Activities of tannins-From in Vitro studies to clinical trials

Natural Product Communications

Volumn 10, Issue 11, 2015, Pages 1877-1884

  Sieniawska, Elwira ^a  

^a MEDICAL UNIVERSITY OF LUBLIN   (Poland)

Author keywords

Bioactivity in vitro; Bioactivity in vivo; Clinical trials; Tannins

Indexed keywords

1 DESGALLOYL RUGOSIN F; AGRIMONIIN; CASUARININ; CHEBULINIC ACID; CORIARIIN A; CRANBERRY EXTRACT; CRATAEGUS EXTRACT; ELLAGITANNIN; EPIACUTISSIMIN A; EPIACUTISSIMIN B; EUPHORBIN C; GERANIIN; GRANDININ; GREEN TEA EXTRACT; ISOTERCHEBIN; KAKI TANNIN; MALLOTUSINIC ACID; OENOTHEIN B; PEDUNCULAGIN; PENTAGALLOYL GLUCOSE; POLYPHENOL; PRAECOXIN; PROCYANIDIN DERIVATIVE; PYCNOGENOL; ROBURIN E; TANNIN DERIVATIVE; TELLIMAGRANDIN I; TELLIMAGRANDIN II; THEASINENSIN A; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIDIABETIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIOBESITY ACTIVITY; ANTIOXIDANT ACTIVITY; ANTIULCER ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CACAO; CELL PROTECTION; CRANBERRY; CYTOTOXICITY; DPPH RADICAL SCAVENGING ASSAY; DRUG ACTIVITY; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; HEART PROTECTION; HISTAMINE RELEASE; HUMAN; LIPID PEROXIDATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; OXIDATIVE STRESS; RANDOMIZED CONTROLLED TRIAL (TOPIC); TEA; WOUND HEALING; CHEMICAL STRUCTURE; CHEMISTRY; CLINICAL TRIAL (TOPIC); DRUG THERAPY;

CLINICAL TRIALS AS TOPIC; DRUG THERAPY; HUMANS; MOLECULAR STRUCTURE; TANNINS;

EID: 84955114650     PISSN: 1934578X     EISSN: 15559475     Source Type: Journal    
DOI: None     Document Type: Article

References (84)

