-
1
-
-
2942522762
-
The 12-month prevalence and trends in DSM-IV alcohol abuse and dependence: United States, 1991-1992 and 2001-2002
-
Grant, B. F. et al. The 12-month prevalence and trends in DSM-IV alcohol abuse and dependence: United States, 1991-1992 and 2001-2002. Drug and alcohol dependence 74, 223-234 (2004)
-
(2004)
Drug and Alcohol Dependence
, vol.74
, pp. 223-234
-
-
Grant, B.F.1
-
2
-
-
59249097875
-
Alcohol-use disorders
-
Schuckit, M. A. Alcohol-use disorders. Lancet 373, 492-501 (2009)
-
(2009)
Lancet
, vol.373
, pp. 492-501
-
-
Schuckit, M.A.1
-
4
-
-
2342615476
-
Genetic study of alcoholism and novel gene expression in the alcoholic brain
-
Fan, L., Bellinger, F., Ge, Y. L. & Wilce, P. Genetic study of alcoholism and novel gene expression in the alcoholic brain. Addiction biology 9, 11-18 (2004)
-
(2004)
Addiction Biology
, vol.9
, pp. 11-18
-
-
Fan, L.1
Bellinger, F.2
Ge, Y.L.3
Wilce, P.4
-
5
-
-
13844250333
-
DNA hypermethylation of the alpha synuclein promoter in patients with alcoholism
-
Bonsch, D., Lenz, B., Kornhuber, J. & Bleich, S. DNA hypermethylation of the alpha synuclein promoter in patients with alcoholism. Neuroreport 16, 167-170 (2005)
-
(2005)
Neuroreport
, vol.16
, pp. 167-170
-
-
Bonsch, D.1
Lenz, B.2
Kornhuber, J.3
Bleich, S.4
-
6
-
-
33747880446
-
Lowered DNA methyltransferase (DNMT-3b) mRNA expression is associated with genomic DNA hypermethylation in patients with chronic alcoholism
-
Bonsch, D. et al. Lowered DNA methyltransferase (DNMT-3b) mRNA expression is associated with genomic DNA hypermethylation in patients with chronic alcoholism. J Neural Transm 113, 1299-1304 (2006)
-
(2006)
J Neural Transm
, vol.113
, pp. 1299-1304
-
-
Bonsch, D.1
-
7
-
-
33645368048
-
Epigenetic DNA hypermethylation of the HERP gene promoter induces down-regulation of its mRNA expression in patients with alcohol dependence
-
Bleich, S. et al. Epigenetic DNA hypermethylation of the HERP gene promoter induces down-regulation of its mRNA expression in patients with alcohol dependence. Alcoholism, clinical and experimental research 30, 587-591 (2006)
-
(2006)
Alcoholism, Clinical and Experimental Research
, vol.30
, pp. 587-591
-
-
Bleich, S.1
-
8
-
-
46949093048
-
MAOA methylation is associated with nicotine and alcohol dependence in women
-
Philibert, R. A., Gunter, T. D., Beach, S. R., Brody, G. H. & Madan, A. MAOA methylation is associated with nicotine and alcohol dependence in women. American journal of medical genetics Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 147B, 565-570 (2008)
-
(2008)
American Journal of Medical Genetics Part B, Neuropsychiatric Genetics : The Official Publication of the International Society of Psychiatric Genetics 147B
, pp. 565-570
-
-
Philibert, R.A.1
Gunter, T.D.2
Beach, S.R.3
Brody, G.H.4
Madan, A.5
-
10
-
-
84867974078
-
Hypermethylation of OPRM1 promoter region in European Americans with alcohol dependence
-
Zhang, H. et al. Hypermethylation of OPRM1 promoter region in European Americans with alcohol dependence. J Hum Genet 57, 670-675 (2012)
-
(2012)
J Hum Genet
, vol.57
, pp. 670-675
-
-
Zhang, H.1
-
11
-
-
84872491357
-
Array-based profiling of DNA methylation changes associated with alcohol dependence
-
Zhang, H. et al. Array-based profiling of DNA methylation changes associated with alcohol dependence. Alcohol Clin Exp Res 37 Suppl 1, E108-115 (2013)
-
(2013)
Alcohol Clin Exp Res
, vol.37
, pp. E108-115
-
-
Zhang, H.1
-
12
-
-
84867399359
-
The impact of recent alcohol use on genome wide DNA methylation signatures
-
