The fibroblast Tiam1-osteopontin pathway modulates breast cancer invasion and metastasis

Breast Cancer Research

Volumn 18, Issue 1, 2016, Pages

  Xu, Kun ^a   Tian, Xuejun ^a   Oh, Sun Y ^a   Movassaghi, Mohammad ^b   Naber, Stephen P ^a   Kuperwasser, Charlotte ^a,c   Buchsbaum, Rachel J ^a  

^a TUFTS MEDICAL CENTER   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Agelastatin; Breast cancer; Cancer associated fibroblast; Metastasis; Osteopontin; Tiam1

Indexed keywords

CELL PROTEIN; FIBRONECTIN; NERVE CELL ADHESION MOLECULE; OSTEOPONTIN; TIAM1 PROTEIN; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR TWIST; UNCLASSIFIED DRUG; UVOMORULIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; TIAM1 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; BREAST METASTASIS; CANCER STEM CELL; CELL MIGRATION; CELL POPULATION; CELL SELF-RENEWAL; CONTROLLED STUDY; E CADHERIN GENE; EPITHELIAL MESENCHYMAL TRANSITION; FIBROBLAST; FIBRONECTIN GENE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG METASTASIS; MOUSE; N CADHERIN GENE; NONHUMAN; OPN GENE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; SLUG GENE; SNAIL GENE; TUMOR INVASION; TUMOR MICROENVIRONMENT; TWIST GENE; ANIMAL; BIOSYNTHESIS; BREAST TUMOR; COCULTURE; DRUG SCREENING; FEMALE; GENETICS; LUNG TUMOR; METABOLISM; METASTASIS; PATHOLOGY; SECONDARY; STROMA CELL; TUMOR CELL LINE;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; COCULTURE TECHNIQUES; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; FIBROBLASTS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; LUNG NEOPLASMS; MICE; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; OSTEOPONTIN; SIGNAL TRANSDUCTION; STROMAL CELLS; TUMOR MICROENVIRONMENT; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84955476179     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/s13058-016-0674-8     Document Type: Article

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