1. Khanbabaee K, Van Ree T. (2001) Tannins: Classification and definition. Natural Products Reports, 18, 641-649.
2. He F, Pan QH, Shi Y, Duan ChQ. (2008) Biosynthesis and genetic regulation of proanthocyanidins in plants. Molecules, 13, 2674-2703.
3. De Bruyne T, Pieters L, Deelstra H, Vlietinck A. (1999) Condensed vegetable tannins: Biodiversity in structure and biological activities. Biochemical Systematics & Ecology, 27, 445-459.
4. Serrano J, Puupponen-Pimi R, Dauer A, Aura AM, Saura-Calixto F. (2009) Tannins: Current knowledge of food sources, intake, bioavailability and biological effects. Molecular Nutrition & Food Research, 53, 310-329.
5. Okuda T. (2005) Systematics and health effects of chemically distinct tannins in medicinal plants Phytochemistry, 66, 2012-2031.
6. Jerez M, Tourio S, Sineiro J, Torres JL, Nuez MJ. (2007) Procyanidins from pine bark: Relationships between structure, composition and antiradical activity. Food Chemistry, 104, 518-27.
7. Tian Y, Zou B, Li CM, Yang J, Xu SF, Hagerman AE. (2012) High molecular weight persimmon tannin is a potent antioxidant both ex vivo and in vivo. Food Research International, 45, 26-30.
8. Ariga T, Koshiyama I, Fukushima D. (1988) Antioxidative properties of procyanidins B-1 and B-3 from adzuki beans in aqueous system. Agricultural & Biological Chemistry, 52, 2717-2722.
9. Scalbert A. (1991) Antimicrobial properties of tannins. Phytochemistry, 30, 3875-3883.
10. Yilmaz Y. (2006) Novel uses of catechins in foods. Trends in Food Science & Technology, 17, 64-71.
11. Díaz-Gomez R, Toledo-Araya H, Lopez-Solís R, Obreque-Slier E. (2014) Combined effect of gallic acid and catechin against Escherichia coli. LWT-Food Science and Technology, 59, 896-900.
12. Díaz-Gomez R, Lopez-Solís R, Obreque-Slier E, Toledo-Araya H. (2013) Comparative antibacterial effect of gallic acid and catechin against Helicobacter pylori. LWT-Food Science and Technology, 54, 331-335.
13. Funatogawa K, Hayashi S, Shimomura H, Yoshida T, Hatano T, Ito H, Hiraii Y. (2004) Antibacterial activity of hydrolysable tannins derived from medicinal plants against Helicobacter pylori; Microbiology and Immunology, 48, 251-261.
14. Wu-Yuan CD, Chen CY, Wu RT. (1988) Gallotannins inhibit growth, water insoluble glucan synthesis, and aggregation of mutans streptococci. Journal of Dental Research, 67, 51-55.
15. Singh IP, Bharate SB, Bhutani KK. (2005) Anti-HIV natural products. Current Science, 89, 269-290.
16. Tzonuis X, Vulevic J, Kuhnle GG, George T, Leonczak J, Gibson GR, Kwik-Uribe C, Spencer JP. (2008) Flavanol monomer-induced changes to the human faecal microflora. British Journal of Nutrition, 99, 782-792.
17. Cardona F, Andrés-Lacuev C, Tulipani S, Tinahones FJ, Queipo-Ortuño MI. (2013) Benefits of polyphenols on gut microbiota and implications in human health. Journal of Nutritional Biochemistry, 24, 1415-1422.
18. Okuda T, Ito H. (2011) Tannins of constant structure in medicinal and food plants-hydrolysable tannins and polyphenols related to tannins. Molecules, 16, 2191-2217.
19. Hatano T, Kusuda M, Inada K, Ogawa T, Shiota S, Tsuchiya T, Yoshida T. (2005) Effects of tannins and related polyphenols on methicillinresistant Staphylococcus aureus. Phytochemistry, 66, 2047-2055.
20. Howell AB, Vorsa N, Der Marderosian A, Foo LY. (1998) Inhibition of the adherence of P-fimbriated Escherichia coli to uroepithelial-cell surfaces by proanthycyanidin extracts from cranberries. New England Journal of Medicine, 339, 1085-1086.
