ERK1/2 antagonize AMPK-dependent regulation of FcεRI-mediated mast cell activation and anaphylaxis

The Journal of allergy and clinical immunology

Volumn 134, Issue 3, 2014, Pages 714-721.e7

  Hwang, Seung Lark ^a   Lu, Yue ^a   Li, Xian ^a   Kim, Yong D euk ^a   Cho, You S ook ^b   Jahng, Yurndong ^a   Son, Jong Keun ^a   Lee, Youn J u ^c   Kang, Wonku ^d   Taketomi, Yoshitaka ^e   Murakami, Makoto ^e   Moon, Tae C hul ^f   Chang, Hyeun W ook ^a  

^a Yeungnam University   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

^c Catholic University of Daegu   (South Korea)

^d Chung Ang University   (South Korea)

^e TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^f UNIVERSITY OF ALBERTA   (Canada)

Author keywords

AMPK; anaphylaxis; ERK1 2; Mast cell

Indexed keywords

1,3 BUTADIENE DERIVATIVE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 5 AMINO 4 IMIDAZOLECARBOXAMIDE; 5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; AMPK ALPHA2 SUBUNIT, MOUSE; FC RECEPTOR; FCGR1 PROTEIN, MOUSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE; NITRILE; RIBONUCLEOSIDE;

ANALOGS AND DERIVATIVES; ANAPHYLAXIS; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; C57BL MOUSE; CELL CULTURE; COMPLICATION; DEGRANULATION; DRUG EFFECTS; GENETICS; HYPERSENSITIVITY; IMMUNOLOGY; KNOCKOUT MOUSE; MAST CELL; METABOLISM; MOUSE; SIGNAL TRANSDUCTION;

AMINOIMIDAZOLE CARBOXAMIDE; AMP-ACTIVATED PROTEIN KINASES; ANAPHYLAXIS; ANIMALS; BUTADIENES; CELL DEGRANULATION; CELLS, CULTURED; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HYPERSENSITIVITY; MAST CELLS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; NITRILES; RECEPTORS, IGG; RIBONUCLEOSIDES; SIGNAL TRANSDUCTION;

EID: 85027925084     PISSN: None     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2014.05.001     Document Type: Article

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