Restoration of arsenite induced hepato-toxicity by crude tannin rich fraction of Theobroma cacao in Sprague Dawley rats

Food Research International

Volumn 50, Issue 1, 2013, Pages 46-54

  Chandranayagam, Chandronitha ^a   Veeraraghavan, Gayathri ^a   Subash, Ananthi ^a   Vasanthi, Hannah Rachel ^a,b  

^a SRI RAMACHANDRA UNIVERSITY   (India)

^b PONDICHERRY UNIVERSITY   (India)

Author keywords

Arsenic; Arsenic biomarker; Cellular thiol levels; Hepatotoxicity; Oxidative damage markers; Oxidative stress; Theobroma cacao

Indexed keywords

ADVERSE EFFECT; ARSENIC TOXICITY; CELLULAR THIOLS; FEMALE RAT; FUNCTIONAL FOODS; GLUTATHIONE PEROXIDASE; HEPATOTOXICITY; OXIDATIVE DAMAGE; PROTECTIVE EFFICACY; REDUCED GLUTATHIONE; SPRAGUE-DAWLEY RATS; SULFHYDRYL; SULFHYDRYL CONTENT; SUPEROXIDE DISMUTASES; THEOBROMA CACAO; THIOBARBITURIC ACID REACTIVE SUBSTANCES; TREATMENT GROUP;

ARSENIC; BIOMARKERS; CELL DEATH; COCOA; FLAVONOIDS; OXIDATIVE STRESS; OXYGEN; PEPTIDES; RATS; SODIUM; TOXICITY;

CHEMICAL CONTAMINATION;

RATTUS; THEOBROMA CACAO;

EID: 84868238652     PISSN: 09639969     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.foodres.2012.09.021     Document Type: Article

References (59)