21. Howell AB, Leahy M, Kurowska E, Guthrie N. (2001) In vivo evidence that cranberry proanthocyanidins inhibit adherence of P-fimbriated E. coli bacteria to uroepithelial cells. FASEB Journal, 15, A284.
22. Fukuchi K, Sakagami H, Okuda T, Hatano T, Tanuma S, Kitajima K, Inoue Y, Inoue S, Ichikawa S, Nonoyama M, Konno K. (1989) Inhibition of herpes simplex virus infection by tannins and related compounds. Antiviral Research, 11, 285-297.
23. Takechi M, Tanaka Y, Takehara M, Nonaka GI, Nishioka I. (1985) Structure and antiherpetic activity among the tannins. Phytochemistry, 24, 2245-2250.
24. Ubillas R, Jolad SD, Bruening RC, Kernan MR, King SR, Sesin DF, Barrett M, Stoddart CA, Flaster T, Kuo J, Ayala F, Meza E, Castanel M, McMekkin D, Rozhon E, Tempesta MS, Barnard D, Huffman J, Smee D, Sidwell R, Soike K, Brazier A, Safrin S, Orlando R, Kenny PT, Berova N, Nakanishi K. (1994) SP-303 an antiviral oligomeric proantocyanidin from the latex of Croton lechleri (Sangre de Drago). Phytomedicine, 1, 77-106.
25. Cheng H, Lin C, Lin T. (2002) Antiherpes simplex virus type 2 activity of casuarinin from the bark of Terminalia arjuna Linn. Antiviral Research, 55, 447-455.
26. Lin LT, Chen TY, Lin SC, Chun CY, Lin TC, Wang GH, Anderson R, Lin CC, Richardson CD. (2013) Broad-spectrum antiviral activity of chebulagic acid and punicalagin against viruses that use glycosaminoglycans for entry. BMC Microbiology, 13, 187-202.
27. Ajala OS, JukovA, MaCM. (2014) Hepatitis C virus inhibitory hydrolysable tannins from the fruits of Terminalia chebula. Fitoterapia, 99, 117-123.
28. Kakiuchi N, Kusumoto I, Hattori M, Namba T, Hatano T, Okuda T. (1991) Effect of condensed tannins and related compounds on reverse transcriptase. Phytotherapy Research, 5, 270-272.
29. Jastrzebska M, Zalewska-Rejdak J, Wrzalik R, Kocot A, Mroz I, Barwinski B, Turek A, Cwalina B. (2006) Tannic acid-stabilized pericardium tissue: IR spectroscopy, atomic force microscopy, and dielectric spectroscopy investigations. Journal of Biomedical Materials Research, 78A, 148-156.
30. Isenburg JC, Simionescu DT, Vyavahare NR. (2004) Elastin stabilization In cardiovascular implants: improved resistance to enzymatic degradation by treatment with tannic acid. Biomaterials, 25, 3293-3302.
31. Isenburg JC, Simionescu DT, Vyavahare NR. (2005) Tannic acid treatment enhances biostability and reduces calcification of glutaraldehyde fixed aortic wall. Biomaterials, 25, 1237-1245.
32. Beretta G, Rossoni G, Santagati NA, Facino RM. (2009) Anti-ischemic activity and endothelium-dependent vasorelaxant effect of hydrolysable tannins from the leaves of Rhus coriaria (Sumac) in isolated rabbit heart and thoracic aorta. Planta Medica, 75, 1482-1488.
33. Xie YW, Xuc HX, Dongc H, Fiscus RR, But PPH. (2007) Role of nitric oxide in the vasorelaxant and hypotensive effects of extracts and purified tannins from Geum japonicum. Journal of Ethnopharmacology, 109, 128-133.
34. Flesch M, Schwarz A, Bohm M. (1998) Effects of red and white wine on endothelium-dependent vasorelaxation of rat aorta and human coronary arteries. American Journal of Physiology, 275, 1183-1190.
35. Lee H, Lee JY, Suh MH, Sim SS, Lee M, Kim CJ. (2010) Hydrolysable tannins depress cardiac papillary muscle contraction and propranololinduced negative inotropism. Fitoterapia, 81, 820-825.
36. Magos GA, Mateos JC, Páez E, Fernández G, Lobato C, Márquez C, Enriquez RG. (2008) Hypotensive and vasorelaxant effects of the procyanidin fraction from Guazuma ulmifolia bark in normotensive and hypertensive rats. Journal of Ethnopharmacology, 117, 58-68.
