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Volumn 25, Issue 1, 2016, Pages 68-75

Clinicopathologic risk factor distributions for MLH1 promoter region methylation in CIMP-positive tumors

(12)  Levine, A Joan a   Phipps, Amanda I b,c   Baron, John A d   Buchanan, Daniel D e   Ahnen, Dennis J f   Cohen, Stacey A c,g   Lindor, Noralane M h   Newcomb, Polly A b,c   Rosty, Christophe e,i   Haile, Robert W a   Laird, Peter W j   Weisenberger, Daniel J k  


Author keywords

[No Author keywords available]

Indexed keywords

MLH1 PROTEIN, HUMAN; MUTL PROTEIN HOMOLOG 1; NUCLEAR PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TUMOR MARKER;

EID: 84955286730     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-15-0935     Document Type: Article
Times cited : (27)

References (51)
  • 2
    • 56649084987 scopus 로고    scopus 로고
    • Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample
    • Nosho K, Irahara N, Shima K, Kure S, Kirkner GJ, Schernhammer ES, et al. Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample. PLoS One 2008;3:e3698.
    • (2008) PLoS One , vol.3
    • Nosho, K.1    Irahara, N.2    Shima, K.3    Kure, S.4    Kirkner, G.J.5    Schernhammer, E.S.6
  • 3
    • 34247570795 scopus 로고    scopus 로고
    • Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample
    • Ogino S, Kawasaki T, Kirkner GJ, Kraft P, Loda M, Fuchs CS. Evaluation of markers for CpG island methylator phenotype (CIMP) in colorectal cancer by a large population-based sample. J Mol Diagn 2007;9:305-14.
    • (2007) J Mol Diagn , vol.9 , pp. 305-314
    • Ogino, S.1    Kawasaki, T.2    Kirkner, G.J.3    Kraft, P.4    Loda, M.5    Fuchs, C.S.6
  • 4
    • 24144449572 scopus 로고    scopus 로고
    • Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer
    • Samowitz WS, Albertsen H, Herrick J, Levin TR, Sweeney C, Murtaugh MA, et al. Evaluation of a large, population-based sample supports a CpG island methylator phenotype in colon cancer. Gastroenterology 2005;129:837-45.
    • (2005) Gastroenterology , vol.129 , pp. 837-845
    • Samowitz, W.S.1    Albertsen, H.2    Herrick, J.3    Levin, T.R.4    Sweeney, C.5    Murtaugh, M.A.6
  • 6
    • 33745541234 scopus 로고    scopus 로고
    • CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
    • Weisenberger DJ, Siegmund KD, Campan M, Young J, Long TI, Faasse MA, et al. CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nat Genet 2006;38:787-93.
    • (2006) Nat Genet , vol.38 , pp. 787-793
    • Weisenberger, D.J.1    Siegmund, K.D.2    Campan, M.3    Young, J.4    Long, T.I.5    Faasse, M.A.6
  • 7
    • 54249165951 scopus 로고    scopus 로고
    • Hypermethylator phenotype in sporadic colon cancer: Study on a population-based series of 582 cases
    • Barault L, Charon-Barra C, Jooste V, de la Vega MF, Martin L, Roignot P, et al. Hypermethylator phenotype in sporadic colon cancer: study on a population-based series of 582 cases. Cancer Res 2008;68:8541-6.
    • (2008) Cancer Res , vol.68 , pp. 8541-8546
    • Barault, L.1    Charon-Barra, C.2    Jooste, V.3    De La Vega, M.F.4    Martin, L.5    Roignot, P.6
  • 8
    • 55849140517 scopus 로고    scopus 로고
    • Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screening
    • Poynter JN, Siegmund KD, Weisenberger DJ, Long TI, Thibodeau SN, Lindor N, et al. Molecular characterization of MSI-H colorectal cancer by MLHI promoter methylation, immunohistochemistry, and mismatch repair germline mutation screening. Cancer Epidemiol Biomarkers Prev 2008;17:3208-15.
