Subsets of microsatellite-unstable colorectal cancers exhibit discordance between the CpG island methylator phenotype and MLH1 methylation status

Modern Pathology

Volumn 26, Issue 7, 2013, Pages 1013-1022

  Kim, Jung H ^a   Rhee, Ye Y ^a   Bae, Jeong M ^a   Kwon, Hyeong J ^a   Cho, Nam Y ^a   Kim, Mi J ^b   Kang, Gyeong H ^a  

^a Seoul National University College of Medicine   (South Korea)

^b Asan Medical Center   (South Korea)

Author keywords

colorectal cancer; CpG island; CpG island methylator phenotype; DNA methylation; MLH1

Indexed keywords

K RAS PROTEIN; PROTEIN MLH1; PROTEIN MSH2; MLH1 PROTEIN, HUMAN; NUCLEAR PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ADULT; ARTICLE; CANCER INCIDENCE; CANCER STAGING; COLORECTAL CANCER; CONTROLLED STUDY; CPG ISLAND; CPG ISLAND METHYLATOR PHENOTYPE; FEMALE; GENE MUTATION; HUMAN; MAJOR CLINICAL STUDY; MALE; METHYLATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR VOLUME; AGED; COLORECTAL TUMOR; DNA METHYLATION; GENETICS; IMMUNOHISTOCHEMISTRY; MICROSATELLITE INSTABILITY; MIDDLE AGED; PATHOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AGED; COLORECTAL NEOPLASMS; CPG ISLANDS; DNA METHYLATION; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICROSATELLITE INSTABILITY; MIDDLE AGED; NUCLEAR PROTEINS; PHENOTYPE;

EID: 84879946650     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2012.241     Document Type: Article

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