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Volumn 22, Issue 2, 2016, Pages 862-873

Status of hepatitis C virus vaccination: Recent update

Author keywords

Clinical trials; Hepatitis C; Hepatitis C virus vaccine; Immune response; Viral envelope glycoproteins

Indexed keywords

DNA VACCINE; HEPATITIS C VACCINE; PEPTIDE VACCINE; RECOMBINANT PROTEIN; RECOMBINANT VACCINE; SYNTHETIC PEPTIDE; VIRUS VECTOR; HEPATITIS VACCINE;

EID: 84954436919     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v22.i2.862     Document Type: Review
Times cited : (25)

References (104)
  • 1
    • 63849329322 scopus 로고    scopus 로고
    • Development of hepatitis C virus vaccines: Challenges and progress
    • PMID: 19249975
    • Stoll-Keller F, Barth H, Fafi-Kremer S, Zeisel MB, Baumert TF. Development of hepatitis C virus vaccines: challenges and progress. Expert Rev Vaccines 2009; 8: 333-345 [PMID: 19249975 DOI: 10.1586/14760584.8.3.333]
    • (2009) Expert Rev Vaccines , vol.8 , pp. 333-345
    • Stoll-Keller, F.1    Barth, H.2    Fafi-Kremer, S.3    Zeisel, M.B.4    Baumert, T.F.5
  • 2
    • 34748873170 scopus 로고    scopus 로고
    • Flaviviridae: The viruses and their replication
    • Knipe DM, Howley PM, editors Philadelphia: Lippincott-Raven Publishers
    • Lindenbach BD, Thiel HJ, Rice CM. Flaviviridae: the viruses and their replication. In: Knipe DM, Howley PM, editors. Fields Virology. 5th ed. Philadelphia: Lippincott-Raven Publishers, 2007: 1101-1152
    • (2007) Fields Virology. 5th Ed , pp. 1101-1152
    • Lindenbach, B.D.1    Thiel, H.J.2    Rice, C.M.3
  • 4
    • 82155191792 scopus 로고    scopus 로고
    • Neutralizing antibody response to hepatitis C virus
    • PMID: 22163337
    • Wang Y, Keck ZY, Foung SK. Neutralizing antibody response to hepatitis C virus. Viruses 2011; 3: 2127-2145 [PMID: 22163337 DOI: 10.3390/v3112127]
    • (2011) Viruses , vol.3 , pp. 2127-2145
    • Wang, Y.1    Keck, Z.Y.2    Foung, S.K.3
  • 6
    • 79958780802 scopus 로고    scopus 로고
    • Perspective: Test and treat this silent killer
    • PMID: 21613999
    • Edlin BR. Perspective: test and treat this silent killer. Nature 2011; 474: S18-S19 [PMID: 21613999 DOI: 10.1038/474S18a]
    • (2011) Nature , vol.474 , pp. S18-S19
    • Edlin, B.R.1
  • 7
    • 77956168246 scopus 로고    scopus 로고
    • Meta-analysis of hepatitis C virus vaccine effcacy in chimpanzees indicates an importance for structural proteins
    • PMID: 20621699
    • Dahari H, Feinstone SM, Major ME. Meta-analysis of hepatitis C virus vaccine effcacy in chimpanzees indicates an importance for structural proteins. Gastroenterology 2010; 139: 965-974 [PMID: 20621699 DOI: 10.1053/j.gastro.2010.05.077]
    • (2010) Gastroenterology , vol.139 , pp. 965-974
    • Dahari, H.1    Feinstone, S.M.2    Major, M.E.3
  • 9
    • 0032475822 scopus 로고    scopus 로고
    • Hepatitis C viral dynamics in vivo and the antiviral effcacy of interferon-alpha therapy
    • PMID: 9756471
    • Neumann AU, Lam NP, Dahari H, Gretch DR, Wiley TE, Layden TJ, Perelson AS. Hepatitis C viral dynamics in vivo and the antiviral effcacy of interferon-alpha therapy. Science 1998; 282: 103-107 [PMID: 9756471]
    • (1998) Science , vol.282 , pp. 103-107
    • Neumann, A.U.1    Lam, N.P.2    Dahari, H.3    Gretch, D.R.4    Wiley, T.E.5    Layden, T.J.6    Perelson, A.S.7
  • 10
    • 7444256169 scopus 로고    scopus 로고
    • Genetic diversity and evolution of hepatitis C virus-15 years on
    • PMID: 15483230
    • Simmonds P. Genetic diversity and evolution of hepatitis C virus-15 years on. J Gen Virol 2004; 85: 3173-3188 [PMID: 15483230]
    • (2004) J Gen Virol , vol.85 , pp. 3173-3188
    • Simmonds, P.1
  • 11
    • 0037057124 scopus 로고    scopus 로고
    • Genetic diversity and models of viral evolution for the hepatitis C virus
    • PMID: 12351222
    • Stumpf MP, Pybus OG. Genetic diversity and models of viral evolution for the hepatitis C virus. FEMS Microbiol Lett 2002; 214: 143-152 [PMID: 12351222]
    • (2002) FEMS Microbiol Lett , vol.214 , pp. 143-152
    • Stumpf, M.P.1    Pybus, O.G.2
  • 12
    • 40849097775 scopus 로고    scopus 로고
    • Rates of evolutionary change in viruses: Patterns and determinants
    • PMID: 18319742
    • Duffy S, Shackelton LA, Holmes EC. Rates of evolutionary change in viruses: patterns and determinants. Nat Rev Genet 2008; 9: 267-276 [PMID: 18319742]
    • (2008) Nat Rev Genet , vol.9 , pp. 267-276
    • Duffy, S.1    Shackelton, L.A.2    Holmes, E.C.3
  • 13
    • 84919382829 scopus 로고    scopus 로고
    • The Humoral Immune Response to HCV: Understanding is Key to Vaccine Development
    • PMID: 25426115
    • Cashman SB, Marsden BD, Dustin LB. The Humoral Immune Response to HCV: Understanding is Key to Vaccine Development. Front Immunol 2014; 5: 550 [PMID: 25426115 DOI: 10.3389/fmmu.2014.00550]