Philibert, R. A., Plume, J. M., Gibbons, F. X., Brody, G. H. & Beach, S. R. The impact of recent alcohol use on genome wide DNA methylation signatures. Front Genet 3, 54 (2012)
-
(2012)
Front Genet
, vol.3
, pp. 54
-
-
Philibert, R.A.1
Plume, J.M.2
Gibbons, F.X.3
Brody, G.H.4
Beach, S.R.5
-
13
-
-
84872500748
-
Ethanol-induced Htr3a promoter methylation changes in mouse blood and brain
-
Barker, J. M., Zhang, Y., Wang, F., Taylor, J. R. & Zhang, H. Ethanol-induced Htr3a promoter methylation changes in mouse blood and brain. Alcohol Clin Exp Res 37 Suppl 1, E101-107 (2013)
-
(2013)
Alcohol Clin Exp Res
, vol.37
, pp. E101-107
-
-
Barker, J.M.1
Zhang, Y.2
Wang, F.3
Taylor, J.R.4
Zhang, H.5
-
14
-
-
79953191540
-
Prodynorphin CpG-SNPs associated with alcohol dependence: Elevated methylation in the brain of human alcoholics
-
Taqi, M. M. et al. Prodynorphin CpG-SNPs associated with alcohol dependence: elevated methylation in the brain of human alcoholics. Addiction biology 16, 499-509 (2011)
-
(2011)
Addiction Biology
, vol.16
, pp. 499-509
-
-
Taqi, M.M.1
-
15
-
-
84858156849
-
Global DNA promoter methylation in frontal cortex of alcoholics and controls
-
Manzardo, A. M., Henkhaus, R. S. & Butler, M. G. Global DNA promoter methylation in frontal cortex of alcoholics and controls. Gene 498, 5-12 (2012)
-
(2012)
Gene
, vol.498
, pp. 5-12
-
-
Manzardo, A.M.1
Henkhaus, R.S.2
Butler, M.G.3
-
16
-
-
84856474843
-
N. A. Methylation: Implications of this epigenetic mechanism for cancer research
-
Shenker, N., Flanagan, J. M. & Intragenic D. N. A. methylation: implications of this epigenetic mechanism for cancer research. Br J Cancer 106, 248-253 (2012)
-
(2012)
Br J Cancer
, vol.106
, pp. 248-253
-
-
Shenker, N.1
Flanagan, J.M.2
Intragenic, D.3
-
17
-
-
84867145980
-
On the presence and role of human gene-body DNA methylation
-
Jjingo, D., Conley, A. B., Yi, S. V., Lunyak, V. V. & Jordan, I. K. On the presence and role of human gene-body DNA methylation. Oncotarget 3, 462-474 (2012)
-
(2012)
Oncotarget
, vol.3
, pp. 462-474
-
-
Jjingo, D.1
Conley, A.B.2
Yi, S.V.3
Lunyak, V.V.4
Jordan, I.K.5
-
18
-
-
84864089089
-
Conserved intergenic elements and DNA methylation cooperate to regulate transcription at the il17 locus
-
Thomas, R. M., Sai, H. & Wells, A. D. Conserved intergenic elements and DNA methylation cooperate to regulate transcription at the il17 locus. The Journal of biological chemistry 287, 25049-25059 (2012)
-
(2012)
The Journal of Biological Chemistry
, vol.287
, pp. 25049-25059
-
-
Thomas, R.M.1
Sai, H.2
Wells, A.D.3
-
19
-
-
84862826741
-
Identification of methylation-dependent regulatory elements for intergenic miRNAs in human H4 cells
-
Lee, K. H., Kim, H., Lee, B. J. & Park, K. Identification of methylation-dependent regulatory elements for intergenic miRNAs in human H4 cells. Biochemical and biophysical research communications 420, 391-396 (2012)
-
(2012)
Biochemical and Biophysical Research Communications
, vol.420
, pp. 391-396
-
-
Lee, K.H.1
Kim, H.2
Lee, B.J.3
Park, K.4
-
20
-
-
84880958291
-
Protein Phosphatases but not Reactive Oxygen Species Play Functional Role in Acute Amphetamine- Mediated Dopamine Release
-
Paszti-Gere, E. & Jakus, J. Protein Phosphatases but not Reactive Oxygen Species Play Functional Role in Acute Amphetamine- Mediated Dopamine Release. Cell biochemistry and biophysics 66, 831-841 (2013)
-
(2013)
Cell Biochemistry and Biophysics
, vol.66
, pp. 831-841
-
-
Paszti-Gere, E.1
Jakus, J.2
-
21
-
-
84862640021
-
Beyond the dopamine receptor: Regulation and roles of serine/ threonine protein phosphatases
