NecroX-5 suppresses IgE/Ag-stimulated anaphylaxis and mast cell activation by regulating the SHP-1-Syk signaling module

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 71, Issue 2, 2016, Pages 198-209

  Li, X ^a   Kwon, O ^a   Kim, D Y ^a   Taketomi, Y ^b   Murakami, M ^b   Chang, H W ^a  

^a Yeungnam University   (South Korea)

^b TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

anti allergy compound; eicosanoids; NecroX 5; spleen tyrosine kinase; Src homology 2 domain containing phosphatase 1

Indexed keywords

BAY 61 3606; CALCIUM; FEXOFENADINE; HISTAMINE RELEASE INHIBITOR; I KAPPA B ALPHA; I KAPPA B BETA; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LAT PROTEIN; LEUKOTRIENE C4; MITOGEN ACTIVATED PROTEIN KINASE; NECROX 5; PHOSPHOLIPASE C GAMMA1; PROSTAGLANDIN D2; PROTEIN KINASE B; PROTEIN KINASE FYN; PROTEIN KINASE LYN; PROTEIN KINASE SYK; PROTEIN KINASE SYK INHIBITOR; PROTEIN TYROSINE PHOSPHATASE INHIBITOR; PROTEIN TYROSINE PHOSPHATASE SHP 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANTIGEN; ARACHIDONATE 5 LIPOXYGENASE; CYCLOOXYGENASE 2; CYTOKINE; FUSED HETEROCYCLIC RINGS; NECROX-5; PROTEIN BINDING; PROTEIN TYROSINE KINASE; SIGNAL PEPTIDE; SULFONE; SYK PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTI ALLERGIC ACTIVITY; ARTICLE; BONE MARROW DERIVED MAST CELL; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG ACTIVITY; DRUG EFFICACY; DRUG MECHANISM; DRUG TARGETING; ENZYME IMMUNOASSAY; ENZYME INHIBITION; EXPERIMENTAL SYSTEMIC ANAPHYLAXIS; GENE SILENCING; IMMUNOBLOTTING; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; MALE; MAST CELL DEGRANULATION; MOUSE; NONHUMAN; PASSIVE SKIN ANAPHYLAXIS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ANAPHYLAXIS; ANIMAL; BIOSYNTHESIS; CELL LINE; DEGRANULATION; DISEASE MODEL; DRUG EFFECTS; IMMUNOLOGY; MAST CELL; METABOLISM;

ANAPHYLAXIS; ANIMALS; ANTIGENS; ARACHIDONATE 5-LIPOXYGENASE; CALCIUM; CELL DEGRANULATION; CELL LINE; CYCLOOXYGENASE 2; CYTOKINES; DISEASE MODELS, ANIMAL; HETEROCYCLIC COMPOUNDS, 4 OR MORE RINGS; IMMUNOGLOBULIN E; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUKOTRIENE C4; MALE; MAST CELLS; MICE; PROSTAGLANDIN D2; PROTEIN BINDING; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; SULFONES; SYK KINASE;

EID: 84955412020     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/all.12786     Document Type: Article

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