Isothiazolone derivatives selectively inhibit telomerase from human and rat cancer cells in vitro

Biochemistry

Volumn 38, Issue 35, 1999, Pages 11501-11507

  Hayakawa, Nobuki ^a   Nozawa, Katsura ^c   Ogawa, Akio ^b   Kato, Naoki ^b   Yoshida, Kenji ^b   Akamatsu, Ken Ichi ^b   Tsuchiya, Masayuki ^b   Nagasaka, Akio ^a   Yoshida, Shonen ^c  

^a FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^c NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 [3 (TRIFLUOROMETHYL)PHENYL]ISOTHIAZOLIN 3 ONE; DNA POLYMERASE; ISOTHIAZOLE DERIVATIVE; RNA DIRECTED DNA POLYMERASE; TELOMERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CARCINOGENESIS; DRUG POTENCY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTINEOPLASTIC AGENTS; DITHIOTHREITOL; DNA POLYMERASE BETA; DNA POLYMERASE I; ENZYME INHIBITORS; GLUTATHIONE; HIV-1 REVERSE TRANSCRIPTASE; HL-60 CELLS; HUMANS; MALE; RATS; RATS, INBRED STRAINS; SULFHYDRYL REAGENTS; TELOMERASE; THIAZOLES; TUMOR CELLS, CULTURED;

ANIMALIA; EUKARYOTA; HUMAN IMMUNODEFICIENCY VIRUS;

EID: 0033621094     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi982829k     Document Type: Article

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