    • (2014) Front Immunol , vol.5 , pp. 550
    • Cashman, S.B.1    Marsden, B.D.2    Dustin, L.B.3
  • 14
    • 84894707183 scopus 로고    scopus 로고
    • Expanded classification of hepatitis C virus into 7 genotypes and 67 subtypes: Updated criteria and genotype assignment web resource
    • PMID: 24115039
    • Smith DB, Bukh J, Kuiken C, Muerhoff AS, Rice CM, Stapleton JT, Simmonds P. Expanded classification of hepatitis C virus into 7 genotypes and 67 subtypes: updated criteria and genotype assignment web resource. Hepatology 2014; 59: 318-327 [PMID: 24115039]
    • (2014) Hepatology , vol.59 , pp. 318-327
    • Smith, D.B.1    Bukh, J.2    Kuiken, C.3    Muerhoff, A.S.4    Rice, C.M.5    Stapleton, J.T.6    Simmonds, P.7
  • 15
    • 0034700083 scopus 로고    scopus 로고
    • Hepatitis C virus lacking the hypervariable region 1 of the second envelope protein is infectious and causes acute resolving or persistent infection in chimpanzees
    • PMID: 11078521
    • Forns X, Thimme R, Govindarajan S, Emerson SU, Purcell RH, Chisari FV, Bukh J. Hepatitis C virus lacking the hypervariable region 1 of the second envelope protein is infectious and causes acute resolving or persistent infection in chimpanzees. Proc Natl Acad Sci USA 2000; 97: 13318-13323 [PMID: 11078521]
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13318-13323
    • Forns, X.1    Thimme, R.2    Govindarajan, S.3    Emerson, S.U.4    Purcell, R.H.5    Chisari, F.V.6    Bukh, J.7
  • 16
    • 79551700091 scopus 로고    scopus 로고
    • Hypervariable region 1 differentially impacts viability of hepatitis C virus strains of genotypes 1 to 6 and impairs virus neutralization
    • PMID: 21123377
    • Prentoe J, Jensen TB, Meuleman P, Serre SB, Scheel TK, Leroux-Roels G, Gottwein JM, Bukh J. Hypervariable region 1 differentially impacts viability of hepatitis C virus strains of genotypes 1 to 6 and impairs virus neutralization. J Virol 2011; 85: 2224-2234 [PMID: 21123377]
    • (2011) J Virol , vol.85 , pp. 2224-2234
    • Prentoe, J.1    Jensen, T.B.2    Meuleman, P.3    Serre, S.B.4    Scheel, T.K.5    Leroux-Roels, G.6    Gottwein, J.M.7    Bukh, J.8
  • 19
    • 60149090028 scopus 로고    scopus 로고
    • Human occludin is a hepatitis C virus entry factor required for infection of mouse cells
    • PMID: 19182773
    • Ploss A, Evans MJ, Gaysinskaya VA, Panis M, You H, de Jong YP, Rice CM. Human occludin is a hepatitis C virus entry factor required for infection of mouse cells. Nature 2009; 457: 882-886 [PMID: 19182773]
    • (2009) Nature , vol.457 , pp. 882-886
    • Ploss, A.1    Evans, M.J.2    Gaysinskaya, V.A.3    Panis, M.4    You, H.5    De Jong, Y.P.6    Rice, C.M.7
  • 20
    • 84873659510 scopus 로고    scopus 로고
    • Clinical impact of hepatitis B and C virus envelope glycoproteins
    • PMID: 23429668
    • Jeulin H, Velay A, Murray J, Schvoerer E. Clinical impact of hepatitis B and C virus envelope glycoproteins. World J Gastroenterol 2013; 19: 654-664 [PMID: 23429668 DOI: 10.3748/wjg.v19.i5.654]
    • (2013) World J Gastroenterol , vol.19 , pp. 654-664
    • Jeulin, H.1    Velay, A.2    Murray, J.3    Schvoerer, E.4
  • 21
    • 84879549180 scopus 로고    scopus 로고
    • Identifcation of transferrin receptor 1 as a hepatitis C virus entry factor
    • PMID: 23754414
    • Martin DN, Uprichard SL. Identifcation of transferrin receptor 1 as a hepatitis C virus entry factor. Proc Natl Acad Sci USA 2013; 110: 10777-10782 [PMID: 23754414 DOI: 10.1073/pnas.1301764110]
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 10777-10782
    • Martin, D.N.1    Uprichard, S.L.2
  • 22
    • 84908363546 scopus 로고    scopus 로고
    • Hepatitis C vaccine. Need of the hour
    • PMID: 25424801
    • Verma R, Khanna P, Chawla S. Hepatitis C vaccine. Need of the hour. Hum Vaccin Immunother 2014; 10: 1927-1929 [PMID: 25424801 DOI: 10.4161/hv.29033]
    • (2014) Hum Vaccin Immunother , vol.10 , pp. 1927-1929
    • Verma, R.1    Khanna, P.2    Chawla, S.3
  • 23
    • 33644875265 scopus 로고    scopus 로고
    • Spontaneous viral clearance following acute hepatitis C infection: A systematic review of longitudinal studies
    • PMID: 16364080
    • Micallef JM, Kaldor JM, Dore GJ. Spontaneous viral clearance following acute hepatitis C infection: a systematic review of longitudinal studies. J Viral Hepat 2006; 13: 34-41 [PMID: 16364080]
    • (2006) J Viral Hepat , vol.13 , pp. 34-41
    • Micallef, J.M.1    Kaldor, J.M.2    Dore, G.J.3
  • 24
  • 26
    • 84954408206 scopus 로고    scopus 로고
    • WHO factsheet: HCV vaccines, number 164. Accessed February 27, 2015
    • WHO factsheet: HCV vaccines, number 164. Accessed February 27, 2015. Available from: URL: http://www.who.int/mediacentre/factsheets/fs164/en/
  • 27
    • 84897489963 scopus 로고    scopus 로고
    • Why is it so diffcult to develop a hepatitis C virus preventive vaccine?
