Amyloid β-Protein C-Terminal Fragments: Formation of Cylindrins and β-Barrels

Journal of the American Chemical Society

Volumn 138, Issue 2, 2016, Pages 549-557

  Do, Thanh D ^a   Lapointe, Nichole E ^a   Nelson, Rebecca ^b   Krotee, Pascal ^b   Hayden, Eric Y ^c   Ulrich, Brittany ^c   Quan, Sarah ^c   Feinstein, Stuart C ^a   Teplow, David B ^c,d   Eisenberg, David ^a   Shea, Joan Emma ^a   Bowers, Michael T ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATOMIC FORCE MICROSCOPY; CELL MEMBRANES; GLYCOPROTEINS; MASS SPECTROMETRY; NEURODEGENERATIVE DISEASES; OLIGOMERS; PEPTIDES;

AGGREGATION KINETICS; ALZHEIMERS DISEASE; C-TERMINAL FRAGMENTS; COLLISION CROSS SECTIONS; COMPUTATIONAL MODEL; ION MOBILITY-MASS SPECTROMETRY; OLIGOMERIC STRUCTURE; THERAPEUTIC TARGETS;

PROTEINS;

AMYLOID BETA PROTEIN; DIGLYCINE; OLIGOMER; PEPTIDE FRAGMENT; CYLINDRIN; PLASMA PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; ATOMIC FORCE MICROSCOPY; CELL MEMBRANE; DEATH; ELECTRON MICROSCOPY; ENERGY; ION MOBILITY SPECTROMETRY; MASS SPECTROMETRY; NERVE CELL LESION; NERVE CELL NECROSIS; PROTEIN STRUCTURE; AMINO ACID SEQUENCE; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; PROTEIN CONFORMATION; TRANSMISSION ELECTRON MICROSCOPY;

AMINO ACID SEQUENCE; AMYLOID BETA-PEPTIDES; BLOOD PROTEINS; MICROSCOPY, ELECTRON, TRANSMISSION; PROTEIN CONFORMATION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84955487268     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.5b09536     Document Type: Article

References (56)

