메뉴 건너뛰기




Volumn 7, Issue 3, 2008, Pages 548-558

Agelastatin A: A novel inhibitor of osteopontin-mediated adhesion, invasion, and colony formation

Author keywords

[No Author keywords available]

Indexed keywords

AGELASTATIN A; ANTINEOPLASTIC AGENT; BETA CATENIN; OSTEOPONTIN; RNA; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR 4; UNCLASSIFIED DRUG;

EID: 41649087976     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-07-2251     Document Type: Article
Times cited : (76)

References (53)
  • 1
    • 0025107259 scopus 로고
    • The pattern of metastases in human breast cancer: Methodological aspects and influence of prognostic factors
    • Kamby C. The pattern of metastases in human breast cancer: methodological aspects and influence of prognostic factors. Cancer Treat Rev 1990;17:37-61.
    • (1990) Cancer Treat Rev , vol.17 , pp. 37-61
    • Kamby, C.1
  • 2
    • 0037096898 scopus 로고    scopus 로고
    • Prognostic significance of the metastasis-associated protein osteopontin in human breast cancer
    • Rudland PS, Platt-Higgins A, El-Tanani M, et al. Prognostic significance of the metastasis-associated protein osteopontin in human breast cancer. Cancer Res 2002;62:3417-27.
    • (2002) Cancer Res , vol.62 , pp. 3417-3427
    • Rudland, P.S.1    Platt-Higgins, A.2    El-Tanani, M.3
  • 3
    • 0035878739 scopus 로고    scopus 로고
    • Metastasis-inducing DNA regulates the expression of the osteopontin gene by binding the transcription factor Tcf-4
    • El-Tanani M, Barraclough R, Wilkinson MC, Rudland PS. Metastasis-inducing DNA regulates the expression of the osteopontin gene by binding the transcription factor Tcf-4. Cancer Res 2001;61:5619-29.
    • (2001) Cancer Res , vol.61 , pp. 5619-5629
    • El-Tanani, M.1    Barraclough, R.2    Wilkinson, M.C.3    Rudland, P.S.4
  • 4
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • Polakis P. Wnt signaling and cancer. Genes Dev 2000;14:1837-51.
    • (2000) Genes Dev , vol.14 , pp. 1837-1851
    • Polakis, P.1
  • 5
    • 0033054464 scopus 로고    scopus 로고
    • The oncogenic activation of β-catenin
    • Polakis P. The oncogenic activation of β-catenin. Curr Opin Genet Dev 1999;9:15-21.
    • (1999) Curr Opin Genet Dev , vol.9 , pp. 15-21
    • Polakis, P.1
  • 6
    • 1642512639 scopus 로고    scopus 로고
    • Small-molecule antagonists of the oncogenic Tcf/β-catenin protein complex
    • Lepourcelet M, Chen YN, France DS, et al. Small-molecule antagonists of the oncogenic Tcf/β-catenin protein complex. Cancer Cell 2004;5:91-102.
    • (2004) Cancer Cell , vol.5 , pp. 91-102
    • Lepourcelet, M.1    Chen, Y.N.2    France, D.S.3
  • 8
    • 0035114470 scopus 로고    scopus 로고
    • Comprehensive gene expression profile of human activated T(h)1- and T(h)2-polarized cells
    • Nagai S, Hashimoto S, Yamashita T, et al. Comprehensive gene expression profile of human activated T(h)1- and T(h)2-polarized cells. Int Immunol 2001;13:367-76.
    • (2001) Int Immunol , vol.13 , pp. 367-376
    • Nagai, S.1    Hashimoto, S.2    Yamashita, T.3
  • 9
    • 0036033239 scopus 로고    scopus 로고
    • Regulation of epithelial cell migration and tumor formation by β-catenin signaling
    • Muller T, Bain G, Wang X, Papkoff J. Regulation of epithelial cell migration and tumor formation by β-catenin signaling. Exp Cell Res 2002;280:119-33.