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , pp. 3208-3215
    • Poynter, J.N.1    Siegmund, K.D.2    Weisenberger, D.J.3    Long, T.I.4    Thibodeau, S.N.5    Lindor, N.6
  • 10
    • 84875551747 scopus 로고    scopus 로고
    • Mlh1 promoter methylation frequency in colorectal cancer patients and related clinico-pathological and molecular features
    • Li X, Yao X, Wang Y, Hu F, Wang F, Jiang L, et al. Mlh1 promoter methylation frequency in colorectal cancer patients and related clinico-pathological and molecular features. PLoS One 2013;8:e59064.
    • (2013) PLoS One , vol.8
    • Li, X.1    Yao, X.2    Wang, Y.3    Hu, F.4    Wang, F.5    Jiang, L.6
  • 11
    • 84879946650 scopus 로고    scopus 로고
    • Subsets of microsatellite-unstable colorectal cancers exhibit discordance between the CpG island methylator phenotype and MLH1 methylation status
    • Kim JH, Rhee YY, Bae JM, Kwon HJ, Cho NY, Kim MJ, et al. Subsets of microsatellite-unstable colorectal cancers exhibit discordance between the CpG island methylator phenotype and MLH1 methylation status. Mod Pathol 2013;26:1013-22.
    • (2013) Mod Pathol , vol.26 , pp. 1013-1022
    • Kim, J.H.1    Rhee, Y.Y.2    Bae, J.M.3    Kwon, H.J.4    Cho, N.Y.5    Kim, M.J.6
  • 12
    • 67650385667 scopus 로고    scopus 로고
    • MGMT and MLH1 promoter methylation versus APC, KRAS and BRAF gene mutations in colorectal cancer: Indications for distinct pathways and sequence of events
    • de Vogel S, Weijenberg MP, Herman JG, Wouters KA, de Goeij AF, van den Brandt PA, et al. MGMT and MLH1 promoter methylation versus APC, KRAS and BRAF gene mutations in colorectal cancer: indications for distinct pathways and sequence of events. Ann Oncol 2009;20:1216-22.
    • (2009) Ann Oncol , vol.20 , pp. 1216-1222
    • De Vogel, S.1    Weijenberg, M.P.2    Herman, J.G.3    Wouters, K.A.4    De Goeij, A.F.5    Van Den Brandt, P.A.6
  • 13
    • 77952243371 scopus 로고    scopus 로고
    • Polymorphisms in methyl-group metabolism genes and risk of sporadic colorectal cancer with relation to the CpG island methylator phenotype
    • Karpinski P, Myszka A, Ramsey D, Misiak B, Gil J, Laczmanska I, et al. Polymorphisms in methyl-group metabolism genes and risk of sporadic colorectal cancer with relation to the CpG island methylator phenotype. Cancer Epidemiol 2010;34:338-44.
    • (2010) Cancer Epidemiol , vol.34 , pp. 338-344
    • Karpinski, P.1    Myszka, A.2    Ramsey, D.3    Misiak, B.4    Gil, J.5    Laczmanska, I.6
  • 14
    • 84872842789 scopus 로고    scopus 로고
    • MLH1-silenced and non-silenced subgroups of hypermutated colorectal carcinomas have distinct mutational landscapes
    • Donehower LA, Creighton CJ, Schultz N, Shinbrot E, Chang K, Gunaratne PH, et al. MLH1-silenced and non-silenced subgroups of hypermutated colorectal carcinomas have distinct mutational landscapes. J Pathol 2013;229:99-110.
    • (2013) J Pathol , vol.229 , pp. 99-110
    • Donehower, L.A.1    Creighton, C.J.2    Schultz, N.3    Shinbrot, E.4    Chang, K.5    Gunaratne, P.H.6
  • 16
    • 38849170356 scopus 로고    scopus 로고
    • Colon cancer family registry: An international resource for studies of the genetic epidemiology of colon cancer
    • Newcomb PA, Baron J, Cotterchio M, Gallinger S, Grove J, Haile R, et al. Colon cancer family registry: an international resource for studies of the genetic epidemiology of colon cancer. Cancer Epidemiol Biomarkers Prev 2007;16:2331-43.
