SHP-1 deficient mast cells are hyperresponsive to stimulation and critical in initiating allergic inflammation in the lung

Journal of Immunology

Volumn 184, Issue 3, 2010, Pages 1180-1190

  Zhang, Li ^a,c   Oh, Sun Young ^a   Wu, Xinxing ^c   Oh, Min Hee ^a   Wu, Fan ^a   Schroeder, John T ^a   Takemoto, Clifford M ^b   Zheng, Tao ^a   Zhu, Zhou ^a  

^a JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

FC RECEPTOR; HYDROGEN PEROXIDE; INTERLEUKIN 13; INTERLEUKIN 4; LIPOPOLYSACCHARIDE; PROTEIN TYROSINE PHOSPHATASE SHP 1; STEM CELL FACTOR; AUTACOID; CYTOKINE; PTPN6 PROTEIN, MOUSE;

ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; CELL ACTIVATION; CELL COUNT; CELL DIFFERENTIATION; CELL FUNCTION; CELL MATURATION; CELL PROLIFERATION; CELL STIMULATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CROSS LINKING; CYTOKINE PRODUCTION; CYTOKINE RELEASE; INFLAMMATION; LUNG PARENCHYMA; MAST CELL; MOUSE; NONHUMAN; PHENOTYPE; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN BINDING; SIGNAL TRANSDUCTION; T LYMPHOCYTE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; ENZYMOLOGY; GENETICS; IMMUNOLOGY; IMMUNOPHENOTYPING; LUNG; METABOLISM; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY; RESPIRATORY TRACT ALLERGY; TH2 CELL; UPREGULATION;

ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; CYTOKINES; IMMUNOPHENOTYPING; INFLAMMATION MEDIATORS; LUNG; MAST CELLS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; RESPIRATORY HYPERSENSITIVITY; TH2 CELLS; UP-REGULATION;

EID: 77949325486     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0901972     Document Type: Article

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