    • (2002) Exp Cell Res , vol.280 , pp. 119-133
    • Muller, T.1    Bain, G.2    Wang, X.3    Papkoff, J.4
  • 10
    • 30844456008 scopus 로고    scopus 로고
    • Adding pharmacogenomics to the development of new marine-derived anticancer agents
    • Jimeno J, Aracil M, Tercero JC. Adding pharmacogenomics to the development of new marine-derived anticancer agents. J Transl Med 2006;4:3.
    • (2006) J Transl Med , vol.4 , pp. 3
    • Jimeno, J.1    Aracil, M.2    Tercero, J.C.3
  • 11
    • 0027170397 scopus 로고
    • Agelastatin A, a new skeleton cytotoxic alkaloid of the oroidin family. isolation from the axinellid sponge Agelas dendromorpha of the coral sea
    • D'Ambrosio M, Guerriero A, Debitus C, et al. Agelastatin A, a new skeleton cytotoxic alkaloid of the oroidin family. isolation from the axinellid sponge Agelas dendromorpha of the coral sea. J Chem Soc Chem Commun 1993:1305.
    • (1993) J Chem Soc Chem Commun , pp. 1305
    • D'Ambrosio, M.1    Guerriero, A.2    Debitus, C.3
  • 12
    • 0028116772 scopus 로고
    • Conformational preferences of agelastatin A, a cytotoxic alkaloid of the axinellid sponge Agelas dendromorpha from the coral sea, via combined molecular modeling, NMR and exciton splitting for diamide and hydroxyamide derivatives
    • Guerriero A, D'Ambrosio M, Chiasera G, Pietra F. Conformational preferences of agelastatin A, a cytotoxic alkaloid of the axinellid sponge Agelas dendromorpha from the coral sea, via combined molecular modeling, NMR and exciton splitting for diamide and hydroxyamide derivatives. Helvetica Chimica Acta 1994;79:1895-902.
    • (1994) Helvetica Chimica Acta , vol.79 , pp. 1895-1902
    • Guerriero, A.1    D'Ambrosio, M.2    Chiasera, G.3    Pietra, F.4
  • 13
    • 0029904176 scopus 로고    scopus 로고
    • The active centres of agelastatin A, a strongly cytotoxic alkaloid of the coral sea axinellid sponge Agelas dendromorpha, as determined by comparative bioassays with semisynthetic derivatives
    • D'Ambrosio M, Guerriero A, Ripamonti M, Debitus C, Waikedre J, Pietra F. The active centres of agelastatin A, a strongly cytotoxic alkaloid of the coral sea axinellid sponge Agelas dendromorpha, as determined by comparative bioassays with semisynthetic derivatives. Helvetica Chimica Acta 1996;79:727-35.
    • (1996) Helvetica Chimica Acta , vol.79 , pp. 727-735
    • D'Ambrosio, M.1    Guerriero, A.2    Ripamonti, M.3    Debitus, C.4    Waikedre, J.5    Pietra, F.6
  • 15
    • 41649120463 scopus 로고    scopus 로고
    • Total synthesis and mechanism of action studies on the antitumour alkaloid, (-)-agelastatin A
    • Harmata M, editor, London: Academic Press;
    • Hale KJ, Domostoj MM, El-Tanani M, Campbell FC, Mason CK. Total synthesis and mechanism of action studies on the antitumour alkaloid, (-)-agelastatin A. In: Harmata M, editor. Strategies and tactics in organic synthesis. London: Academic Press; 2005. p. 352-94.
    • (2005) Strategies and tactics in organic synthesis , pp. 352-394
    • Hale, K.J.1    Domostoj, M.M.2    El-Tanani, M.3    Campbell, F.C.4    Mason, C.K.5
  • 16
    • 4043079398 scopus 로고    scopus 로고
    • New total synthesis of the marine antitumor alkaloid (-)-agelastatin A
    • Domostoj MM, Irving E, Scheinmann F, Hale KJ. New total synthesis of the marine antitumor alkaloid (-)-agelastatin A. Org Lett 2004;6:2615-8.