    • (2007) Cancer Epidemiol Biomarkers Prev , vol.16 , pp. 2331-2343
    • Newcomb, P.A.1    Baron, J.2    Cotterchio, M.3    Gallinger, S.4    Grove, J.5    Haile, R.6
  • 17
    • 80054785997 scopus 로고    scopus 로고
    • Epigenetic subgroups of esophageal and gastric adenocarcinoma with differential GATA5 DNA methylation associated with clinical and lifestyle factors
    • Wang X, Kang GH, Campan M, Weisenberger DJ, Long TI, Cozen W, et al. Epigenetic subgroups of esophageal and gastric adenocarcinoma with differential GATA5 DNA methylation associated with clinical and lifestyle factors. PLoS One 2011;6:e25985.
    • (2011) PLoS One , vol.6
    • Wang, X.1    Kang, G.H.2    Campan, M.3    Weisenberger, D.J.4    Long, T.I.5    Cozen, W.6
  • 18
    • 77955401777 scopus 로고    scopus 로고
    • Risk factors for colorectal cancer in patients with multiple serrated polyps: A cross-sectional case series from genetics clinics
    • Buchanan DD, Sweet K, Drini M, Jenkins MA, Win AK, English DR, et al. Risk factors for colorectal cancer in patients with multiple serrated polyps: a cross-sectional case series from genetics clinics. PLoS One 2010;5:e11636.
    • (2010) PLoS One , vol.5
    • Buchanan, D.D.1    Sweet, K.2    Drini, M.3    Jenkins, M.A.4    Win, A.K.5    English, D.R.6
  • 19
    • 84863984775 scopus 로고    scopus 로고
    • Kras mutations in ovarian low-grade endometrioid adenocarcinoma: Association with concurrent endometriosis
    • Stewart CJ, Leung Y, Walsh MD, Walters RJ, Young JP, Buchanan DD. Kras mutations in ovarian low-grade endometrioid adenocarcinoma: association with concurrent endometriosis. Hum Pathol 2012;43:1177-83.
    • (2012) Hum Pathol , vol.43 , pp. 1177-1183
    • Stewart, C.J.1    Leung, Y.2    Walsh, M.D.3    Walters, R.J.4    Young, J.P.5    Buchanan, D.D.6
  • 20
    • 64549130910 scopus 로고    scopus 로고
    • The association of tumor microsatellite instability phenotype with family history of colorectal cancer
    • Bapat B, Lindor NM, Baron J, Siegmund K, Li L, Zheng Y, et al. The association of tumor microsatellite instability phenotype with family history of colorectal cancer. Cancer Epidemiol Biomarkers Prev 2009;18:967-75.
    • (2009) Cancer Epidemiol Biomarkers Prev , vol.18 , pp. 967-975
    • Bapat, B.1    Lindor, N.M.2    Baron, J.3    Siegmund, K.4    Li, L.5    Zheng, Y.6
  • 21
    • 84876804457 scopus 로고    scopus 로고
    • Absence of PMS2 mutations in colon-CFR participants whose colorectal cancers demonstrate unexplained loss of mlh1 expression
    • Clendenning M, Macrae FA, Walsh MD, Walters RJ, Thibodeau SN, Gunawardena SR, et al. Absence of PMS2 mutations in colon-CFR participants whose colorectal cancers demonstrate unexplained loss of mlh1 expression. Clin Genet 2013;83:591-3.
    • (2013) Clin Genet , vol.83 , pp. 591-593
    • Clendenning, M.1    Macrae, F.A.2    Walsh, M.D.3    Walters, R.J.4    Thibodeau, S.N.5    Gunawardena, S.R.6
  • 22
    • 84860605783 scopus 로고    scopus 로고
    • Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation: A prospective cohort study
    • Win AK, Young JP, Lindor NM, Tucker KM, Ahnen DJ, Young GP, et al. Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation: a prospective cohort study. J Clin Oncol 2012;30:958-64.