37. Karthikeyan K, Bai BR, Devaraj SN. (2007) Cardioprotective effect of grape seed proanthocyanidins on isoproterenol-induced myocardial injury in rats. International Journal of Cardiology, 115, 326-333.
38. Russell JA, Rohrbach MS. (1989) Tannin induces endothelium-dependent contraction and relaxation of rabbit pulmonary artery. American Review of Respiratory Disease, 139, 498-503.
39. Kanohl R, Hatano T, Ito H, Yoshida T, AkagiM. (2000) Effects of tannins and related polyphenols on superoxide-induced histamine release from rat peritoneal mast cells. Phytomedicine, 7, 297-302.
40. Actis-Goretta L, Romanczyk LJ, Rodriguez CA, Kwik-Uribe C, Keen CL. (2008) Cytotoxic effects of digalloyl dimer procyanidins in human cancer cell lines. Journal of Nutritional Biochemistry, 19, 797-808.
41. Gadkaria PV, Balaraman M. (2015) Catechins: Sources, extraction and encapsulation.Food and Bioproducts Processing, 93, 122-138.
42. Tong WY, Wang H, Waisundara VY. (2014) Huang D. Inhibiting enzymatic starch digestion by hydrolysable tannins isolated from Eugenia jambolana; LWT-Food Science and Technology, 59, 389-395.
43. Miao M, Jiang H, Jiang B, Li Y, Cui SW, Zhang T. (2014) Structure elucidation of catechins for modulation of starch digestion. LWT-Food Science and Technology, 57, 188-193.
44. Kandra L, Gyemant G, Zajacz A, Batta G. (2004) Inhibitory effects of tannin on human salivary α-amylase. Biochemical and Biophysical Research Communications, 319, 1265-1271.
45. Matsui T, Ueda T, Oki T, Sugita K, Terahara N, Matsumoto K. (2001) Alpha-glucosidase inhibitory action of natural acylated anthocyanidins. Survey of natural pigments with potent inhibitory activity. Journal of Agricultural and Food Chemistry, 49, 1948-1951.
46. McDougall GJ, Shpiro F, Dobson P, Smith P, Blake A, Stewart D. (2005) Different polyphenolic components of soft fruits inhibit α-amylase and α-glucosidase. Journal of Agricultural and Food Chemistry, 53, 2760-2766.
47. Pinent M, Blay M, Blade MC, Salvado, MJ, Arola L, Ardevol A. (2004) Grape seed-derived procyanidins have an antihyperglycemic effect in streptozotocin-induced diabetic rats and insulinomimetic activity in insulin-sensitive cell lines. Endocrinology, 145, 4985-4990.
48. Moon HS, Chung CS, Lee HG, Kim TG, Choi YJ, Cho CS. (2007) Inhibitory effect of (-)-epigallocatechin-3-gallate on lipid accumulation of 3 T3-L1 cells. Obesity, 15, 2571-2582.
49. Hung PF, Wu BT, Chen HC, Chen YH, Chen CL, Wu MH. (2005) Antimitogenic effect of green tea (-)-epigallocatechin gallate on 3 T3-L1 preadipocytes depends on the ERK and Cdk2 pathways. American Journal of Physiology-Cell Physiology, 288, 1094-1108.
50. Chan CY, Wei L, Castro-Munozledo F, Koo WL. (2011) (-)-Epigallocatechin-3-gallate blocks 3T3-L1 adipose conversion by inhibition of cell proliferation and suppression of adipose phenotype expression. Life Science, 89, 779-785.
51. Wu BT, Hung PF, Chen HC, Huang RN, Chang HH, Kao YH. (2005) The apoptotic effect of green tea (-)-epigallocatechin gallate on 3 T3-L1 preadipocytes depends on the Cdk2 pathway. Journal of Agricultural and Food Chemistry, 53, 5695-5701.
52. Lin J, Della-Fera MA, Baile CA. (2005) Green tea polyphenol epigallocatechin gallate inhibits adipogenesis and induces apoptosis in 3 T3-L1 adipocytes. Obesity Research, 13, 982-990.
53. Wang S, Moustaid-Moussa N, Chen L, Mo H, Shastri A, Su R, Bapat P, Kwun I, Shen CL. (2014) Novel insights of dietary polyphenols and obesity. Journal of Nutritional Biochemistry, 25, 1-18.
