-
1
-
-
84896690513
-
Prevalence of childhood and adult obesity in the United States, 2011-2012
-
Ogden, C. L., Carroll, M. D., Kit, B. K., and Flegal, K. M. (2014) Prevalence of childhood and adult obesity in the United States, 2011-2012. JAMA 311, 806-814
-
(2014)
JAMA
, vol.311
, pp. 806-814
-
-
Ogden, C.L.1
Carroll, M.D.2
Kit, B.K.3
Flegal, K.M.4
-
2
-
-
0026468362
-
What if minkowski had been ageusic? An alternative angle on diabetes
-
McGarry, J. D. (1992) What if Minkowski had been ageusic? An alternative angle on diabetes. Science 258, 766-770
-
(1992)
Science
, vol.258
, pp. 766-770
-
-
McGarry, J.D.1
-
3
-
-
0031887281
-
Role of human liver lipogenesis and reesterification in triglycerides secretion and in FFA reesterification
-
Diraison, F., and Beylot, M. (1998) Role of human liver lipogenesis and reesterification in triglycerides secretion and in FFA reesterification. Am. J. Physiol. 274, E321-E327
-
(1998)
Am. J. Physiol.
, vol.274
, pp. E321-E327
-
-
Diraison, F.1
Beylot, M.2
-
4
-
-
38649116056
-
Selective versus total insulin resistance: A pathogenic paradox
-
Brown, M. S., and Goldstein, J. L. (2008) Selective versus total insulin resistance: a pathogenic paradox. Cell Metab. 7, 95-96
-
(2008)
Cell Metab.
, vol.7
, pp. 95-96
-
-
Brown, M.S.1
Goldstein, J.L.2
-
5
-
-
33845587711
-
Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice
-
Chen, W., Chen, G., Head, D. L., Mangelsdorf, D. J., and Russell, D. W. (2007) Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice. Cell Metab. 5, 73-79
-
(2007)
Cell Metab.
, vol.5
, pp. 73-79
-
-
Chen, W.1
Chen, G.2
Head, D.L.3
Mangelsdorf, D.J.4
Russell, D.W.5
-
6
-
-
0037192797
-
Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors
-
Joseph, S. B., Laffitte, B. A., Patel, P. H., Watson, M. A., Matsukuma, K. E., Walczak, R., Collins, J. L., Osborne, T. F., and Tontonoz, P. (2002) Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors. J. Biol. Chem. 277, 11019-11025
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 11019-11025
-
-
Joseph, S.B.1
Laffitte, B.A.2
Patel, P.H.3
Watson, M.A.4
Matsukuma, K.E.5
Walczak, R.6
Collins, J.L.7
Osborne, T.F.8
Tontonoz, P.9
-
7
-
-
0034669025
-
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ 1
-
Repa, J. J., Liang, G., Ou, J., Bashmakov, Y., Lobaccaro, J. M., Shimomura, I., Shan, B., Brown, M. S., Goldstein, J. L., and Mangelsdorf, D. J. (2000) Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ 1. Genes Dev. 14, 2819-2830
-
(2000)
Genes Dev.