    • PMID: 24829939
    • Zingaretti C, De Francesco R, Abrignani S. Why is it so diffcult to develop a hepatitis C virus preventive vaccine? Clin Microbiol Infect 2014; 20 Suppl 5: 103-109 [PMID: 24829939]
    • (2014) Clin Microbiol Infect , vol.20 , pp. 103-109
    • Zingaretti, C.1    De Francesco, R.2    Abrignani, S.3
  • 29
    • 84921492544 scopus 로고    scopus 로고
    • Is hepatitis C virus eradication around the corner only 25 years after its discovery?
    • PMID: 25249016
    • Ippolito G, Capobianchi MR, Lanini S, Antonelli G. Is hepatitis C virus eradication around the corner only 25 years after its discovery? Int J Antimicrob Agents 2015; 45: 111-112 [PMID: 25249016 DOI: 10.1016/j.ijantimicag.2014.09.001]
    • (2015) Int J Antimicrob Agents , vol.45 , pp. 111-112
    • Ippolito, G.1    Capobianchi, M.R.2    Lanini, S.3    Antonelli, G.4
  • 30
    • 79956138217 scopus 로고    scopus 로고
    • Progress in the development of preventive and therapeutic vaccines for hepatitis C virus
    • PMID: 21236312
    • Torresi J, Johnson D, Wedemeyer H. Progress in the development of preventive and therapeutic vaccines for hepatitis C virus. J Hepatol 2011; 54: 1273-1285 [PMID: 21236312 DOI: 10.1016/j.jhep.2010.09.040]
    • (2011) J Hepatol , vol.54 , pp. 1273-1285
    • Torresi, J.1    Johnson, D.2    Wedemeyer, H.3
  • 31
    • 84885335829 scopus 로고    scopus 로고
    • Hepatitis C virus infection and related liver disease: The quest for the best animal model
    • PMID: 23898329
    • Mailly L, Robinet E, Meuleman P, Baumert TF, Zeisel MB. Hepatitis C virus infection and related liver disease: the quest for the best animal model. Front Microbiol 2013; 4: 213 [PMID: 23898329 DOI: 10.3389/fmicb.2013.00212]
    • (2013) Front Microbiol , vol.4 , pp. 213
    • Mailly, L.1    Robinet, E.2    Meuleman, P.3    Baumert, T.F.4    Zeisel, M.B.5
  • 32
    • 84896977436 scopus 로고    scopus 로고
    • The past, present and future of neutralizing antibodies for hepatitis C virus
    • PMID: 24583033
    • Ball JK, Tarr AW, McKeating JA. The past, present and future of neutralizing antibodies for hepatitis C virus. Antiviral Res 2014; 105: 100-111 [PMID: 24583033 DOI: 10.1016/j.antiviral.2014.02.013]
    • (2014) Antiviral Res , vol.105 , pp. 100-111
    • Ball, J.K.1    Tarr, A.W.2    McKeating, J.A.3
  • 33
    • 84907541219 scopus 로고    scopus 로고
    • Immune control and failure in HCV infection-tipping the balance
    • PMID: 25015956
    • Dustin LB, Cashman SB, Laidlaw SM. Immune control and failure in HCV infection-tipping the balance. J Leukoc Biol 2014; 96: 535-548 [PMID: 25015956 DOI: 10.1189/jlb.4RI0214-126R]
    • (2014) J Leukoc Biol , vol.96 , pp. 535-548
    • Dustin, L.B.1    Cashman, S.B.2    Laidlaw, S.M.3
  • 34
    • 57449102983 scopus 로고    scopus 로고
    • Hepatitis C virus (HCV): A review of immunological aspects
    • PMID: 19065353
    • Irshad M, Khushboo I, Singh S, Singh S. Hepatitis C virus (HCV): a review of immunological aspects. Int Rev Immunol 2008; 27: 497-517 [PMID: 19065353 DOI: 10.1080/08830180802432178]
    • (2008) Int Rev Immunol , vol.27 , pp. 497-517
    • Irshad, M.1    Khushboo, I.2    Singh, S.3    Singh, S.4
  • 35
    • 68849111675 scopus 로고    scopus 로고
    • Hepatitis C virus versus innate and adaptive immune responses: A tale of coevolution and coexistence
    • PMID: 19587449
    • Rehermann B. Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence. J Clin Invest 2009; 119: 1745-1754 [PMID: 19587449 DOI: 10.1172/JCI39133]
    • (2009) J Clin Invest , vol.119 , pp. 1745-1754
    • Rehermann, B.1
  • 36
    • 84880276248 scopus 로고    scopus 로고
    • Pathogenesis of chronic viral hepatitis: Differential roles of T cells and NK cells
    • PMID: 23836236
    • Rehermann B. Pathogenesis of chronic viral hepatitis: differential roles of T cells and NK cells. Nat Med 2013; 19: 859-868 [PMID: 23836236 DOI: 10.1038/nm.3251]
    • (2013) Nat Med , vol.19 , pp. 859-868
    • Rehermann, B.1
  • 37
    • 84876514888 scopus 로고    scopus 로고
    • Adaptive immune responses in hepatitis C virus infection
    • PMID: 23463204
    • Neumann-Haefelin C, Thimme R. Adaptive immune responses in hepatitis C virus infection. Curr Top Microbiol Immunol 2013; 369: 243-262 [PMID: 23463204 DOI: 10.1007/978-3-642-27340-7-10]
    • (2013) Curr Top Microbiol Immunol , vol.369 , pp. 243-262
    • Neumann-Haefelin, C.1    Thimme, R.2
  • 38
    • 0038543543 scopus 로고    scopus 로고
    • Memory CD8+ T cells are required for protection from persistent hepatitis C virus infection
