Promoter methylation of the Wnt/β-catenin signaling antagonist Dkk-3 is associated with poor survival in gastric cancer

Cancer

Volumn 115, Issue 1, 2009, Pages 49-60

  Yu, Jun ^a,e   Tao, Qian ^a   Cheng, Yuen Y ^a   Lee, Kwan Y ^a   Ng, Simon S M ^a   Cheung, Kin F ^a   Tian, Linwei ^a   Rha, Sun Y ^b   Neumann, Ulf ^c   Röcken, Christoph ^c   Ebert, Matthias P A ^d   Chan, Francis K L ^a   Sung, Joseph J Y ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b Yonsei University College of Medicine   (South Korea)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Dickkopf homolog 3; Digestive tumors; Methylation; Prognosis; Tumor suppressor gene

Indexed keywords

BETA CATENIN; DICKKOPF 3 PROTEIN; GLYCOPROTEIN; MESSENGER RNA; TRICHOSTATIN A; UNCLASSIFIED DRUG; WNT PROTEIN; DECITABINE;

ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER SURVIVAL; COLONY FORMATION; COLORECTAL CANCER; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; METHYLATION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN METHYLATION; SIGNAL TRANSDUCTION; STOMACH CANCER; AGED; CANCER CHEMOTHERAPY; CANCER INHIBITION; CANCER PROGNOSIS; CORRELATIONAL STUDY; DKK 3 GENE; DNA METHYLATION; EPIGENETICS; FEMALE; GENE; GENE EXPRESSION PROFILING; MAJOR CLINICAL STUDY; MALE; PROMOTER REGION; SURVIVAL RATE; TREATMENT OUTCOME;

BETA CATENIN; CELL LINE, TUMOR; CELL PROLIFERATION; COLORECTAL NEOPLASMS; DNA METHYLATION; DOWN-REGULATION; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; PROGNOSIS; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS; SURVIVAL ANALYSIS; WNT PROTEINS;

EID: 58949084494     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.23989     Document Type: Article

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