    • (2004) Org Lett , vol.6 , pp. 2615-2618
    • Domostoj, M.M.1    Irving, E.2    Scheinmann, F.3    Hale, K.J.4
  • 18
    • 17544399127 scopus 로고    scopus 로고
    • The identification of metastasis-related gene products in a rodent mammary tumour model
    • Oates AJ, Barraclough R, Rudland PS. The identification of metastasis-related gene products in a rodent mammary tumour model. Biochem Soc Trans 1996;24:353S.
    • (1996) Biochem Soc Trans , vol.24
    • Oates, A.J.1    Barraclough, R.2    Rudland, P.S.3
  • 19
    • 33748749626 scopus 로고    scopus 로고
    • BRCA1 suppresses osteopontin-mediated breast cancer
    • El-Tanani MK, Campbell FC, Crowe P, et al. BRCA1 suppresses osteopontin-mediated breast cancer. J Biol Chem 2006;281:26587-601.
    • (2006) J Biol Chem , vol.281 , pp. 26587-26601
    • El-Tanani, M.K.1    Campbell, F.C.2    Crowe, P.3
  • 20
    • 2442650107 scopus 로고    scopus 로고
    • Ets gene PEA3 cooperates with β-catenin-Lef-1 and c-jun in regulation of osteopontin transcription
    • El-Tanani M, Platt-Higgins A, Rudland PS, Campbell FC. Ets gene PEA3 cooperates with β-catenin-Lef-1 and c-jun in regulation of osteopontin transcription. J Biol Chem 2004;279:20794-806.
    • (2004) J Biol Chem , vol.279 , pp. 20794-20806
    • El-Tanani, M.1    Platt-Higgins, A.2    Rudland, P.S.3    Campbell, F.C.4
  • 21
    • 2642584065 scopus 로고    scopus 로고
    • Osteopontin expression correlates with adhesive and metastatic potential in metastasis-inducing DNA-transfected rat mammary cell lines
    • Moye VE, Barraclough R, West C, Rudland PS. Osteopontin expression correlates with adhesive and metastatic potential in metastasis-inducing DNA-transfected rat mammary cell lines. Br J Cancer 2004;90:1796-802.
    • (2004) Br J Cancer , vol.90 , pp. 1796-1802
    • Moye, V.E.1    Barraclough, R.2    West, C.3    Rudland, P.S.4
  • 22
    • 0035834695 scopus 로고    scopus 로고
    • Differential modulation of transcriptional activity of estrogen receptors by direct protein-protein interactions with the T cell factor family of transcription factors
    • El-Tanani M, Fernig DG, Barraclough R, Green C, Rudland P. Differential modulation of transcriptional activity of estrogen receptors by direct protein-protein interactions with the T cell factor family of transcription factors. J Biol Chem 2001;276:41675-82.
    • (2001) J Biol Chem , vol.276 , pp. 41675-41682
    • El-Tanani, M.1    Fernig, D.G.2    Barraclough, R.3    Green, C.4    Rudland, P.5
  • 23
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp TR, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 2002;296:550-3.
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 24
    • 1642327569 scopus 로고    scopus 로고
    • Characterization of p53 wild-type and null isogenic colorectal cancer cell lines resistant to 5-fluorouracil, oxaliplatin, and irinotecan
    • Boyer J, McLean EG, Aroori S, et al. Characterization of p53 wild-type and null isogenic colorectal cancer cell lines resistant to 5-fluorouracil, oxaliplatin, and irinotecan. Clin Cancer Res 2004;10:2158-67.
    • (2004) Clin Cancer Res , vol.10 , pp. 2158-2167
    • Boyer, J.1    McLean, E.G.2    Aroori, S.3
  • 25
    • 0027131418 scopus 로고
    • Osteopontin: A protein with diverse functions
    • Denhardt DT, Guo X. Osteopontin: a protein with diverse functions. FASEB J 1993;7:1475-82.