    • (2012) J Clin Oncol , vol.30 , pp. 958-964
    • Win, A.K.1    Young, J.P.2    Lindor, N.M.3    Tucker, K.M.4    Ahnen, D.J.5    Young, G.P.6
  • 23
    • 84885949060 scopus 로고    scopus 로고
    • Detection of large scale 3′ deletions in the pms2 gene amongst colon-CFR participants: Have we been missing anything?
    • Clendenning M, Walsh MD, Gelpi JB, Thibodeau SN, Lindor N, Potter JD, et al. Detection of large scale 3′ deletions in the pms2 gene amongst colon-CFR participants: have we been missing anything? Fam Cancer 2013;12:563-6.
    • (2013) Fam Cancer , vol.12 , pp. 563-566
    • Clendenning, M.1    Walsh, M.D.2    Gelpi, J.B.3    Thibodeau, S.N.4    Lindor, N.5    Potter, J.D.6
  • 24
    • 0036242782 scopus 로고    scopus 로고
    • CpG island methylation in sporadic colorectal cancers and its relationship to microsatellite instability
    • Hawkins N, Norrie M, Cheong K, Mokany E, Ku SL, Meagher A, et al. CpG island methylation in sporadic colorectal cancers and its relationship to microsatellite instability. Gastroenterology 2002;122:1376-87.
    • (2002) Gastroenterology , vol.122 , pp. 1376-1387
    • Hawkins, N.1    Norrie, M.2    Cheong, K.3    Mokany, E.4    Ku, S.L.5    Meagher, A.6
  • 25
    • 80053636272 scopus 로고    scopus 로고
    • MLH1 promoter methylation, diet, and lifestyle factors in mismatch repair deficient colorectal cancer patients from epic-Norfolk
    • Gay LJ, Arends MJ, Mitrou PN, Bowman R, Ibrahim AE, Happerfield L, et al. MLH1 promoter methylation, diet, and lifestyle factors in mismatch repair deficient colorectal cancer patients from epic-Norfolk. Nutr Cancer 2011;63:1000-10.
    • (2011) Nutr Cancer , vol.63 , pp. 1000-1010
    • Gay, L.J.1    Arends, M.J.2    Mitrou, P.N.3    Bowman, R.4    Ibrahim, A.E.5    Happerfield, L.6
  • 26
    • 84892909863 scopus 로고    scopus 로고
    • Aging and epigenetic drift: A vicious cycle
    • Issa JP. Aging and epigenetic drift: a vicious cycle. J Clin Invest 2014;124:24-9.
    • (2014) J Clin Invest , vol.124 , pp. 24-29
    • Issa, J.P.1
  • 27
    • 84928728856 scopus 로고    scopus 로고
    • Aging and DNA methylation
    • Jung M, Pfeifer GP. Aging and DNA methylation. BMC Biol 2015;13:7.
    • (2015) BMC Biol , vol.13 , pp. 7
    • Jung, M.1    Pfeifer, G.P.2
  • 28
    • 0037443773 scopus 로고    scopus 로고
    • Frequency of loss of HMLH1 expression in colorectal carcinoma increases with advancing age
    • Kakar S, Burgart LJ, Thibodeau SN, Rabe KG, Petersen GM, Goldberg RM, et al. Frequency of loss of HMLH1 expression in colorectal carcinoma increases with advancing age. Cancer 2003;97:1421-7.
    • (2003) Cancer , vol.97 , pp. 1421-1427
    • Kakar, S.1    Burgart, L.J.2    Thibodeau, S.N.3    Rabe, K.G.4    Petersen, G.M.5    Goldberg, R.M.6
  • 29
    • 0035477897 scopus 로고    scopus 로고
    • Age-related hypermethylation of the 5′ region of MLH1 in normal colonic mucosa is associated with microsatellite-unstable colorectal cancer development
    • Nakagawa H, Nuovo GJ, Zervos EE, Martin EW Jr., Salovaara R, Aaltonen LA, et al. Age-related hypermethylation of the 5′ region of MLH1 in normal colonic mucosa is associated with microsatellite-unstable colorectal cancer development. Cancer Res 2001;61:6991-5.
