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European Journal of Medicinal Chemistry

Volumn 110, Issue , 2016, Pages 65-75

Novel dihydropyrazole-chromen: Design and modulates hTERT inhibition proliferation of MGC-803

(6) Chen, Yan Yan a Wu, Xiao Qin a Tang, Wen Jian a Shi, Jing Bo a Li, Jun a Liu, Xin Hua a

a ANHUI MEDICAL UNIVERSITY (China)

Author keywords

Dihydropyrazole chromen; Selective anticancer activity; Telomerase; TERT modulator

Indexed keywords

3 [3 PHENYL 1 [2 (PIPERIDIN 1 YL)ACETYL] 4,5 DIHYDRO 1H PYRAZOL 5 YL] 2H CHROMEN 2 ONE; ANTINEOPLASTIC AGENT; BETA CATENIN; CHROMENE DERIVATIVE; CYCLIN D1; FLUOROURACIL; MYC PROTEIN; PYRAZOLE DERIVATIVE; TELOMERASE REVERSE TRANSCRIPTASE; UNCLASSIFIED DRUG; BENZOPYRAN DERIVATIVE; TELOMERASE; TERT PROTEIN, HUMAN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER CELL LINE; CELL PROLIFERATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG STRUCTURE; ENZYME INHIBITION; G1 PHASE CELL CYCLE CHECKPOINT; GASTRIC CANCER CELL LINE; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; PROSTATE CANCER CELL LINE; SIGNAL TRANSDUCTION; ANTAGONISTS AND INHIBITORS; CELL CYCLE; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR MODEL; NEOPLASMS; PATHOLOGY; TUMOR CELL LINE; X RAY CRYSTALLOGRAPHY;

ANTINEOPLASTIC AGENTS; BENZOPYRANS; BETA CATENIN; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CRYSTALLOGRAPHY, X-RAY; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MODELS, MOLECULAR; NEOPLASMS; PROTO-ONCOGENE PROTEINS C-MYC; PYRAZOLES; TELOMERASE;

EID: 84955282336 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2016.01.014 Document Type: Article

Times cited : (22)

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