고
    • Tissue-specific Bcl-2 protein partners in apoptosis: An ovarian paradigm
    • Hsu SY and Hsueh AJ (2000) Tissue-specific Bcl-2 protein partners in apoptosis: an ovarian paradigm. Physiol. Rev. 80: 593-614
    • (2000) Physiol. Rev. , vol.80 , pp. 593-614
    • Hsu, S.Y.1    Hsueh, A.J.2
  • 15
    • 0036583261 scopus 로고    scopus 로고
    • Trophoblast apoptosis from pregnancies complicated by fetal growth restriction is associated with enhanced p53 expression
    • Levy R, Smith SD, Yusuf K, Huettner PC, Kraus FT, Sadovsky Y and Nelson DM (2002) Trophoblast apoptosis from pregnancies complicated by fetal growth restriction is associated with enhanced p53 expression. Am. J. Obstet. Gynecol. 186: 1056-1061
    • (2002) Am. J. Obstet. Gynecol. , vol.186 , pp. 1056-1061
    • Levy, R.1    Smith, S.D.2    Yusuf, K.3    Huettner, P.C.4    Kraus, F.T.5    Sadovsky, Y.6    Nelson, D.M.7
  • 16
    • 0036153117 scopus 로고    scopus 로고
    • Increased apoptosis in the syncytiotrophoblast in human term placentas complicated by either preeclampsia or intrauterine growth retardation
    • Ishihara N, Matsuo H, Murakoshi H, Laoag-Fernandez JB, Samoto T and Maruo T (2002) Increased apoptosis in the syncytiotrophoblast in human term placentas complicated by either preeclampsia or intrauterine growth retardation. Am. J. Obstet. Gynecol. 186: 158-166
    • (2002) Am. J. Obstet. Gynecol. , vol.186 , pp. 158-166
    • Ishihara, N.1    Matsuo, H.2    Murakoshi, H.3    Laoag-Fernandez, J.B.4    Samoto, T.5    Maruo, T.6
  • 17
    • 0001003612 scopus 로고    scopus 로고
    • Bok is a proapoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members
    • Hsu SY, Kaipia A, McGee E, Lomeli M and Hsueh AJ (1997) Bok is a proapoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members. Proc. Natl. Acad. Sci. USA 94: 12401-12406
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 12401-12406
    • Hsu, S.Y.1    Kaipia, A.2    McGee, E.3    Lomeli, M.4    Hsueh, A.J.5
  • 18
    • 0032502776 scopus 로고    scopus 로고
    • Mtd, a novel Bcl-2 family member activates apoptosis in the absence of heterodimerization with Bcl-2 and Bcl-XL
    • Inohara N, Ekhterae D, Garcia I, Carrio R, Merino J, Merry A, Chen S and Nunez G (1998) Mtd, a novel Bcl-2 family member activates apoptosis in the absence of heterodimerization with Bcl-2 and Bcl-XL. J. Biol. Chem. 273: 8705-8710
    • (1998) J. Biol. Chem. , vol.273 , pp. 8705-8710
    • Inohara, N.1    Ekhterae, D.2    Garcia, I.3    Carrio, R.4    Merino, J.5    Merry, A.6    Chen, S.7    Nunez, G.8
  • 19
    • 0001587938 scopus 로고    scopus 로고
    • A splicing variant of the Bcl-2 member Bok with a truncated BH3 domain induces apoptosis but does not dimerize with antiapoptotic Bcl-2 proteins in vitro
    • Hsu SY and Hsueh AJ (1998) A splicing variant of the Bcl-2 member Bok with a truncated BH3 domain induces apoptosis but does not dimerize with antiapoptotic Bcl-2 proteins in vitro. J. Biol. Chem. 273: 30139-30146
    • (1998) J. Biol. Chem. , vol.273 , pp. 30139-30146
    • Hsu, S.Y.1    Hsueh, A.J.2
  • 20
    • 0037188944 scopus 로고    scopus 로고
    • Hypoxia-reoxygenation: A potent inducer of apoptotic changes in the human placenta and possible etiological factor in preeclampsia
    • Hung TH, Skepper JN, Charnock-Jones DS and Burton GJ (2002) Hypoxia-reoxygenation: a potent inducer of apoptotic changes in the human placenta and possible etiological factor in preeclampsia. Circ. Res. 90: 1274-1281
    • (2002) Circ. Res. , vol.90 , pp. 1274-1281
    • Hung, T.H.1    Skepper, J.N.2    Charnock-Jones, D.S.3    Burton, G.J.4
  • 21
    • 0030778822 scopus 로고    scopus 로고
    • Endoglin regulates trophoblast differentiation along the invasive pathway in human placental villous explants
    • Caniggia I, Taylor CV, Ritchie JW, Lye SJ and Letarte M (1997) Endoglin regulates trophoblast differentiation along the invasive pathway in human placental villous explants. Endocrinology 138: 4977-4988
    • (1997) Endocrinology , vol.138 , pp. 4977-4988
    • Caniggia, I.1    Taylor, C.V.2    Ritchie, J.W.3    Lye, S.J.4    Letarte, M.5
  • 22
    • 0034284864 scopus 로고    scopus 로고
    • Evolutionarily conserved Bok proteins in the Bcl-2 family
