FcεRI-induced activation by low antigen concentrations results in nuclear signals in the absence of degranulation

Molecular Immunology

Volumn 46, Issue 13, 2009, Pages 2539-2547

  Grodzki, Ana Cristina G ^a   Moon, Kyungduk D ^a   Berenstein, Elsa H ^a   Siraganian, Reuben P ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Degranulation; Fc RI; Mast cells; NFAT signaling; Signal transduction

Indexed keywords

CALCINEURIN; CYTOKINE; ENHANCED GREEN FLUORESCENT PROTEIN; IMMUNOGLOBULIN E RECEPTOR; LEUKOTRIENE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE SYK; TRANSCRIPTION FACTOR NFAT; ANTIGEN; CALCIUM; GREEN FLUORESCENT PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN TYROSINE KINASE; SIGNAL PEPTIDE; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL ACTIVATION; CELL FUNCTION; CONCENTRATION PROCESS; CONTROLLED STUDY; DEGRANULATION; GENE ACTIVATION; GENETIC TRANSFECTION; MAST CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; ANIMAL; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENETICS; IMMUNOBLOTTING; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SECRETION; TUMOR CELL LINE;

RATTUS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTIGENS; CALCIUM; CELL DEGRANULATION; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLOW CYTOMETRY; GREEN FLUORESCENT PROTEINS; IMMUNOBLOTTING; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAST CELLS; MICROSCOPY, FLUORESCENCE; NFATC TRANSCRIPTION FACTORS; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; RECEPTORS, IGE; RNA, SMALL INTERFERING; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 67650370014     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2009.05.013     Document Type: Article

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