Altering TET dioxygenase levels within physiological range affects DNA methylation dynamics of HEK293 cells

Epigenetics

Volumn 10, Issue 9, 2015, Pages 819-833

  Grosser, Christian ^a   Wagner, Nicholas ^a   Grothaus, Katrin ^a   Horsthemke, Bernhard ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

450K; Demethylation; Epigenetics; Hydroxymethylcytosine; Methylcytosine; RRHP; TET1; TET2; TET3

Indexed keywords

DIOXYGENASE; TEN ELEVEN TRANSLOCATION DIOXYGENASE; TEN ELEVEN TRANSLOCATION DIOXYGENASE 1; TEN ELEVEN TRANSLOCATION DIOXYGENASE 2; TEN ELEVEN TRANSLOCATION DIOXYGENASE 3; UNCLASSIFIED DRUG; 5-HYDROXYMETHYLCYTOSINE; CYTOSINE; DNA BINDING PROTEIN; MIXED FUNCTION OXIDASE; ONCOPROTEIN; TET1 PROTEIN, HUMAN; TET2 PROTEIN, HUMAN; TET3 PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DOWN REGULATION; EPIGENETICS; GENE EXPRESSION; GENE ONTOLOGY; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; NEXT GENERATION SEQUENCING; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; GENE SILENCING; GENETICS; HEK293 CELL LINE; METABOLISM; PROMOTER REGION;

CPG ISLANDS; CYTOSINE; DIOXYGENASES; DNA METHYLATION; DNA-BINDING PROTEINS; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HUMANS; MIXED FUNCTION OXYGENASES; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS; UP-REGULATION;

EID: 84954540490     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.1080/15592294.2015.1073879     Document Type: Article

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