, vol.14
, pp. 2819-2830
-
-
Repa, J.J.1
Liang, G.2
Ou, J.3
Bashmakov, Y.4
Lobaccaro, J.M.5
Shimomura, I.6
Shan, B.7
Brown, M.S.8
Goldstein, J.L.9
Mangelsdorf, D.J.10
-
8
-
-
33847006599
-
The liver X receptor (LXR) and hepatic lipogenesis: The carbohydrate-response element-binding protein is a target gene of LXR
-
Cha, J. Y., and Repa, J. J. (2007) The liver X receptor (LXR) and hepatic lipogenesis: the carbohydrate-response element-binding protein is a target gene of LXR. J. Biol. Chem. 282, 743-751
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 743-751
-
-
Cha, J.Y.1
Repa, J.J.2
-
9
-
-
0036251153
-
SREBPs: Activators of the complete program of cholesterol and fatty acid synthesis in the liver
-
Horton, J. D., Goldstein, J. L., and Brown, M. S. (2002) SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J. Clin. Invest. 109, 1125-1131
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 1125-1131
-
-
Horton, J.D.1
Goldstein, J.L.2
Brown, M.S.3
-
10
-
-
0030907175
-
Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells
-
Shimano, H., Horton, J. D., Shimomura, I., Hammer, R. E., Brown, M. S., and Goldstein, J. L. (1997) Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells. J. Clin. Invest. 99, 846-854
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 846-854
-
-
Shimano, H.1
Horton, J.D.2
Shimomura, I.3
Hammer, R.E.4
Brown, M.S.5
Goldstein, J.L.6
-
11
-
-
0037088683
-
Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c
-
Liang, G., Yang, J., Horton, J. D., Hammer, R. E., Goldstein, J. L., and Brown, M. S. (2002) Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c. J. Biol. Chem. 277, 9520-9528
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 9520-9528
-
-
Liang, G.1
Yang, J.2
Horton, J.D.3
Hammer, R.E.4
Goldstein, J.L.5
Brown, M.S.6
-
12
-
-
0035979214
-
A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver
-
Yamashita, H., Takenoshita, M., Sakurai, M., Bruick, R. K., Henzel, W. J., Shillinglaw, W., Arnot, D., and Uyeda, K. (2001) A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver. Proc. Natl. Acad. Sci. U.S.A. 98, 9116-9121
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 9116-9121
-
-
Yamashita, H.1
Takenoshita, M.2
Sakurai, M.3
Bruick, R.K.4
Henzel, W.J.5
Shillinglaw, W.6
Arnot, D.7
Uyeda, K.8
-
13
-
-
0034669171
-
Role of LXRs in control of lipogenesis
-
Schultz, J. R., Tu, H., Luk, A., Repa, J. J., Medina, J. C., Li, L., Schwendner, S., Wang, S., Thoolen, M., Mangelsdorf, D. J., Lustig, K. D., and Shan, B. (2000) Role of LXRs in control of lipogenesis. Genes Dev. 14, 2831-2838
-
(2000)
Genes Dev.
, vol.14
, pp. 2831-2838
-
-
Schultz, J.R.1
Tu, H.2
Luk, A.3
Repa, J.J.4
Medina, J.C.5
Li, L.6
Schwendner, S.7
Wang, S.8
Thoolen, M.9
Mangelsdorf, D.J.10
Lustig, K.D.11
Shan, B.12
-
14
-
-
0013199471
-
Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXRα
-
Peet, D. J., Turley, S. D., Ma, W., Janowski, B. A., Lobaccaro, J. M., Hammer, R. E., and Mangelsdorf, D. J. (1998) Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXRα. Cell 93, 693-704
-
(1998)
Cell
, vol.93
, pp. 693-704
-
-
Peet, D.J.1
Turley, S.D.2
Ma, W.3
Janowski, B.A.4
Lobaccaro, J.M.5
Hammer, R.E.6
Mangelsdorf, D.J.7
-
15
-
-
0037324340
-
Reciprocal regulation of inflammation and lipid metabolism by liver X receptors
-
Joseph, S. B., Castrillo, A., Laffitte, B. A., Mangelsdorf, D. J., and Tontonoz, P. (2003) Reciprocal regulation of inflammation and lipid metabolism by liver X receptors. Nat. Med. 9, 213-219
-
(2003)
Nat. Med.
, vol.9
, pp. 213-219
-
-
Joseph, S.B.1
Castrillo, A.2
Laffitte, B.A.3
Mangelsdorf, D.J.4
Tontonoz, P.5
-
16
-
-
84887440152
-
LXRs regulate ER stress and inflammation through dynamic modulation of membrane phospholipid composition
-
Rong, X., Albert, C. J., Hong, C., Duerr, M. A., Chamberlain, B. T., Tarling, E. J., Ito, A., Gao, J., Wang, B., Edwards, P. A., Jung, M. E., Ford, D. A., and Tontonoz, P. (2013) LXRs regulate ER stress and inflammation through dynamic modulation of membrane phospholipid composition. Cell Metab. 18, 685-697
-
(2013)
Cell Metab.