    • PMID: 12810686
    • Shoukry NH, Grakoui A, Houghton M, Chien DY, Ghrayeb J, Reimann KA, Walker CM. Memory CD8+ T cells are required for protection from persistent hepatitis C virus infection. J Exp Med 2003; 197: 1645-1655 [PMID: 12810686]
    • (2003) J Exp Med , vol.197 , pp. 1645-1655
    • Shoukry, N.H.1    Grakoui, A.2    Houghton, M.3    Chien, D.Y.4    Ghrayeb, J.5    Reimann, K.A.6    Walker, C.M.7
  • 39
    • 84892449551 scopus 로고    scopus 로고
    • Immune responses to HCV and other hepatitis viruses
    • PMID: 24439265
    • Park SH, Rehermann B. Immune responses to HCV and other hepatitis viruses. Immunity 2014; 40: 13-24 [PMID: 24439265 DOI: 10.1016/j.immuni.2013.12.010]
    • (2014) Immunity , vol.40 , pp. 13-24
    • Park, S.H.1    Rehermann, B.2
  • 40
    • 72249087933 scopus 로고    scopus 로고
    • Spontaneous control of primary hepatitis C virus infection and immunity against persistent reinfection
    • PMID: 19782080
    • Osburn WO, Fisher BE, Dowd KA, Urban G, Liu L, Ray SC, Thomas DL, Cox AL. Spontaneous control of primary hepatitis C virus infection and immunity against persistent reinfection. Gastroenterology 2010; 138: 315-324 [PMID: 19782080 DOI: 10.1053/j.gastro.2009.09.017]
    • (2010) Gastroenterology , vol.138 , pp. 315-324
    • Osburn, W.O.1    Fisher, B.E.2    Dowd, K.A.3    Urban, G.4    Liu, L.5    Ray, S.C.6    Thomas, D.L.7    Cox, A.L.8
  • 42
    • 84896974296 scopus 로고    scopus 로고
    • Clearance of hepatitis C infection is associated with the early appearance of broad neutralizing antibody responses
    • PMID: 24425349
    • Osburn WO, Snider AE, Wells BL, Latanich R, Bailey JR, Thomas DL, Cox AL, Ray SC. Clearance of hepatitis C infection is associated with the early appearance of broad neutralizing antibody responses. Hepatology 2014; 59: 2140-2151 [PMID: 24425349 DOI: 10.1002/hep.27013]
    • (2014) Hepatology , vol.59 , pp. 2140-2151
    • Osburn, W.O.1    Snider, A.E.2    Wells, B.L.3    Latanich, R.4    Bailey, J.R.5    Thomas, D.L.6    Cox, A.L.7    Ray, S.C.8
  • 43
    • 0028140138 scopus 로고
    • Neutralizing antibodies against hepatitis C virus and the emergence of neutralization escape mutant viruses
    • PMID: 8107212
    • Shimizu YK, Hijikata M, Iwamoto A, Alter HJ, Purcell RH, Yoshikura H. Neutralizing antibodies against hepatitis C virus and the emergence of neutralization escape mutant viruses. J Virol 1994; 68: 1494-1500 [PMID: 8107212]
    • (1994) J Virol , vol.68 , pp. 1494-1500
    • Shimizu, Y.K.1    Hijikata, M.2    Iwamoto, A.3    Alter, H.J.4    Purcell, R.H.5    Yoshikura, H.6
  • 45
    • 37849016609 scopus 로고    scopus 로고
    • Identification of a broadly cross-reacting and neutralizing human monoclonal antibody directed against the hepatitis C virus E2 protein
    • PMID: 17989176
    • Perotti M, Mancini N, Diotti RA, Tarr AW, Ball JK, Owsianka A, Adair R, Patel AH, Clementi M, Burioni R. Identification of a broadly cross-reacting and neutralizing human monoclonal antibody directed against the hepatitis C virus E2 protein. J Virol 2008; 82: 1047-1052 [PMID: 17989176]
    • (2008) J Virol , vol.82 , pp. 1047-1052
    • Perotti, M.1    Mancini, N.2    Diotti, R.A.3    Tarr, A.W.4    Ball, J.K.5    Owsianka, A.6    Adair, R.7    Patel, A.H.8    Clementi, M.9    Burioni, R.10
  • 49
    • 84863183220 scopus 로고    scopus 로고
    • Spontaneous clearance of chronic hepatitis C virus infection is associated with appearance of neutralizing antibodies and reversal of T-cell exhaustion
    • PMID: 22293431
    • Raghuraman S, Park H, Osburn WO, Winkelstein E, Edlin BR, Rehermann B. Spontaneous clearance of chronic hepatitis C virus infection is associated with appearance of neutralizing antibodies and reversal of T-cell exhaustion. J Infect Dis 2012; 205: 763-771 [PMID: 22293431]
    • (2012) J Infect Dis , vol.205 , pp. 763-771
    • Raghuraman, S.1    Park, H.2    Osburn, W.O.3    Winkelstein, E.4    Edlin, B.R.5    Rehermann, B.6
  • 50
    • 33847015308 scopus 로고    scopus 로고
    • Hepatitis C virus continuously escapes from neutralizing antibody and T-cell responses during chronic infection in vivo
    • PMID: 17258731
    • von Hahn T, Yoon JC, Alter H, Rice CM, Rehermann B, Balfe P, McKeating JA. Hepatitis C virus continuously escapes from neutralizing antibody and T-cell responses during chronic infection in vivo. Gastroenterology 2007; 132: 667-678 [PMID: 17258731]
    • (2007) Gastroenterology , vol.132 , pp. 667-678