54. Li Y, Kim J, Li J, Liu F, Liu X, Himmeldirk K, Ren Y, Wagner TE, Chen X. (2005) Natural anti-diabetic compound 1, 2, 3, 4, 6-penta-O-galloyl-Dglucopyranose binds to insulin receptor and activates insulin-mediated glucose transport signaling pathway.Biochemical and Biophysical Research Communications, 336, 430-437.
55. Agyare C, Lechtenberg M, Deters A, Petereit F, Hensel A. (2011) Ellagitannins from Phyllanthus muellerianus (Kuntze) Exell.:geraniin and furosin stimulate cellular activity, differentiation and collagen synthesis of human skin keratinocytes and dermal fibroblasts. Phytomedicine, 18, 617-624.
56. Wang R, Lechtenberg M, Sendker J, Petereit F, Deters A, Hensel A. (2013) Wound healing plants from TCM: in vitro investigations on selected TCM plants and their influence on human dermal fibroblasts and keratinocytes. Fitoterapia, 84, 308-317.
57. Singh D, Choi SM, Zo SM, Painuli RM, Kwon SW, Han SS. (2014) Effect of extracts of Terminalia chebula on proliferation of keratinocytes and fibroblasts cells: an alternative approach for wound healing. Evidenced Based and Complementary and Alternative Medicine, 2014; ID701656.
58. Piwowarski JP, Kiss AK, Kozłowska-Wojciechowska M. (2011) Anti-hyaluronidase and anti-elastase activity screening of tannin-rich plant materials used in traditional Polish medicine for external treatment of diseases with inflammatory background. Journal of Ethnopharmacology, 137, 937-941.
59. Zhang H, Zhu SJ, Wang D, Wei YJ, Hu SS. (2009) Intra myocardial injection of tannic acid attenuates postinfarction remodeling: a novel approach to stabilize the breaking extracellular matrix. Journal of Thoracic and Cardiovascular Surgery, 137, 216-222.
60. Vasconcelos PCP, Andreo MA, Vilegas W, Hiruma-Lima CA, Pellizzon CH. (2010) Effect of Mouriri pusa tannins and flavonoids on prevention and treatment against experimental gastric ulcer. Journal of Ethnopharmacology, 131, 146-153.
61. Chandranayagam Ch, Veeraraghavan G, Subash A, Vasanthi HR. (2013) Restoration of arsenite induced hepato-toxicity by crude tannin rich fraction of Theobroma cacao in Sprague Dawley rats. Food Research International, 50, 46-54.
62. Abbe MJ, Amin I, Chong P, Muhajir H, Hasbullah SK. (2008) Effects of cocoa extract on glucometabolism, oxidative stress, and antioxidant enzymes in obese-diabetic (ob-db) rats. Journal of Agricultural and Food Chemistry, 56, 7877-7884.
63. Saravanan G, Leelavinothan P. (2006) Effects of Syzygium cumini bark on blood glucose, plasma insulin and C-peptide in streptozotocin induced diabetic rats. International Journal of Endocrinology and Metabolism, 4, 96-105.
64. Matsumoto K, Yokoyama S. (2012) Induction of uncoupling protein-1 and-3 in brown adipose tissue by kaki-tannin in type 2 diabetic NSY/Hos mice. Food and Chemical Toxicology, 50, 184-190.
65. Wang Z, Guo QY, Zhang XJ, Li X, Li WT, Ma XT, Ma LJ. (2014) Corilagin attenuates aerosol bleomycin-induced experimental lung injury International Journal of Molecular Sciences, 15, 9762-9779.
66. Xiong Z, Yu QN, Zou ZB, He ZH, Zhang SJ, Xu RC, Yang M. (2014) Protective effects of tannins in Sanguisorbae radix on myelosuppression mice. Chinese Herbal Medicines, 6, 222-227.
67. Alexopoulos N, Vlachopoulos C, Aznaouridis K, Baou K, Vasiliadou C, Pietri P, Xaplanteris P, Stefanadi E, Stefanadis C. (2008) The acute effect of green tea consumption on endothelial function in healthy individuals. European Journal of Cardiovascular Prevention & Rehabilitation, 15, 300-305.
68. Maki KC, Reeves MS, Farmer M, Yasunaga K, Matsuo N, Katsuragi Y, Komikado M, Tokimitsu I, Wilder D, Jones F, Blumberg JB, Cartwright Y. (2009) Green tea catechin consumption enhances exercise-induced abdominal fat loss in overweight and obese adults. Journal of Nutrition, 139, 264-270.