, vol.18
, pp. 685-697
-
-
Rong, X.1
Albert, C.J.2
Hong, C.3
Duerr, M.A.4
Chamberlain, B.T.5
Tarling, E.J.6
Ito, A.7
Gao, J.8
Wang, B.9
Edwards, P.A.10
Jung, M.E.11
Ford, D.A.12
Tontonoz, P.13
-
17
-
-
84933039116
-
Liver X receptor activation promotes polyunsaturated fatty acid synthesis in macrophages: Relevance in the context of atherosclerosis
-
Varin, A., Thomas, C., Ishibashi, M., Ménégaut, L., Gautier, T., Trousson, A., Bergas, V., de Barros, J. P., Narce, M., Lobaccaro, J. M., Lagrost, L., and Masson, D. (2015) Liver X receptor activation promotes polyunsaturated fatty acid synthesis in macrophages: relevance in the context of atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 35, 1357-1365
-
(2015)
Arterioscler. Thromb. Vasc. Biol.
, vol.35
, pp. 1357-1365
-
-
Varin, A.1
Thomas, C.2
Ishibashi, M.3
Ménégaut, L.4
Gautier, T.5
Trousson, A.6
Bergas, V.7
De Barros, J.P.8
Narce, M.9
Lobaccaro, J.M.10
Lagrost, L.11
Masson, D.12
-
18
-
-
84879099171
-
Liver X receptor regulates arachidonic acid distribution and eicosanoid release in human macrophages: A key role for lysophosphatidylcholine acyltransferase 3
-
Ishibashi, M., Varin, A., Filomenko, R., Lopez, T., Athias, A., Gambert, P., Blache, D., Thomas, C., Gautier, T., Lagrost, L., and Masson, D. (2013) Liver X receptor regulates arachidonic acid distribution and eicosanoid release in human macrophages: a key role for lysophosphatidylcholine acyltransferase 3. Arterioscler. Thromb. Vasc. Biol. 33, 1171-1179
-
(2013)
Arterioscler. Thromb. Vasc. Biol.
, vol.33
, pp. 1171-1179
-
-
Ishibashi, M.1
Varin, A.2
Filomenko, R.3
Lopez, T.4
Athias, A.5
Gambert, P.6
Blache, D.7
Thomas, C.8
Gautier, T.9
Lagrost, L.10
Masson, D.11
-
19
-
-
43749115983
-
Identification and characterization of a major liver lysophosphatidylcholine acyltransferase
-
Zhao, Y., Chen, Y. Q., Bonacci, T. M., Bredt, D. S., Li, S., Bensch, W. R., Moller, D. E., Kowala, M., Konrad, R. J., and Cao, G. (2008) Identification and characterization of a major liver lysophosphatidylcholine acyltransferase. J. Biol. Chem. 283, 8258-8265
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 8258-8265
-
-
Zhao, Y.1
Chen, Y.Q.2
Bonacci, T.M.3
Bredt, D.S.4
Li, S.5
Bensch, W.R.6
Moller, D.E.7
Kowala, M.8
Konrad, R.J.9
Cao, G.10
-
20
-
-
0033636523
-
Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction
-
Michael, M. D., Kulkarni, R. N., Postic, C., Previs, S. F., Shulman, G. I., Magnuson, M. A., and Kahn, C. R. (2000) Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction. Mol. Cell 6, 87-97
-
(2000)
Mol. Cell
, vol.6
, pp. 87-97
-
-
Michael, M.D.1
Kulkarni, R.N.2
Postic, C.3
Previs, S.F.4
Shulman, G.I.5
Magnuson, M.A.6
Kahn, C.R.7
-
21
-
-
38649110496
-
Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis
-
Biddinger, S. B., Hernandez-Ono, A., Rask-Madsen, C., Haas, J. T., Alemán, J. O., Suzuki, R., Scapa, E. F., Agarwal, C., Carey, M. C., Stephanopoulos, G., Cohen, D. E., King, G. L., Ginsberg, H. N., and Kahn, C. R. (2008) Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis. Cell Metab. 7, 125-134
-
(2008)
Cell Metab.
, vol.7
, pp. 125-134
-
-
Biddinger, S.B.1
Hernandez-Ono, A.2
Rask-Madsen, C.3
Haas, J.T.4
Alemán, J.O.5
Suzuki, R.6
Scapa, E.F.7
Agarwal, C.8
Carey, M.C.9
Stephanopoulos, G.10
Cohen, D.E.11
King, G.L.12
Ginsberg, H.N.13
Kahn, C.R.14
-
22
-
-
84862023939
-
Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression
-
Haas, J. T., Miao, J., Chanda, D., Wang, Y., Zhao, E., Haas, M. E., Hirschey, M., Vaitheesvaran, B., Farese, R. V., Jr., Kurland, I. J., Graham, M., Crooke, R., Foufelle, F., and Biddinger, S. B. (2012) Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression. Cell Metab. 15, 873-884
-
(2012)
Cell Metab.