    • Von Hahn, T.1    Yoon, J.C.2    Alter, H.3    Rice, C.M.4    Rehermann, B.5    Balfe, P.6    McKeating, J.A.7
  • 51
    • 34547098102 scopus 로고    scopus 로고
    • The neutralizing activity of anti-hepatitis C virus antibodies is modulated by specifc glycans on the E2 envelope protein
    • PMID: 17522218
    • Helle F, Goffard A, Morel V, Duverlie G, McKeating J, Keck Z Y, Foung S, Penin F, Dubuisson J, Voisset C. The neutralizing activity of anti-hepatitis C virus antibodies is modulated by specifc glycans on the E2 envelope protein. J Virol 2007; 81: 8101-8111 [PMID: 17522218]
    • (2007) J Virol , vol.81 , pp. 8101-8111
    • Helle, F.1    Goffard, A.2    Morel, V.3    Duverlie, G.4    McKeating, J.5    Keck, Z.Y.6    Foung, S.7    Penin, F.8    Dubuisson, J.9    Voisset, C.10
  • 52
    • 33144465371 scopus 로고    scopus 로고
    • Association between hepatitis C virus and very-low-density lipoprotein (VLDL)/LDL analyzed in iodixanol density gradients
    • PMID: 16474148
    • Nielsen SU, Bassendine MF, Burt AD, Martin C, Pumeechockchai W, Toms GL. Association between hepatitis C virus and very-low-density lipoprotein (VLDL)/LDL analyzed in iodixanol density gradients. J Virol 2006; 80: 2418-2428 [PMID: 16474148]
    • (2006) J Virol , vol.80 , pp. 2418-2428
    • Nielsen, S.U.1    Bassendine, M.F.2    Burt, A.D.3    Martin, C.4    Pumeechockchai, W.5    Toms, G.L.6
  • 54
    • 35448947907 scopus 로고    scopus 로고
    • The scavenger receptor BI and its ligand, HDL: Partners in crime against HCV neutralizing antibodies
    • PMID: 17958646
    • Dreux M, Cosset FL. The scavenger receptor BI and its ligand, HDL: partners in crime against HCV neutralizing antibodies. J Viral Hepat 2007; 14 Suppl 1: 68-76 [PMID: 17958646]
    • (2007) J Viral Hepat , vol.14 , pp. 68-76
    • Dreux, M.1    Cosset, F.L.2
  • 59
    • 84877351660 scopus 로고    scopus 로고
    • Hepatitis C virus suppresses C9 complement synthesis and impairs membrane attack complex function
    • PMID: 23487461
    • Kim H, Meyer K, Di Bisceglie AM, Ray R. Hepatitis C virus suppresses C9 complement synthesis and impairs membrane attack complex function. J Virol 2013; 87: 5858-5867 [PMID: 23487461]
    • (2013) J Virol , vol.87 , pp. 5858-5867
    • Kim, H.1    Meyer, K.2    Di Bisceglie, A.M.3    Ray, R.4
  • 60
    • 84880258824 scopus 로고    scopus 로고
    • Hepatitis C virus infection upregulates CD55 expression on the hepatocyte surface and promotes association with virus particles
    • PMID: 23658447
    • Mazumdar B, Kim H, Meyer K, Bose SK, Di Bisceglie AM, Ray RB, Diamond MS, Atkinson JP, Ray R. Hepatitis C virus infection upregulates CD55 expression on the hepatocyte surface and promotes association with virus particles. J Virol 2013; 87: 7902-7910 [PMID: 23658447]
    • (2013) J Virol , vol.87 , pp. 7902-7910
    • Mazumdar, B.1    Kim, H.2    Meyer, K.3    Bose, S.K.4    Di Bisceglie, A.M.5    Ray, R.B.6    Diamond, M.S.7    Atkinson, J.P.8    Ray, R.9
  • 61
    • 84880619779 scopus 로고    scopus 로고
    • Ever closer to a prophylactic vaccine for HCV
    • PMID: 23651228
    • Swadling L, Klenerman P, Barnes E. Ever closer to a prophylactic vaccine for HCV. Expert Opin Biol Ther 2013; 13: 1109-1124 [PMID: 23651228 DOI: 10.1517/14712598.2013.791277]
    • (2013) Expert Opin Biol Ther , vol.13 , pp. 1109-1124
    • Swadling, L.1    Klenerman, P.2    Barnes, E.3
  • 63
    • 84873112056 scopus 로고    scopus 로고
    • Hepatitis C virus vaccines in the era of new direct-acting antivirals
    • PMID: 23363265
    • Shi C, Ploss A. Hepatitis C virus vaccines in the era of new direct-acting antivirals. Expert Rev Gastroenterol Hepatol 2013; 7: 171-185 [PMID: 23363265 DOI: 10.1586/egh.12.72]
    • (2013) Expert Rev Gastroenterol Hepatol , vol.7 , pp. 171-185
    • Shi, C.1    Ploss, A.2
  • 64
    • 22344448015 scopus 로고    scopus 로고
    • Mutational escape from CD8+ T cell immunity: HCV evolution, from chimpanzees to man
    • PMID: 15939787
    • Bowen DG, Walker CM. Mutational escape from CD8+ T cell immunity: HCV evolution, from chimpanzees to man. J Exp Med 2005; 201: 1709-1714 [PMID: 15939787]
    • (2005) J Exp Med , vol.201 , pp. 1709-1714
    • Bowen, D.G.1    Walker, C.M.2
  • 66
    • 84873633268 scopus 로고    scopus 로고
    • Cellular immunogenicity of a multi-epitope peptide vaccine candidate based on hepatitis C virus NS5A, NS4B and core proteins in HHD-2 mice
    • PMID: 23333413
