The RacGEF Tiam1 inhibits migration and invasion of metastatic melanoma via a novel adhesive mechanism

Journal of Cell Science

Volumn 117, Issue 20, 2004, Pages 4863-4871

  Uhlenbrock, Katharina ^a   Eberth, Alexander ^a   Herbrand, Ulrike ^a   Daryab, Neda ^b   Stege, Patricia ^a   Meier, Friedegund ^c   Friedl, Peter ^b   Collard, John G ^d   Ahmadian, Mohammad Reza ^a  

^a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

Actin cytoskeleton; Cell adhesion; GEF; Invasion; Melanoma; Migration; Small GTPase; Tiam1

Indexed keywords

ACTIN; ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE; CADHERIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; RAC PROTEIN; RHO FACTOR;

ARTICLE; CANCER INVASION; CELL ADHESION; CELL INTERACTION; CELL JUNCTION; CELL MIGRATION; CELL SHAPE; CELL TRANSFORMATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EPITHELIUM CELL; FIBROBLAST; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MELANOMA CELL; METASTASIS POTENTIAL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ACTIVATED-LEUKOCYTE CELL ADHESION MOLECULE; ANIMALS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; MELANOMA; NEOPLASM INVASIVENESS; PROTEINS; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION;

EID: 7244251723     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.01367     Document Type: Article

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