, vol.15
, pp. 873-884
-
-
Haas, J.T.1
Miao, J.2
Chanda, D.3
Wang, Y.4
Zhao, E.5
Haas, M.E.6
Hirschey, M.7
Vaitheesvaran, B.8
Farese, R.V.9
Kurland, I.J.10
Graham, M.11
Crooke, R.12
Foufelle, F.13
Biddinger, S.B.14
-
23
-
-
84897387992
-
Hepatic insulin receptor deficiency impairs the SREBP-2 response to feeding and statins
-
Miao, J., Haas, J. T., Manthena, P., Wang, Y., Zhao, E., Vaitheesvaran, B., Kurland, I. J., and Biddinger, S. B. (2014) Hepatic insulin receptor deficiency impairs the SREBP-2 response to feeding and statins. J. Lipid Res. 55, 659-667
-
(2014)
J. Lipid Res.
, vol.55
, pp. 659-667
-
-
Miao, J.1
Haas, J.T.2
Manthena, P.3
Wang, Y.4
Zhao, E.5
Vaitheesvaran, B.6
Kurland, I.J.7
Biddinger, S.B.8
-
24
-
-
84927126803
-
Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis
-
Miao, J., Ling, A. V., Manthena, P. V., Gearing, M. E., Graham, M. J., Crooke, R. M., Croce, K. J., Esquejo, R. M., Clish, C. B., Morbid Obesity Study Group, Vicent, D., and Biddinger, S. B. (2015) Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis. Nat. Commun. 6, 6498
-
(2015)
Nat. Commun.
, vol.6
, pp. 6498
-
-
Miao, J.1
Ling, A.V.2
Manthena, P.V.3
Gearing, M.E.4
Graham, M.J.5
Crooke, R.M.6
Croce, K.J.7
Esquejo, R.M.8
Clish, C.B.9
Vicent, D.10
Biddinger, S.B.11
-
25
-
-
70449158340
-
A simple method for the isolation and purification of total lipides from animal tissues
-
Folch, J., Lees, M., and Sloane Stanley, G. H. (1957) A simple method for the isolation and purification of total lipides from animal tissues. J. Biol. Chem. 226, 497-509
-
(1957)
J. Biol. Chem.
, vol.226
, pp. 497-509
-
-
Folch, J.1
Lees, M.2
Sloane Stanley, G.H.3
-
26
-
-
33645982255
-
From mice to men: Insights into the insulin resistance syndromes
-
Biddinger, S. B., and Kahn, C. R. (2006) From mice to men: insights into the insulin resistance syndromes. Annu Rev. Physiol. 68, 123-158
-
(2006)
Annu Rev. Physiol.
, vol.68
, pp. 123-158
-
-
Biddinger, S.B.1
Kahn, C.R.2
-
27
-
-
84890319075
-
Characterization of target mRNA reduction through in situ RNA hybridization in multiple organ systems following systemic antisense treatment in animals
-
Hung, G., Xiao, X., Peralta, R., Bhattacharjee, G., Murray, S., Norris, D., Guo, S., and Monia, B. P. (2013) Characterization of target mRNA reduction through in situ RNA hybridization in multiple organ systems following systemic antisense treatment in animals. Nucleic Acid Ther. 23, 369-378
-
(2013)
Nucleic Acid Ther.