69. Fukino Y, Ikeda A, Maruyama K, Aoki N, Okubo T, Iso H. (2008) Randomized controlled trial for an effect of green tea-extract powder supplementation on glucose abnormalities. European Journal of Clinical Nutrition, 62, 953-960.
70. Basu A, Du M, Sanchez K, Leyva MJ, Betts NM, Blevins S, Wu M, Aston CE, Lyons TJ. (2011) Green tea minimally affects biomarkers of inflammation in obese subjects with metabolic syndrome. Nutrition, 27, 206-213.
71. Diepvens K, Kovacs EM, Nijs IM, Vogels N, Westerterp-Plantenga MS. (2005) Effect of green tea on resting energy expenditure and substrate oxidation during weight loss in overweight females. British Journal of Nutrition, 94, 1026-1034.
72. Hill AM, Coates AM, Buckley JD, Ross R, Thielecke F, Howe PR. (2007) Can EGCG reduce abdominal fat in obese subjects? Journal of the American College of Nutrition, 26, 396-402.
73. Matsuyama T, Tanaka Y, Kamimaki I, Nagao T, Tokimitsu I. (2008) Catechin safely improved higher levels of fatness, blood pressure, and cholesterol in children. Obesity, 16, 1338-1348.
74. Sivaprakasapillai B, Edirisinghe I, Randolph J, Steinberg F, Kappagoda T. (2009) Effect of grape seed extract on blood pressure in subjects with the metabolic syndrome. Metabolism, 58, 1743-1746.
75. Zern TL, Wood RJ, Greene C, West KL, Liu Y, Aggarwal D, Shachter NS, Fernandrz ML. (2005) Grape polyphenols exert a cardioprotective effect in pre-and postmenopausal women by lowering plasma lipids and reducing oxidative stress. Journal of Nutrition, 135, 1911-1917.
76. Campia U, Panza JA. (2008) Flavanol-rich cocoa a promising new dietary intervention to reduce cardiovascular risk in type 2 diabetes? Journal of the American College of Cardiology, 51, 2150-2152.
77. Heiss C, Jahn S, Taylor M, Real WM, Angeli FS, Wong ML, Amabile N, Prasad M, Rassaf T, Ottaviani JI, Mihardja S, Keen CL, Springer ML, Boyle A., Grossman W, Glantz SA, Schroeter H, Yeghiazarians Y. (2010) Improvement of endothelial function with dietary flavanols in associated with mobilization of circulating angiogenic cells in patients with coronary artery disease. Journal of the American College of Cardiology, 56, 218-224.
78. Ried K, Sullivan TR, Fakler P, Frank OR, Stocks NP. (2012) Effect of cocoa on blood pressure. Cochrane Database Systemic Reviews, DOI: 10.1002/14651858.CD008893.pub2.
79. Jia L, Liu X, Bai YY, Li SH, Sun K, He C, Hui R. (2010) Short-term effect of cocoa product consumption on lipid profile: a meta-analysis of randomized controlled trials. American Journal of Clinical Nutrition, 92, 218-225.
80. Jepson RG, Williams G, Craig JC. (2012) Cranberries for preventing urinary tract infections Cochrane Database Systemic Reviews, DOI: 10.1002/14651858.CD001321.pub5.
81. Barbosa-Cesnik C, Brown MB, Buxton M, Zhang L, DeBusscher J, Foxman B. (2011) Cranberry juice fails to prevent recurrent urinary tract infection: results from a randomized placebo-controlled trial. Clinical Infection Diseases, 52, 23-30.
82. Guo R, PittlerMH, Ernst E. (2008) Hawthorn extract for treating chronic heart failure. Cochrane Database Systemic Reviews, DOI: 10.1002/14651858.CD005312.pub2.
83. D'Andrea G. (2010) Pycnogenol: A blend of procyanidins with multifaceted therapeutic applications? Fitoterapia, 81, 724-736.
84. Schoonees A, Visser J, Musekiwa A, Volmink J. (2011) Pycnogenol® (extract of French maritime pine bark) for the treatment of chronic disorders. Cochrane Database Systemic Reviews, DOI: 10.1002/14651858.CD008294.pub4.