1. Hardy, J.; Selkoe, D. J. Science 2002, 297, 353 10.1126/science.1072994
2. Chiti, F.; Dobson, C. M. Annu. Rev. Biochem. 2006, 75, 333 10.1146/annurev.biochem.75.101304.123901
3. Chiti, F.; Dobson, C. M. Nat. Chem. Biol. 2008, 5, 15 10.1038/nchembio.131
4. Eisenberg, D.; Nelson, R.; Sawaya, M. R.; Balbirnie, M.; Sambashivan, S.; Ivanova, M. I.; Madsen, A. O.; Riekel, C. Acc. Chem. Res. 2006, 39, 568 10.1021/ar0500618
5. Murphy, R. M. Annu. Rev. Biomed. Eng. 2002, 4, 155 10.1146/annurev.bioeng.4.092801.094202
6. Caughey, B.; Lansbury, P. T. Annu. Rev. Neurosci. 2003, 26, 267 10.1146/annurev.neuro.26.010302.081142
7. Xue, W. F.; Hellewell, A. L.; Gosal, W. S.; Homans, S. W.; Hewitt, E. W.; Radford, S. E. J. Biol. Chem. 2009, 284, 34272 10.1074/jbc.M109.049809
8. Kayed, R.; Head, E.; Thompson, J. L.; McIntire, T. M.; Milton, S. C.; Cotman, C. W.; Glabe, C. G. Science 2003, 300, 486 10.1126/science.1079469
9. Glabe, C. G. J. Biol. Chem. 2008, 283, 29639 10.1074/jbc.R800016200
10. Krishnan, R.; Goodman, J. L.; Mukhopadhyay, S.; Pacheco, C. D.; Lemke, E. A.; Deniz, A. A.; Lindquist, S. Proc. Natl. Acad. Sci. U. S. A. 2012, 109, 11172 10.1073/pnas.1209527109
11. Kodali, R.; Wetzel, R. Curr. Opin. Struct. Biol. 2007, 17, 48 10.1016/j.sbi.2007.01.007
12. Do, T. D.; LaPointe, N. E.; Sangwan, S.; Teplow, D. B.; Feinstein, S. C.; Sawaya, M. R.; Eisenberg, D. S.; Bowers, M. T. J. Phys. Chem. B 2014, 118, 7247 10.1021/jp502473s
13. Laganowsky, A.; Liu, C.; Sawaya, M. R.; Whitelegge, J. P.; Park, J.; Zhao, M. L.; Pensalfini, A.; Soriaga, A. B.; Landau, M.; Teng, P. K.; Cascio, D.; Glabe, C.; Eisenberg, D. Science 2012, 335, 1228 10.1126/science.1213151
14. De Simone, A.; Derreumaux, P. J. Chem. Phys. 2010, 132, 165103 10.1063/1.3385470
15. Liu, C.; Zhao, M.; Jiang, L.; Cheng, P. N.; Park, J.; Sawaya, M. R.; Pensalfini, A.; Gou, D.; Berk, A. J.; Glabe, C. G.; Nowick, J.; Eisenberg, D. Proc. Natl. Acad. Sci. U. S. A. 2012, 109, 20913 10.1073/pnas.1218792109
16. Gu, L.; Liu, C.; Stroud, J. C.; Ngo, S.; Jiang, L.; Guo, Z. J. Biol. Chem. 2014, 289, 27300 10.1074/jbc.M114.569004
17. Morgado, I.; Wieligmann, K.; Bereza, M.; Ronicke, R.; Meinhardt, K.; Annamalai, K.; Baumann, M.; Wacker, J.; Hortschansky, P.; Malesevic, M.; Parthier, C.; Mawrin, C.; Schiene-Fischer, C.; Reymann, K. G.; Stubbs, M. T.; Balbach, J.; Gorlach, M.; Horn, U.; Fandrich, M. Proc. Natl. Acad. Sci. U. S. A. 2012, 109, 12503 10.1073/pnas.1206433109
18. Nelson, R.; Sawaya, M. R.; Balbirnie, M.; Madsen, A. O.; Riekel, C.; Grothe, R.; Eisenberg, D. Nature 2005, 435, 773 10.1038/nature03680
19. Sawaya, M. R.; Sambashivan, S.; Nelson, R.; Ivanova, M. I.; Sievers, S. A.; Apostol, M. I.; Thompson, M. J.; Balbirnie, M.; Wiltzius, J. J. W.; MacFarlane, H. T.; Madsen, A. Ø.; Riekel, C.; Eisenberg, D. Nature 2007, 447, 453 10.1038/nature05695
20. Apostol, M. I.; Perry, K.; Surewicz, W. K. J. Am. Chem. Soc. 2013, 135, 10202 10.1021/ja403001q
21. Pham, J. D.; Chim, N.; Goulding, C. W.; Nowick, J. S. J. Am. Chem. Soc. 2013, 135, 12460 10.1021/ja4068854
22. Spencer, R. K.; Li, H.; Nowick, J. S. J. Am. Chem. Soc. 2014, 136, 5595 10.1021/ja5017409
23. Bleiholder, C.; Do, T. D.; Wu, C.; Economou, N. J.; Bernstein, S. S.; Buratto, S. K.; Shea, J.-E.; Bowers, M. T. J. Am. Chem. Soc. 2013, 135, 16926 10.1021/ja406197f
24. Bernstein, S. L.; Dupuis, N. F.; Lazo, N. D.; Wyttenbach, T.; Condron, M. M.; Bitan, G.; Teplow, D. B.; Shea, J.-E.; Ruotolo, B. T.; Robinson, C. V.; Bowers, M. T. Nat. Chem. 2009, 1, 326 10.1038/nchem.247
25. Bleiholder, C.; Dupuis, N. F.; Wyttenbach, T.; Bowers, M. T. Nat. Chem. 2011, 3, 172 10.1038/nchem.945
26. Uetrecht, C.; Versluis, C.; Watts, N. R.; Roos, W. H.; Wuite, G. J. L.; Wingfield, P. T.; Steven, A. C.; Heck, A. J. R. Proc. Natl. Acad. Sci. U. S. A. 2008, 105, 9216 10.1073/pnas.0800406105