, vol.23
, pp. 369-378
-
-
Hung, G.1
Xiao, X.2
Peralta, R.3
Bhattacharjee, G.4
Murray, S.5
Norris, D.6
Guo, S.7
Monia, B.P.8
-
28
-
-
2942588527
-
Stearoyl-CoA desaturase 1 gene expression is necessary for fructose-mediated induction of lipogenic gene expression by sterol regulatory element-binding protein-1c-dependent and -independent mechanisms
-
Miyazaki, M., Dobrzyn, A., Man, W. C., Chu, K., Sampath, H., Kim, H. J., and Ntambi, J. M. (2004) Stearoyl-CoA desaturase 1 gene expression is necessary for fructose-mediated induction of lipogenic gene expression by sterol regulatory element-binding protein-1c-dependent and -independent mechanisms. J. Biol. Chem. 279, 25164-25171
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 25164-25171
-
-
Miyazaki, M.1
Dobrzyn, A.2
Man, W.C.3
Chu, K.4
Sampath, H.5
Kim, H.J.6
Ntambi, J.M.7
-
29
-
-
54449094904
-
Lxrα deficiency hampers the hepatic adaptive response to fasting in mice
-
Oosterveer, M. H., van Dijk, T. H., Grefhorst, A., Bloks, V. W., Havinga, R., Kuipers, F., and Reijngoud, D. J. (2008) Lxrα deficiency hampers the hepatic adaptive response to fasting in mice. J. Biol. Chem. 283, 25437-25445
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 25437-25445
-
-
Oosterveer, M.H.1
Van Dijk, T.H.2
Grefhorst, A.3
Bloks, V.W.4
Havinga, R.5
Kuipers, F.6
Reijngoud, D.J.7
-
30
-
-
46749094102
-
Hepatic insulin resistance directly promotes formation of cholesterol gallstones
-
Biddinger, S. B., Haas, J. T., Yu, B. B., Bezy, O., Jing, E., Zhang, W., Unterman, T. G., Carey, M. C., and Kahn, C. R. (2008) Hepatic insulin resistance directly promotes formation of cholesterol gallstones. Nat. Med. 14, 778-782
-
(2008)
Nat. Med.
, vol.14
, pp. 778-782
-
-
Biddinger, S.B.1
Haas, J.T.2
Yu, B.B.3
Bezy, O.4
Jing, E.5
Zhang, W.6
Unterman, T.G.7
Carey, M.C.8
Kahn, C.R.9
-
31
-
-
0037372065
-
The phospholipid transfer protein gene is a liver X receptor target expressed by macrophages in atherosclerotic lesions
-
Laffitte, B. A., Joseph, S. B., Chen, M., Castrillo, A., Repa, J., Wilpitz, D., Mangelsdorf, D., and Tontonoz, P. (2003) The phospholipid transfer protein gene is a liver X receptor target expressed by macrophages in atherosclerotic lesions. Mol. Cell. Biol. 23, 2182-2191
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 2182-2191
-
-
Laffitte, B.A.1
Joseph, S.B.2
Chen, M.3
Castrillo, A.4
Repa, J.5
Wilpitz, D.6
Mangelsdorf, D.7
Tontonoz, P.8
-
32
-
-
0037131347
-
Phospholipid transfer protein is regulated by liver X receptors in vivo
-
Cao, G., Beyer, T. P., Yang, X. P., Schmidt, R. J., Zhang, Y., Bensch, W. R., Kauffman, R. F., Gao, H., Ryan, T. P., Liang, Y., Eacho, P. I., and Jiang, X. C. (2002) Phospholipid transfer protein is regulated by liver X receptors in vivo. J. Biol. Chem. 277, 39561-39565
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 39561-39565
-
-
Cao, G.1
Beyer, T.P.2
Yang, X.P.3
Schmidt, R.J.4
Zhang, Y.5
Bensch, W.R.6
Kauffman, R.F.7
Gao, H.8
Ryan, T.P.9
Liang, Y.10
Eacho, P.I.11
Jiang, X.C.12
-
33
-
-
84883295520
-
Liver-specific phospholipid transfer protein deficiency reduces high-density lipoprotein and non-high-density lipoprotein production in mice
-
Yazdanyar, A., Quan, W., Jin, W., and Jiang, X. C. (2013) Liver-specific phospholipid transfer protein deficiency reduces high-density lipoprotein and non-high-density lipoprotein production in mice. Arterioscler. Thromb. Vasc. Biol. 33, 2058-2064
-
(2013)
Arterioscler. Thromb. Vasc. Biol.