1. Abbe M.J., Amin I., Chong P.P., Muhajir H., Hasbullah S.K. Effects of cocoa extract on glucometabolism, oxidative stress, and antioxidant enzymes in obesediabetic (ob-db) rats. Journal of Agriculture and Food Chemistry 2008, 56:7877-7884.
2. Amin I., Faizul H.A., Azl R. Effect of cocoa powder extract on plasma glucose levels in hyperglycaemic rats. Nutritional Food Science 2004, 34:116-121.
3. Amin I., Koh B.K., Asmah R. Effect of cacao liquor extract on tumor marker enzymes during chemical hepatocarcinogenesis in rats. Journal of Medicinal Food 2004, 7:7-12.
4. Arlorio M., Bottini C., Travaglia F., Locatelli M., Bordiga M., Coisson J.D., et al. Protective activity of Theobroma cacao L. phenolic extract on AML12 and MLP29 liver cells by preventing apoptosis and inducing autophagy. Journal of Agricultural and Food Chemistry 2009, 57:10612-10618.
5. 2. Food Research International 2005, 38:1009-1014.
6. Bera A.K., Rana T., Das S., Bandyopadhyay S., Bhattacharya D., Pan D., et al. l-Ascorbate protects rat hepatocytes against sodium arsenite-induced cytotoxicity and oxidative damage. Human and Experimental Toxicology 2010, 29(2):103-111.
7. Berlin A., Schaller K.H. European standardized method for the determination of delta aminolevulinic acid dehydratase activity in blood. Zeitschrift für Klinische Chemie und Klinische Biochemie 1974, 12:389-390.
8. Beyersmann D., Hartwig A. Carcinogenic metal compounds: Recent insight into molecular and cellular mechanisms. Archives of Toxicology 2008, 82:493-512.
9. Bhadauria S., Flora S.J.S. Arsenic induced inhibition of d-aminolevulinic acid dehydratase activity in rat blood and its response to meso 2,3-dimercapto-succinic acid and monoisoamyl DMSA. Biomedical and Environmental Sciences 2003, 17:305-313.
10. Borchers A.T., Keen C.L., Hannum S.M., Gershwin M.E. Cocoa and chocolate: Composition, bioavailability, and health implications. Journal of Medicinal Food 2000, 3:77-105.
11. Bryan N.S., Fernandez B.O., Bauer S.M., Garcia-Saura M.F., Milsom A.B., Rassaf T., et al. Nitrite is a signaling molecule and regulator of gene expression in mammalian tissues. Nature Chemical Biology 2005, 1(5):290-297.
12. Chandronitha C., Ananthi S., Ramakrishnan G., Lakshmisundaram R., Gayathri V., Vasanthi H.R. Protective role of tannin-rich fraction of Camellia sinensis in tissue arsenic burden in Sprague Dawley rats. Human and Experimental Toxicology 2010, 29(9):705-719.
13. Cooper K.A., Donovan J.L., Waterhouse A.L., Williamson G. Cocoa and health: A decade of research. British Journal of Nutrition 2008, 95:1016-1023.
14. Cosby K., Partovi K.S., Crawford J.H., Patel R.P., Reiter C.D., Martyr S., et al. Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation. Nature Medicine 2003, 9:1498-1505.
15. Datta S., Saha D.R., Ghosh R., Majumdar T., Bhattacharya S., Mazumder S. Sublethal concentration of arsenic interferes with the proliferation of hepatocytes and induces in vivo apoptosis in Clarias batrachus L. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 2007, 145:339-349.
16. Dopp E., von Recklinghausen U., Diaz-Bone R., Hirner A.V., Rettenmeier A.W. Cellular uptake, subcellular distribution and toxicity of arsenic compounds in methylating and nonmethylating cells. Environmental Research 2010, 110(5):435-442.
17. Ellman G.L. Tissue sulfhydryl groups. Archives of Biochemistry 1959, 82:70-77.
18. Flora S.J.S., Bhadauria S., Kannan G.M., Singh N. Arsenic induced oxidative stress and the role of antioxidant supplementation during chelation: A review. Journal of Environmental Biology 2007, 28(2):333-347.
19. Flora S.J.S., Mehta A., Rao P.V.L., Kannan G.M., Bhaokar A., Dube S.N., et al. Therapeutic potential of monoisoamyl and monomethyl esters of meso 2,3-dimercaptosuccimic acid in gallium arsenide intoxicated rats. Toxicology 2004, 195:127-146.
20. Gladwin M.T., Schechter A.N., Kim-Shapiro D.B., Patel R.P., Hogg N., Shiva S., et al. The emerging biology of the nitrite anion. Nature Chemical Biology 2005, 1(6):308-314.
21. Goel G., Puniya A.K., Aguliar C.N., Singh K. Interaction of gut microflora with tannins in feeds. Naturwissenschaften 2005, 92:497-503.
22. Green L.C., Wagner D.A., Glogowski J., Skipper P.L., Wishnok J.S., Tannenbaum S.R. Analysis of nitrate and nitrite in biological fluids. Annals of Biochemistry 1982, 126:131.
23. Gupta R., Flora S.J.S. Protective effects of fruit extracts of Hippophae rhamnoides L. against arsenic toxicity in Swiss albino mice. Human and Experimental Toxicology 2006, 25:285.
24. Gupta R., Flora S.J.S. Effect of Centella asiatica on arsenic induced oxidative stress and metal distribution in rats. Journal of Applied Toxicology 2006, 26:213-222.
25. Hord N.G., Tang Y., Bryan N.S. Food sources of nitrates and nitrites: The physiologic context for potential health benefits. American Journal of Clinical Nutrition 2009, 90(1):1-10.
26. Jain A., Yadav A., Bozhkov A.I., Padalko V.I., Flora S.J.S. Therapeutic efficacy of silymarin and naringenin in reducing arsenic-induced hepatic damage in young rats. Ecotoxicology and Environmental Safety 2011, 74(4):607-614.
27. Kakkar P., Das B., Viswanathan P.N. A modified spectrophotometric assay of superoxide dismutase. Indian Journal of Biochemistry & Biophysics 1984, 21:130-132.
28. Kapaj S., Peterson H., Liber K., Bhattacharya P. Human health effects from chronic arsenic poisoning-A review. Journal of Environmental Science and Health, Part A 2006, 41:2399-2428.
29. Keen C.K., Holt R.R., Oteiza P.I., Fraga C.G., Schmitz H.H. Cocoa antioxidants and cardiovascular health. American Journal of Clinical Nutrition 2005, 81:298S-303S. (Suppl.).
