tRNA processing defects induce replication stress and Chk2-dependent disruption of piRNA transcription

EMBO Journal

Volumn 34, Issue 24, 2015, Pages 3009-3027

  Molla Herman, Anahi ^a,b   Vallés, Ana Maria ^a,b   Ganem Elbaz, Carine ^a,b   Antoniewski, Christophe ^c   Huynh, Jean René ^a,b  

^a INSTITUT CURIE   (France)

^b CNRS   (France)

^c Sorbonne Universités   (France)

Author keywords

Drosophila; dysgenesis; heterochromatin; oogenesis; transposon

Indexed keywords

CHECKPOINT KINASE 2; PIWI INTERACTING RNA; RIBONUCLEASE P; TRANSFER RNA; CELL CYCLE PROTEIN; CLASPIN PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN; HETEROCHROMATIN; HISTONE; LOK PROTEIN, DROSOPHILA; PROTEIN P53; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA DAMAGE CHECKPOINT; DNA REPLICATION; DROSOPHILA; FEMALE; FERTILITY; GENE MUTATION; GENOME ANALYSIS; GERM CELL; HUMAN; HUMAN CELL; NONHUMAN; OOCYTE DEVELOPMENT; OVARY; PRIORITY JOURNAL; STRESS; TRANSPOSON; ANIMAL; CYTOLOGY; DNA DAMAGE; DROSOPHILA MELANOGASTER; FEMALE INFERTILITY; GENETICS; HETEROCHROMATIN; METABOLISM; RNA PROCESSING;

ANIMALS; CELL CYCLE PROTEINS; CHECKPOINT KINASE 2; DNA DAMAGE; DNA REPLICATION; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; HETEROCHROMATIN; HISTONES; INFERTILITY, FEMALE; OVARY; RIBONUCLEASE P; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, SMALL INTERFERING; RNA, TRANSFER; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84954511723     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201591006     Document Type: Article

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