    • Huang XJ, Lü X, Lei YF, Yang J, Yao M, Lan HY, Zhang JM, Jia ZS, Yin W, Xu ZK. Cellular immunogenicity of a multi-epitope peptide vaccine candidate based on hepatitis C virus NS5A, NS4B and core proteins in HHD-2 mice. J Virol Methods 2013; 189: 47-52 [PMID: 23333413 DOI: 10.1016/j.jviromet.2013.01.003]
    • (2013) J Virol Methods , vol.189 , pp. 47-52
    • Huang, X.J.1    Lü, X.2    Lei, Y.F.3    Yang, J.4    Yao, M.5    Lan, H.Y.6    Zhang, J.M.7    Jia, Z.S.8    Yin, W.9    Xu, Z.K.10
  • 67
    • 84863774072 scopus 로고    scopus 로고
    • Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses
    • PMID: 22798606
    • Burton DR, Poignard P, Stanfield RL, Wilson IA. Broadly neutralizing antibodies present new prospects to counter highly antigenically diverse viruses. Science 2012; 337: 183-186 [PMID: 22798606]
    • (2012) Science , vol.337 , pp. 183-186
    • Burton, D.R.1    Poignard, P.2    Stanfield, R.L.3    Wilson, I.A.4
  • 68
    • 81855190655 scopus 로고    scopus 로고
    • Advances in hepatitis C virus vaccines, Part one: Advances in basic knowledge for hepatitis C virus vaccine design
    • PMID: 22022980
    • Roohvand F, Kossari N. Advances in hepatitis C virus vaccines, Part one: Advances in basic knowledge for hepatitis C virus vaccine design. Expert Opin Ther Pat 2011; 21: 1811-1830 [PMID: 22022980 DOI: 10.1517/13543776.2011.630662]
    • (2011) Expert Opin Ther Pat , vol.21 , pp. 1811-1830
    • Roohvand, F.1    Kossari, N.2
  • 70
    • 84859646587 scopus 로고    scopus 로고
    • Advances in hepatitis C virus vaccines, part two: Advances in hepatitis C virus vaccine formulations and modalities
    • PMID: 22455502
    • Roohvand F, Kossari N. Advances in hepatitis C virus vaccines, part two: advances in hepatitis C virus vaccine formulations and modalities. Expert Opin Ther Pat 2012; 22: 391-415 [PMID: 22455502 DOI: 10.1517/13543776.2012.673589]
    • (2012) Expert Opin Ther Pat , vol.22 , pp. 391-415
    • Roohvand, F.1    Kossari, N.2
  • 71
    • 84876723002 scopus 로고    scopus 로고
    • Induction of humoral and cellular immune responses against hepatitis C virus by vaccination with replicon particles derived from Sindbis-like virus XJ-160
    • PMID: 23250650
    • Zhu W, Fu J, Lu J, Deng Y, Wang H, Wei Y, Deng L, Tan W, Liang G. Induction of humoral and cellular immune responses against hepatitis C virus by vaccination with replicon particles derived from Sindbis-like virus XJ-160. Arch Virol 2013; 158: 1013-1019 [PMID: 23250650 DOI: 10.1007/s00705-012-1564-8]
    • (2013) Arch Virol , vol.158 , pp. 1013-1019
    • Zhu, W.1    Fu, J.2    Lu, J.3    Deng, Y.4    Wang, H.5    Wei, Y.6    Deng, L.7    Tan, W.8    Liang, G.9
  • 72
    • 52349087506 scopus 로고    scopus 로고
    • Induction of multispecifc Th-1 type immune response against HCV in mice by protein immunization using CpG and Montanide ISA 720 as adjuvants
    • PMID: 18675871
    • Qiu Q, Wang RY, Jiao X, Jin B, Sugauchi F, Grandinetti T, Alter HJ, Shih JW. Induction of multispecifc Th-1 type immune response against HCV in mice by protein immunization using CpG and Montanide ISA 720 as adjuvants. Vaccine 2008; 26: 5527-5534 [PMID: 18675871 DOI: 10.1016/j.vaccine.2008.07.034]
    • (2008) Vaccine , vol.26 , pp. 5527-5534
    • Qiu, Q.1    Wang, R.Y.2    Jiao, X.3    Jin, B.4    Sugauchi, F.5    Grandinetti, T.6    Alter, H.J.7    Shih, J.W.8
  • 73
    • 84883741031 scopus 로고    scopus 로고
    • Therapeutic DNA vaccination using in vivo electroporation followed by standard of care therapy in patients with genotype 1 chronic hepatitis C
    • PMID: 23752314
    • Weiland O, Ahlén G, Diepolder H, Jung MC, Levander S, Fons M, Mathiesen I, Sardesai N Y, Vahlne A, Frelin L, Sällberg M. Therapeutic DNA vaccination using in vivo electroporation followed by standard of care therapy in patients with genotype 1 chronic hepatitis C. Mol Ther 2013; 21: 1796-1805 [PMID: 23752314 DOI: 10.1038/mt.2013.119]
    • (2013) Mol Ther , vol.21 , pp. 1796-1805
    • Weiland, O.1    Ahlén, G.2    Diepolder, H.3    Jung, M.C.4    Levander, S.5    Fons, M.6    Mathiesen, I.7    Sardesai, N.Y.8    Vahlne, A.9    Frelin, L.10    Sällberg, M.11
  • 74
    • 78650536657 scopus 로고    scopus 로고
    • Prospects for prophylactic and therapeutic vaccines against the hepatitis C viruses
    • PMID: 21198667
    • Houghton M. Prospects for prophylactic and therapeutic vaccines against the hepatitis C viruses. Immunol Rev 2011; 239: 99-108 [PMID: 21198667 DOI: 10.1111/j.1600-065X.2010.00977.x]
    • (2011) Immunol Rev , vol.239 , pp. 99-108
    • Houghton, M.1
  • 76