    • (2001) Cancer Res , vol.61 , pp. 6991-6995
    • Nakagawa, H.1    Nuovo, G.J.2    Zervos, E.E.3    Martin, E.W.4    Salovaara, R.5    Aaltonen, L.A.6
  • 30
    • 73449118889 scopus 로고    scopus 로고
    • Prognostic implications of CpG island hypermethylator phenotype in colorectal cancers
    • Kim JH, Shin SH, Kwon HJ, Cho NY, Kang GH. Prognostic implications of CpG island hypermethylator phenotype in colorectal cancers. Virchows Arch 2009;455:485-94.
    • (2009) Virchows Arch , vol.455 , pp. 485-494
    • Kim, J.H.1    Shin, S.H.2    Kwon, H.J.3    Cho, N.Y.4    Kang, G.H.5
  • 31
    • 79959992817 scopus 로고    scopus 로고
    • Differential clinicopathological features in microsatellite instability-positive colorectal cancers depending on CIMP status
    • Bae JM, Kim MJ, Kim JH, Koh JM, Cho NY, Kim TY, et al. Differential clinicopathological features in microsatellite instability-positive colorectal cancers depending on CIMP status. Virchows Arch 2011;459:55-63.
    • (2011) Virchows Arch , vol.459 , pp. 55-63
    • Bae, J.M.1    Kim, M.J.2    Kim, J.H.3    Koh, J.M.4    Cho, N.Y.5    Kim, T.Y.6
  • 32
    • 84923698905 scopus 로고    scopus 로고
    • The role of the CpG island methylator phenotype on survival outcome in colon cancer
    • Kang KJ, Min BH, Ryu KJ, Kim KM, Chang DK, Kim JJ, et al. The role of the CpG island methylator phenotype on survival outcome in colon cancer. Gut Liver 2014;9:202-7.
    • (2014) Gut Liver , vol.9 , pp. 202-207
    • Kang, K.J.1    Min, B.H.2    Ryu, K.J.3    Kim, K.M.4    Chang, D.K.5    Kim, J.J.6
  • 33
    • 38149135181 scopus 로고    scopus 로고
    • Clinicopathological features of CpG island methylator phenotype-positive colorectal cancer and its adverse prognosis in relation to KRAS/BRAF mutation
    • Lee S, Cho NY, Choi M, Yoo EJ, Kim JH, Kang GH. Clinicopathological features of CpG island methylator phenotype-positive colorectal cancer and its adverse prognosis in relation to KRAS/BRAF mutation. Pathol Int 2008;58:104-13.
    • (2008) Pathol Int , vol.58 , pp. 104-113
    • Lee, S.1    Cho, N.Y.2    Choi, M.3    Yoo, E.J.4    Kim, J.H.5    Kang, G.H.6
  • 34
    • 79961137937 scopus 로고    scopus 로고
    • The CpG island methylator phenotype may confer a survival benefit in patients with stage ii or iii colorectal carcinomas receiving fluoropyrimidine-based adjuvant chemotherapy
    • Min BH, Bae JM, Lee EJ, Yu HS, Kim YH, Chang DK, et al. The CpG island methylator phenotype may confer a survival benefit in patients with stage ii or iii colorectal carcinomas receiving fluoropyrimidine-based adjuvant chemotherapy. BMC Cancer 2011;11:344.
    • (2011) BMC Cancer , vol.11 , pp. 344
    • Min, B.H.1    Bae, J.M.2    Lee, E.J.3    Yu, H.S.4    Kim, Y.H.5    Chang, D.K.6
  • 36
    • 78650215860 scopus 로고    scopus 로고
    • Two groups of DNA methylation markers to classify colorectal cancer into three epigenotypes
    • Kaneda A, Yagi K. Two groups of DNA methylation markers to classify colorectal cancer into three epigenotypes. Cancer Sci 2011;102:18-24.