-
Walaas, S. I., Hemmings, H. C., Jr., Greengard, P. & Nairn, A. C. Beyond the dopamine receptor: regulation and roles of serine/ threonine protein phosphatases. Frontiers in neuroanatomy 5, 50 (2011)
-
(2011)
Frontiers in Neuroanatomy
, vol.5
, pp. 50
-
-
Walaas, S.I.1
Hemmings, H.C.2
Greengard, P.3
Nairn, A.C.4
-
22
-
-
60549111634
-
WGCNA: An R package for weighted correlation network analysis
-
Langfelder, P. & Horvath, S. WGCNA: an R package for weighted correlation network analysis. BMC bioinformatics 9, 559 (2008)
-
(2008)
BMC Bioinformatics
, vol.9
, pp. 559
-
-
Langfelder, P.1
Horvath, S.2
-
23
-
-
41349115432
-
The DAVID Gene Functional Classification Tool: A novel biological module-centric algorithm to functionally analyze large gene lists
-
Huang, D. W. et al. The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists. Genome Biol 8, R183 (2007)
-
(2007)
Genome Biol
, vol.8
, pp. R183
-
-
Huang, D.W.1
-
24
-
-
84891153206
-
Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci
-
Gelernter, J. et al. Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci. Molecular psychiatry 19, 41-49 (2014)
-
(2014)
Molecular Psychiatry
, vol.19
, pp. 41-49
-
-
Gelernter, J.1
-
25
-
-
84901255316
-
Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene
-
Gelernter, J. et al. Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene. Molecular psychiatry 19, 717-723 (2014)
-
(2014)
Molecular Psychiatry
, vol.19
, pp. 717-723
-
-
Gelernter, J.1
-
26
-
-
84902198211
-
Genome-wide association study of opioid dependence: Multiple associations mapped to calcium and potassium pathways
-
Gelernter, J. et al. Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways. Biol Psychiatry 76, 66-74 (2014)
-
(2014)
Biol Psychiatry
, vol.76
, pp. 66-74
-
-
Gelernter, J.1
-
27
-
-
84923120221
-
Genome-wide association study of nicotine dependence in American populations: Identification of novel risk loci in both African-Americans and European-Americans
-
Gelernter, J. et al. Genome-wide association study of nicotine dependence in American populations: identification of novel risk loci in both African-Americans and European-Americans. Biol Psychiatry 77, 493-503 (2015)
-
(2015)
Biol Psychiatry
, vol.77
, pp. 493-503
-
-
Gelernter, J.1
-
28
-
-
80053384370
-
Schizophrenia psychiatric genome-wide association study, C. Genome-wide association study identifies five new schizophrenia loci
-
Schizophrenia Psychiatric Genome-Wide Association Study, C. Genome-wide association study identifies five new schizophrenia loci. Nature genetics 43, 969-976 (2011)
-
(2011)
Nature Genetics
, vol.43
, pp. 969-976
-
-
-
29
-
-
80053385384
-
Psychiatric G. C. B. D. W. G, Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4
-
Psychiatric, G. C. B. D. W. G. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nature genetics 43, 977-983 (2011)
-
(2011)
Nature Genetics
, vol.43
, pp. 977-983
-
-
-
30
-
-
77956178166
-
Meta-analysis of genome-wide association studies of attention-deficit/hyperactivity disorder
-
Neale, B. M., et al. Meta-analysis of genome-wide association studies of attention-deficit/hyperactivity disorder. Journal of the American Academy of Child and Adolescent Psychiatry 49, 884-897 (2010)
-
(2010)
Journal of the American Academy of Child and Adolescent Psychiatry
, vol.49
, pp. 884-897
-
-
Neale, B.M.1
-
31
-
-
84879892380
-
A mega-analysis of genome-wide association studies for major depressive disorder
-
Major Depressive Disorder Working Group of the Psychiatric, G. C. et al.