    • 80052894158 scopus 로고    scopus 로고
    • Vaccine-induced cross-genotype reactive neutralizing antibodies against hepatitis C virus
    • PMID: 21917891
    • Meunier JC, Gottwein JM, Houghton M, Russell RS, Emerson SU, Bukh J, Purcell RH. Vaccine-induced cross-genotype reactive neutralizing antibodies against hepatitis C virus. J Infect Dis 2011; 204: 1186-1190 [PMID: 21917891 DOI: 10.1093/infdis/jir511]
    • (2011) J Infect Dis , vol.204 , pp. 1186-1190
    • Meunier, J.C.1    Gottwein, J.M.2    Houghton, M.3    Russell, R.S.4    Emerson, S.U.5    Bukh, J.6    Purcell, R.H.7
  • 77
    • 80051721226 scopus 로고    scopus 로고
    • Immunization of human volunteers with hepatitis C virus envelope glycoproteins elicits antibodies that cross-neutralize heterologous virus strains
    • PMID: 21788452
    • Stamataki Z, Coates S, Abrignani S, Houghton M, McKeating JA. Immunization of human volunteers with hepatitis C virus envelope glycoproteins elicits antibodies that cross-neutralize heterologous virus strains. J Infect Dis 2011; 204: 811-813 [PMID: 21788452 DOI: 10.1093/infdis/jir399]
    • (2011) J Infect Dis , vol.204 , pp. 811-813
    • Stamataki, Z.1    Coates, S.2    Abrignani, S.3    Houghton, M.4    McKeating, J.A.5
  • 78
    • 84911489136 scopus 로고    scopus 로고
    • Recombinant hepatitis C virus envelope glycoprotein vaccine elicits antibodies targeting multiple epitopes on the envelope glycoproteins associated with broad cross-neutralization
    • PMID: 25275133
    • Wong JA, Bhat R, Hockman D, Logan M, Chen C, Levin A, Frey SE, Belshe RB, Tyrrell DL, Law JL, Houghton M. Recombinant hepatitis C virus envelope glycoprotein vaccine elicits antibodies targeting multiple epitopes on the envelope glycoproteins associated with broad cross-neutralization. J Virol 2014; 88: 14278-14288 [PMID: 25275133 DOI: 10.1128/JVI.01911-14]
    • (2014) J Virol , vol.88 , pp. 14278-14288
    • Wong, J.A.1    Bhat, R.2    Hockman, D.3    Logan, M.4    Chen, C.5    Levin, A.6    Frey, S.E.7    Belshe, R.B.8    Tyrrell, D.L.9    Law, J.L.10    Houghton, M.11
  • 80
    • 84899044314 scopus 로고    scopus 로고
    • Viral hepatitis: Cell-culture-derived HCV-A promising vaccine antigen
    • PMID: 23897287
    • Gottwein JM, Bukh J. Viral hepatitis: Cell-culture-derived HCV-A promising vaccine antigen. Nat Rev Gastroenterol Hepatol 2013; 10: 508-509 [PMID: 23897287 DOI: 10.1038/nrgastro.2013.136]
    • (2013) Nat Rev Gastroenterol Hepatol , vol.10 , pp. 508-509
    • Gottwein, J.M.1    Bukh, J.2
  • 82
    • 67349209526 scopus 로고    scopus 로고
    • Chimeric hepatitis B and C viruses envelope proteins can form subviral particles: Implications for the design of new vaccine strategies
    • PMID: 19356608
    • Patient R, Hourioux C, Vaudin P, Pagès JC, Roingeard P. Chimeric hepatitis B and C viruses envelope proteins can form subviral particles: implications for the design of new vaccine strategies. N Biotechnol 2009; 25: 226-234 [PMID: 19356608 DOI: 10.1016/j.nbt.2009.01.001]
    • (2009) N Biotechnol , vol.25 , pp. 226-234
    • Patient, R.1    Hourioux, C.2    Vaudin, P.3    Pagès, J.C.4    Roingeard, P.5
  • 84
    • 28844440938 scopus 로고    scopus 로고
    • In vivo clearance of hepatitis C virus nonstructural 3/4A-expressing hepatocytes by DNA vaccine-primed cytotoxic T lymphocytes
    • PMID: 16288375
    • Ahlen G, Nystrom J, Pult I, Frelin L, Hultgren C, Sallberg M. In vivo clearance of hepatitis C virus nonstructural 3/4A-expressing hepatocytes by DNA vaccine-primed cytotoxic T lymphocytes. J Infect Dis 2005; 192: 2112-2116 [PMID: 16288375]
    • (2005) J Infect Dis , vol.192 , pp. 2112-2116
    • Ahlen, G.1    Nystrom, J.2    Pult, I.3    Frelin, L.4    Hultgren, C.5    Sallberg, M.6
  • 85
    • 73949116981 scopus 로고    scopus 로고
    • Viruses as vaccine vectors for infectious diseases and cancer
    • PMID: 19966816
    • Draper SJ, Heeney JL. Viruses as vaccine vectors for infectious diseases and cancer. Nat Rev Microbiol 2010; 8: 62-73 [PMID: 19966816 DOI: 10.1038/nrmicro2240]
    • (2010) Nat Rev Microbiol , vol.8 , pp. 62-73
    • Draper, S.J.1    Heeney, J.L.2
  • 86
    • 84878804020 scopus 로고    scopus 로고
    • Prospects for prophylactic hepatitis C vaccines based on virus-like particles
    • PMID: 23406827
    • Beaumont E, Roingeard P. Prospects for prophylactic hepatitis C vaccines based on virus-like particles. Hum Vaccin Immunother 2013; 9: 1112-1118 [PMID: 23406827 DOI: 10.4161/hv.23900]
    • (2013) Hum Vaccin Immunother , vol.9 , pp. 1112-1118