    • (1993) FASEB J , vol.7 , pp. 1475-1482
    • Denhardt, D.T.1    Guo, X.2
  • 26
    • 0345188617 scopus 로고    scopus 로고
    • Osteopontin function in pathology: Lessons from osteopontin-deficient mice
    • Rittling SR, Denhardt DT. Osteopontin function in pathology: lessons from osteopontin-deficient mice. Exp Nephrol 1999;7:103-13.
    • (1999) Exp Nephrol , vol.7 , pp. 103-113
    • Rittling, S.R.1    Denhardt, D.T.2
  • 27
    • 0035021027 scopus 로고    scopus 로고
    • Osteopontin as a means to cope with environmental insults: Regulation of inflammation, tissue remodeling, and cell survival
    • Denhardt DT, Noda M, O'Regan AW, Pavlin D, Berman JS. Osteopontin as a means to cope with environmental insults: regulation of inflammation, tissue remodeling, and cell survival. J Clin Invest 2001;107:1055-61.
    • (2001) J Clin Invest , vol.107 , pp. 1055-1061
    • Denhardt, D.T.1    Noda, M.2    O'Regan, A.W.3    Pavlin, D.4    Berman, J.S.5
  • 28
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • Hannon GJ. RNA interference. Nature 2002;418:244-51.
    • (2002) Nature , vol.418 , pp. 244-251
    • Hannon, G.J.1
  • 29
    • 0141569812 scopus 로고    scopus 로고
    • Interfering with disease: Opportunities and roadblocks to harnessing RNA interference
    • Lieberman J, Song E, Lee SK, Shankar P. Interfering with disease: opportunities and roadblocks to harnessing RNA interference. Trends Mol Med 2003;9:397-403.
    • (2003) Trends Mol Med , vol.9 , pp. 397-403
    • Lieberman, J.1    Song, E.2    Lee, S.K.3    Shankar, P.4
  • 30
    • 33644748253 scopus 로고    scopus 로고
    • Association of S100A4 and osteopontin with specific prognostic factors and survival of patients with minimally invasive breast cancer
    • de Silva Rudland S, Martin L, Roshanlall C, et al. Association of S100A4 and osteopontin with specific prognostic factors and survival of patients with minimally invasive breast cancer. Clin Cancer Res 2006;12:1192-200.
    • (2006) Clin Cancer Res , vol.12 , pp. 1192-1200
    • de Silva Rudland, S.1    Martin, L.2    Roshanlall, C.3
  • 31
    • 0035870276 scopus 로고    scopus 로고
    • Down-regulation of β-catenin TCF signaling is linked to colonic epithelial cell differentiation
    • Mariadason JM, Bordonaro M, Aslam F, et al. Down-regulation of β-catenin TCF signaling is linked to colonic epithelial cell differentiation. Cancer Res 2001;61:3465-71.
    • (2001) Cancer Res , vol.61 , pp. 3465-3471
    • Mariadason, J.M.1    Bordonaro, M.2    Aslam, F.3
  • 32
    • 0032764717 scopus 로고    scopus 로고
    • Tumor cells are the source of osteopontin and bone sialoprotein expression in human breast cancer
    • Sharp JA, Sung V, Slavin J, Thompson EW, Henderson MA. Tumor cells are the source of osteopontin and bone sialoprotein expression in human breast cancer. Lab Invest 1999;79:869-77.