    • Zhang H, Holzgreve W and De Geyter C (2000) Evolutionarily conserved Bok proteins in the Bcl-2 family. FEBS Lett. 480: 311-313
    • (2000) FEBS Lett. , vol.480 , pp. 311-313
    • Zhang, H.1    Holzgreve, W.2    De Geyter, C.3
  • 25
    • 0037331775 scopus 로고    scopus 로고
    • Differences in apoptotic susceptibility of cytotrophoblasts and syncytiotrophoblasts in normal pregnancy to those complicated with preeclampsia and intrauterine growth restriction
    • Crocker IP, Cooper S, Ong SC and Baker PN (2003) Differences in apoptotic susceptibility of cytotrophoblasts and syncytiotrophoblasts in normal pregnancy to those complicated with preeclampsia and intrauterine growth restriction. Am. J. Pathol. 162: 637-643
    • (2003) Am. J. Pathol. , vol.162 , pp. 637-643
    • Crocker, I.P.1    Cooper, S.2    Ong, S.C.3    Baker, P.N.4
  • 27
    • 0034100836 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFbeta(3)
    • Caniggia I, Mostachfi H, Winter J, Gassmann M, Lye SJ, Kuliszewski M and Post M (2001) Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFbeta(3). J. Clin. Invest. 105: 577-587
    • (2001) J. Clin. Invest. , vol.105 , pp. 577-587
    • Caniggia, I.1    Mostachfi, H.2    Winter, J.3    Gassmann, M.4    Lye, S.J.5    Kuliszewski, M.6    Post, M.7
  • 28
    • 0030879909 scopus 로고    scopus 로고
    • Regulation of human placental development by oxygen tension
    • Genbacev O, Zhou Y, Ludlow JW and Fisher SJ (1997) Regulation of human placental development by oxygen tension. Science 277: 1669-1672
    • (1997) Science , vol.277 , pp. 1669-1672
    • Genbacev, O.1    Zhou, Y.2    Ludlow, J.W.3    Fisher, S.J.4
  • 29
    • 0030026954 scopus 로고    scopus 로고
    • Hypoxia alters early gestation human cytotrophoblast differentiation/invasion in vitro and models the placental defects that occur in preeclampsia
    • Genbacev O, Joslin R, Damsky CH, Polliotti BM and Fisher SJ (1996) Hypoxia alters early gestation human cytotrophoblast differentiation/invasion in vitro and models the placental defects that occur in preeclampsia. J. Clin. Invest. 97: 540-550
    • (1996) J. Clin. Invest. , vol.97 , pp. 540-550
    • Genbacev, O.1    Joslin, R.2    Damsky, C.H.3    Polliotti, B.M.4    Fisher, S.J.5
  • 30
    • 0030893637 scopus 로고    scopus 로고
    • Role of Bag-1 in the survival and proliferation of the cytokine-dependent lymphocyte lines, Ba/F3 and Nb2
    • Clevenger CV, Thickman K, Ngo W, Chang WP, Takayama S and Reed JC (1997) Role of Bag-1 in the survival and proliferation of the cytokine-dependent lymphocyte lines, Ba/F3 and Nb2. Mol. Endocrinol. 11: 608-618
    • (1997) Mol. Endocrinol. , vol.11 , pp. 608-618
    • Clevenger, C.V.1    Thickman, K.2    Ngo, W.3    Chang, W.P.4    Takayama, S.5    Reed, J.C.6
  • 31
    • 0029843941 scopus 로고    scopus 로고
    • Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation
    • Linette GP, Li Y, Roth K and Korsmeyer SJ (1996) Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation. Proc. Natl. Acad. Sci. USA 93: 9545-9552
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 9545-9552
    • Linette, G.P.1    Li, Y.2    Roth, K.3    Korsmeyer, S.J.4
  • 32
    • 0029805403 scopus 로고    scopus 로고
    • Bcl-2 has a cell cycle inhibitory function separable from its enhancement of cell survival
    • Vairo G, Innes KM and Adams JM (1996) Bcl-2 has a cell cycle inhibitory function separable from its enhancement of cell survival. Oncogene 13: 1511-1519
    • (1996) Oncogene , vol.13 , pp. 1511-1519
    • Vairo, G.1    Innes, K.M.2    Adams, J.M.3
  • 33
    • 0035958570 scopus 로고    scopus 로고
    • BAD/BCL-[X(L)] heterodimerization leads to bypass of G0/G1 arrest
    • Chattopadhyay A, Chiang CW and Yang E (2001) BAD/BCL-[X(L)] heterodimerization leads to bypass of G0/G1 arrest. Oncogene 20:4507-4518
    • (2001) Oncogene , vol.20 , pp. 4507-4518
    • Chattopadhyay, A.1    Chiang, C.W.2    Yang, E.3
  • 34
    • 0032506810 scopus 로고    scopus 로고
    • Expression of Bcl-XS alters cytokinetics and decreases clonogenic survival in K12 rat colon carcinoma cells
    • Fridman JS, Rehemtulla A, Hofmann A, Blau HM and Maybaum J (1998) Expression of Bcl-XS alters cytokinetics and decreases clonogenic survival in K12 rat colon carcinoma cells. Oncogene 17: 2981-2991