27. Pierson, E. E.; Keifer, D. Z.; Selzer, L.; Lee, L. S.; Contino, N. C.; Wang, J. C.; Zlotnick, A.; Jarrold, M. F. J. Am. Chem. Soc. 2014, 136, 3536 10.1021/ja411460w
28. Laganowsky, A.; Reading, E.; Allison, T. M.; Ulmschneider, M. B.; Degiacomi, M. T.; Baldwin, A. J.; Robinson, C. V. Nature 2014, 510, 172 10.1038/nature13419
29. Benesch, J. L. P.; Ruotolo, B. T. Curr. Opin. Struct. Biol. 2011, 21, 641 10.1016/j.sbi.2011.08.002
30. Susa, A. C.; Wu, C.; Bernstein, S. L.; Dupuis, N. F.; Wang, H.; Raleigh, D. P.; Shea, J. E.; Bowers, M. T. J. Am. Chem. Soc. 2014, 136, 12912 10.1021/ja504031d
31. Shi, L. Q.; Holliday, A. E.; Shi, H. L.; Zhu, F. F.; Ewing, M. A.; Russell, D. H.; Clemmer, D. E. J. Am. Chem. Soc. 2014, 136, 12702 10.1021/ja505899g
32. Wyttenbach, T.; Pierson, N. A.; Clemmer, D. E.; Bowers, M. T. Annu. Rev. Phys. Chem. 2014, 65, 175 10.1146/annurev-physchem-040513-103644
33. Pike, C. J.; Walencewiczwasserman, A. J.; Kosmoski, J.; Cribbs, D. H.; Glabe, C. G.; Cotman, C. W. J. Neurochem. 1995, 64, 253 10.1046/j.1471-4159.1995.64010253.x
34. Kubo, T.; Nishimura, S.; Kumagae, Y.; Kaneko, I. J. Neurosci. Res. 2002, 70, 474 10.1002/jnr.10391
35. Gidden, J.; Ferzoco, A.; Baker, E. S.; Bowers, M. T. J. Am. Chem. Soc. 2004, 126, 15132 10.1021/ja046433+
36. Mason, E. A. Transport Properties of Ions in Gases, 99 th ed.; John Wiley & Sons, 1988.
37. Kemper, P. R.; Dupuis, N. F.; Bowers, M. T. Int. J. Mass Spectrom. 2009, 287, 46 10.1016/j.ijms.2009.01.012
38. Wyttenbach, T.; Kemper, P. R.; Bowers, M. T. Int. J. Mass Spectrom. 2001, 212, 13 10.1016/S1387-3806(01)00517-6
39. Bernstein, S. L.; Wyttenbach, T.; Baumketner, A.; Shea, J.-E.; Bitan, G.; Teplow, D. B.; Bowers, M. T. J. Am. Chem. Soc. 2005, 127, 2075 10.1021/ja044531p
40. Hou, L. M.; Kang, I.; Marchant, R. E.; Zagorski, M. G. J. Biol. Chem. 2002, 277, 40173 10.1074/jbc.C200338200
41. Larini, L.; Shea, J. E. Biophys. J. 2012, 103, 576 10.1016/j.bpj.2012.06.027
42. Guex, N.; Peitsch, M. C. Electrophoresis 1997, 18, 2714 10.1002/elps.1150181505
43. Johansson, M. U.; Zoete, V.; Michielin, O.; Guex, N. BMC Bioinf. 2012, 13, 173 10.1186/1471-2105-13-173
44. Hess, B.; Kutzner, C.; Spoel, D. v. d.; Lindahl, E. J. Chem. Theory Comput. 2008, 4, 435 10.1021/ct700301q
45. Spoel, D. V. D.; Lindahl, E.; Hess, B.; Groenhof, G.; Mark, A. E.; Berendsen, H. J. C. J. Comput. Chem. 2005, 26, 1701 10.1002/jcc.20291
46. Shvartsburg, A. A.; Jarrold, M. F. Chem. Phys. Lett. 1996, 261, 86 10.1016/0009-2614(96)00941-4
47. Mesleh, M. F.; Hunter, J. M.; Shvartsburg, A. A.; Schatz, G. C.; Jarrold, M. F. J. Phys. Chem. 1996, 100, 16082 10.1021/jp961623v
48. Bleiholder, C.; Wyttenbach, T.; Bowers, M. T. Int. J. Mass Spectrom. 2011, 308, 1 10.1016/j.ijms.2011.06.014
49. Bleiholder, C.; Contreras, S.; Do, T. D.; Bowers, M. T. Int. J. Mass Spectrom. 2013, 345, 89 10.1016/j.ijms.2012.08.027
50. Colletier, J.-P.; Laganowsky, A.; Landau, M.; Zhao, M.; Soriaga, A. B.; Goldschmidt, L.; Flot, D.; Cascio, D.; Sawaya, M. R.; Eisenberg, D. Proc. Natl. Acad. Sci. U. S. A. 2011, 108, 16938 10.1073/pnas.1112600108
51. Do, T. D.; Kincannon, W. M.; Bowers, M. T. J. Am. Chem. Soc. 2015, 137, 10080 10.1021/jacs.5b05482
52. Groveman, B. R.; Dolan, M. A.; Taubner, L. M.; Kraus, A.; Wickner, R. B.; Caughey, B. J. Biol. Chem. 2014, 289, 24129 10.1074/jbc.M114.578344
53. Murzin, A. G.; Lesk, A. M.; Chothia, C. J. Mol. Biol. 1994, 236, 1369 10.1016/0022-2836(94)90064-7
54. Jang, H.; Arce, F. T.; Ramachandran, S.; Capone, R.; Lal, R.; Nussinov, R. J. Mol. Biol. 2010, 404, 917 10.1016/j.jmb.2010.10.025
55. Chang, Z.; Luo, Y.; Zhang, Y.; Wei, G. J. Phys. Chem. B 2011, 115, 1165 10.1021/jp107558e
56. Jang, H. B.; Zheng, J.; Lal, R.; Nussinov, R. Trends Biochem. Sci. 2008, 33, 91 10.1016/j.tibs.2007.10.007