-
Major Depressive Disorder Working Group of the Psychiatric, G. C. et al. A mega-analysis of genome-wide association studies for major depressive disorder. Molecular psychiatry 18, 497-511 (2013)
-
(2013)
Molecular Psychiatry
, vol.18
, pp. 497-511
-
-
-
32
-
-
84876296688
-
Cross-Disorder Group of the Psychiatric Genomics, C. Identification of risk loci with shared effects on five major psychiatric disorders: A genome-wide analysis
-
Cross-Disorder Group of the Psychiatric Genomics, C. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet 381, 1371-1379 (2013)
-
(2013)
Lancet
, vol.381
, pp. 1371-1379
-
-
-
33
-
-
78349293844
-
The genetics of autism spectrum disorders and related neuropsychiatric disorders in childhood
-
Lichtenstein, P., Carlstrom, E., Rastam, M., Gillberg, C. & Anckarsater, H. The genetics of autism spectrum disorders and related neuropsychiatric disorders in childhood. The American journal of psychiatry 167, 1357-1363 (2010)
-
(2010)
The American Journal of Psychiatry
, vol.167
, pp. 1357-1363
-
-
Lichtenstein, P.1
Carlstrom, E.2
Rastam, M.3
Gillberg, C.4
Anckarsater, H.5
-
34
-
-
84883465830
-
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
-
Cross-Disorder Group of the Psychiatric Genomics, C. et al.
-
Cross-Disorder Group of the Psychiatric Genomics, C. et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet 45, 984-994 (2013)
-
(2013)
Nat Genet
, vol.45
, pp. 984-994
-
-
-
35
-
-
84919449221
-
Differentially co-expressed genes in postmortem prefrontal cortex of individuals with alcohol use disorders: Influence on alcohol metabolism-related pathways
-
Zhang, H. et al. Differentially co-expressed genes in postmortem prefrontal cortex of individuals with alcohol use disorders: influence on alcohol metabolism-related pathways. Human genetics 133, 1383-1394 (2014)
-
(2014)
Human Genetics
, vol.133
, pp. 1383-1394
-
-
Zhang, H.1
-
36
-
-
84894056067
-
Sex-biased methylome and transcriptome in human prefrontal cortex
-
Xu, H. et al. Sex-biased methylome and transcriptome in human prefrontal cortex. Human molecular genetics 23, 1260-1270 (2014)
-
(2014)
Human Molecular Genetics
, vol.23
, pp. 1260-1270
-
-
Xu, H.1
-
37
-
-
84863986133
-
Functions of DNA methylation: Islands, start sites, gene bodies and beyond
-
Jones, P. A. Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nat Rev Genet 13, 484-492 (2012)
-
(2012)
Nat Rev Genet
, vol.13
, pp. 484-492
-
-
Jones, P.A.1
-
38
-
-
84907424835
-
Identification of methylation quantitative trait loci (mQTLs) influencing promoter DNA methylation of alcohol dependence risk genes
-
Zhang, H. et al. Identification of methylation quantitative trait loci (mQTLs) influencing promoter DNA methylation of alcohol dependence risk genes. Human genetics 133, 1093-1104 (2014)
-
(2014)
Human Genetics
, vol.133
, pp. 1093-1104
-
-
Zhang, H.1
-
39
-
-
84879054507
-
Profiling of childhood adversity-associated DNA methylation changes in alcoholic patients and healthy controls
-
Zhang, H., Wang, F., Kranzler, H. R., Zhao, H. & Gelernter, J. Profiling of childhood adversity-associated DNA methylation changes in alcoholic patients and healthy controls. PLoS One 8, e65648 (2013)
-
(2013)
PLoS One
, vol.8
, pp. e65648
-
-
Zhang, H.1
Wang, F.2
Kranzler, H.R.3
Zhao, H.4
Gelernter, J.5
-
40
-
-
84912117315
-
GPA: A statistical approach to prioritizing GWAS results by integrating pleiotropy and annotation
-
Chung, D., Yang, C., Li, C., Gelernter, J. & Zhao, H. GPA: a statistical approach to prioritizing GWAS results by integrating pleiotropy and annotation. PLoS genetics 10, e1004787 (2014)
-
(2014)
PLoS Genetics
, vol.10
, pp. e1004787
-
-
Chung, D.1
Yang, C.2
Li, C.3
Gelernter, J.4
Zhao, H.5
-
41
-
-
33846345905
-
Chronic alcohol drinking alters neuronal dendritic spines in the brain reward center nucleus accumbens
-