    • (1999) Lab Invest , vol.79 , pp. 869-877
    • Sharp, J.A.1    Sung, V.2    Slavin, J.3    Thompson, E.W.4    Henderson, M.A.5
  • 35
    • 0034636153 scopus 로고    scopus 로고
    • β-catenin, a novel prognostic marker for breast cancer: Its roles in cyclin D1 expression and cancer progression
    • Lin SY, Xia W, Wang JC, et al. β-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression. Proc Natl Acad Sci U S A 2000;97:4262-6.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 4262-4266
    • Lin, S.Y.1    Xia, W.2    Wang, J.C.3
  • 36
    • 13044281685 scopus 로고    scopus 로고
    • Target genes of β-catenin-T cell factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas
    • Mann B, Gelos M, Siedow A, et al. Target genes of β-catenin-T cell factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas. Proc Natl Acad Sci U S A 1999;96:1603-8.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 1603-1608
    • Mann, B.1    Gelos, M.2    Siedow, A.3
  • 37
    • 1642536445 scopus 로고    scopus 로고
    • + thymocytes regulate proliferation and cell adhesion
    • + thymocytes regulate proliferation and cell adhesion. J Immunol 2004;172:1099-1108.
    • (2004) J Immunol , vol.172 , pp. 1099-1108
    • Staal, F.J.1    Weerkamp, F.2    Baert, M.R.3
  • 38
    • 0035141323 scopus 로고    scopus 로고
    • The PEA3 subfamily of Ets transcription factors synergizes with β-catenin-LEF-1 to activate matrilysin transcription in intestinal tumours
    • Crawford HC, Fingleton B, Gustavson MD, et al. The PEA3 subfamily of Ets transcription factors synergizes with β-catenin-LEF-1 to activate matrilysin transcription in intestinal tumours. Mol Cell Biol 2001;21:1370-83.
    • (2001) Mol Cell Biol , vol.21 , pp. 1370-1383
    • Crawford, H.C.1    Fingleton, B.2    Gustavson, M.D.3
  • 39
  • 40
    • 0344442773 scopus 로고    scopus 로고
    • Crystal structure of a β-catenin/axin complex suggests a mechanism for the β-catenin destruction complex
    • Xing Y, Clements WK, Kimelman D, Xu W. Crystal structure of a β-catenin/axin complex suggests a mechanism for the β-catenin destruction complex. Genes Dev 2003;17:2753-64.
    • (2003) Genes Dev , vol.17 , pp. 2753-2764
    • Xing, Y.1    Clements, W.K.2    Kimelman, D.3    Xu, W.4
  • 41
    • 0033034120 scopus 로고    scopus 로고
    • β-TRCP couples β-catenin phosphorylation-degradation and regulates Xenopus axis formation
    • Liu C, Kato Y, Zhang Z, Do VM, Yankner BA, He X. β-TRCP couples β-catenin phosphorylation-degradation and regulates Xenopus axis formation. Proc Natl Acad Sci U S A 1999;96:6273-8.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 6273-6278
    • Liu, C.1    Kato, Y.2    Zhang, Z.3    Do, V.M.4    Yankner, B.A.5    He, X.6
  • 42
    • 0036225314 scopus 로고    scopus 로고
    • Dapper, a disheveled-associated antagonist of β-catenin and JNK signaling, is required for notochord formation
    • Cheyette BN, Waxman JS, Miller JR, et al. Dapper, a disheveled-associated antagonist of β-catenin and JNK signaling, is required for notochord formation. Dev Cell 2002;2:449-61.
    • (2002) Dev Cell , vol.2 , pp. 449-461
    • Cheyette, B.N.1    Waxman, J.S.2    Miller, J.R.3
  • 43
    • 33747014859 scopus 로고    scopus 로고
    • Growth suppression induced by Notch1 activation involves Wnt-β-catenin down-regulation in human tongue carcinoma cells
    • Duan L, Yao J, Wu X, Fan M. Growth suppression induced by Notch1 activation involves Wnt-β-catenin down-regulation in human tongue carcinoma cells. Biol Cell 2006;98:479-90.