    • (1998) Oncogene , vol.17 , pp. 2981-2991
    • Fridman, J.S.1    Rehemtulla, A.2    Hofmann, A.3    Blau, H.M.4    Maybaum, J.5
  • 36
    • 0034128782 scopus 로고    scopus 로고
    • Apoptosis in human cultured trophoblasts is enhanced by hypoxia and diminished by epidermal growth factor
    • Levy R, Smith SD, Chandler K, Sadovsky Y and Nelson DM (2000) Apoptosis in human cultured trophoblasts is enhanced by hypoxia and diminished by epidermal growth factor. Am. J. Physiol. Cell Physiol. 278: C982-C988
    • (2000) Am. J. Physiol. Cell Physiol. , vol.278
    • Levy, R.1    Smith, S.D.2    Chandler, K.3    Sadovsky, Y.4    Nelson, D.M.5
  • 37
    • 10644283807 scopus 로고    scopus 로고
    • Adriana and Luisa Castellucci Award lecture 2001. Hypoxia inducible factor-1: Oxygen regulation of trophoblast differentiation in normal and pre-eclamptic pregnancies - A review
    • Caniggia I and Winter JL (2002) Adriana and Luisa Castellucci Award lecture 2001. Hypoxia inducible factor-1: oxygen regulation of trophoblast differentiation in normal and pre-eclamptic pregnancies - a review. Placenta 23 (Suppl. A): S47-S57
    • (2002) Placenta , vol.23 , Issue.SUPPL. A
    • Caniggia, I.1    Winter, J.L.2
  • 38
    • 0035143802 scopus 로고    scopus 로고
    • Selective overexpression of the hypoxia-inducible transcription factor, HIF-2alpha, in placentas from women with preeclampsia
    • Rajakumar A, Whitelock KA, Weissfeld LA, Daftary AR, Markovic N and Conrad KP (2001) Selective overexpression of the hypoxia-inducible transcription factor, HIF-2alpha, in placentas from women with preeclampsia. Biol. Reprod. 64: 499-506
    • (2001) Biol. Reprod. , vol.64 , pp. 499-506
    • Rajakumar, A.1    Whitelock, K.A.2    Weissfeld, L.A.3    Daftary, A.R.4    Markovic, N.5    Conrad, K.P.6
  • 39
    • 0035884701 scopus 로고    scopus 로고
    • HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors
    • Sowter HM, Ratcliffe PJ, Watson P, Greenberg AH and Harris AL (2001) HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors. Cancer Res. 61: 6669-6673
    • (2001) Cancer Res. , vol.61 , pp. 6669-6673
    • Sowter, H.M.1    Ratcliffe, P.J.2    Watson, P.3    Greenberg, A.H.4    Harris, A.L.5
  • 40
    • 0034255036 scopus 로고    scopus 로고
    • Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia
    • Bruick RK (2000) Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia. Proc. Natl. Acad. Sci. USA 97: 9082-9087
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 9082-9087
    • Bruick, R.K.1
  • 42
    • 0028110809 scopus 로고
    • Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status
    • Graeber TG, Peterson IF, Tsai M, Monica K, Fornace AJ and Giaccia AJ (1994) Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status. Mol. Cell. Biol. 14: 6264-6277
    • (1994) Mol. Cell Biol. , vol.14 , pp. 6264-6277
    • Graeber, T.G.1    Peterson, I.F.2    Tsai, M.3    Monica, K.4    Fornace, A.J.5    Giaccia, A.J.6
  • 43
    • 0036551051 scopus 로고    scopus 로고
    • Diagnosis and management of preeclampsia and eclampsia
    • ACOG practice bulletin Number 33, January 2002. American College of Obstetricians and Gynecologists
    • ACOG practice bulletin (2002) Diagnosis and management of preeclampsia and eclampsia. Number 33, January 2002. American College of Obstetricians and Gynecologists. Int. J. Gynaecol. Obstet. 77: 67-75
    • (2002) Int. J. Gynaecol. Obstet. , vol.77 , pp. 67-75
  • 44
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak KJ and Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25: 402-408
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 46
    • 18644365786 scopus 로고    scopus 로고
    • Developmentally regulated expression of the pro-apoptotic Bcl-2 family member, Mtd/Bok, in oocytes and preimplantation embryos
    • Jurisicova A, Johnson AL, Casper RF and Tilly IL (2000) Developmentally regulated expression of the pro-apoptotic Bcl-2 family member, Mtd/Bok, in oocytes and preimplantation embryos. Endocr. Soc. 131: 316
    • (2000) Endocr. Soc. , vol.131 , pp. 316
    • Jurisicova, A.1    Johnson, A.L.2    Casper, R.F.3    Tilly, I.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.