Zhou, F. C. et al. Chronic alcohol drinking alters neuronal dendritic spines in the brain reward center nucleus accumbens. Brain research 1134, 148-161 (2007)
-
(2007)
Brain Research
, vol.1134
, pp. 148-161
-
-
Zhou, F.C.1
-
42
-
-
71749084889
-
The role of DNA methylation in the central nervous system and neuropsychiatric disorders
-
Feng, J. & Fan, G. The role of DNA methylation in the central nervous system and neuropsychiatric disorders. Int Rev Neurobiol 89, 67-84 (2009)
-
(2009)
Int Rev Neurobiol
, vol.89
, pp. 67-84
-
-
Feng, J.1
Fan, G.2
-
43
-
-
77954504873
-
Conserved role of intragenic DNA methylation in regulating alternative promoters
-
Maunakea, A. K. et al. Conserved role of intragenic DNA methylation in regulating alternative promoters. Nature 466, 253-257 (2010)
-
(2010)
Nature
, vol.466
, pp. 253-257
-
-
Maunakea, A.K.1
-
45
-
-
79958754527
-
Validation of a DNA methylation microarray for 450, 000 CpG sites in the human genome
-
Sandoval, J. et al. Validation of a DNA methylation microarray for 450, 000 CpG sites in the human genome. Epigenetics 6, 692-702 (2011)
-
(2011)
Epigenetics
, vol.6
, pp. 692-702
-
-
Sandoval, J.1
-
47
-
-
84872564830
-
A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data
-
Teschendorff, A. E. et al. A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data. Bioinformatics 29, 189-196 (2013)
-
(2013)
Bioinformatics
, vol.29
, pp. 189-196
-
-
Teschendorff, A.E.1
-
48
-
-
33845432928
-
Adjusting batch effects in microarray expression data using empirical Bayes methods
-
Johnson, W. E., Li, C. & Rabinovic, A. Adjusting batch effects in microarray expression data using empirical Bayes methods. Biostatistics 8, 118-127 (2007)
-
(2007)
Biostatistics
, vol.8
, pp. 118-127
-
-
Johnson, W.E.1
Li, C.2
Rabinovic, A.3
-
49
-
-
0036753290
-
DNA methylation: A profile of methods and applications
-
Fraga, M. F. & Esteller, M. DNA methylation: a profile of methods and applications. BioTechniques 33, 632, 634, 636-649 (2002)
-
(2002)
BioTechniques
, vol.33
, Issue.632-634
, pp. 636-649
-
-
Fraga, M.F.1
Esteller, M.2
-
51
-
-
36348942314
-
Gender specific differences in levels of DNA methylation at selected loci from human total blood: A tendency toward higher methylation levels in males
-
El-Maarri, O. et al. Gender specific differences in levels of DNA methylation at selected loci from human total blood: a tendency toward higher methylation levels in males. Human genetics 122, 505-514 (2007)
-
(2007)
Human Genetics
, vol.122
, pp. 505-514
-
-
El-Maarri, O.1
-
52
-
-
77956311283
-
A study of the influence of sex on genome wide methylation
-
Liu, J., Morgan, M., Hutchison, K. & Calhoun, V. D. A study of the influence of sex on genome wide methylation. PLoS One 5, e10028 (2010)
-
(2010)
PLoS One
, vol.5
, pp. e10028
-
-
Liu, J.1
Morgan, M.2
Hutchison, K.3
Calhoun, V.D.4
-
53
-
-
41449085571
-
Eigengene networks for studying the relationships between co-expression modules
-
Langfelder, P. & Horvath, S. Eigengene networks for studying the relationships between co-expression modules. BMC Syst Biol 1, 54 (2007)
-
(2007)
BMC Syst Biol
, vol.1
, pp. 54
-
-
Langfelder, P.1
Horvath, S.2
-
54
-
-
0038054341
-
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
Mootha, V. K. et al. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 34, 267-273 (2003)
-
(2003)
Nat Genet
, vol.34
, pp. 267-273
-
-
Mootha, V.K.1
-
55
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian, A. et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proceedings of the National Academy of Sciences of the United States of America 102, 15545-15550 (2005)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
-
56
-
-
77957914609
-
The psychiatric GWAS consortium: Big science comes to psychiatry
-
Sullivan, P. F. The psychiatric GWAS consortium: big science comes to psychiatry. Neuron 68, 182-186 (2010).
-
(2010)
Neuron
, vol.68
, pp. 182-186
-
-
Sullivan, P.F.1
|