Lipopolysaccharide-binding protein is bound and internalized by host cells and colocalizes with LPS in the cytoplasm: Implications for a role of LBP in intracellular LPS-signaling

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1863, Issue 4, 2016, Pages 660-672

  Kopp, Franziska ^a   Kupsch, Sarah ^a   Schromm, Andra B ^a  

^a RESEARCH CENTER BORSTEL   (Germany)

Author keywords

Lipopolysaccharide; Lipopolysaccharide binding protein; Macrophage; TLR4

Indexed keywords

ADENOSINE TRIPHOSPHATE; CASPASE; CD14 ANTIGEN; CELL RECEPTOR; INFLAMMASOME; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; LIPOPOLYSACCHARIDE BINDING PROTEIN; PROTEIN MD 2; TOLL LIKE RECEPTOR 4; TRITON X 100; ACUTE PHASE PROTEIN; CARRIER PROTEIN; LIPOPOLYSACCHARIDE-BINDING PROTEIN; MEMBRANE PROTEIN; PROTEIN BINDING; TLR4 PROTEIN, HUMAN;

ARTICLE; BINDING AFFINITY; CELL MEMBRANE; CELL STIMULATION; CELL SURFACE; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOPLASM; ENZYME ACTIVATION; FLUORESCENCE; HEK293 CELL LINE; HOST CELL; HUMAN; HUMAN CELL; IMMUNOREGULATION; INTERNALIZATION; INTRACELLULAR SIGNALING; INTRACELLULAR SPACE; INTRACELLULAR TRANSPORT; MACROPHAGE; MONOCYTE; MONONUCLEAR CELL; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN BLOOD LEVEL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN TRANSPORT; CELL CULTURE; ENDOCYTOSIS; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; TRANSPORT AT THE CELLULAR LEVEL;

ACUTE-PHASE PROTEINS; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CELLS, CULTURED; CYTOPLASM; ENDOCYTOSIS; HEK293 CELLS; HUMANS; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; MACROPHAGES; MEMBRANE GLYCOPROTEINS; PROTEIN BINDING; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; TOLL-LIKE RECEPTOR 4;

EID: 84956610291     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2016.01.015     Document Type: Article

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