    • (2006) Biol Cell , vol.98 , pp. 479-490
    • Duan, L.1    Yao, J.2    Wu, X.3    Fan, M.4
  • 44
    • 0035252894 scopus 로고    scopus 로고
    • Protein phosphatase 2A: A highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling
    • Janssens V, Goris J. Protein phosphatase 2A: a highly regulated family of serine/threonine phosphatases implicated in cell growth and signalling. Biochem J 2001;353:417-39.
    • (2001) Biochem J , vol.353 , pp. 417-439
    • Janssens, V.1    Goris, J.2
  • 46
    • 0037458733 scopus 로고    scopus 로고
    • The tuberin-hamartin complex negatively regulates β-catenin signaling activity
    • Mak BC, Takemaru K, Kenerson HL, Moon RT, Yeung RS. The tuberin-hamartin complex negatively regulates β-catenin signaling activity. J Biol Chem 2003;278:5947-51.
    • (2003) J Biol Chem , vol.278 , pp. 5947-5951
    • Mak, B.C.1    Takemaru, K.2    Kenerson, H.L.3    Moon, R.T.4    Yeung, R.S.5
  • 47
    • 33645835925 scopus 로고    scopus 로고
    • Thyroid hormone receptor alpha1 directly controls transcription of the β-catenin gene in intestinal epithelial cells
    • Plateroti M, Kress E, Mori JI, Samarut J. Thyroid hormone receptor alpha1 directly controls transcription of the β-catenin gene in intestinal epithelial cells. Mol Cell Biol 2006;26:3204-14.
    • (2006) Mol Cell Biol , vol.26 , pp. 3204-3214
    • Plateroti, M.1    Kress, E.2    Mori, J.I.3    Samarut, J.4
  • 48
    • 0033486152 scopus 로고    scopus 로고
    • β-catenin signaling and cancer
    • Morin PJ. β-catenin signaling and cancer. Bioessays 1999;21:1021-30.
    • (1999) Bioessays , vol.21 , pp. 1021-1030
    • Morin, P.J.1
  • 49
    • 1042269569 scopus 로고    scopus 로고
    • Enhancement of osteopontin expression in HepG2 cells by epidermal growth factor via phosphatidylinositol 3-kinase signaling pathway
    • Zhang GX, Zhao ZQ, Wang HD, Hao B. Enhancement of osteopontin expression in HepG2 cells by epidermal growth factor via phosphatidylinositol 3-kinase signaling pathway. World J Gastroenterol 2004;10:205-8.
    • (2004) World J Gastroenterol , vol.10 , pp. 205-208
    • Zhang, G.X.1    Zhao, Z.Q.2    Wang, H.D.3    Hao, B.4
  • 50
    • 22344435816 scopus 로고    scopus 로고
    • Epidermal growth factor receptor: A novel target of the Wnt/β-catenin pathway in liver
    • Tan X, Apte U, Micsenyi A, et al. Epidermal growth factor receptor: a novel target of the Wnt/β-catenin pathway in liver. Gastroenterology 2005;129:285-302.
    • (2005) Gastroenterology , vol.129 , pp. 285-302
    • Tan, X.1    Apte, U.2    Micsenyi, A.3
  • 51
    • 0034282519 scopus 로고    scopus 로고
    • Transactivation of the multidrug resistance 1 gene by T-cell factor 4/β-catenin complex in early colorectal carcinogenesis
    • Yamada T, Takaoka AS, Naishiro Y, et al. Transactivation of the multidrug resistance 1 gene by T-cell factor 4/β-catenin complex in early colorectal carcinogenesis. Cancer Res 2000;60:4761-6.
    • (2000) Cancer Res , vol.60 , pp. 4761-4766
    • Yamada, T.1    Takaoka, A.S.2    Naishiro, Y.3
  • 53
    • 13644254794 scopus 로고    scopus 로고
    • Molecular mechanisms of drug resistance
    • Longley DB, Johnston PG. Molecular mechanisms of drug resistance. J Pathol 2005;205:275-92.
    • (2005) J Pathol , vol.205 , pp. 275-292
    • Longley, D.B.1    Johnston, P.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.