, vol.33
, pp. 2058-2064
-
-
Yazdanyar, A.1
Quan, W.2
Jin, W.3
Jiang, X.C.4
-
34
-
-
77949898756
-
LXRSREBP-1c-phospholipid transfer protein axis controls very low density lipoprotein (VLDL) particle size
-
Okazaki, H., Goldstein, J. L., Brown, M. S., and Liang, G. (2010) LXRSREBP-1c-phospholipid transfer protein axis controls very low density lipoprotein (VLDL) particle size. J. Biol. Chem. 285, 6801-6810
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 6801-6810
-
-
Okazaki, H.1
Goldstein, J.L.2
Brown, M.S.3
Liang, G.4
-
35
-
-
12744271884
-
Insulin activates the rat sterol-regulatory-element-binding protein 1c (SREBP-1c) promoter through the combinatorial actions of SREBP, LXR, Sp-1 and NF-Y cis-acting elements 1
-
Cagen, L. M., Deng, X., Wilcox, H. G., Park, E. A., Raghow, R., and Elam, M. B. (2005) Insulin activates the rat sterol-regulatory-element-binding protein 1c (SREBP-1c) promoter through the combinatorial actions of SREBP, LXR, Sp-1 and NF-Y cis-acting elements 1. Biochem. J. 385, 207-216
-
(2005)
Biochem. J.
, vol.385
, pp. 207-216
-
-
Cagen, L.M.1
Deng, X.2
Wilcox, H.G.3
Park, E.A.4
Raghow, R.5
Elam, M.B.6
-
36
-
-
0037453007
-
Liver-specific mRNA for insig-2 down-regulated by insulin: Implications for fatty acid synthesis
-
Yabe, D., Komuro, R., Liang, G., Goldstein, J. L., and Brown, M. S. (2003) Liver-specific mRNA for Insig-2 down-regulated by insulin: implications for fatty acid synthesis. Proc. Natl. Acad. Sci. U.S.A. 100, 3155-3160
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 3155-3160
-
-
Yabe, D.1
Komuro, R.2
Liang, G.3
Goldstein, J.L.4
Brown, M.S.5
-
37
-
-
23844530704
-
Fbw7
-
Fbw7. Cell Metab. 1, 379-391
-
(2005)
Cell Metab.
, vol.1
, pp. 379-391
-
-
Sundqvist, A.1
Bengoechea-Alonso, M.T.2
Ye, X.3
Lukiyanchuk, V.4
Jin, J.5
Harper, J.W.6
Ericsson, J.7
-
38
-
-
14144251157
-
Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory element-binding protein-1c
-
Hegarty, B. D., Bobard, A., Hainault, I., Ferré, P., Bossard, P., and Foufelle, F. (2005) Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory element-binding protein-1c. Proc. Natl. Acad. Sci. U.S.A. 102, 791-796
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 791-796
-
-
Hegarty, B.D.1
Bobard, A.2
Hainault, I.3
Ferré, P.4
Bossard, P.5
Foufelle, F.6
-
39
-
-
0043133791
-
Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression
-
Wagner, B. L., Valledor, A. F., Shao, G., Daige, C. L., Bischoff, E. D., Petrowski, M., Jepsen, K., Baek, S. H., Heyman, R. A., Rosenfeld, M. G., Schulman, I. G., and Glass, C. K. (2003) Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression. Mol. Cell. Biol. 23, 5780-5789
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 5780-5789
-
-
Wagner, B.L.1
Valledor, A.F.2
Shao, G.3
Daige, C.L.4
Bischoff, E.D.5
Petrowski, M.6
Jepsen, K.7
Baek, S.H.8
Heyman, R.A.9
Rosenfeld, M.G.10
Schulman, I.G.11
Glass, C.K.12
-
40
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
Ozcan, U., Cao, Q., Yilmaz, E., Lee, A. H., Iwakoshi, N. N., Ozdelen, E., Tuncman, G., Görgün, C., Glimcher, L. H., and Hotamisligil, G. S. (2004) Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 306, 457-461
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
Lee, A.H.4
Iwakoshi, N.N.5
Ozdelen, E.6
Tuncman, G.7
Görgün, C.8
Glimcher, L.H.9
Hotamisligil, G.S.10
-
41
-
-
33745861300
-
Inflammation and insulin resistance
-
Shoelson, S. E., Lee, J., and Goldfine, A. B. (2006) Inflammation and insulin resistance. J. Clin. Invest. 116, 1793-1801
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1793-1801
-
-
Shoelson, S.E.1
Lee, J.2
Goldfine, A.B.3
-
42
-
-
65549094721
-
Reverse cholesterol transport in type 2 diabetes mellitus
-
Tan, K. C. (2009) Reverse cholesterol transport in type 2 diabetes mellitus. Diabetes Obes. Metab. 11, 534-543
-
(2009)
Diabetes Obes. Metab.
, vol.11
, pp. 534-543
-
-
Tan, K.C.1
|