Genome-wide association study of nicotine dependence in American populations: Identification of novel risk loci in both African-Americans and European-Americans

Biological Psychiatry

Volumn 77, Issue 5, 2015, Pages 493-503

  Gelernter, Joel ^a,b   Kranzler, Henry R ^c   Sherva, Richard ^d   Almasy, Laura ^e   Herman, Aryeh I ^a,b   Koesterer, Ryan ^d   Zhao, Hongyu ^f   Farrer, Lindsay A ^d  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH   (United States)

^f YALE UNIVERSITY   (United States)

Author keywords

AMPK pathway; DISC1; DLC1; eNOS pathway; FTND; GWAS; Nicotine dependence; Population differences

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; NICOTINE; NITRIC OXIDE SYNTHASE; SPACER DNA;

AFRICAN AMERICAN; ARTICLE; BASE PAIRING; CHRNA3 GENE; CHRNA5 GENE; CHRNB4 GENE; CHROMOSOME 15; CHROMOSOME 7; CHROMOSOME 8; CHROMOSOME MAP; DISC1 GENE; DLC1 GENE; EUROPEAN AMERICAN; FAGERSTROM TEST FOR NICOTINE DEPENDENCE; GENE; GENE CLUSTER; GENE LOCUS; GENETIC ASSOCIATION; OPIATE ADDICTION; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; TOBACCO DEPENDENCE; TSNAX GENE; CAUCASIAN; COMPARATIVE STUDY; GENETIC DATABASE; GENETIC PREDISPOSITION; GENETICS; GENOTYPING TECHNIQUE; HUMAN; META ANALYSIS; SEVERITY OF ILLNESS INDEX; UNITED STATES;

AFRICAN AMERICANS; DATABASES, GENETIC; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPING TECHNIQUES; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; SEVERITY OF ILLNESS INDEX; SMOKING; TOBACCO USE DISORDER; UNITED STATES;

EID: 84923120221     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2014.08.025     Document Type: Article

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