30. Kitchin K.T. Recent advances in arsenic carcinogenesis: Modes of action, animal model systems and methylated arsenic metabolites. Toxicology and Applied Pharmacology 2001, 172:249-261.
31. Lamuela-Raventós R.M., Romero-Pérez A.I., Andrés-Lacueva C., Tornero A. Review: Health effects of cocoa flavonoids. Food Science and Technology International 2005, 11:159-176.
32. Lowry O.H., Rosenberg N.J., Farr A.L., Randal R.J. Protein measurement with the Folin-Phenol reagent. The Journal of Biological Chemistry 1951, 193:265-275.
33. McDonald S., Prenzler P.D., Autolovich M., Robards K. Phenolic content and antioxidant activity of olive extracts. Food Chemistry 2001, 73:73-84.
34. Meliker J.R., Wahl R.L., Cameron L.L., Nriagu J.O. Arsenic in drinking water and cerebrovascular disease, diabetes mellitus, and kidney disease in Michigan: A standardized mortality ratio analysis. Environmental Health 2007, 6:4.
35. Mishra D., Mehta A., Flora S.J.S. Reversal of arsenic induced hepatic apoptosis with combined administration DMSA and its analogue in Guinea pigs: Role of glutathione and linked enzymes. Chemical Research in Toxicology 2008, 21:400-407.
36. Moren M.S., Desplerra J.W., Mannervick B. Levels of glutathione, glutathione reductase and glutathione S transferase activity in rat liver and lung. Biochimica et Biophysica Acta 1979, 585:67.
37. Nandi D., Patra R.C., Swarup D. Oxidative stress indices and plasma biochemical parameters during oral exposure to arsenic in rats. Food and Chemical Toxicology 2006, 44:1579-1584.
38. Ohkawa H., Ohishi N., Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Annals of Biochemistry 1979, 95:351-358.
39. Orozco T., Wang J.F., Keen C.L. Chronic consumption of a flavanol- and procyanindin-rich diet is associated with reduced levels of 8-hydroxy- 2'-deoxyguanosine in rat testes. The Journal of Nutritional Biochemistry 2003, 14:104-110.
40. Ortega N., Romero M.P., Macia A., Reguant J., Angles N., Morello J.R., et al. Obtention and characterisation of phenolic extracts from different cocoa sources. Journal of Agricultural and Food Chemistry 2008, 56:9621-9627.
41. Osakabe N., Yamagishi M., Natsume M., Yasuda A., Osawa T. Ingestion of proanthocyanidins derived from cacao inhibits diabetes-induced cataract formation in rats. Experimental Biology and Medicine 2004, 229:33-39.
42. Park E.M., Ramnath N., Yang G.Y., Ahn J.Y., Park Y., Lee T.Y., et al. High SOD and low GPx activities in RBC predict susceptibility of lung cancer patients to radiation pneumonitis. Free Radical Biology & Medicine 2007, 42(2):280-287.
43. Ramiro Puig E., Urpí-Sardá M., Pérez-Cano F.J., Franch A., Castellote C., Andrés- Lacueva C., et al. Cocoa-enriched diet enhances antioxidant enzyme activity and modulates lymphocyte composition in thymus from young rats. Journal of Agricultural and Food Chemistry 2007, 55:6431-6438.
44. Rana T., Bera A.K., Das S., Bhattacharya D., Pan D., Bandyopadhyay S., et al. Mushroom lectin protects arsenic induced apoptosis in hepatocytes of rodents. Human and Experimental Toxicology 2011, 30(4):307-317.
45. Rana T., Bera A.K., Das S., Pan D., Bandyopadhyay S., Bhattacharya D., et al. Supplementation of ascorbic acid prevents oxidative damages in arsenic-loaded hepatic tissue of rat: An ex vivo study. Human and Experimental Toxicology 2010, 29(11):965-972.
46. Rotruck J.T., Pope A.L., Ganther H.E., Swaason A.B., Hafeman D.G., Hoekstra W.G. Selenium biochemical role as a component of glutathione peroxide purification and assay. Science 1973, 179:588.
47. Ruzaidi A., Amin I., Nawalyah A.G., Hamid M., Faizul H.A. The effect of Malaysian cocoa extract on glucose levels and lipid profiles in diabetic rats. Journal of Ethnopharmacology 2005, 98:55-60.
48. Sanchez Rabaneda F., Jauregui O., Casals I., Andres Lacueva C., Izquierdo Pulido M., Lamuela Raventos R.M. Liquid chromatography/electrospray ionization tandem mass spectrometric study of the phenolic composition of cocoa (Theobroma cacao). Journal of Mass Spectrometry 2003, 38:35-42.
49. Sarmadi B., Ismail A., Hamid M. Antioxidant and angiotensin converting enzyme (ACE) inhibitory activities of cocoa (Theobroma cacao L.) autolysates. Food Research International 2011, 44:290-296.
50. Shi H., Shi X., Liu K.J. Oxidative mechanism of arsenic toxicity and carcinogenesis. Molecular and Cellular Biochemistry 2004, 255:67-78.
51. Shiobara Y., Ogra Y., Suzuki K.T. Animal species difference in the uptake of dimethylarsinous acid (dma(iii)) by red blood cells. Chemical Research in Toxicology 2001, 14:1446-1452.
52. Swaran Flora J.S., Smrati Bhadauria T., Satish C.P., Ram K.D. Arsenic induced blood and brain oxidative stress and its response to some thiol chelators in rats. Life Sciences 2005, 77:2324-2337.
53. Tafuri A., Ferracane R., Ritieni A. Ochratoxin A in Italian marketed cocoa products. Food Chemistry 2004, 88:487-494.
54. Tapio S., Grosche B. Arsenic in the aetiology of cancer. Mutation Research 2006, 612:215-246.
55. Thomas D.J., Styblo M., Lin S. The cellular metabolism and systemic toxicity of arsenic. Toxicology and Applied Pharmacology 2001, 176:127-144.
56. Vahter M. Mechanism of arsenic biotransformation. Toxicology 2002, 211:181-182.
57. Wang J.F., Schramm D.D., Holt R.R., Ensunsa J.L., Fraga C.G., Schmitz H.H., et al. A dose-response effect from chocolate consumption on plasma epicatechin and oxidative damage. Journal of Nutrition 2000, 130:2115S-2119S.
58. Wollgast J., Anklam E. Polyphenols in chocolate: Is there a contribution to human health?. Food Research International 2000, 33:449-459.
59. I.A.R.C.Working Group on the Evaluation of Carcinogenic Risks to Humans Some drinking-water disinfectants and contaminants, including arsenic. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans 2004, 84:1-477.