    • Beaumont, E.1    Roingeard, P.2
  • 89
    • 43549113865 scopus 로고    scopus 로고
    • Strategies for loading dendritic cells with hepatitis C NS5a antigen and inducing protective immunity
    • PMID: 18221298
    • Yu H, Babiuk LA, van Drunen Littel-van den Hurk S. Strategies for loading dendritic cells with hepatitis C NS5a antigen and inducing protective immunity. J Viral Hepat 2008; 15: 459-470 [PMID: 18221298 DOI: 10.1111/j.1365-2893.2008.00959.x]
    • (2008) J Viral Hepat , vol.15 , pp. 459-470
    • Yu, H.1    Babiuk, L.A.2    Van Drunen Littel-Van Den Hurk, S.3
  • 90
    • 84905862543 scopus 로고    scopus 로고
    • Dendritic cell-mediated, DNA-based vaccination against hepatitis C induces the multi-epitope-specific response of humanized, HLA transgenic mice
    • PMID: 25111185
    • Mishra S, Lavelle BJ, Desrosiers J, Ardito MT, Terry F, Martin WD, De Groot AS, Gregory SH. Dendritic cell-mediated, DNA-based vaccination against hepatitis C induces the multi-epitope-specific response of humanized, HLA transgenic mice. PLoS One 2014; 9: e104606 [PMID: 25111185 DOI: 10.1371/journal. pone.0104606]
    • (2014) PLoS One , vol.9 , pp. e104606
    • Mishra, S.1    Lavelle, B.J.2    Desrosiers, J.3    Ardito, M.T.4    Terry, F.5    Martin, W.D.6    De Groot, A.S.7    Gregory, S.H.8
  • 92
    • 84922938955 scopus 로고    scopus 로고
    • Chimeric hepatitis B virus (HBV)/hepatitis C virus (HCV) subviral envelope particles induce effcient anti-HCV antibody production in animals pre-immunized with HBV vaccine
    • PMID: 25596457
    • Beaumont E, Roingeard P. Chimeric hepatitis B virus (HBV)/hepatitis C virus (HCV) subviral envelope particles induce effcient anti-HCV antibody production in animals pre-immunized with HBV vaccine. Vaccine 2015; 33: 973-976 [PMID: 25596457 DOI: 10.1016/j.vaccine.2015.01.007]
    • (2015) Vaccine , vol.33 , pp. 973-976
    • Beaumont, E.1    Roingeard, P.2
  • 93
    • 84921624876 scopus 로고    scopus 로고
    • Hepatitis C vaccine clinical trials among people who use drugs: Potential for participation and involvement in recruitment
    • PMID: 25553715
    • Young AM, Stephens DB, Khaleel HA, Havens JR. Hepatitis C vaccine clinical trials among people who use drugs: potential for participation and involvement in recruitment. Contemp Clin Trials 2015; 41: 9-16 [PMID: 25553715 DOI: 10.1016/j.cct.2014.12.015]
    • (2015) Contemp Clin Trials , vol.41 , pp. 9-16
    • Young, A.M.1    Stephens, D.B.2    Khaleel, H.A.3    Havens, J.R.4
  • 101
    • 84859432807 scopus 로고    scopus 로고
    • Failure of innate and adaptive immune responses in controlling hepatitis C virus infection
    • PMID: 22142141
    • Thimme R, Binder M, Bartenschlager R. Failure of innate and adaptive immune responses in controlling hepatitis C virus infection. FEMS Microbiol Rev 2012; 36: 663-683 [PMID: 22142141 DOI: 10.1111/j.1574-6976.2011.00319.x]
    • (2012) FEMS Microbiol Rev , vol.36 , pp. 663-683
    • Thimme, R.1    Binder, M.2    Bartenschlager, R.3
  • 102
    • 84888408660 scopus 로고    scopus 로고
    • Immunogenicity evaluation of a DNA vaccine expressing the hepatitis C virus non-structural protein 2 gene in C57BL/6 mice
    • PMID: 24375156
    • Gorzin Z, Gorzin AA, Tabarraei A, Behnampour N, Irani S, Ghaemi A. Immunogenicity evaluation of a DNA vaccine expressing the hepatitis C virus non-structural protein 2 gene in C57BL/6 mice. Iran Biomed J 2014; 18: 1-7 [PMID: 24375156]
    • (2014) Iran Biomed J , vol.18 , pp. 1-7
    • Gorzin, Z.1    Gorzin, A.A.2    Tabarraei, A.3    Behnampour, N.4    Irani, S.5    Ghaemi, A.6
  • 103
    • 84919783001 scopus 로고    scopus 로고
    • Hepatitis C virus. Strategies to evade antiviral responses
    • PMID: 25983854
    • Gokhale NS, Vazquez C, Horner SM. Hepatitis C Virus. Strategies to Evade Antiviral Responses. Future Virol 2014; 9: 1061-1075 [PMID: 25983854]
    • (2014) Future Virol , vol.9 , pp. 1061-1075
    • Gokhale, N.S.1    Vazquez, C.2    Horner, S.M.3
  • 104
    • 84954215381 scopus 로고    scopus 로고
    • Emerging roles of interferon-stimulated genes in the innate immune response to hepatitis C virus infection
    • Epub ahead of print [PMID: 25544499
    • Wong MT, Chen SS. Emerging roles of interferon-stimulated genes in the innate immune response to hepatitis C virus infection. Cell Mol Immunol 2014; Epub ahead of print [PMID: 25544499 DOI: 10.1038/cmi.2014.1]
    • (2014) Cell Mol Immunol
    • Wong, M.T.1    Chen, S.S.2


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