    • (2011) Cancer Sci , vol.102 , pp. 18-24
    • Kaneda, A.1    Yagi, K.2
  • 37
    • 33749069927 scopus 로고    scopus 로고
    • CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: Possible associations with male sex and KRAS mutations
    • Ogino S, Kawasaki T, Kirkner GJ, Loda M, Fuchs CS. CpG island methylator phenotype-low (CIMP-low) in colorectal cancer: possible associations with male sex and KRAS mutations. J Mol Diagn 2006;8:582-8.
    • (2006) J Mol Diagn , vol.8 , pp. 582-588
    • Ogino, S.1    Kawasaki, T.2    Kirkner, G.J.3    Loda, M.4    Fuchs, C.S.5
  • 38
    • 36749025213 scopus 로고    scopus 로고
    • Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer
    • Shen L, Toyota M, Kondo Y, Lin E, Zhang L, Guo Y, et al. Integrated genetic and epigenetic analysis identifies three different subclasses of colon cancer. Proc Natl Acad Sci U S A 2007;104:18654-9.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 18654-18659
    • Shen, L.1    Toyota, M.2    Kondo, Y.3    Lin, E.4    Zhang, L.5    Guo, Y.6
  • 39
    • 78650186379 scopus 로고    scopus 로고
    • Novel application of structural equation modeling to correlation structure analysis of CpG island methylation in colorectal cancer
    • Tanaka N, Huttenhower C, Nosho K, Baba Y, Shima K, Quackenbush J, et al. Novel application of structural equation modeling to correlation structure analysis of CpG island methylation in colorectal cancer. Am J Pathol 2010;177:2731-40.
    • (2010) Am J Pathol , vol.177 , pp. 2731-2740
    • Tanaka, N.1    Huttenhower, C.2    Nosho, K.3    Baba, Y.4    Shima, K.5    Quackenbush, J.6
  • 41
    • 77957197346 scopus 로고    scopus 로고
    • Microsatellite instability as a marker of prognosis and response to therapy: A metaanalysis of colorectal cancer survival data
    • Guastadisegni C, Colafranceschi M, Ottini L, Dogliotti E. Microsatellite instability as a marker of prognosis and response to therapy: a metaanalysis of colorectal cancer survival data. Eur J Cancer 2010;46:2788-98.
    • (2010) Eur J Cancer , vol.46 , pp. 2788-2798
    • Guastadisegni, C.1    Colafranceschi, M.2    Ottini, L.3    Dogliotti, E.4
  • 42
    • 77954748953 scopus 로고    scopus 로고
    • Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer
    • Sargent DJ, Marsoni S, Monges G, Thibodeau SN, Labianca R, Hamilton SR, et al. Defective mismatch repair as a predictive marker for lack of efficacy of fluorouracil-based adjuvant therapy in colon cancer. J Clin Oncol 2010;28:3219-26.
    • (2010) J Clin Oncol , vol.28 , pp. 3219-3226
    • Sargent, D.J.1    Marsoni, S.2    Monges, G.3    Thibodeau, S.N.4    Labianca, R.5    Hamilton, S.R.6
  • 43
    • 84984879041 scopus 로고    scopus 로고
    • Prognostic value of CpG island methylator phenotype among colorectal cancer patients: A systematic review and meta-analysis
    • Juo YY, Johnston FM, Zhang DY, Juo HH, Wang H, Pappou EP, et al. Prognostic value of CpG island methylator phenotype among colorectal cancer patients: a systematic review and meta-analysis. Ann Oncol 2014;25:2314-27.
    • (2014) Ann Oncol , vol.25 , pp. 2314-2327
    • Juo, Y.Y.1    Johnston, F.M.2    Zhang, D.Y.3    Juo, H.H.4    Wang, H.5    Pappou, E.P.6
  • 44
    • 84867298938 scopus 로고    scopus 로고
    • The prognostic value of BRAF mutation in colorectal cancer and melanoma: A systematic review and meta-analysis
    • Safaee Ardekani G, Jafarnejad SM, Tan L, Saeedi A, Li G. The prognostic value of BRAF mutation in colorectal cancer and melanoma: a systematic review and meta-analysis. PLoS One 2012;7:e47054.
    • (2012) PLoS One , vol.7
    • Safaee Ardekani, G.1    Jafarnejad, S.M.2    Tan, L.3    Saeedi, A.4    Li, G.5
  • 45
    • 78649473910 scopus 로고    scopus 로고
    • The BRAF v600e mutation is an independent prognostic factor for survival in stage ii and stage iii colon cancer patients
    • Farina-Sarasqueta A, van Lijnschoten G, Moerland E, Creemers GJ, Lemmens VE, Rutten HJ, et al. The BRAF v600e mutation is an independent prognostic factor for survival in stage ii and stage iii colon cancer patients. Ann Oncol 2010;21:2396-402.
    • (2010) Ann Oncol , vol.21 , pp. 2396-2402
    • Farina-Sarasqueta, A.1    Van Lijnschoten, G.2    Moerland, E.3    Creemers, G.J.4    Lemmens, V.E.5    Rutten, H.J.6
  • 46
    • 84881640407 scopus 로고    scopus 로고
    • Microsatellite instability and BRAF mutation testing in colorectal cancer prognostication
    • Lochhead P, Kuchiba A, Imamura Y, Liao X, Yamauchi M, Nishihara R, et al. Microsatellite instability and BRAF mutation testing in colorectal cancer prognostication. J Natl Cancer Inst 2013;105:1151-6.
    • (2013) J Natl Cancer Inst , vol.105 , pp. 1151-1156
    • Lochhead, P.1    Kuchiba, A.2    Imamura, Y.3    Liao, X.4    Yamauchi, M.5    Nishihara, R.6
  • 47
    • 84856512550 scopus 로고    scopus 로고
    • Predictive and prognostic roles of BRAF mutation in stage III colon cancer: Results from intergroup trial CALGB 89803
    • Ogino S, Shima K, Meyerhardt JA, McCleary NJ, Ng K, Hollis D, et al. Predictive and prognostic roles of BRAF mutation in stage III colon cancer: results from intergroup trial CALGB 89803. Clin Cancer Res 2012;18:890-900.
    • (2012) Clin Cancer Res , vol.18 , pp. 890-900
    • Ogino, S.1    Shima, K.2    Meyerhardt, J.A.3    McCleary, N.J.4    Ng, K.5    Hollis, D.6
  • 49
    • 22244472992 scopus 로고    scopus 로고
    • Poor survival associated with the BRAF v600e mutation in microsatellite-stable colon cancers
    • Samowitz WS, Sweeney C, Herrick J, Albertsen H, Levin TR, Murtaugh MA, et al. Poor survival associated with the BRAF v600e mutation in microsatellite-stable colon cancers. Cancer Res 2005;65:6063-9.
    • (2005) Cancer Res , vol.65 , pp. 6063-6069
    • Samowitz, W.S.1    Sweeney, C.2    Herrick, J.3    Albertsen, H.4    Levin, T.R.5    Murtaugh, M.A.6
  • 50
    • 84907020986 scopus 로고    scopus 로고
    • Comparison of CpG island methylator phenotype (CIMP) frequency in colon cancer using different probe- and gene-specific scoring alternatives on recommended multi-gene panels
    • Berg M, Hagland HR, Soreide K. Comparison of CpG island methylator phenotype (CIMP) frequency in colon cancer using different probe- and gene-specific scoring alternatives on recommended multi-gene panels. PLoS One 2014;9:e86657.
    • (2014) PLoS One , vol.9
    • Berg, M.1    Hagland, H.R.2    Soreide, K.3
  • 51
    • 0033135049 scopus 로고    scopus 로고
    • Methylation of CpG in a small region of the HMLH1 promoter invariably correlates with the absence of gene expression
    • Deng G, Chen A, Hong J, Chae HS, Kim YS. Methylation of CpG in a small region of the HMLH1 promoter invariably correlates with the absence of gene expression. Cancer Res 1999;59:2029-33.
    • (1999) Cancer Res , vol.59 , pp. 2029-2033
    • Deng, G.1    Chen, A.2    Hong, J.3    Chae, H.S.4    Kim, Y.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.